147
Views
14
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Analysis of Sputum Cell Counts During Spontaneous Moderate Exacerbations of Asthma in Comparison to the Stable Phase

, , , , , , , , & show all
Pages 155-162 | Published online: 22 Apr 2003

References

  • Pin I, Freitag AP, O'Byrne PM, Girgis-Gabardo A, Watson RM, Dolovich J. Changes in the cellular profile of induced sputum after allergen-induced asthmatic responses. Am Rev Respir Dis 1992; 145: 1265–1269
  • Fahy JV, Liu J, Wong H, Boushey HA. Analysis of cellular and biochemical constituents of induced sputum after allergen challenge: a method for studying allergen airway inflammation. J Allergy Clin Immunol 1994; 93: 1031–1039
  • Gibson PG, Wong BJO, Hepperle MJE, Kline PA, Girgis-Gabardo A, Guyatt G, Dolovich J, Denburg JA, Ramsdale EH, Hargreave FE. A research method to induce and examine a mild exacerbation of asthma by withdrawal of inhaled corticosteroids. Clin Exp Allergy 1992; 22: 525–532
  • In't Veen JC, Smits HH, Hiemstra PS, Zwinderman AE, Sterk PJ, Bel EH. Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. Am J Respir Crit Care Med 1999; 160: 93–99
  • Pizzichini MMM, Pizzichini E, Clelland L, Efthimiadis A, Mahony J, Dolovich J, Hargreave FE. Sputum in severe exacerbation of asthma. Am J Respir Crit Care Med 1997; 155: 1501–1508
  • Turner MO, Hussack P, Sears MR, Dolovich J, Hargreave FE. Exacerbations of asthma without sputum eosinophilia. Thorax 1995; 50: 1057–1061
  • Pizzichini MMM, Pizzichini E, Efthimiadis A, Chauhan AJ, Johnston SL, Hussack P, Mahony J, Dolovich J, Hargreave FE. Asthma and natural colds. Inflammatory indices in induced sputum: a feasibility study. Am J Respir Crit Care Med 1998; 158: 1178–1184
  • Mcivor RA, Pizzichini E, Turner MO, Hussack P, Hargreave FE, Sears MR. Potential masking effects of salmeterol on airway inflammation in asthma. Am J Respir Crit Care Med 1998; 158: 924–930
  • Fahy JV, Kim KW, Liu J, Boushey HA. Prominent neutrofilic inflammation in sputum from subjects with asthma exacerbation. J Allergy Clin Immunol 1995; 95: 843–852
  • NHLBI. International consensus report on diagnosis and treatment of asthma. Eur Respir J 1992; 5: 601–641
  • Pin I, Gibson PG, Kolendowicz R, Girgis-Gabardo A, Denburg JA, Hargreave FE, Dolovich J. Use of induced sputum cell counts to investigate airway inflammation in asthma. Thorax 1992; 47: 25–29
  • Bacci E, Cianchetti S, Paggiaro PL, Carnevali S, Bancalari L, Dente FL, Di Franco A, Giannini D, Vagaggini B, Giuntini C. Comparison between hypertonic and isotonic saline-induced sputum in the evaluation of airway inflammation in subjects with moderate asthma. Clin Exp Allergy 1996; 26: 1395–1400
  • Bacci E, Cianchetti S, Bartoli ML, Carnevali S, Carletti AH, Di Franco A, Giannini D, Vagaggini B, Paggiaro PL. Reproducibility of induced sputum cell analysis in the evaluation of airway inflammation in asthma. Eur Respir J 1996; 9(Suppl 23)119s, (abstract)
  • Belda J, Leigh R, Parameswaran K, O'Byrne PM, Sears MR, Hargreave FE. Induced sputum cell counts in healthy adults. Am J Respir Crit Care Med 2000; 161: 475–478
  • Bacci E, Cianchetti S, Ruocco L, Bartoli ML, Carnevali S, Dente FL, Di Franco A, Giannini D, Marchioni P, Vagaggini B, Morelli MC, Paggiano PL. Comparison between eosinophilic markers in induced sputum and blood in asthmatic patients. Clin Exper Allergy 1998; 28: 1237–1243
  • Armitage P, Berry G. Statistical Methods in Medical Research. 2nd ed. Blackwell, Oxford 1994
  • Siegel S, Castellan NJ. Nonparametrics Statistics for the Behavioral Sciences. 2nd ed. McGraw-Hill libri Italia Rrl, Milano 1992
  • Twaddell SH, Gibson PG, Carty K, Wooley KL, Henry RL. Assessment of airway inflammation in children with acute asthma using induced sputum. Eur Respir J 1996; 9: 2104–2108
  • Sur S, Crotty TB, Kephart GM. Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa?. Am Rev Respir Dis 1993; 148: 713–719
  • Metzger WJ, Richerson HB, Worden K, Monick M, Hunninghake GW. Bronchoalveolar lavage of allergic asthmatic patients following allergen bronchoprovocation. Chest 1986; 89: 477–483
  • Cai Y, Carty K, Henry RL, Gibson PG. Persistence of sputum eosinophilia in children with controlled asthma when compared with healthy children. Eur Respir J 1998; 11: 848–853
  • Pizzichini E, Pizzichini MMM, Efthimiadis A, Dolovich J, Hargreave FE. Measuring airway inflammation in asthma: eosinophils and eosinophilic cationic protein in induced sputum compared with peripheral blood. J Allergy Clin Immunol 1997; 99: 539–544
  • Keatings VM, O'Connor BJ, Wright LG, Huston DP, Corrigan CJ, Barnes PJ. Late response to allergen is associated with increased concentration of sputum tumor necrosis factor-alpha and IL-5 in induced sputum. J Allergy Clin Immunol 1997; 5: 693–698
  • Jatakanon A, Lin S, Barnes PJ. Changes in sputum eosinophils predict loss of asthma control. Am J Respir Crit Care Med 2000; 61: 64–72
  • Pizzichini MM, Popov TA, Efthimiadis A, Hussack P, Evans S, Pizzichini E, Dolovich J, Hargreave FE. Spontaneous and induced sputum to measure indices of airway inflammation in asthma. Am J Respir Crit Care Med 1996; 154: 866–869

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.