Efficacy and Tolerability of Azelastine Nasal Spray in the Treatment of Allergic Rhinitis: Large Scale Experience in Community Practice

References

• Achterrath-Tuckerniann U., Simmet T., Luck W., Szelenyi I., Peskar B. A. Inhibition of cysteinyl-leukotriene production by azelastine and its biological significance. Agents Action. 1988; 24: 217, 2231. Achterrath-Tuckerniann U., Simmet T., Luck W., Szelenyi I., Peskar B. A. Inhibition of cysteinyl-leukotriene production by azelastine and its biological significance. Agents Action. 1988; 24: 217, 223
   PubMedGoogle Scholar
• Charpin D., Godard P., Garay R., Baehre M., Herman D., Michel F. B. A multicentre clinical study of the efficacy and tolerability of azelastine nasal spray in the treatment of seasonal allergic rhinitis: a comparison with oral cetirizine. Eur. Arch. Oforhinolntyzgol. 1995; 252: 455, 4582. Charpin D., Godard P., Garay R., Baehre M., Herman D., Michel F. B. A multicentre clinical study of the efficacy and tolerability of azelastine nasal spray in the treatment of seasonal allergic rhinitis: a comparison with oral cetirizine. Eur. Arch. Oforhinolntyzgol. 1995; 252: 455, 458
   PubMed Web of Science ®Google Scholar
• Ciprandi G., Pronzanto C., Passalacqua G., Ricca V., Verese P., Bertolini C., Bagnasco M., Canonica G. W. Topical azelastine reduces ICAM-I expression on nasal epithelial cells: an anti-allergic activity. J. Allerg. Clin. Immunol. 1996; 12: 1088, 10963. Ciprandi G., Pronzanto C., Passalacqua G., Ricca V., Verese P., Bertolini C., Bagnasco M., Canonica G. W. Topical azelastine reduces ICAM-I expression on nasal epithelial cells: an anti-allergic activity. J. Allerg. Clin. Immunol. 1996; 12: 1088, 1096
   Google Scholar
• Conde Hernandez J., Palma Aguilar J. L., Delgado Romero J. Comparison of azelastine nasal spray and oral ebastine in treating seasonal allergic rhinitis. Curr. Med. Res. Opin. 1995; 13: 299, 3044. Conde Hernandez J., Palma Aguilar J. L., Delgado Romero J. Comparison of azelastine nasal spray and oral ebastine in treating seasonal allergic rhinitis. Curr. Med. Res. Opin. 1995; 13: 299, 304
   PubMed Web of Science ®Google Scholar
• Davies R. J., Lund V. J., Harten-Ash V. J. The effect of intranasal azelastine and beclomethasonc on the symptoms and signs of nasal allergy in patients with perennial allergic rhinitis. Rhinol. 1993; 31: 15P–1645. Davies R. J., Lund V. J., Harten-Ash V. J. The effect of intranasal azelastine and beclomethasonc on the symptoms and signs of nasal allergy in patients with perennial allergic rhinitis. Rhinol. 1993; 31: 15P–164
   Google Scholar
• Dorow P., Aurich R., Petzold U. Efficacy and tolerability of azelastine nasal spray in patients with nasal allergy compared to placebo and budesonide. Arzneim.-Forsch./Drug Res. 1993; 43: 909, 9126. Dorow P., Aurich R., Petzold U. Efficacy and tolerability of azelastine nasal spray in patients with nasal allergy compared to placebo and budesonide. Arzneim.-Forsch./Drug Res. 1993; 43: 909, 912
   PubMed Web of Science ®Google Scholar
• Gastpar H., Aurich R., Petzold U., Dorow P., Enzmann H., Gerling R., Köchy K. P., Philipp A., Rcnz W., Wendenburg G. Intranasal treatment of perennial allergic rhinitis: azelastine nasal spray versus budesonide aerosol. Arzneim.-Forsch./Drug Rex 1993; 43: 475, 4797. Gastpar H., Aurich R., Petzold U., Dorow P., Enzmann H., Gerling R., Köchy K. P., Philipp A., Rcnz W., Wendenburg G. Intranasal treatment of perennial allergic rhinitis: azelastine nasal spray versus budesonide aerosol. Arzneim.-Forsch./Drug Rex 1993; 43: 475, 479
   PubMed Web of Science ®Google Scholar
• Gastpar H. Comparison of efficacy and tolerability of azelastine nasal spray and budenoside nasal aerosol in patients with perennial allergic rhinitis. Study No. 2730. ASTA Pharma AC. 19908. Gastpar H. Comparison of efficacy and tolerability of azelastine nasal spray and budenoside nasal aerosol in patients with perennial allergic rhinitis. Study No. 2730. ASTA Pharma AC. 1990
   Google Scholar
• Gastpar H. Comparison of the efficacy and tolerability of an azelastine nasal spray with those of terfenadine on 6-week treatment of patients with allergic rhinitis (perennial). Study No. 2613. ASTA Pharma AG. 19899. Gastpar H. Comparison of the efficacy and tolerability of an azelastine nasal spray with those of terfenadine on 6-week treatment of patients with allergic rhinitis (perennial). Study No. 2613. ASTA Pharma AG. 1989
   Google Scholar
• Gering R. Comparison of efficacy and tolerability of azelastine nasal spray, azelastine tablets, and astemizole in the treatment of seasonal allergic rhinitis. Study No. 2758. ASTA Pharma AG. 199010. Gering R. Comparison of efficacy and tolerability of azelastine nasal spray, azelastine tablets, and astemizole in the treatment of seasonal allergic rhinitis. Study No. 2758. ASTA Pharma AG. 1990
   Google Scholar
• Herman D., Garay R., Le Gal M. A randomised double-blind placebo controlled study of azelastine nasal spray in children with perennial rhinitis. Int. J. Ped. Otorhinolaryngol. 1997; 39: 1–811. Herman D., Garay R., Le Gal M. A randomised double-blind placebo controlled study of azelastine nasal spray in children with perennial rhinitis. Int. J. Ped. Otorhinolaryngol. 1997; 39: 1–8
   PubMed Web of Science ®Google Scholar
• Kurzeja A. H. Comparison of the efficacy and tolerability of an azelastine HCI nasal spray with those of terfenadine on 6-week treatment of patients with allergic rhinitis. Study No. 2610. ASTA Pharma AG. 198912. Kurzeja A. H. Comparison of the efficacy and tolerability of an azelastine HCI nasal spray with those of terfenadine on 6-week treatment of patients with allergic rhinitis. Study No. 2610. ASTA Pharma AG. 1989
   Google Scholar
• Laessig W., Wober W., Hoflich C., Bähre M., Roloff A. Topical therapy for allergic rhinitis in childhood: Allergodil nasal spray — non-sedating in children. Curr. Med. Res. Opin. 1996; 13: 391, 39513. Laessig W., Wober W., Hoflich C., Bähre M., Roloff A. Topical therapy for allergic rhinitis in childhood: Allergodil nasal spray — non-sedating in children. Curr. Med. Res. Opin. 1996; 13: 391, 395
   PubMed Web of Science ®Google Scholar
• Masuo M., Shiniada T., Kitazawa T. Mechanism of inhibitory effects of azelastine on smooth muscle contraction. J. Pharmacol. Exp. Ther. 1992; 260: 1300, 130814. Masuo M., Shiniada T., Kitazawa T. Mechanism of inhibitory effects of azelastine on smooth muscle contraction. J. Pharmacol. Exp. Ther. 1992; 260: 1300, 1308
   PubMed Web of Science ®Google Scholar
• McTavish D., Sorkin E. M. Azelastine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Drugs 1989; 38: 778, 80015. McTavish D., Sorkin E. M. Azelastine: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Drugs 1989; 38: 778, 800
   PubMed Web of Science ®Google Scholar
• Morganroth J., Perhach J. L., Lyness W., Rosenberg A. Lack of effect of azelastine alone and co-administered with ketoconazole on electrocardiographic parameters. J. Allerg. Clin. Immunol. 1995; 95: 28216. Morganroth J., Perhach J. L., Lyness W., Rosenberg A. Lack of effect of azelastine alone and co-administered with ketoconazole on electrocardiographic parameters. J. Allerg. Clin. Immunol. 1995; 95: 282
   Google Scholar
• Mosges R., Spaeth J., Conrad F., Giani G. Azelastine - Nasenspray in der allergologischen Praxis. HNO aktuell 1995; 3: 173, 17617. Mosges R., Spaeth J., Conrad F., Giani G. Azelastine - Nasenspray in der allergologischen Praxis. HNO aktuell 1995; 3: 173, 176
   Google Scholar
• Nolte D. Comparison of the efficacy and tolerability of azelastine HCI nasal spray with those of terfenadine on 6-weeks treatment of patients with allergic rhinitis (seasonal). Study No. 2606. ASTA Pharma AG. 198918. Nolte D. Comparison of the efficacy and tolerability of azelastine HCI nasal spray with those of terfenadine on 6-weeks treatment of patients with allergic rhinitis (seasonal). Study No. 2606. ASTA Pharma AG. 1989
   Google Scholar