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Original Article

Pharmacokinetics and pharmacodynamics of a known active PPI with a novel Dual Delayed Release technology, dexlansoprazole MR: a combined analysis of randomized controlled clinical trials

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Pages 627-638 | Accepted 16 Dec 2008, Published online: 26 Jan 2009

References

  • Sachs G, Shin JM, Briving C, et al. The pharmacology of the gastric acid pump: the H+,K+ ATPase. Annu Rev Pharmacol Toxicol 1995;35:277-305
  • Chiba N, De Gara CJ, Wilkinson JM, et al. Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis. Gastroenterology 1997;112:1798-810
  • van Pinxteren B, Numans ME, Bonis PA, et al.Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev 2006;3: CD002095
  • Fries JF, Murtagh KN, Bennett M, et al. The rise and decline of nonsteroidal antiinflammatory drug-associated gastropathy in rheumatoid arthritis. Arthritis Rheum 2004;50:2433-40
  • Tytgat GN. Shortcomings of the first-generation proton pump inhibitors. Eur J Gastroenterol Hepatol 2001;13:S29-33
  • Fass R. Proton-pump inhibitor therapy in patients with gastro-oesophageal reflux disease: putative mechanisms of failure. Drugs 2007;67:1521-30
  • Katsuki H, Yagi H, Arimori K, et al. Determination of R(+)- and S(-)-lansoprazole using chiral stationary-phase liquid chromatography and their enantioselective pharmacokinetics in humans. Pharm Res 1996;13:611-15
  • Gibaldi M, Perrier D. Kinetics of pharmacologic response. Pharmacokinetics, 2nd edn. New York and Basel: Marcel Dekker, 1982:221-65
  • Gabrielsson J, Weiner D. Pharmacodynamic concepts. Pharmacokinetic Data Analysis: Concepts and Applications. Swedish Pharmaceutical Press, 2nd edn. Stockholm, 1997:171-248
  • Bell NJV, Burger D, Howden CW, et al. Appropriate acid suppression for the management of gastro-oesophageal reflux disease. Digestion 1992;51:59-67
  • Yuan Y, Thabane M, Hunt RH. Does suppression of 24-hour intragastric pH predict healing of erosive esophagitis with antisecretory treatment: a meta-analysis. Gastroenterology 2007;132:A489. Abstract
  • Katz PO, Ginsberg GG, Hoyle PE, et al. Relationship between intragastric acid control and healing status in the treatment of moderate to severe erosive oesophagitis. Aliment Pharmacol Ther 2007;25:617-28
  • Andersson T, Rohss K, Bredberg E, et al. Pharmacokinetics and pharmacodynamics of esomeprazole, the S-isomer of omeprazole. Aliment Pharmacol Ther 2001;15:1563-9

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