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Review

Existing and potential therapeutic approaches targeting peroxisome proliferator-activated receptors in the management of Type 2 diabetes

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Pages 1713-1733 | Published online: 22 Nov 2006

Bibliography

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  • HANSEN L, EKSTROM CT, TABANERA Y et al.: The Pro12Ala variant of the PPARG gene is a risk factor for PPAR-γ/α/agonist induced edema in Type 2 diabetic patients. J. Clin. Endocrinol. Metab. (2006) 91(9):3446-3450.
  • VESTERGAARD H, CLAUSEN J, BENEDIKTSSON R et al.: Insulin sensitivity and metabolic control in response to pioglitazone treatment differ between patients with Type 2 diabetes with and without the Pro12Ala variant in the PPAR-γ2 gene. ADA (2006) Washington Oral Presentation (321-OR).

Patents

Websites

  • http://www.kowa.co.jp/eng/g/rd/pipeline.htm Kowa Pharmaceuticals. Pipeline: 1 February (2006).
  • http://www.bms.com/news/press/data/fg_press_release_6384.html Press release: Bristol-Myers Squibb announces discontinuation of development of muraglitazar, an investigational oral treatment for Type 2 diabetes: 18 May (2006).
  • http://www.astrazeneca.com/pressrelease/5240.aspx Press release: AstraZeneca discontinues development of GALIDA TM (tesaglitazar): 4 May (2006).
  • http://www.takeda.com/press/04122001.htmPress release: Takeda announces to place its anti-diabetic agent TAK-559 on clinical hold. Takeda Pharmaceutical Company Ltd: 20 December (2004).
  • http://www.takeda.com/press/05033001.htmPress release: discontinuation of development of anti-diabetic agent TAK-559; Takeda Pharmaceutical Company Limited: 30 March (2005).
  • http://www.takeda.com/press/06090701.htmDiscontinuation of development of anti-diabetic agent TAK-654: 7 September (2006).
  • http://biz.yahoo.com/e/060515/lgnd10-q.html Form 10-Q for Ligand Pharmaceuticals Inc; quarterly report: 15 May (2006).
  • http://www.novonordisk.com/press Novo Nordisk suspends the clinical development of ragaglitazar: 22 Jul (2002).
  • http://www.trustbasedmarketing.com/sm/news.1539/newsdetail.aspx Faxwatch news headlines: Merck ends Phase III program for investigational diabetes treatment MK-767; shares fall: 21 Nov (2003)
  • http://www.ono.co.jp/eng/ii/f_ii.htm Status of development pipeline; as of 4 August (2006).
  • http://www.sanofi-aventis.com/rd/portfolio/p_rd_portfolio_metabo.asp Sanofi-aventis.
  • http://www.novartis.com/downloads_new/investors/planned_fillings_2006_2009.pdf
  • http://www.gsk.com/investors/product_pipeline/docs/pipeline.pdf Product development pipeline: February (2006).
  • http://www.drreddys.com/dresearch/discoverypipeline.htm Dr.Reddy's discovery pipeline.
  • http://www.plexxikon.com/overview.shtml Plexxicon/overwiev/discovery & development pipeline – portfolio of product opportunities.
  • http://www.chipscreen.com/en/about/news.htm Shenzhen Chipscreen Biosciences Ltd.
  • http://www.chipscreen.com/en/products_server/index.htm Shenzhen Chipscreen Biosciences Ltd. Product and pipeline.
  • http://www.metabolex.com/MetaglidasenMBX-2044.html Metabolex/Pipeline/Metaglidasen/MBX2044.
  • http://www.rheoscience.com/rheo_pdf/0509__Bala_Press_Release_Draft Dr. Reddy's announces India's first major drug co-development and commercialization deal.
  • http://www.perlegen.com/ Press Releases: Perlegen Sciences licenses late-stage compound from Mitsubishi Pharma: 12 April (2005).
  • http://www.lilly.com/investor/annual_report/lillyar2005.pdf

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