11
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Gemfibrozil in hyperlipidaemic patients with peripheral arterial disease: some undiscovered actions

, &
Pages 207-214 | Received 05 Dec 1989, Published online: 12 Aug 2008

References

  • Agrati A. M., Ambrosi G., Ferraro G., Palmieri G. Gemfibrozil efficacy vs pantethine in dyslipoproteinemic patients: a controlled study. Curr. Tber. Res. 1989; 45: 650–6631. Agrati A. M., Ambrosi G., Ferraro G., Palmieri G. Gemfibrozil efficacy vs pantethine in dyslipoproteinemic patients: a controlled study. Curr. Tber. Res. 1989; 45: 650–663
  • Avellone G., Di Garbo V., Panno A. V., Cordova R., Lepore R., Strano A. Changes induced by gemfibrozil on lipidic, coagulative and fibrinolytic pattern in patients with type IV hyperlipoproteinemia. Int. Angiol. 1988; 7: 270–2772. Avellone G., Di Garbo V., Panno A. V., Cordova R., Lepore R., Strano A. Changes induced by gemfibrozil on lipidic, coagulative and fibrinolytic pattern in patients with type IV hyperlipoproteinemia. Int. Angiol. 1988; 7: 270–277
  • Berg K. Effect of gemfibrozil on lipid apoprotein parameters. Res Clin. Forums 1982; 4: 85–923. Berg K. Effect of gemfibrozil on lipid apoprotein parameters. Res Clin. Forums 1982; 4: 85–92
  • Bruckert E., de Carvalho Sousa J., Giral P., Soria C., Chapman M. J., Caen J., de Gennes J. Interrelationship of plasma triglyceride and coagulant factor VII levels in normotriglyceridemic hypercholesterolemia. Atherosclerosis 1989; 75: 129–1344. Bruckert E., de Carvalho Sousa J., Giral P., Soria C., Chapman M. J., Caen J., de Gennes J. Interrelationship of plasma triglyceride and coagulant factor VII levels in normotriglyceridemic hypercholesterolemia. Atherosclerosis 1989; 75: 129–134
  • Dacie J., Lewis S. M. Practical Haematology6th edit. Churchill Livingstone, Edinburgh 1984; 230–2335. Dacie J., Lewis S. M. Practical Haematology6th edit. Churchill Livingstone, Edinburgh 1984; 230–233
  • Dormandy J. A., Hoare E., Khattab A. H., Arrowsmith D. E., Dormandy T. L. Prognostic significance of rheological and biochemical findings in patients with intermittent claudication. Br. Med. J. 1073; 4: 581–5836. Dormandy J. A., Hoare E., Khattab A. H., Arrowsmith D. E., Dormandy T. L. Prognostic significance of rheological and biochemical findings in patients with intermittent claudication. Br. Med. J. 1073; 4: 581–583
  • Dormandy J. A., Gutteridge J. M. C., Hoare E., Dormandy T. L. Effect of clofibrate on blood viscosity in intermittent claudication. Bt. Med. J. 1974; 4: 259–2627. Dormandy J. A., Gutteridge J. M. C., Hoare E., Dormandy T. L. Effect of clofibrate on blood viscosity in intermittent claudication. Bt. Med. J. 1974; 4: 259–262
  • Duffield R. G., Lewis B., Miller N. E., Jamieson C. W., Brunt J. N. H., Colchester A. C. F. Treatment of hyperlipidaemia retards progression of symptomatic femoral atherosclerosis. Lancet 1983; 2: 639–6428. Duffield R. G., Lewis B., Miller N. E., Jamieson C. W., Brunt J. N. H., Colchester A. C. F. Treatment of hyperlipidaemia retards progression of symptomatic femoral atherosclerosis. Lancet 1983; 2: 639–642
  • El-Saadani M., Esterbauer H., El-Sayed M., Goher M., Nassar A. Y., Jurgens G. A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent. J. Lipid Res. 1989; 30: 627–6299. El-Saadani M., Esterbauer H., El-Sayed M., Goher M., Nassar A. Y., Jurgens G. A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent. J. Lipid Res. 1989; 30: 627–629
  • European Atherosclerosis Society Study Group. The recognition and management of hyperlipidaemia in adults: a policy statement of the European Atherosclerosis Society. Eur. Heart J. 1988; 9: 571–60010. European Atherosclerosis Society Study Group. The recognition and management of hyperlipidaemia in adults: a policy statement of the European Atherosclerosis Society. Eur. Heart J. 1988; 9: 571–600
  • Frick M. H., Elo O., Haapa K., et al. Helsinki Heart Study: primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia. N. Engl. J. Med. 1987; 317: 1237–124511. Frick M. H., Elo O., Haapa K., et al. Helsinki Heart Study: primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia. N. Engl. J. Med. 1987; 317: 1237–1245
  • Greenhalgh R. M., Lewis B., Rosengarten D. S., Calnan J. S., Mervart I., Martin P. Serum lipids and lipoproteins in peripheral vascular disease. Lancet 1971; 2: 947–95012. Greenhalgh R. M., Lewis B., Rosengarten D. S., Calnan J. S., Mervart I., Martin P. Serum lipids and lipoproteins in peripheral vascular disease. Lancet 1971; 2: 947–950
  • Hodges R., Marcus E. Safety of gemfibrozil (Lopid) in clinical use. Res. Clin. Forums 1982; 4: 35–4213. Hodges R., Marcus E. Safety of gemfibrozil (Lopid) in clinical use. Res. Clin. Forums 1982; 4: 35–42
  • Jurgens G., Ashy A., Zenker G. Raised serum lipoprotein during treatment with lovastatin. Lancet 1989; 1: 911–91214. Jurgens G., Ashy A., Zenker G. Raised serum lipoprotein during treatment with lovastatin. Lancet 1989; 1: 911–912
  • Kaukola S., Malkonen M., Koshinen P. Long-term treatment with gemfibrozil in male survivors of myocardial infarction. Further Progress with Gemfibrozil. International Congress and Symposium Series No. 87, R. Soc. Med. Services, London 1986; 35–4015. Kaukola S., Malkonen M., Koshinen P. Long-term treatment with gemfibrozil in male survivors of myocardial infarction. Further Progress with Gemfibrozil. International Congress and Symposium Series No. 87, R. Soc. Med. Services, London 1986; 35–40
  • Leschke M., Hoffken H., Martin J., Motz W., Strauer B. E. Improved blood fluidity and myocardial microcirculation due to fenofibrate therapy. Clin. Hemorheol. 1989; 9: 494(A)16. Leschke M., Hoffken H., Martin J., Motz W., Strauer B. E. Improved blood fluidity and myocardial microcirculation due to fenofibrate therapy. Clin. Hemorheol. 1989; 9: 494(A)
  • Loeper J., Emerit J., Goy J., Bedu O., Loeper J. Lipid peroxidation during human atherosclerosis. I.R.C.S. Med. Sci. 1983; 11: 1034–103517. Loeper J., Emerit J., Goy J., Bedu O., Loeper J. Lipid peroxidation during human atherosclerosis. I.R.C.S. Med. Sci. 1983; 11: 1034–1035
  • Maxwell R. E., Nawrocki J. W., Uhlendorf P. D. Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats. Atherosrclerosis 1983; 48: 195–20318. Maxwell R. E., Nawrocki J. W., Uhlendorf P. D. Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats. Atherosrclerosis 1983; 48: 195–203
  • Meade T. W., North W. R. S., Chakrabarti R., et al. Haemostatic function and cardiovascular death: early results of a prospective study. Lancet 1980; 1: 1050–105419. Meade T. W., North W. R. S., Chakrabarti R., et al. Haemostatic function and cardiovascular death: early results of a prospective study. Lancet 1980; 1: 1050–1054
  • Mitropoulos K. A., Miller G. J., Reeves B. E. A., Wilkes H. C., Cruickshank J. K. Factor VII coagulant activity is strongly associated with the plasma concentration of large lipoprotein particles in middle-aged men. Atherosclerosis 1989; 76: 203–20820. Mitropoulos K. A., Miller G. J., Reeves B. E. A., Wilkes H. C., Cruickshank J. K. Factor VII coagulant activity is strongly associated with the plasma concentration of large lipoprotein particles in middle-aged men. Atherosclerosis 1989; 76: 203–208
  • Ninrt G., Bulgarelli A., Cassader M., Pagano G. Effect of short term treatment with bezafibrate on plasma fibrinogen, fibrinopeptide A, platelet activation and blood filterability in atherosclerotic hyperfibrinogenemic patients. Atherosclerosis 1988; 71: 113–11921. Ninrt G., Bulgarelli A., Cassader M., Pagano G. Effect of short term treatment with bezafibrate on plasma fibrinogen, fibrinopeptide A, platelet activation and blood filterability in atherosclerotic hyperfibrinogenemic patients. Atherosclerosis 1988; 71: 113–119
  • Nishigaki I., Hagihara M., Tsunekawa H., Maseki M., Yagi K. Lipid peroxide levels of serum lipoprotein fractions of diabetic patients. Biochem. Med. 1981; 25: 373–37822. Nishigaki I., Hagihara M., Tsunekawa H., Maseki M., Yagi K. Lipid peroxide levels of serum lipoprotein fractions of diabetic patients. Biochem. Med. 1981; 25: 373–378
  • Olsson A. G., Erikson U., Helmius G., Hemmingsson A., Ruhn G. The effect of pronounced serum lipid lowering for one year on the development of femoral atherosclerosis in asymptomatic hyperlipoproteinaemia. Atherosclerosis 1986; 7: 89–9423. Olsson A. G., Erikson U., Helmius G., Hemmingsson A., Ruhn G. The effect of pronounced serum lipid lowering for one year on the development of femoral atherosclerosis in asymptomatic hyperlipoproteinaemia. Atherosclerosis 1986; 7: 89–94
  • Samuel P. Efficacy of gemfibrozil as a lipid regulator in a patient population in the United States. Vasc. Med. 1984; 2: 8–1524. Samuel P. Efficacy of gemfibrozil as a lipid regulator in a patient population in the United States. Vasc. Med. 1984; 2: 8–15
  • Sorisky A., Ooi T. C., Simo I. E., Meuffels M., Hindmarsh J. T., Nair R. Change in composition of high density lipoprotein during gemfibrozil therapy. Atherosclerosis. 1987; 67: 181–18925. Sorisky A., Ooi T. C., Simo I. E., Meuffels M., Hindmarsh J. T., Nair R. Change in composition of high density lipoprotein during gemfibrozil therapy. Atherosclerosis. 1987; 67: 181–189
  • Stone M. C., Thorpe J. M. Plasma fibrinogen— a major coronary risk factor. J. R. Coll. Gen. Pract. 1985; 35: 565–56926. Stone M. C., Thorpe J. M. Plasma fibrinogen— a major coronary risk factor. J. R. Coll. Gen. Pract. 1985; 35: 565–569
  • Stringer M. D., Gorog P. G., Freeman A., Kakkar V. V. Lipid peroxides and atherosclerosis. Bi. Med. J. 1989; 298: 281–28427. Stringer M. D., Gorog P. G., Freeman A., Kakkar V. V. Lipid peroxides and atherosclerosis. Bi. Med. J. 1989; 298: 281–284
  • Szamosi T., Gari I., Venekei I., Javor A., Ceskel R., Knoll J. Serum lipids, lipid peroxides and the care of children with high risk atherosclerotic family history. Atherosclerosis. 1987; 68: 111–11528. Szamosi T., Gari I., Venekei I., Javor A., Ceskel R., Knoll J. Serum lipids, lipid peroxides and the care of children with high risk atherosclerotic family history. Atherosclerosis. 1987; 68: 111–115
  • Vessby B., Lithell H., Boberg J., Hellsing K., Werner I. Gemfibrozil as a lipid lowering compound in hyperlipoproteinaemia. A placebo-controlled cross-over trial. Proc. R. Soc. Med. 1976; 69(Suppl. 2)32–3729. Vessby B., Lithell H., Boberg J., Hellsing K., Werner I. Gemfibrozil as a lipid lowering compound in hyperlipoproteinaemia. A placebo-controlled cross-over trial. Proc. R. Soc. Med. 1976; 69(Suppl. 2)32–37
  • Vessby B., Boberg M., Lithell H. Influence of gemfibrozil on lipoprotein composition: triglyceride removal capacity and fatty acid composition of the plasma lipid esters. Further Progress with Gemfibrozil. International Congress and Symposium Series No. 87, R. Soc. Med. Services, London 1986; 1–1030. Vessby B., Boberg M., Lithell H. Influence of gemfibrozil on lipoprotein composition: triglyceride removal capacity and fatty acid composition of the plasma lipid esters. Further Progress with Gemfibrozil. International Congress and Symposium Series No. 87, R. Soc. Med. Services, London 1986; 1–10
  • Wade C. R., van Rij A. M. Plasma malondialdehyde, lipid peroxides, and the thiobarbituric acid reaction. Clin. Chem. 1989; 35: 33631. Wade C. R., van Rij A. M. Plasma malondialdehyde, lipid peroxides, and the thiobarbituric acid reaction. Clin. Chem. 1989; 35: 336
  • Wilhelmsen L., Svardsudd K., Korsan-Bengtsen K., Larsson B., Welin L., Tibblin G. Fibrinogen as a risk factor for stroke and myocardial infarction. N. Engl. J. Med. 1984; 311: 501–50532. Wilhelmsen L., Svardsudd K., Korsan-Bengtsen K., Larsson B., Welin L., Tibblin G. Fibrinogen as a risk factor for stroke and myocardial infarction. N. Engl. J. Med. 1984; 311: 501–505

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.