Effect of U-74500A, A 21-Aminosteroid on Renal Ischemia-Reperfusion Injury in Rats

References

• Bronphy D., Najarian J.S., Kjellstrand C.M. Acute tubular necrosis after renal transplantation. Transplantation 1980; 29: 245–254
   Google Scholar
• Weinberg J.M. The cell biology of ischemic renal injury. Kidney Int. 1991; 39: 476–483
   Google Scholar
• Paller M.S., Hoidal J.R., Ferris T.F. Oxygen free radicals in ischemic acute renal failure. J. Clin. Invest. 1984; 74: 1156–1164
   Google Scholar
• Weight S.C., Bell P.R.F., Nicholson M.L. Renal ischemia-reperfusion injury. Brit. J. Surg. 1984; 83: 162–170
   Google Scholar
• Linas S.L., Withemberg G., Repine J.E. O2 metabolites cause reperfusion injury after short but not prolonged renal ischemia. Am. J. Physiol. 1987; 253: F685–F692
   Google Scholar
• Hellberg P.O.A., Kallskog T.O.K. Neutrophil-mediated post ischemic tubular leakage in the rat kidney. Kidney Int. 1989; 36: 555–561
   Google Scholar
• Linas S.L., Withemberg G., Parsons P.E., Repine J.E. Ischemia increases neutrophil retention and worsens acute renal failure: role of oxygen metabolites and ICAM-1. Kidney Int. 1995; 48: 1584–1591
   Google Scholar
• Kehrer J.P. Free radicals as mediators of tissue injury and diseasex. Critic. Rev. Toxicol. 1993; 23: 21–48
   Google Scholar
• Gutteridge J.M. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin. Chem. 1995; 41: 1819–1826
   Google Scholar
• Stromski M.E., Cooper K., Thulin J., Gaudio K.M., Siegel N.J., Shulman R.J. Chemical and functional correlates of post-ischemic ATP levels. Proc. Natl. Acad. Sci. USA 1986; 83: 6142–6154
   Google Scholar
• Schrier R.W., Arnold P.E., Van Putten V.J., Burke T.J. Cellular calcium in ischemic acute renal failure: role of calcium entry blockers. Kidney Int. 1987; 32: 313–321
   Google Scholar
• Conger J.D., Robinette J.B., Schrier R.W. Smooth muscle calcium and endothelium-derived relaxing factor in the abnormal vascular responses of acute renal failure. J. Clin. Invest. 1988; 82: 532–537
   Google Scholar
• Kontogiannis J., Burns K.D. Role of AT1 angiotensin II receptors in renal ischemic injury. Am. J. Physiol. (Renal Physiol. 43) 1998; 274: F79–F90
   Google Scholar
• Lopez-Farre A., RamonyCajal S., Braquet P., Lopez-Novoa J.M. Platelet activating factor antagonists protect against post-ischemic renal failure in rats. J. Pharmacol. Exp. Ther. 1990; 253: 328–333
   Google Scholar
• Braughler J.M., Pregenzer J.F. The novel 21-aminosteroid inhibitors of lipid peroxidation: reaction with peroxyl and phenoxyl radicals. Free Radic. Biol. Med. 1989; 7: 125–130
   Google Scholar
• Hall E.D., McCall J.M., Means E.D. Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia, and subarachnoid hemorrhage. Adv. Pharmacol. 1994; 28: 221–268
   Google Scholar
• Du Z.Y., Hicks M., Spratt P., Mundy J.A., Macdonald P.S. Cardioprotective effects of pinacidil pretreatment and lazaroid (U74500A) preservation in isolated rat hearts after 12-hour hypothermic storage. Transplantation 1998; 66: 158–163
   Google Scholar
• Ryan T.P., Petry T.W. The effects of 21-aminosteroids on the redox status of iron in solution. Arch. Biochem. Biophys. 1993; 300: 699–704
   Google Scholar
• Ciuffi M., Gentilini G., Franchi-Micheli S., Zilletti L. Effect of 21-aminosteroid U74500A (pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(5,6-bis(diethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl, HCl (16 alpha)) on rat brain cortex lipid peroxidation induced “in vivo” by iron-carbohydrate. Biochem. Pharmacol. 1994; 47: 2181–2186
   Google Scholar
• Nishida T., Morita S., Miyamoto K., Masuda M., Tominaga R., Kawachi Y., Yasui H. The effect of lazaroid (U74500A), a novel inhibitor of lipid peroxidation, on 24-hour heart preservation. A study based on a working model using cross-circulated blood-perfused rabbit hearts. Transplantation 1996; 61: 194–199
   Google Scholar
• Ohkawa H., Oshishi N., Yagi K. Assay of lipid peroxidation in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 1979; 95: 331–358
   Google Scholar
• Brady H.R., Singer G.G. Acute renal failure. Lancet 1995; 346: 1533–1540
   Google Scholar
• Finn W.F., Chevalier R.L. Recovery from post-ischemic renal failure in the rat. Kidney Int. 1979; 16: 113–116
   Google Scholar
• Cronin R.E., Erickson A.M., De Torrente A. Norepinephrine induced acute renal failure. Kidney Int. 1978; 14: 187–191
   Google Scholar
• Pincemail J., Defraigne J.O., Fransen C., Bonnett P. Evidence for free radical formation during human kidney transplantation. Free Radic. Biol. Med. 1993; 15: 343–348
   Google Scholar
• Nishida T., Morita S., Masuda M., Tominaga R., Kawachi Y., Yasui H. Lazaroid U74500A is superior to U74006F in preserving rabbit heart for 24 hours. Ann. Thorac. Surg. 1998; 66: 1647–1652
   Google Scholar
• Ishizaki N., Zhu Y., Zhang S., Nemoto A., Kobayashi Y., Subbotin V., Starzl T.E., Todo S. Comparison of various lazaroid compounds for protection against ischemic liver injury. Transplantation 1997; 63: 202–208
   Google Scholar
• Hinzmann J.S., McKenna R.L., Pierson T.S., Hans F., Kezdy F.J., Epps D.E. Interactions of antioxidants with depth-dependent fluorescence quenchers and energy transfer probes in lipid bilayers. Chem. Phys. Lipids 1991; 62: 123–138
   Google Scholar
• Salvi A., Carrupt P., Tillement J., Testa B. Structural damage to proteins caused by free radicals: asessment, protection by antioxidants, and influence of protein binding (1). Biochem. Pharmacol. 2001; 61: 1237–1242
   Google Scholar
• Satyanarayana P.S.V., Singh D., Chopra K. Quercetin, a bioflavonoid, protects against oxidative stress related renal dysfunction by cyclosporine in rats. Methods Find. Exp. Clin. Pharmacol. 2001; 23: 175–181
   Google Scholar
• Galat J.A., Robinson A.V., Rhodes R.S. Oxygen free radical mediated renal dysfunction. J. Surg. Res. 1989; 46: 520–527
   Google Scholar
• Kim S.J., Lim Y.T., Kim B.S., Cho S.I., Woo J.S., Jung J.S., Kim Y.K. Mechanism of reduced GFR in rabbits with ischemic acute renal failure. Renal Fail. 2000; 22: 129–141
   Google Scholar
• Green C.J., Goiwer J.D., Healing G., Cotterill L.A., Fuller B.J., Simpkin S. The importance of iron, calcium and free radicals in reperfusion injury: an over view of studies in ischemic rabbit kidneys. Free Radic. Res. Commun. 1989; 7: 255–264
   Google Scholar
• Perico N., Benigni A., Zojam C., Delaini F., Remuzzi G. Functional significance of exaggerated renal thromboxane A2 synthesis induced by cyclosporine A. Am. J. Physiol. 1986; 251: F581–F587
   Google Scholar
• Yoo J., Schlondorff D., Neugartan J. Thromaboxane mediates the renal hemodynamic effect of platelet activating factor. J. Pharmacol. Exp. Ther. 1990; 253: 743–748
   Google Scholar
• Kon V., Huntley T.E., Fogo A. Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis. Transplantation 1995; 60: 89–95
   Google Scholar
• Shibouta Y., Suzuki N., Shino A., Matsumoto H., Terashita Z., Kondo K., Nishikawa K. Pathophysiological role of endothelin in acute renal failure. Life Sci. 1990; 46: 1611–1620
   Google Scholar
• Stanley J.J., Goldblum J.R., Franf T.S., Zelenock G.B., D'Alecy L.G. Attenuation of renal reperfusion injury in rats by the 21-aminosteroid U74600F. J. Vasc. Surg. 1993; 17: 685–689
   Google Scholar
• Paroni R., De Vechhi E., Lubatti L., Conti E., Beretta C., Rinaldi P., Galli Kienle M., Trazzi R. Influence of the 21-aminosteroid U734389F on ischemia-reperfusion in the rat. Eur. J. Pharmacol. 1995; 294: 737–742
   Google Scholar
• Gelb A.W., Henderson S.M., Zhang C. U-74006F, a 21-aminosteroid does not ameliorate feline focal cerebral ischemia. J. Neurosurg. Anaesthesiol. 1990; 2: 240–247
   Google Scholar
• Sutton A., Molitoris B.A. Mechanisms of cellular injury in ischemic acute renal failure. Semin. Nephrol. 1998; 18: 490–497
   Google Scholar