255
Views
7
CrossRef citations to date
0
Altmetric
Brief Report

Single-dose pharmacokinetic study of rapidly dispersing diclofenac potassium formulations in healthy volunteers

, , &
Pages 2423-2428 | Accepted 02 Jul 2009, Published online: 10 Aug 2009

References

  • Top 200 generic drugs by units in 2006. Drug Topics. Woodland Hills, CA: Modern Medicine.com, a service of Advanstar Communications, Inc., 2008. Available at www.drugtopics.com/drugtopics/data/articlestandard//drugtopics/092007/407652/article.pdf [Last accessed 12 February 2008]
  • Label and approval history for Voltaren. Drugs@FDA. Washington, DC: FDA/Center for Drug Evaluation and Research, 2008. Available at www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Overview& DrugName=VOLTAREN [Last accessed 13 February 2008]
  • Graham DJ, Campen D, Hui R, et al. Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. Lancet 2005;365:475-81
  • Hippisley-Cox J, Coupland C. Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case–control analysis. BMJ 2005;330:1366
  • Mitchell JA, Warner TD. Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy. Br J Pharmacol 1999;128:1121-32
  • Moore N. Diclofenac potassium 12.5 mg tablets for mild to moderate pain and fever: a review of its pharmacology, clinical efficacy and safety. Clin Drug Investig 2007;27:163-95
  • Bakshi R, Frenkel G, Dietlein G, et al. A placebo-controlled comparative evaluation of diclofenac dispersible versus ibuprofen in postoperative pain after third molar surgery. J Clin Pharmacol 1994;34:225-30
  • Breivik EK, Barkvoll P, Skovlund E. Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study. Clin Pharmacol Ther 1999;66:625-35
  • Hersh EV, Levin LM, Adamson D, et al. Dose-ranging analgesic study of Prosorb diclofenac potassium in postsurgical dental pain. Clin Ther 2004;26:1215-27
  • Matthews RW, Scully CM, Levers BG. The efficacy of diclofenac sodium (Voltarol) with and without paracetamol in the control of post-surgical dental pain. Br Dent J 1984;157:357-9
  • Bamber MJ, Tweedie IE, Breeze C, et al. Premedication with controlled release diclofenac sodium reduces post-operative pain after minor gynaecological surgery. Eur J Anaesthesiol 1997;14:421-7
  • McEvoy A, Livingstone JI, Cahill CJ. Comparison of diclofenac sodium and morphine sulphate for postoperative analgesia after day case inguinal hernia surgery. Ann R Coll Surg Engl 1996;78:363-6
  • Hinz B, Chevts J, Renner B, et al. Bioavailability of diclofenac potassium at low doses. Br J Clin Pharmacol 2005;59:80-4
  • Lötsch J, Kettenmann B, Renner B, et al. Population pharmacokinetics of fast release -oral diclofenac in healthy volunteers: relation to pharmacodynamics in an experimental pain model. Pharm Res 2000;17:77-84
  • Macia MA, Frias J, Carcas AJ, et al. Comparative bioavailability of a dispersible formulation of diclofenac and finding of double plasma peaks. Int J Clin Pharmacol Ther 1995;33:333-9
  • Reiner V, Reiner A, Reiner G, et al. Increased absorption rate of diclofenac from fast acting formulations containing its potassium salt. Arzneimittelforschung 2001;51:885-90
  • Riad LE, Sawchuk RJ, McAlary MM, et al. Effect of food on the multiple-peak behavior after a single oral dose of diclofenac sodium slow-release tablet in humans. Am J Ther 1995;2:237-42
  • Terhaag B, Hoffmann A, Barkworth M, et al. Bioavailability of a new effervescent tablet of diclofenac. Int J Clin Pharmacol Ther 2000;38:546-51
  • Ceppi Monti N, Gazzaniga A, Gianesello V, et al. Activity and pharmacokinetics of a new oral dosage form of soluble ibuprofen. Arzneimittelforschung 1992;42:556-9
  • Laska EM, Sunshine A, Marrero I, et al. The correlation between blood levels of ibuprofen and clinical analgesic response. Clin Pharmacol Ther 1986;40:1-7
  • Seymour RA, Hawkesford JE, Weldon M, et al. An evaluation of different ibuprofen preparations in the control of postoperative pain after third molar surgery. Br J Clin Pharmacol 1991;31:83-7
  • Mojaverian P, Rocci ML Jr, Conner DP, et al. Effect of food on the absorption of enteric-coated aspirin: correlation with gastric residence time. Clin Pharmacol Ther 1987;41:11-17
  • Sanchez J, Martinez L, Garcia-Barbal J, et al. The influence of gastric emptying on droxicam pharmacokinetics. J Clin Pharmacol 1989;29:739-45
  • Welling PG. Interactions affecting drug absorption. Clin Pharmacokinet 1984;9:404-34
  • Vidon N, Pfeiffer A, Godbillon J, et al. Evaluation of the gastric absorption and emptying of drugs under various pH conditions using a simple intubation method: application to diclofenac. Br J Clin Pharmacol 1989;28:121-4
  • Marzo A, Dal Bo L, Verga F, et al. Pharmacokinetics of diclofenac after oral administration of its potassium salt in sachet and tablet formulations. Arzneimittelforschung 2000;50:43-7
  • Silva LC, Simoes IG, Lerner FE, et al. Comparative bioavailability of two different diclofenac formulations in healthy volunteers. Arzneimittelforschung 1999;49:920-4
  • Cataflam (package insert). East Hanover, NJ: Novartis Pharmaceuticals Corporation, July 2005

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.