294
Views
14
CrossRef citations to date
0
Altmetric
Endocrinology: Original Article

Effects of skin washing on systemic absorption of testosterone in hypogonadal males after administration of 1.62% testosterone gel

, , , , , & show all
Pages 271-279 | Accepted 19 Dec 2011, Published online: 17 Jan 2012

References

  • Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. N Engl J Med 2004;350:482-92 [PubMed: 14749457]
  • Wang C, Swerdloff RS, Iranmanesh A, et al. Effects of transdermal testosterone gel on bone turnover markers and bone mineral density in hypogonadal men. Clin Endocrinol (Oxf) 2001;54:739-50 [PubMed: 11422108]
  • Davidson JM, Camargo CA, Smith ER. Effects of androgen on sexual behavior in hypogonadal men. J Clin Endocrinol Metab 1979;48:955-8 [PubMed: 447801]
  • Kwan M, Greenleaf WJ, Mann J, et al. The nature of androgen action on male sexuality: a combined laboratory-self-report study on hypogonadal men. J Clin Endocrinol Metab 1983;57:557-62 [PubMed: 6874890]
  • O'Carroll R, Shapiro C, Bancroft J. Androgens, behavior and nocturnal erection in hypogonadal men: the effects of varying the replacement dose. Clin Endocrinol (Oxf) 1985;23:527-38 [PubMed: 3910302]
  • Skakkebaek NE, Bancroft J, Davidson DW, et al. Androgen replacement with oral testosterone undecanoate in hypogonadal men: a double blind controlled study. Clin Endocrinol (Oxf) 1981;14:49-61 [PubMed: 7014044]
  • Morley JE, Perry HM, 3rd, Kaiser FE, et al. Effects of testosterone replacement therapy in old hypogonadal males: a preliminary study. J Am Geriatr Soc 1993;41:149-52 [PubMed: 8426037]
  • Wang C, Cunningham G, Dobs A, et al. Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. J Clin Endocrinol Metab 2004;89:2085-98 [PubMed: 15126525]
  • Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2006;91:1995-2010 [PubMed: 16720669]
  • Tenover JL. Male hormone replacement therapy including “andropause”. Endocrinol Metab Clin North Am 1998;27:969-87 [PubMed: 9922917]
  • IMS National Prescription Audit. National Prescription Audit, June 2000–October 2009. Plymouth Meeting, PA: IMS Health Inc., 2010
  • McNicholas TA, Dean JD, Mulder H, et al. A novel testosterone gel formulation normalizes androgen levels in hypogonadal men, with improvements in body composition and sexual function. BJU Int 2003;91:69-74 [PubMed: 12614254]
  • Steidle C, Schwartz S, Jacoby K, et al. AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function. J Clin Endocrinol Metab 2003;88:2673-81 [PubMed: 12788872]
  • Swerdloff RS, Wang C, Cunningham G, et al. Long-term pharmacokinetics of transdermal testosterone gel in hypogonadal men. J Clin Endocrinol Metab 2000;85:4500-10 [PubMed: 11134099]
  • Asnani S, Cefalu CA, Naval-Srinivas RM. Testosterone replacement in the elderly: a clinical approach. Ann Long-Term Care 2003;11:44-50 [PubMed: n/a]
  • Brawer MK. Testosterone replacement in men with andropause: an overview. Rev Urol 2004;6(Suppl 6):S9-15 [PubMed: 16985914]
  • Hayes FJ. Androgen replacement in the male: recent studies. Curr Opin Endocrinol Diabetes 2001;8:301-6
  • Oettel M. The endocrine pharmacology of testosterone therapy in men. Naturwissenschaften 2004;91:66-76 [PubMed: 14991143]
  • Bhowmick SK, Ricke T, Rettig KR. Sexual precocity in a 16-month-old-boy induced by indirect topical exposure to testosterone. Clin Pediatr (Phila) 2007;46:540-3 [PubMed: 17579107]
  • Brachet C, Vermeulen J, Heinrichs C. Children's virilization and the use of a testosterone gel by their fathers. Eur J Pediatr 2005;164:646-7 [PubMed: 16025298]
  • de Ronde W. Hyperandrogenism after transfer of topical testosterone gel: case report and review of published and unpublished studies. Hum Reprod 2009;24:425-8 [PubMed: 18948313]
  • Kunz GJ, Klein KO, Clemons RD, et al. Virilization of young children after topical androgen use by their parents. Pediatrics 2004;114:282-4 [PubMed: 15231947]
  • Merhi ZO, Santoro N. Postmenopausal virilization after spousal use of topical androgens. Fertil Steril 2007;87:976.e13-15 [PubMed: 17254577]
  • Yu YM, Punyasavatsu N, Elder D, et al. Sexual development in a two-year-old boy induced by topical exposure to testosterone. Pediatrics 1999;104:e23 [PubMed: 10429141]
  • de Ronde W, Vogel S, Bui HN, et al. Reduction in 24-hour plasma testosterone levels in subjects who showered 15 or 30 minutes after application of testosterone gel. Pharmacotherapy 2011;31:248-52 [PubMed: 21361734]
  • AndroGel® (testosterone gel) 1.62% [prescribing information]. North Chicago, IL: Abbott Laboratories, 2011
  • Kaufman JM, Miller MG, Garwin JL, et al. Efficacy and safety study of 1.62% testosterone gel for the treatment of hypogonadal men. J Sex Med 2011;8:2079-89 [PubMed: 21492400]
  • Miller J, Britto M, Fitzpatrick S, et al. Pharmacokinetics and relative bioavailability of absorbed testosterone after administration of a 1.62% testosterone gel to different application sites in men with hypogonadism. Endocr Pract 2011;17:574-83 [PubMed: 21454244]
  • Delanoe D, Fougeyrollas B, Meyer L, et al. Androgenisation of female partners of men on medroxyprogesterone acetate/percutaneous testosterone contraception. Lancet 1984;1:276 [PubMed: 6143012]
  • Mazer N, Fisher D, Fischer J, et al. Transfer of transdermally applied testosterone to clothing: a comparison of a testosterone patch versus a testosterone gel. J Sex Med 2005;2:227-34 [PubMed: 16422890]
  • Rolf C, Knie U, Lemmitz G, et al. Interpersonal testosterone transfer after topical application of a newly developed testosterone gel preparation. Clin Endocrinol (Oxf) 2002;56:637-41 [PubMed: 12030915]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.