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Editorial

The challenge of predicting macular degeneration

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Pages 1745-1748 | Accepted 04 Jul 2011, Published online: 22 Jul 2011

References

  • Chakravarthy U, Evans J, Rosenfeld PJ. Age related macular degeneration. BMJ 2010;340:c981
  • Access Economics. The global economic cost of visual impairment. 2010. Available at: http://www.amdalliance.org/user_files/documents/Global%20cost%20of%20VI_FINAL%20report.pdf [Last accessed 14 February 2011]
  • Tong Y, Liao J, Zhang Y, et al. LOC387715/HTRA1 gene polymorphisms and susceptibility to age-related macular degeneration: a HuGE review and meta-analysis. Mol Vis 2010;16:1958-81
  • Hageman GS, Anderson DH, Johnson LV, et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration. PNAS 2005;102:7227-32
  • Schaumberg DA, Hankinson SE, Guo Q, et al. A prospective study of 2 major age-related macular degeneration susceptibility alleles and interactions with modifiable risk factors. Arch Ophthalmol 2007;125:55-62
  • Chen Y, Zeng J, Zhao C, et al. Assessing susceptibility to age-related macular degeneration with genetic markers and environmental factors. Arch Ophthalmol 2011;129:344-51
  • Seddon JM, Francis PJ, George S, et al. Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration. JAMA 2007;297:1793-800
  • Welsh MJ, Ramsey BW, Accurso F, et al. The metabolic and molecular bases of inherited diseases. Cystic fibrosis. In: Scriver C, Volgestein B, Beaudet AL, Sly WS, Valle D (eds.) New York: McGraw-Hill, 2001:5121-88
  • Kraft P, Hunter DJ. Genetic risk prediction – are we there yet? N Engl J Med 2009;360:1701-3
  • Hughes AE, Orr N, Patterson C, et al. Neovascular age-related macular degeneration risk based on CFH, LOC387715/HTRA1, and smoking. Invest Ophthalmol Vis Sci 2011;52:4694-702
  • Janssens AC, van Duijn CM. Genome-based prediction of common diseases: advances and prospects. Hum Mol Genet 2008;17:R166-73
  • Curcio CA. Photoreceptor topography in aging and age-related maculopathy. Eye 2001;15:376-83
  • Guymer R, Luthert P, Bird AC. Changes in Bruch's membrane and related structures with age. Prog Ret Eye Res 1999;18:59-90
  • Feigl B. Age-related maculopathy: linking aetiology and pathophysiological changes to the ischaemia hypothesis. Prog Ret Eye Res 2009;28:63-86
  • Wooten BR, Hammond BR Jr, Land RI, et al. A practical method for measuring macular pigment optical density. Invest Ophthalmol Vis Sci 1999;40:2481-9
  • Seddon JM, Ajani UA, Sperduto RD, et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case–Control Study Group. JAMA 1994;272:1413-20
  • SanGiovanni JP, Chew EY, Clemons TE, et al. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case–control study: AREDS Report No. 22. Arch Ophthalmol 2007;125:1225-32
  • Dietzel M, Zeimer M, Heimes B, et al. Determinants of macular pigment optical density and its relation to age-related maculopathy: results from the muenster aging and retina study (Mars). Invest Ophthalmol Vis Sci 2011;52:3452-7
  • Beatty S, van Kuijk FJ, Chakravarthy U. Macular pigment and age-related macular degeneration: longitudinal data and better techniques of measurement are needed. Invest Ophthalmol Vis Sci 2008;49:843-5
  • Hogg RE, Dimitrov PN, Dirani M, et al. Gene–environment interactions and aging visual function: a classical twin study. Ophthalmology 2009;116:263-9
  • Owsley C, Jackson GR, White M, et al. Delays in rod-mediated dark-adaptation in early age-related maculopathy. Ophthalmology 2001;108:1196-202
  • Dimitrov PN, Guymer RH, Zele AJ, et al. Measuring rod and cone dynamics in age-related maculopathy. Invest Ophthalmol Vis Sci 2008;49:55-65
  • Phipps JA, Dang TM, Vingrys AJ, et al. Flicker perimetry losses in age-related macular degeneration. Invest Ophthalmol Vis Sci 2004;45:3355-60
  • Feigl B, Cao D, Morris CP, Zele AJ. Persons with age-related maculopathy risk genotypes and clinically normal eyes have reduced mesopic vision. Invest Ophthalmol Vis Sci 2011;52:1145-50
  • Grunwald JE, Hariprasad SM, DuPont J, et al. Foveal choroidal blood flow in age-related macular degeneration (AMD). Invest Ophthalmol Vis Sci 1998;39:385-90
  • Chen JC, Fitzke FW, Pauleikhoff D, et al. Functional loss in age-related Bruch's membrane change with choroidal perfusion defect. Invest Ophthalmol Vis Sci 1992;33:334-40
  • Stefansson E, Geirsdottir A, Sigurdsson H. Metabolic physiology in age related macular degeneration. Prog Retin Eye Res 2011;30:72-80
  • Kloeckener-Gruissem B, Barthelmes D, Labs S, et al. Genetic association with response to intravitreal ranibizumab (Lucentis) in neovascular AMD patients. Invest Ophthalmol Vis Sci 2011;52:4694-702

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