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CLINICAL STUDY

Plasma Homocysteine Levels in Indian Patients with Essential Hypertension and Their Siblings

, M.D., D.M., M.N.A.M.S., , &
Pages 195-201 | Published online: 07 Jul 2009

References

  • Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure. The fifth report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure. Arch. Intern. Med. 1993; 153: 154–183
  • Williams G.H. Hypertensive vascular diseases. Harrison's Principles of Internal Medicine, 14th Ed., A.S. Fauci, E. Braunwald, K. Isselbachler, J.B. Martin, D.L. Kasper, J.D. Wilson. Mc Graw Hill Inc., New York 1997; 1380–1394
  • Mccully K.S. Vascular pathology of homocysteinemia. Am. J. Pathol. 1969; 56: 111–128
  • Montalescot G., Ankri A., Chadefaux-Vekemans B., Blacher J., Philippe F., Drobinsky G. Plasma homocysteine and the extent of atherosclerosis in patients with coronary artery disease. Int. J. Cardiol. 1997; 60: 295–300
  • Aronow W.S., Ahn C. Association between plasm homocysteine and coronary artery disease. Am. J. Cardiol. 1997; 80: 1216–1218
  • Joubran R., Asmi M., Busajahn A., Vergopoulos A., Luft F.C., Jouma M. Homocysteine levels and coronary artery disease in Syria. J. Cardiovasc. Risk 1998; 5: 257–261
  • Perry I.J., Refsum H., Morris R.W., Ebrahim S.B., Ueland P.M., Shaper A.G. Prospective study of serum total homocysteine concentration and risk for stroke in middle aged British men. Lancet 1995; 346: 1395–1398
  • Lindgren A., Brattstrom L., Norrving B., Hultberg B., Andersson A., Johansson B. Plasma homocysteine in acute and convalescent phases after stroke. Stroke 1995; 26: 795–800
  • Verhoef P., Hennekens C.H., Malinow M.R., Kok F.J., Willett W.C., Stamfer K.J. A prospective study of plasma homocysteine and risk of ischemic stroke. Stroke 1994; 25: 1924–1930
  • Aronow W.S., Ahn C., Schoenfield M.R. Association between plasma homocysteine and extracranial carotid artery disease in older persons. Am. J. Cardiol. 1997; 79: 1432–1433
  • Sutton-Tyrell K., Bostom A., Sehlub J., Zeigle-Johnson C. High homocysteine levels are independently related to isolated systolic hypertension in older adults. Circulation 1997; 96: 1745–1749
  • Gupta R. Meta analysis of prevalence of hypertension in India. Indian Heart J. 1997; 49: 43–48
  • The sixth report of Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. Arch. Intern. Med. 1997; 197: 2401–2445
  • Araki A., Sako Y. Determination of free and total homocysteine in human plasma by high performance liquid chromatography with fluorescent detection. J. chromatog. 1987; 422: 43–52
  • Moustapha A., Robinson K. Homocysteine: an emerging age-related cardiovascular risk factor. Geriatrics 1999; 54: 49–63
  • Nygrad O., Vollset E., Refsum H., Stensvold I., Tverdal A., Nordrehaug J.E. Total plasma homocysteine and cardiovascular risk profile the Hordaland homocysteine study. JAMA 1995; 274: 1526–1533
  • Malinow M.R., Levenson J., Giral P., Nieto F.J., Razavian M., Segond P. Role of blood pressure, uric acid, and hemorheological parameters on homocysteine concentration atherosclerosis. 1995; 114: 175–183
  • Malinow M.R., Kang S.S., Taylor L.M. Prevalence of hyperhomocystinemia in patients with peripheral arterial occlusive disease. Circulation 1989; 79: 1180–1188
  • Araki A., Sako Y., Fukushima Y., Matsumoto M., Asada T., Kita T. Plasma sulfhydryl contained amino acid in patients with cerebral infarction and in hypertensive subjects. Atherosclerosis 1989; 79: 139–146
  • Kang S.S., Wong P.W.K., Cook H.Y., Norusis M., Messer J.V. Protein bound homocysteine a possible risk factor for coronary artery disease. J. Clin. Invest. 1986; 77: 1482–1486
  • Genest J.R., McNamara J.R., Salem D.N., Wilson P.W.F., Schaefer E.J., Malinow M.R. Plasma homocysteine levels in men with premature coronary artery disease. J. Am. Coll. Cardiol. 1990; 16: 1114–1120
  • Coull B.M., Malinow M.R., Beamer N., Sexton G., Nordt F., deGarmo P. Elevated plasma homocysteine concentration as a possible risk factor for stroke. Stroke 1990; 21: 572–576
  • Chacko K.A. Plasma homocysteine levels in patients with coronary heart disease. Indian Heart J. 1998; 50: 295–299
  • Smitha A.G., Lakshmi A.V., Krishna T.P., Kamala K. Fibrinogen and homocysteine levels in coronary artery disease. Indian Heart J. 1999; 51: 499–502
  • Deepa R., Velmurugan K., Saravanan G., Karkuzhali K., Dwarkanath V., Mohan V. Absence of association between serum homocysteine levels and coronary artery disease in south Indian males. Indian Heart J. 2001; 53: 44–47
  • Dejong S.C., Stehouwer C.D., Mackaay A.J. High prevalence of hyperhomocystinemia and asymptomatic vascular disease in siblings of young patients with vascular disease and hyperhomocystinemia. Arterioscler. Thormb. Vasc. Biol. 1997; 17: 2655–2662
  • Greenlund K.J., Srinivasan S.R., Xu J.H., Dalferes E., Jr., Myers L., Pickoff A. Plasma homocysteine distribution and its association with parental history of coronary artery disease in black and while children; the Bogalusa Heart study. Circulation 1999; 99: 2144–2149
  • Vermeulen E.G., Stehouwer C.D., Twisk J.W. Effect of homocysteine lowering treatment with folic acid plus vitamin B6 on progression of subclinical atherosclerosis: a randomized placebo controlled trial. Lancet 2000; 355: 517–522
  • Tonstad S., Refsum H., Ueland P.M. Association between plasma total homocysteine and parental history of cardiovascular disease in children. Circulation 1997; 96: 1803–1808u
  • Jourdeuil Rahmani D., Rolland P.H., Garcon D. Homocysteine induces synthesis and secretion and serine elastases in isolated smooth muscle cells from human normal arteries. Ir. J. Med. Sci. 1995; 164(Suppl. 15), Abstract
  • Charpio P., Augier T., Chareyre C., Rolland P.H., Garcon D. Hyperhomocystinemia-induced vascular elastic alterations in the mini pig: biochemical and morphometric analysis of elastin. Ir. J. Med. Sci. 1995; 164(Suppl. 15), Abstract
  • Celermajer D.S., Sorensen K., Ryalls M., Robinson J., Thomas O., Leonard J.V., Deanfield J.E. Impaired endothelial function occurs in the systemic arteries of children with homozygous homocystinuria but not in their heterozygous patients. J. Am. Coll. Cardiol. 1993; 22: 854–858
  • Tawakol A., Omland T., Gerhard M., Wu J.T., Creager M.A. Hyperhomocystinemia in association with impaired endothelium dependent vasodilatation in humans. Circulation 1997; 95: 1119–1121

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