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Reviews

New aminoglycoside antibiotics

, PhD & , PhD
Pages 1321-1341 | Published online: 30 Jul 2010

Bibliography

  • Payne DJ, Gwynn MN, Holmes DJ, Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev Drug Discov 2007;6:29-40
  • Fischbach MA, Walsh CT. Antibiotics for emerging pathogens. Science 2009;325:1089-93
  • Boucher HW, Talbot GH, Bradley JS, Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 2009;48:1-12
  • Schatz A, Bugie E, Waksman SA. Streptomycin, a substance exhibiting antibiotic activity against Gram-positive and Gram-negative bacteria. Proc Soc Exp Biol Med 1944;55:66
  • Waksman SA. Streptomycin: background, isolation, properties, and utilization. Science 1953;118:259-66
  • Garrod LP, O'Grady F. Antibiotic chemotherapy. Livingstone, Edinburgh, 1968. p. 98
  • Hooper IR. Aminoglycoside antibiotics, Umezawa H, Hooper IR, editors,Springer Verlag, Berlin; 1982
  • Price KE, Godfrey JC, Kawaguchi H. Structure-activity relationships among the semisynthetic antibiotics. Perlman D, editor. Academic Press, New York; 1974
  • Magnet S, Blanchard JS. Molecular insights into aminoglycoside action and resistance. Chem Rev 2005;105:477-97
  • Fourmy D, Recht MI, Blanchard SC, Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic. Science 1996;274:1367-71
  • Carter AP, Clemons WM, Broderson DE, Functional insights from the structure if 30S ribosomal subunit and its interactions with antibiotics. Nature 2000;407:340-8
  • Wright GD. Aminoglycoside-modifying enzymes. Curr Opin Microbiol 1999;2:499-503
  • Jana S, Deb JK. Molecular understanding of aminoglycoside action and resistance. App Microbiol Biotechnol 2006;70:140-50
  • Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007;45:88-94
  • Mingeot-Leclercq M-P, Tulkens PM. Aminoglycosides: nephrotoxicity. Antimicrob Agents Chemother 1999;43:1003-12
  • Price KE, Godfrey JC, Kawaguchi H. Effect of structural modifications on the biological properties of aminoglycoside antibiotics containing 2-deoxystreptamine. Structure-activity relationships among the semisynthetic antibiotics, Perlman D, editor, Academic Press New York, San Francisco, London; 1977: p. 239-355
  • Reden J, Durckheimer W. Aminoglycoside antibiotics: chemisry, biochemistry, structure-activity relationship. Top Curr Chem 1979;83:105-70
  • Daniels PJL, Cooper AB, McCombie SW, Some recent advances in the chemistry of antibiotics of the gentamicin series. Jpn J Antibiot 1979;32:S195-204
  • Umezawa S, Tsuchiya T. Total synthesis and chemical modification of the aminoglycoside antibiotics. Aminoglycoside antibiotics. Umezawa H, Hooper IR, editors, Springer Verlag Berlin, Heidelberg, New York; 1982:37-110
  • Nagabhushan TL, Miller GH, Weinstein MJ. Structure-activity relationships in aminoglycoside-aminocyclitol antibiotics. In the aminoglycosides; microbiology, clinical use and toxicology, Whelton A, Neu HC, editors, Marcel Dekker, Inc., New York and Basel; 1982. p. 3-27
  • Wright GD, Berghuis AM, Mobashery S. Aminoglycoside antibiotics: structures, function, and resistance. Adv Exp Med Biol 1998;456:27-69
  • Kirst HA, Allen NE. Aminoglycoside antibiotics. Comprehensive medicinal chemistry II 2006;7:629-52
  • Li J, Chang C-WT. Recent developments in the synthesis of novel aminoglycoside antibiotics. Anti-Infect Agent Med Chem 2006;5:255-71
  • Silva JG, Carvalho I. New insights into aminoglycoside antibiotics and derivatives. Curr Med Chem 2007;14:1101-19
  • Hiraiwa Y, Usui T, Akiyama Y, Synthesis and antibacterial activity of 5-deoxy-5-episubstituted arbekacin derivatives. Bioorg Med Chem Lett 2007;17:3540-3
  • Meiji Seika. Novel aminoglycoside antibiotic effective against methicillin resistant staphylococcus aureus (MRSA). PCT/JP000767 (2005). WO070945; 2005
  • Hiraiwa Y, Minowa N, Usui T, Effect of varying the 4″-position of arbekacin derivatives on antibacterial activity against MRSA and Pseudomonas aeruginosa. Bioorg Med Chem Lett 2007;17:6369-72
  • Meiji Seika. Novel aminoglycoside antibiotics. PCT/JP061209 (2007), US0186841 (2009). WO142150; 2007
  • Meiji Seika. Novel aminoglycoside antibiotic, method for producing the same, and pharmaceutical use of the same. PCT/JP071795 (2008). WO069800; 2009
  • MIC values were provided only for the 2-hydroxy derivatives; kanamycin B data was measured on the same strains at Achaogen
  • Achaogen. Antibacterial aminoglycoside analogs. WO067692; 2009
  • Achaogen. Antibacterial 1,4,5-substituted aminoglycoside analogs. WO124821; 2008
  • Aggen JB, Armstrong ES, Goldblum AA, Synthesis, structure and in vitro activity of the neoglycoside ACHN-490. Poster F1-840, 49th ICAAC Conference; 12 – 15th September 2009; San Francisco, USA. Achaogen posters are accessible on their web site. Available from: http://www.achaogen.com/news/posters-scientific-publications/neoglycosides-2
  • Georgescu C, Martin DA, Bratu S, Activity of ACHN-490, a novel neoglycoside antibiotic, against contemporary Gram-negative clinical isolates from Brooklyn, NY hospitals. Poster F1-842, 49th ICAAC Conference; 12 – 15th September 2009; San Francisco, USA
  • Zurenko G, Stapert D, Knechtel M, The bacterial activity of the neoglycoside ACHN-490 against aminoglycoside-resistant bacteria. Poster F1-841, 49th ICAAC Conference; 12 – 15th September 2009; San Francisco, USA
  • Cass RT, McKinnell JV, Xie B, Pharmacokinetics of the novel neoglycoside ACHN-490 in mouse, rat and dog. Poster F1-846, 49th ICAAC Conference; 12 – 15th September 2009; San Francisco, USA
  • Reyes N, Aggen JB, Kostrub CF. In vivo efficacy of the neoglycoside ACHN-490 against Enterobacteriaceae and MRSA. Poster F1-845, 49th ICAAC Conference. 12 – 15th September 2009; San Francisco, USA
  • Bruss J, Brooks C, Havrilla N, Pharmacokinetics and safety of single and multiple doses of ACHN-490 injection administered intravenously in human subjects. Oral presentation F1-1223c, 49th ICAAC Conference. 12 – 15th September 2009; San Francisco, USA
  • ISIS Pharmaceuticals. Antibacterial 6'-modified 4,5-substituted aminoglycoside analogs. US0214845; 2008
  • Isis Pharmaceuticals. Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents. WO064954; 2007
  • Hanessian S, Szychowski J, Adhikari SS, Structure-based design, synthesis and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2″ ether analogues of paromomycin. J Med Chem 2007;50:2352-69
  • University of Manitoba, Canada. Triazole-based aminoglycoside-peptide conjugates and methods of use. WO037592; 2009
  • University of Manitoba, Canada. Hydrophobically enhanced aminoglycosides as antibacterial agents. WO004433; 2010
  • Bera S, Zhanel GG, Schweizer F. Design, synthesis, and antibacterial activities of neomyicn-lipid conjugates: polycationic lipids with potent Gram-positive activity. J Med Chem 2008;51:6160-4
  • Wuxi Suke Biotechnology. Application of amino glycoside antibiotic in preparing pharmaceutical composition for treating drug-resistant bacterial infection. Patent in Chinese, CN101152195; 2007
  • Huang Z. Aminoglycoside antibiotics derivative. Patent in Chinese, CN101074249; 2007
  • Huang Z. Aminoglycoside derivative. Patent in Chinese, CN101225093; 2008
  • Li Z. Novel kanamycin A derivative and preparation and use thereof. Patent in Chinese, CN101481397; 2009
  • Massachusetts Institute of Technology, Cambridge, USA. Bioactive molecules from co-cultivation of microbes. WO117036; 2009
  • Kurosawa K, Ghiviriga I, Sambandan TG, Rhodostreptomycins, antibiotics biosynthesized following horizontal gene transfer from Streptomyces padanus to Rhodococcus fascians. J Am Chem Soc 2008;130:1126-7
  • Federal Institute of Technology and University of Zurich, Switzerland. Preparation of aminoglycoside antibiotics targeting bacterial 16S ribosomal RNA. WO092690; 2008
  • Technion Research & Development Foundation, Haifa, Israel. Novel aminoglycosides and uses thereof in the treatment of genetic disorders. US0093418; 2009
  • Utah State University, North Logan, USA. New aminoglycosides: synthesis and use as antifungals. WO152202; 2009
  • University Joseph Fourier, Grenoble, France. Synthesis of novel neamine derivatives and use thereof as antibacterial agents. WO095588; 2009
  • Baussanne I, Bussiere A, Halder S, Synthesis and antimicrobial evaluation of amphiphilic neamine derivatives. J Med Chem 2010;53:119-27
  • Rybak MJ, Abate BJ, Kang SL, Prospective evaluation of the effect of an aminoglycoside dosing regimen on rates of observed nephrotoxicity and ototoxicity. Antimicrob Agents Chemother 1999;43:1549-55
  • Nicolau DP, Freeman CD, Belliveau PP, Experience with once-daily aminoglycoside program administered to 2,184 adult patients. Antimicrob Agents Chemother 1995;39:650-5
  • Kostrub CF, Diokno R, Aggen JB, Quantitative comparison of aminoglycoside nephrotoxicity in rats for effective screening and evaluation of new derivatives, and dosing rationales that minimize toxicity. Poster 1979, 19th ECCMID Conference; 16 – 19 May 2009; Helsinki, Finland
  • Tenover FC, Elvrum PM. Detection of two different kanamycin resistance genes in naturally occurring isolates of Campylobacter jejuni and Campylobacter coli. Antimicrob Agents Chemother 1988;32:1170-3
  • Maebashi K, Usui T, Hiraiwa Y, Synthesis and biological evaluation of TS2037, a novel aminoglycoside antibiotic. Abstract F-716, 44th ICAAC Conference; October 30 – November 2 2004; Washington, DC, USA
  • Eric Swayze, ISIS Pharmaceuticals; personal communication

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