272
Views
9
CrossRef citations to date
0
Altmetric
Original

TUBULAR CELL LESION, ALBUMINURIA, AND RENAL ALBUMIN HANDLING IN RATS TREATED WITH ADRIAMYCIN

, , B.S., , M.D., Ph.D., , B.S. & , M.D., Ph.D.
Pages 693-703 | Published online: 07 Jul 2009

REFERENCES

  • Eddy A A, McCulloch L, Liu E, Adams J. A relationship between proteinuria and acute tubulointerstitial disease in rats with experimental nephrotic syndrome. Am J Pathol 1991; 138: 1111–1123
  • Coimbra T M, Degiacobbi G, Gouveia M A, Lachat J J, Carvalho I F. Effect of urinary alkalinization on renal changes produced by cationic albumin. Nephron 1984; 38: 261–266
  • Eddy A A. Experimental insights into the tubulointerstitial disease accompanying primary glomerular lesions. J Am Soc Nephrol 1994; 5: 1273–1287
  • Remuzzi G, Ruggenenti P, Benigni A. Understanding the nature of renal disease progression. Kidney Int 1997; 51: 2–15
  • Eddy A A, Michael A. Acute tubulointerstititial nephritis associated with aminonucleoside nephrosis. Kidney Int 1988; 33: 14–23
  • Eddy A A, McCulloch L, Adams J, Liu E. Interstitial nephritis induced by protein-overload proteinuria. Am J Pathol 1989; 135: 719–733
  • Bertani T, Cutillo F, Zoja C, Broggini M, Remuzzi G. Tubulointerstitial lesions mediate renal damage in adriamycin glomerulopathy. Kidney Int 1986; 30: 488–496
  • Baroni E A, Costa R S, da Silva C GA, Coimbra T A. Heparin treatment reduces glomerular injury in rats with adriamycin-induced nephropathy but does not modify tubulointerstitial damage or renal production of transforming growth factor-beta. Nephron 2000; 84: 248–257
  • Zoja C, Donadelli R, Colleoni S, Figliuzzi M, Bonazzola S, Morigi M, Remuzzi G. Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kB activation. Kidney Int 1998; 53: 1608–1615
  • Zoja C, Morigi M, Figliuzzi M, Bruzzi I, Oldroyd S, Benigni A, Ronco P M, Remuzzi G. Proximal tubular cell synthesis and secretion of endothelin-1 on challenge with albumin and other proteins. Am J Kidney Dis 1995; 26: 934–941
  • Rangan G K, Wang Y, Tay Y-C, Harris D CH. Inhibition of nuclear factor-kB activation reduces cortical tubulointerstitial injury in proteinuric rats. Kidney Int 1999; 56: 118–134
  • Baroni E A, Costa R S, Volpini R A, Coimbra T M. Sodium bicarbonate treatment reduces renal injury, renal production of transforming growth factor-β, and urinary transforming growth factor-β excretion in rats with doxorubicin-induced nephropathy. Am J Kidney Dis 1999; 34: 328–337
  • Remuzi G, Zoja C, Remuzi A, Rossini M, Battaglia C, Broggini M, Bertani T. Low-protein diet prevents glomerular damage in adriamycin-treated rats. Kidney Int 1985; 28: 21–27
  • Okuda S, Nakamura T, Yamamoto T, Ruoslahti E, Border W A. Dietary protein restriction rapidly reduces TGF-β1 expression in experimental glomerulonephritis. Proc Natl Acad Sci USA 1991; 88: 9765–9769
  • Barretti P, Viero R M, Soares V A. Effects of dietary protein angiotensin I converting enzyme inhibition and mesangial overload on the progression of adriamycin-induced nephropathy. Braz J Med Biol Res 1995; 28: 39–50
  • Christensen E I, Carone F A, Rennke H G. Effect of molecular charge on endocytic uptake of ferritin in renal proximal tubule cells. Lab Invest 1981; 44: 351–358
  • Maack T, Hyang-Park C, Camargo M G. Renal filtration, transport, and metabolism of proteins. The Kidney, Physiology and Pathophysiology, D W Seldin, G Giebisch. Raven Press, New York 1992; 3005–3038
  • Laurell C B. Electroimmunoassay. Scand J Clin Lab Invest 1972; 124(suppl.)21–23
  • Haygen H N. The determination of “endogenous creatinine” in plasma and urine. Scand J Clin Lab Invest 1953; 5: 48–57
  • Kliem V, Johnson R J, Alpers C E, Yoshimura A, Couser W G, Koch K M, Floege J. Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6 nephrectomized rats. Kidney Int 1996; 49: 666–678
  • Coimbra T M, Janssen U, Gröne H J, Ostendorf T, Kunter U, Schmidt H, Brabant G, Floege J. Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes. Kidney Int 2000; 57: 167–182
  • Gröne H-J, Weber K, Gröne E, Helmcken U, Osborn M. Coexpression of keratin and vimentin in damaged and regenerating tubular epithelia of kidney. Am J Pathol 1987; 129: 1–8

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.