664
Views
37
CrossRef citations to date
0
Altmetric
Original Article

Cost-effectiveness analysis of the use of a high-intensity statin compared to a low-intensity statin in the management of patients with familial hypercholesterolaemia

, , , , , & show all
Pages 529-536 | Accepted 18 Nov 2009, Published online: 17 Dec 2009

References

  • Austin MA, Hutter CM, Zimmern RL, et al. Genetic causes of monogenic heterozygous familial hypercholesterolemia: a HuGE prevalence review. Am J Epidemiol 2004;160:407-20
  • Humphries SE, Whittall RA, Hubbart CS, et al. Genetic causes of familial hypercholesterolaemia in patients in the UK: relation to plasma lipid levels and coronary heart disease risk (letter). J Med Genet 2006;43:943-9
  • Scientific Steering Committee on behalf of the Simon Broome Register Group. Mortality in treated heterozygous familial hypercholesterolaemia: implications for clinical management. Atherosclerosis 1999;142:105-12
  • DeMott K, Nherera L, Shaw EJ, et al. Clinical guidelines and evidence review for familial hypercholesterolaemia: the identification and management of adults and children with familial hypercholesterolaemia. London: National Collaborating Centre for Primary Care and Royal College of General Practitioners, 2008
  • Metcalfe S. Technology Assessment Report No. 2. Costs and benefits of simvastatin 40 mg vs fluvastatin 80 mg for patients with familial hyperlipidaemia. Technology Assessment Reports. Wellington, NZ: PHARMAC, 1997
  • Ara R, Tumur I, Pandor A, et al. Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation. Health Technol Assess 2008;12:1-212
  • LaRosa JC, Grundy SM, Waters DD, et al. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med 2005;352:1425-35
  • Pedersen TR, Faergeman O, Kastelein JJP, et al. High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction. The IDEAL study: a randomized controlled trial. JAMA 2005;294:2437-45
  • Cannon CP, Braunwald E, McCabe CH, et al. Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N Engl J Med 2004;350:1495-504
  • de Lemos JA, Blazing MA, Wiviott SD, et al. Early intensive vs a delayed conservative simvastatin strategy in patients with acute coronary syndromes phase Z of the A to Z trial. JAMA 2004;292:1307-16
  • Smilde TJ, van Wissen S, Wollersheim H, et al. Effect of aggressive versus conventional lipid lowering on atherosclerosis progression in familial hypercholesterolaemia (ASAP): a prospective randomized, double-blind trial. Lancet 2001;357:577-81
  • National Institute for Health and Clinical Excellence. Statins for the prevention of cardiovascular events. Technology Appraisal. London: National Institute for Health and Clinical Excellence, 2006. Available from: http://www.nice.org.uk/Guidance/TA94 [Last accessed 30 October 2009]
  • Government Actuary’s Department. Interim Life Tables: Government Actuary’s Department, 2006 Available from: http://www.gad.gov.uk/Demography_Data/Life_Tables/Interim_life_tables.asp. [Last accessed 30 October 2009]
  • Department of Health. NHS Costing Manual 2008/9. Reference Costs 2008. Dept of Health 2008 Available from http://www.dh.gov.uk/PolicyAndGuidance/OrganisationPolicy/FinanceAndPlanning/NHSCostingManual/fs/en. [Last accessed 30 October 2009]
  • NHS Business Services Authority. Prescription Pricing Division. NHS Electronic Drug Tariff, 2008
  • Prescott-Clarke P, Primatesta P. Health Survey for England ‘96: The Stationery Office, 1997
  • Cholesterol Treatment Trialists’ Collaborators. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 2005;366:1267-78
  • Catapano A, Brady WE, King TR, et al. Lipid altering-efficacy of ezetimibe co-administered with simvastatin compared with rosuvastatin: a meta-analysis of pooled data from 14 clinical trials. Curr Med Res Opin 2005;21:1123-30
  • Packham C, Gray D, Silcocks P, et al. Identifying the risk of death following hospital discharge in patients admitted with a suspected acute myocardial infarction in whom the diagnosis is not confirmed. Eur Heart J 2000;21:213-19
  • Versmissen J, Oosterveer DM, Yazdanapanah M, et al. Efficacy of statins in familial hypercholesterolaemia: a long term cohort study. Br Med J 2008;337: a2423, doi:10.1136/bmj.a2423
  • Neil A, Humphries SE. Statins and familial hypercholesterolaemia. BMJ 2009;338: a3041, doi: 10.1136/bmj.a3041
  • Law MR, Wald NJ, Rudnicka AR. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. Br Med J 2003;326:1423-9
  • Chan PS, Nallamothu BK, Gurm HS, et al. Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery disease. Circulation 2007;115:2398-2409
  • National Institute for Health and Clinical Excellence. Hypertension: Management of hypertension in adults in primary care. CG34. London: National Institute for Health and Clinical Excellence, 2006. Available from http://guidance.nice.org.uk/CG34.[Last accessed 30 October 2009]
  • Karnon J, Akehurst R, Brennan A, et al. Modelling the long term cost effectiveness of clopidogrel for the secondary prevention of occlusive vascular events in the UK. Curr Med Res Opin 2005;21:101-12
  • Mason JM, Freemantle N, Gibson JM, et al. Specialist nurse-led clinics to improve control of hypertension and hyperlipidemia in diabetes: economic analysis of the SPLINT trial. Diabetes Care 2005;28:40-6
  • Davies A, Hutton J, O’Donnell J, et al. Cost-effectiveness of rosuvastatin, atorvastatin, simvastatin, pravastatin and fluvastatin for the primary prevention of CHD in the UK. Br J Cardiol 2006;13:196-202
  • Yock CA, Boothroyd DB, Owens DK, et al. Cost-effectiveness of bypass surgery versus stenting in patients with multivessel coronary artery disease. Am J Med 2003;115:382-9

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.