Effect of Suplatast Tosilate on Airway Hyperresponsiveness and Inflammation in Asthma Patients

REFERENCES

• Durham S.R., Kay A.B. Eosinophils, Bronchial Hyperreactivity and Late-Phase Asthmatic Reactions. Clin. Allergy 1985; 15: 411–418
   PubMedGoogle Scholar
• Maestrelli P., Saetta M., Di Stefano A., Calcagni P.G., Turato G., Ruggieri M.P., Roggeri A., Mapp C.E., Fabbri L.M. Comparison of Leukocyte Counts in Sputum, Bronchial Biopsies, and Bronchoalveolar Lavage. Am. J. Respir. Crit. Care Med. 1995; 152: 1926–1931
   PubMed Web of Science ®Google Scholar
• Kraneveld A.D., Folkerts G., van Oosterhout A.J.M., Nijkamp F.P. Airway Hyperresponsiveness: First Eosinophils and then Neuropeptides. Int. J. Immunopharmacol. 1997; 19: 517–527
   PubMed Web of Science ®Google Scholar
• Gleich G.J., Flavahan N.A., Fujisawa T., Vanhoutte P.M. The Eosinophils as a Mediator of Damage to Respiratory Epithelium: A Model for Bronchial Hyperreactivity. J. Allergy Clin. Immunol. 1988; 81: 776–781
   PubMed Web of Science ®Google Scholar
• Motojima S., Frigas E., Leogering D.A., Gleich G.J. Toxicity of Eosinophil Cationic Proteins for Guinea Pig Tracheal Epithelium In Vitro. Am. Rev. Respir. Dis. 1989; 139: 801–805
   PubMed Web of Science ®Google Scholar
• Aalvers R., DeMonchy J.G.R., Kauffman H.F., Smith M., Heikstra Y., Vrugt B., Timens W. Dynamics of Eosinophil Infiltration in the Bronchial Mucosa Before and After the Late Asthmatic Reaction. Eur. Respir. J. 1993; 6: 840–847
   PubMed Web of Science ®Google Scholar
• Yanagihara Y., Kiniwa M., Ikizawa K., Yamaya H., Shida T., Matsuura N., Koda A. Suppression of IgE by IPD–1151T (Suplatast Tosilate), a New Dimethylsulfonium Agent: (1) Regulation of Murine IgE Response. Jpn. J. Pharmacol. 1993; 61: 23–30
   PubMedGoogle Scholar
• Yanagihara Y., Kiniwa M., Ikizawa K., Shida T., Matsuura N., Koda A. Suppression of IgE by IPD-1151T (Suplatast Tosilate), a New Dimethylsulfonium Agent: (2) Regulation of Human IgE Response. Jpn. J. Pharmacol. 1993; 61: 31–39
   PubMedGoogle Scholar
• Oda N., Minoguchi K., Yokoe T., Hashimoto T., Wada K., Miyamoto M., Tanaka A., Kohno Y., Adachi M. Effect of Suplatast Tosilate (IPD-1151T) on Cytokine Production by Allergen-Specific Human Th1 and Th2 Cell Lines. Life Sci. 1999; 65: 763–770
   PubMed Web of Science ®Google Scholar
• Iijima H., Tamura G., Hsiue T.R., Liu Y., Taniguchi H., Shirato K. Suplatast Tosilate Inhibits Late Response and Airway Inflammation in Sensitized Guinea Pigs. Am. J. Respir. Crit. Care Med. 1999; 160: 331–335
   PubMed Web of Science ®Google Scholar
• Konno S., Asano K., Gonokami Y., Kurokawa M., Kawazu K., Adachi M. Effect of IPD-1151T (Suplatast Tosilate) on Airway Hyperresponsiveness in Mice. Jpn. J. Allergol. 1995; 44: 556–561
   PubMedGoogle Scholar
• Taniguchi H., Togawa M., Ohwada K., Kiniwa M., Matsuura N., Nagai H., Koda A. Suplatast Tosilate, a New Type of Antiallergic Agent, Prevents the Expression of Airway Hyperresponsiveness in Guinea Pigs. Eur. J. Pharmacol. 1996; 318: 447–454
   PubMed Web of Science ®Google Scholar
• Zhao G.D., Yokoyama A., Kohno N., Sakai K., Hamada H., Hiwada K. Effect of Suplatast Tosilate (IPD-1151T) on a Mouse Model of Asthma: Inhibition of Eosinophilic Inflammation and Bronchial Hyperresponsiveness. Int. Arch. Allergy Immunol. 2000; 121: 116–122
   PubMed Web of Science ®Google Scholar
• Takishima T., Hida W., Sasaki H., Suzuki S., Sasaki T. Direct-Writing Recorder of the Dose–Response Curves of the Airway to Methacholine. Chest 1981; 80: 600–606
   PubMed Web of Science ®Google Scholar
• Ishii M., Hida W., Suzuki S., Ichinose M., Sasaki H., Takishima T. Comparison of Intermittent and Continuous Inhalation Provocation Tests. Ann. Allergy 1989; 62: 223–228
   PubMedGoogle Scholar
• Kharitonov S.A., Alving K., Barnes P.J. Exhaled and Nasal Nitric Oxide Measurements: Recommendations. Eur. Respir. J. 1997; 10: 1683–1693
   PubMed Web of Science ®Google Scholar
• Yamaya H., Basaki Y., Togawa M., Kojima M., Kiniwa M., Matsuura N. Down-regulation of Th2 Cell-Mediated Murine Peritoneal Eosinophilia by Antiallergic Agents. Life Sci. 1995; 56: 1647–1654
   PubMed Web of Science ®Google Scholar
• Sano Y., Miyamoto T., Makino S. Anti-inflammatory Effect of Suplatast Tosilate on Mild Asthma. Chest 1997; 112: 862–863
   PubMed Web of Science ®Google Scholar
• Tamaoki J., Kondo M., Sakai N., Aoshiba K., Tagaya E., Nakata J., Isono K., Nagai A. Effect of Suplatast Tosilate, a Th2 Cytokine Inhibitor, on Steroid-Dependent Asthma: A Double-Blind Randomised Study. Lancet 2000; 356(9226)273–278
   PubMed Web of Science ®Google Scholar
• Shioya T., Kagaya M., Sano M., Ito T., Shindo T., Kashima M., Watanabe A., Sato K., Ito N., Sasaki M., Miura M. Effect of Suplatast Tosilate on Cough Variant Asthma. Allergology Int. 2000; 49: 89–92
   Google Scholar
• Gibson P.G., Girgis-Gabardo A., Morris M.M., Mattoli S., Kay J.M., Dolovich J., Denburg J., Hargreave F.E. Cellular Characteristics of Sputum from Patients with Asthma and Chronic Bronchitis. Thorax 1989; 44: 693–699
   PubMed Web of Science ®Google Scholar
• Pizzichini E., Pizzichini M.M.M., Efthimiadis A., Evans S., Morris M.M., Squillace D., Gleich G.J., Dolovich J., Hargerave F.E. Indices of Airway Inflammation in Induced Sputum: Reproducibility and Validity of Cell and Fluid-Phase Measurements. Am. J. Respir. Crit. Care Med. 1996; 154: 308–317
   PubMed Web of Science ®Google Scholar
• Fujisawa T., Terada A., Atsuta J., Iguchi K., Kamiya H., Sakurai M. Clinical Utility of Serum Levels of Eosinophil Cationic Protein (ECP) for Monitoring and Predicting Clinical Course in Childhood Asthma. Clin. Exp. Allergy 1998; 28: 19–25
   PubMed Web of Science ®Google Scholar
• Zimmerman B., Lanner A., Enander I., Zimmerman R.S., Peterson C.G., Ahlstedt S. Total Blood Eosinophils, Serum Eosinophil Cationic Protein and Eosinophil Protein X in Childhood Asthma: Relation to Disease Status and Therapy. Clin. Exp. Allergy 1993; 23: 564–570
   PubMed Web of Science ®Google Scholar
• Gustafsson L.E., Leone A.M., Persson M.G., Wiklund N.P., Moncada S. Endogenous Nitric Oxide is Present in the Exhaled Air of Rabbits, Guinea Pigs and Humans. Biochem. Biophys. Res. Commun. 1991; 181: 852–857
   PubMed Web of Science ®Google Scholar
• Leone A.M., Gustafsson L.E., Francis P.L., Persson M.G., Wiklund N.P., Moncada S. Nitric Oxide is Present in Exhaled Breath in Humans: Direct GC-MS Confirmation. Biochem. Biophys. Res. Commun. 1994; 201: 883–887
   PubMed Web of Science ®Google Scholar
• Alving K., Weitzberg E., Lundverg J.M. Increased Amount of Nitric Oxide in Exhaled Air of Asthmatics. Eur. Respir. J. 1993; 6: 1368–1370
   PubMed Web of Science ®Google Scholar
• Kharitonov S.A., Yates D.H., Robbins R.A., Logan-Sinclair R., Shinebourne E.A., Barnes P.J. Increased Nitric Oxide in Exhaled Air of Asthmatic Patients. Lancet 1994; 343: 133–135
   PubMed Web of Science ®Google Scholar
• Kharitonov S.A., Yates D.H., Barnes P.J. Inhaled Glucocorticosteroids Decrease Nitric Oxide in Exhaled Air of Asthmatic Patients. Am. J. Respir. Crit. Care Med. 1996; 153: 454–457
   PubMed Web of Science ®Google Scholar
• Massaro A.F., Mehta S., Lilly C.M., Kobzik L., Reilly J.J., Drazen J.M. Elevated Nitric Oxide Concentrations in Isolated Lower Airway Gas of Asthmatic Subjects. Am. J. Respir. Crit. Care Med. 1996; 153: 1510–1514
   PubMed Web of Science ®Google Scholar
• Venge P., Dahl R., Peterson C.G. Eosinophil Granule Proteins in Serum After Allergen Challenge of Asthmatic Patients and the Effects of Anti-asthmatic Medication. Int. Arch. Allergy Immunol. 1988; 87: 306–312
   Web of Science ®Google Scholar
• Iijima H., Tamura G., Hsiue T.R., Liu Y., Taniguchi H., Shirato K. Suplatast Tosilate Inhibits Late Response and Airway Inflammation in Sensitized Guinea Pigs. Am. J. Respir. Crit. Care Med. 1999; 160: 331–335
   PubMed Web of Science ®Google Scholar
• Boushey H.A., Holtzman M.J., Sheller J.R., Nadel J.A. Bronchial Hyperreactivity. Am. Rev. Respir. Dis. 1980; 121: 389–414
   PubMed Web of Science ®Google Scholar
• Holgate S.T., Beasley R., Twentymen O.P. The Pathogenesis and Significance of Bronchial Hyperresponsiveness in Airway Disease. Clin. Sci. 1987; 73: 561–572
   PubMed Web of Science ®Google Scholar
• Makino S. Clinical Significance of Bronchial Sensitivity to Acetylcholine and Histamine in Bronchial Asthma. J. Allergy 1966; 38: 127–142
   PubMedGoogle Scholar
• Spector S.L., Farr R.S. A Comparison of Methacholine and Histamine Inhalations in Asthmatics. J. Allergy Clin. Immunol. 1975; 56: 308–316
   PubMed Web of Science ®Google Scholar