448
Views
11
CrossRef citations to date
0
Altmetric
Endocrinology: Brief report

Skin reactions in a phase 3 study of a testosterone topical solution applied to the axilla in hypogonadal men

, &
Pages 761-766 | Accepted 27 Mar 2012, Published online: 18 Apr 2012

References

  • Hay JB, Hodgins MB. Distribution of androgen metabolizing enzymes in isolated tissues of human forehead and axillary skin. J Endocrinol 1978;79:29-39
  • Montagna W, Parakkal PF. The Structure and Function of Skin. 3rd edn. New York: Academic Press, 1974
  • Draize JH, Woodard G, Calvery HO. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther 1944;82:377-90
  • Farage MA, Maibach HI, Andersen KE, et al. Historical perspective on the use of visual grading scales in evaluating skin irritation and sensitization. Contact Dermatitis 2011;65:65-75
  • Wang C, Ilani N, Arver S, et al. Efficacy and safety of the 2% formulation of testosterone topical solution applied to the axillae in androgen-deficient men. Clin Endocrinol (Oxf) 2011;75:836-43
  • Olsen CT. Evaluation of the dermal irritancy of chemicals. In: Hobson DW, ed. Dermal and Ocular Toxicology Fundamentals and Methods. Boca Raton, FL: CRC Press, 1991. pp. 130-1
  • Nicolazzo JA, Morgan TM, Reed BL, et al. Synergistic enhancement of testosterone transdermal delivery. J Control Release 2005;103:577-85
  • Buxton PK, Morris-Jones R. ABC of Dermatology. 5th edn. Oxford: Wiley-Blackwell/BMJ Books, 2009
  • Frosch PJ, Kligman AM. A method for appraising the stinging capacity of topically applied substances. J Soc Cosmet Chem 1977;28:197-209
  • Kampf G, Loffler H. Prevention of irritant contact dermatitis among health care workers by using evidence-based hand hygiene practices: a review. Ind Health 2007;45:645-52
  • Strauss JS, Thiboutot DM. Diseases of the sebaceous glands. In: Freedberg IM, Eisen AXZ, Wolff K, et al., eds. Fitzpatrick’s Dermatology in General Medicine. NewYork: McGraw-Hill, 1999. pp. 769-84
  • Webster GF. Acne vulgaris. BMJ 2002;325:475-9
  • Wilhelm KP, Surber C, Maibach HI. Quantification of sodium lauryl sulfate irritant dermatitis in man: comparison of four techniques: skin color reflectance, transepidermal water loss, laser Doppler flow measurement and visual scores. Arch Dermatol Res 1989;281:293-5
  • Wang C, Swerdloff RS, Iranmanesh A, et al. Transdermal testosterone gel improves sexual function, mood, muscle strength, and body composition parameters in hypogonadal men. J Clin Endocrinol Metab 2000;85:2839-53
  • Steidle C, Schwartz S, Jacoby K, et al. AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function. J Clin Endocrinol Metab 2003;88:2673-81
  • Daniels F,Jr van der Leun JC. Problems in quantifying skin reactions. Arch Dermatol 1968;97:553-65

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.