Ocular permeation and inhibition of retinal inflammation: an examination of data and expert opinion on the clinical utility of nepafenac

References

• Flach AJ. Topical nonsteroidal antiinflammatory drugs in ophthalmology. Int Ophthalmol Clin 2002;42:1–11
   PubMedGoogle Scholar
• Samiy N, Foster CS. The role of nonsteroidal antiinflammatory drugs in ocular inflammation. Int Ophthalmol Clin 1996;36:195–206
   PubMedGoogle Scholar
• Lane SS, Modi SS, Holland EJ, et al. Nepafenac ophthalmic suspension 0.1% before and after surgery for postoperative anterior segment inflammation. Paper presented at: American Society of Cataract and Refractive Surgery, April 18, 2005, Washington, DC
   Google Scholar
• Stewart WC, Stewart R, Maxwell WA, et al. Preoperative and postoperative clinical evaluation of nepafenac 0.1% ophthalmic suspension for postcataract inflammation. Paper presented at: American Society of Cataract and Refractive Surgery, April 18, 2005, Washington, DC
   Google Scholar
• Donnenfeld ED, Holland EJ, Stewart R, et al. Topical xibrom 0.1% investigational NSAID to decrease inflammation after cataract surgery. Paper presented at: American Society of Cataract and Refractive Surgery, April 18, 2005, Washington, DC
   Google Scholar
• Heier J, Cheetham JK, Degryse R, et al. Ketorolac tromethamine 0.5% ophthalmic solution in the treatment of moderate to severe ocular inflammation after cataract surgery: a randomized, vehicle-controlled clinical trial. Am J Ophthalmol 1999;127: 253–9
   Google Scholar
• Yee RW, Ketorolac Radial Keratotomy Study Group. Analgesic efficacy and safety of nonpreserved ketorolac ophthalmic solution following radial keratotomy. Am J Ophthalmol 1998;125:472–80
   Google Scholar
• Eiferman RA, Hoffman RS, Sher NA. Topical diclofenac reduced pain following photorefractive keratectomy. Arch Ophthalmol 1993;111:1022
   Google Scholar
• Szerenyi K, Sorken K, Garbus JJ, et al. Decrease in normal human corneal sensitivity with topical diclofenac sodium. Am J Ophthalmol 1994;118:312–5
   PubMed Web of Science ®Google Scholar
• Price MO, Price FW. Efficacy of topical ketorolac tromethamine 0.4% for control of pain or discomfort associated with cataract surgery. Curr Med Res Opin 2004;20:2015–9
   Google Scholar
• Jampol LM. Pharmacologic therapy of aphakic cystoid macular edema: a review. Ophthalmology 1982;89:891–7
   PubMed Web of Science ®Google Scholar
• Gamache DA, Graff G, Brady MT, et al. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma-induced ocular inflammation: I. Assessment of anti- inflammatory efficacy. Inflammation 2000;24:357–70
   Google Scholar
• Ke TL, Graff G, Spellman JM, et al. Nepafenac, a unique nonsteroidal prodrug with potential utility in the treatment of trauma-induced ocular inflammation: II. In vitro bioactivation and permeation of external ocular barriers. Inflammation 2000;24:371–84
   PubMed Web of Science ®Google Scholar
• Kapin MA, Yanni JM, Brady MT, et al. Inflammation-mediated retinal edema in the rabbit is inhibited by topical nepafenac. Inflammation 2003;27;281–91
   PubMed Web of Science ®Google Scholar
• O’Brien TP. Emerging guidelines for use of NSAID therapy to optimized cataract surgery patient care. Curr Med Res Opin 2005;21:1131–7
   PubMed Web of Science ®Google Scholar
• Miyake K, Masuda K, Shirato S, et al. Comparison of diclofenac and fluorometholone in preventing cystoid macular edema after small incision cataract surgery: a multicentered prospective trial. Jpn J Ophthalmol 2000;44:58–67
   PubMed Web of Science ®Google Scholar
• Bringmann A, Reichenbach A, Wiedemann P. Pathomechanisms of cystoid macular edema. Ophthalmic Res 2004;36;241–9
   Google Scholar
• McColgin AZ, Raizman MB. Efficacy of topical Voltaren in reducing the incidence of post operative cystoid macular edema. Invest Ophthmol Vis Sci 1999;40:S289
   PubMedGoogle Scholar
• Sivaprasad S, Bunce C, Patel N. Non-steroidal anti-inflammatory agents for treating cystoid macular oedema following cataract surgery. Cochrane Database Syst Rev 2005;1:CD004239
   Google Scholar
• Solomon LD. Efficacy of topical flurbiprofen and indomethacin in preventing pseudophakic cystoid macular edema [Flurbiprofen-CME Study Group]. J Cataract Refract Surg 1995;21:73–81
   PubMed Web of Science ®Google Scholar
• Ginsburg AP, Cheetham JK, DeGryse RE, et al. Effects of flurbiprofen and indomethacin on acute cystoid macular edema after cataract surgery: functional vision and contrast sensitivity. J Cataract Refract Surg 1995;21:82–92
   PubMed Web of Science ®Google Scholar
• Miyake K, Sakamura S, Miura H. Long-term follow-up study on prevention of aphakic cystoid macular oedema by topical indomethacin. Brit J Ophthalmol 1980;64:324–8
   Google Scholar
• Flach AJ, Stegman RC, Graham J, et al. Prophylaxis of aphakic cystoid macular edema without corticosteroids: a paired-comparison, placebo-controlled double-masked study. Ophthalmology 1990;97:1253–8
   PubMed Web of Science ®Google Scholar
• Rome LH, Lands WE. Structural requirements for time- dependent inhibition of prostaglandin biosynthesis by antiinflammatory drugs. Proc Natl Acad Sci USA 1975;72:4863–5
   PubMed Web of Science ®Google Scholar
• Walsh DA, Sancilio LF, Reese DL. Aroyl- and arylisoquinoline- acetic acids as antiinflammatory agents. J Med Chem 1978;21:582–5
   Google Scholar
• Walsh DA, Moran HW, Shamblee DA, et al. Anti-inflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino- 3-benzoylphenylacetic acid and analogues. J Med Chem 1984;27: 1379–88
   Google Scholar
• Walsh DA, Moran HW, Shamblee DA, et al. Anti-inflammatory agents. 4. Syntheses and biological evaluation of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid and 2-amino-3-(4-chloro-benzoyl) benzeneacetic acid. J Med Chem 1990;33: 2296–304
   Google Scholar
• Kulkarni P S. The role of endogenous eicosanoids in rabbit- intraocular inflammation. J Ocul Pharmacol 1991;7:227–41
   PubMedGoogle Scholar
• Srinivasan BD, Kulkarni PS. Inhibitors of the arachidonic acid cascade in the management of ocular inflammation. Prog Clin Biol Res 1989;312:229–49
   PubMedGoogle Scholar
• Mitchell JA, Akarasereenont P, Thiemermann C, et al. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc Natl Acad Sci USA 1993;90:11693–7
   PubMed Web of Science ®Google Scholar