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Research Article

Granulation of Acetaminophen by a Rotating Fluidized-Bed Granulator

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Pages 141-151 | Received 27 Jan 1998, Accepted 04 Aug 1999, Published online: 19 Apr 2000

REFERENCES

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  • Vogel S. H. Directly Compressible Acetaminophen Granulation; Sodium Carboxymethyl Cellulose, Binder, Lubricant. U.S. Patent 4, 439, 453, 1984
  • Salpekar A. M., Freebersyser S. R., Robinson D. A. N-acetyl-p-aminophenol Compositions Coating Partially Gelatinized Starch and Method for Preparing Same. U.S. Patent 4, 757, 090, 1988
  • Patel N. K., Poola N. R., Babar A., Plakogiannis F. M. Fluidized-bed agglomeration of acetaminophen; direct compression of tablets and physiologic availability. Drug Dev. Ind. Pharm. 1989; 15(1)175
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  • Schaefer T., Woerts O. Control of fluidized bed granulation. II. Estimation of droplet size of atomized binder solution. Arch. Pharm. Chem. Sci. Ed. 1977; 5: 178–193

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