Imaging Pain in the Brain: The Role of the Cerebral Cortex in Pain Perception and Modulation

REFERENCES

• Craig A D, Bushnell M C. The thermal grill illusion: Unmasking the burn of cold pain. Science 1994; 265: 252–255
   PubMed Web of Science ®Google Scholar
• Craig A D, Reiman E M, Evans A C, Bushnell M C. Functional imaging of an illusion of pain. Nature 1996; 384: 258–260
   PubMed Web of Science ®Google Scholar
• Beecher H K. Pain in men wounded in battle. Ann Surg 1946; 123: 96–105
   PubMed Web of Science ®Google Scholar
• Talbot J D, Marrett S, Evans A C, Meyer E, Bushnell M C, Duncan G H. Multiple representations of pain in human cerebral cortex. Science 1991; 251: 1355–1358
   PubMed Web of Science ®Google Scholar
• Jones A KP, Brown W D, Friston K J, Qi L Y, Frackowiak R SJ. Cortical and subcortical localization of response to pain in man using positron emission tomography. Proc R Soc Lond [Biol] 1991; 244: 39–44
   PubMed Web of Science ®Google Scholar
• Coghill R C, Talbot J D, Evans A C, Meyer E, Gjedde A, Bushnell M C, Duncan G H. Distributed processing of pain and vibration by the human brain. J Neurosci 1994; 14: 4095–4108
   PubMed Web of Science ®Google Scholar
• Derbyshire S W, Jones A K, Devani P, Friston K J, Feinmann C, Harris M, Pearce S, Watson J D, Frackowiak R S. Cerebral responses to pain in patients with atypical facial pain measured by positron emission tomography. J Neurol Neurosurg Psychiatry 1994; 57: 1166–1172
   PubMed Web of Science ®Google Scholar
• Casey K L, Minoshima S, Morrow T J, Koeppe R A. Comparison of human cerebral activation patterns during cutaneous warmth, heat pain, and deep cold pain. J Neurophysiol 1996; 76: 571–581
   PubMed Web of Science ®Google Scholar
• Bushnell M C, Duncan G H, Ha B, Chen J-I, Olausson H. Non-invasive brain imaging during experimental and clinical pain. Proceedings of the 9th World Congress in Pain Research and Management, M Devor, M C Rowbotham, Z Wiesenfeld-Hallin. IASP Press. 2000; 16: 485–495
   Google Scholar
• Craig A D, Chen K, Bandy D, Reiman E M. Thermosensory activation of insular cortex. Nat Neurosci 2000; 3: 184–190
   PubMed Web of Science ®Google Scholar
• Iadarola M J, Berman K F, Zeffiro T A, Byas-Smith M G, Gracely R H, Max M B, Bennett G J. Neural activation during acute capsaicin-evoked pain and allodynia assessed with PET. Brain 1998; 121(Pt 5)931–947
   PubMedGoogle Scholar
• Baron R, Baron Y, Disbrow E, Roberts T P. Brain processing of capsaicin-induced secondary hyperalgesia: a functional MRI study. Neurology 1999; 53: 548–557
   PubMed Web of Science ®Google Scholar
• Svensson P, Minoshima S, Beydoun A, Morrow T J, Casey K L. Cerebral processing of acute skin and muscle pain in humans. J Neurophysiol 1997; 78: 450–460
   PubMed Web of Science ®Google Scholar
• Silverman D H, Munakata J A, Ennes H, Mandelkern M A, Hoh C K, Mayer E A. Regional cerebral activity in normal and pathological perception of visceral pain. Gastroenterology 1997; 112: 64–72
   PubMed Web of Science ®Google Scholar
• Aziz Q, Andersson J L, Valind S, Sundin A, Hamdy S, Jones A K, Foster E R, Langstrom B, Thompson D G. Identification of human brain loci processing esophageal sensation using positron emission tomography. Gastroenterology 1997; 113: 50–59
   PubMed Web of Science ®Google Scholar
• Binkofski F, Schnitzler A, Enck P, Frieling T, Posse S, Seitz R J, Freund H J. Somatic and limbic cortex activation in esophageal distention: a functional magnetic resonance imaging study. Ann Neurol 1998; 44: 811–815
   PubMed Web of Science ®Google Scholar
• Derbyshire S W. Exploring the pain “neuromatrix.”. Curr Rev Pain 2000; 4: 467–477
   PubMedGoogle Scholar
• Sikes R W, Vogt B A. Nociceptive neurons in area 24 of rabbit cingulate cortex. J Neurophysiol 1992; 68: 1720–1732
   PubMed Web of Science ®Google Scholar
• Dong W K, Salonen L D, Kawakami Y, Shiwaku T, Kaukoranta E M, Martin R F. Nociceptive responses of trigeminal neurons in SII-7b cortex of awake monkeys. Brain Res 1989; 484: 314–324
   PubMedGoogle Scholar
• Kenshalo D R, Jr., Isensee O. Responses of primate SI cortical neurons to noxious stimuli. J Neurophysiol 1983; 50: 1479–1496
   PubMed Web of Science ®Google Scholar
• Burkey A R, Carstens E, Wenniger J J, Tang J W, Jasmin L. An opioidergic cortical antinociception triggering site in the agranular insular cortex of the rat that contributes to morphine antinociception. Journal of Neuroscience 1996; 16: 6612–6623
   PubMed Web of Science ®Google Scholar
• Hutchison W D, Davis K D, Lozano A M, Tasker R R, Dostrovsky J O. Pain-related neurons in the human cingulate cortex. Nat Neurosci 1999; 2: 403–405
   PubMed Web of Science ®Google Scholar
• Melzack R, Casey K L. Sensory, motivational and central control determinants of pain: a new conceptual model. The Skin Senses, D R Kenshalo, Springfield, IL 1968; 423–443
   Google Scholar
• Iadarola M J, Max M B, Berman K F, Byas-Smith M G, Coghill R C, Gracely R H, Bennett G J. Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain. Pain 1995; 63: 55–64
   PubMed Web of Science ®Google Scholar
• Hsieh J C, Belfrage M, Stone-Elander S, Hansson P, Ingvar M. Central representation of chronic ongoing neuropathic pain studied positron emission tomography. Pain 1995; 63: 225–236
   PubMed Web of Science ®Google Scholar
• Cesaro P, Mann M W, Moretti J L, Defer G, Roualdès B, Nguyen J P, Degos J D. Central pain and thalamic hyperactivity: a single photon emission computerized tomographic study. Pain 1991; 47: 329–336
   PubMed Web of Science ®Google Scholar
• Canavero S, Pagni C A, Castellano G, Bonicalzi V, Bello' M, Duca S, Podio V. The role of cortex in central pain syndromes: preliminary results of a long-term techne-tium-99 hexamethylpropyleneamineoxime single photon emission computed tomography study. Neurosurgery 1993; 32: 185–191
   PubMed Web of Science ®Google Scholar
• Peyron R, Garcia-Larrea L, Gregoire M C, Convers P, Lavenne F, Veyre L, Froment J C, Mauguiere F, Michel D, Laurent B. Allodynia after lateral-medullary (Wallenberg) infarct. A PET study. Brain 1998; 121(Pt 2)345–356
   PubMedGoogle Scholar
• Peyron R, Garcia-Larrea L, Gregoire M C, Convers P, Richard A, Lavenne F, Barral F G, Mauguiere F, Michel D, Laurent B. Parietal and cingulate processes in central pain. A combined positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) study of an unusual case. Pain 2000; 84: 77–87
   PubMed Web of Science ®Google Scholar
• Olausson H, Marchand S, Bittar R G, Bernier J, Ptito A, Bushnell M C. Central pain in a hemispherectomized patient. Eur J Pain 2001; 5: 209–218
   PubMedGoogle Scholar
• Wolfe F, Ross K, Anderson J, Russell I J, Hebert L. The prevalence and characteristics of fibromyalgia in the general population. Arthritis Rheum 1995; 38: 19–28
   PubMed Web of Science ®Google Scholar
• Kwiatek R, Barnden L, Tedman R, Jarrett R, Chew J, Rowe C, Pile K. Regional cerebral blood flow in fibromyalgia: single-photon-emission computed tomography evidence of reduction in the pontine tegmentum and thalami. Arthritis Rheum 2000; 43: 2823–2833
   PubMed Web of Science ®Google Scholar
• Lekander M, Fredrikson M, Wik G. Neuroimmune relations in patients with fibromyalgia: a positron emission tomography study. Neurosci Lett 2000; 282: 193–196
   PubMedGoogle Scholar
• Katayama Y, Tsubokawa T, Yamamoto T. Chronic motor cortex stimulation for central deafferentation pain: experience with bulbar pain secondary to Wallenberg syndrome. Stereotact Funct Neurosurg 1994; 62: 295–299
   PubMedGoogle Scholar
• Peyron R, Garcia-Larrea L, Deiber M P, Cinotti L, Convers P, Sindou M, Mauguière F, Laurent B. Electrical stimulation of precentral cortical area in the treatment of central pain: electrophysiological and PET study. Pain 1995; 62: 275–286
   PubMed Web of Science ®Google Scholar
• Katayama Y, Fukaya C, Yamamoto T. Poststroke pain control by chronic motor cortex stimulation: neurological characteristics predicting a favorable response. J Neurosurg 1998; 89: 585–591
   PubMed Web of Science ®Google Scholar
• Casey K L, Svensson P, Morrow T J, Raz J, Jone C, Minoshima S. Selective opiate modulation of nociceptive processing in the human brain. J Neurophysiol 2000; 84: 525–533
   PubMed Web of Science ®Google Scholar
• Zubieta J K, Smith Y R, Bueller J A, Xu Y, Kilbourn M R, Jewett D M, Meyer C R, Koeppe R A, Stohler C S. Regional mu opioid receptor regulation of sensory and affective dimensions of pain. Science 2001; 293: 311–315
   PubMed Web of Science ®Google Scholar
• Miron D, Duncan G H, Bushnell M C. Effects of attention on the intensity and unpleasantness of thermal pain. Pain 1989; 39: 345–352
   PubMed Web of Science ®Google Scholar
• Leventhal H, Brown D, Shacham S, Engquist G. Effects of preparatory information about sensations, threat of pain, and attention on cold pressor distress. J Pers Soc Psychol 1979; 37: 688–714
   PubMed Web of Science ®Google Scholar
• Levine J D, Gordon N C, Smith R, Fields H L. Post-operative pain: effect of extent of injury and attention. Brain Res 1982; 234: 500–504
   PubMedGoogle Scholar
• McCaul K D, Haugtvedt C. Attention, distraction, and cold-pressor pain. J Pers Soc Psychol 1982; 43: 154–162
   PubMedGoogle Scholar
• Enqvist B, Fischer K. Preoperative hypnotic techniques reduce consumption of analgesics after surgical removal of third mandibular molars: a brief communication. Int J Exp Hypn 1997; 45: 102–108
   PubMed Web of Science ®Google Scholar
• Rainville P, Duncan G H, Price D D, Carrier B, Bushnell M C. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science 1997; 277: 968–971
   PubMed Web of Science ®Google Scholar
• Hofbauer R K, Rainville P, Duncan G H, Bushnell M C. Cortical representation of the sensory dimension of pain. J Neurophysiol 2001; 86: 402–411
   PubMed Web of Science ®Google Scholar
• Bushnell M C, Duncan G H, Hofbauer R K, Ha B, Chen J, Carrier B. Pain perception: is there a role for primary somatosensory cortex?. Proc Natl Acad Sci USA 1999; 96: 7705–7709
   PubMed Web of Science ®Google Scholar
• Longe S E, Wise R, Bantick S, Lloyd D, Johansen-Berg H, McGlone F, Tracey I. Counter-stimulatory effects on pain perception and processing are significantly altered by attention: an fMRI study. NeuroReport 2001; 12: 2021–2025
   PubMed Web of Science ®Google Scholar
• Petrovic P, Petersson K M, Ghatan P H, Stone-Elander S, Ingvar M. Pain-related cerebral activation is altered by a distracting cognitive task. Pain 2000; 85: 19–30
   PubMed Web of Science ®Google Scholar
• Peyron R, Garcia-Larrea L, Gregoire M C, Costes N, Convers P, Lavenne F, Mauquire F, Michel D, Laurent B. Haemodynamic brain responses to acute pain in humans: sensory and attentional networks. Brain 1999; 122: 1765–1780
   PubMed Web of Science ®Google Scholar
• Yang J C, Clark W C, Tsui S L, Ng K F, Clark S B. Preoperative Multidimensional Affect and Pain Survey (MAPS) scores predict postcolectomy analgesia requirement. Clin J Pain 2000; 16: 314–320
   PubMed Web of Science ®Google Scholar
• Schanberg L E, Sandstrom M J, Starr K, Gil K M, Lefebvre J C, Keefe F J, Affleck G, Tennen H. The relationship of daily mood and stressful events to symptoms in juvenile rheumatic disease. Arthritis Care Res 2000; 13: 33–41
   PubMed Web of Science ®Google Scholar
• Kvaal S A, Patodia S. Relations among positive affect, negative affect, and somatic symptoms in a medically ill patient sample. Psychol Rep 2000; 87: 227–233
   PubMedGoogle Scholar
• Haythornthwaite J A, Benrud-Larson L M. Psychological aspects of neuropathic pain. Clin J Pain 2000; 16: S101, S105
   PubMed Web of Science ®Google Scholar
• Fernandez E, Milburn T W. Sensory and affective predictors of overall pain and emotions associated with affective pain. Clin J Pain 1994; 10: 3–9
   PubMedGoogle Scholar
• Weisenberg M, Raz T, Hener T. The influence of film-induced mood on pain perception. Pain 1998; 76: 365–375
   PubMed Web of Science ®Google Scholar
• Good M. Effects of relaxation and music on postoperative pain: a review. J Adv Nurs 1996; 24: 905–914
   PubMed Web of Science ®Google Scholar
• Zillmann D, De Wied M, King-Jablonski C, Jenzowsky S. Drama-induced affect and pain sensitivity. Psychosom Med 1996; 58: 333–341
   PubMedGoogle Scholar
• Magill-Levreault L. Music therapy in pain and symptom management. J Palliat Care 1993; 9: 42–48
   PubMedGoogle Scholar
• Royet J P, Zald D, Versace R, Costes N, Lavenne F, Koenig O, Gervais R. Emotional responses to pleasant and unpleasant olfactory, visual, and auditory stimuli: a positron emission tomography study. J Neurosci 2000; 20: 7752–7759
   PubMed Web of Science ®Google Scholar
• Coghill R C, Sang C N, Maisog J M, Iadarola M J. Pain intensity processing within the human brain: a bilateral, distributed mechanism. J Neurophysiol 1999; 82: 1934–1943
   PubMed Web of Science ®Google Scholar