Inhaled nitric oxide in cardiology

Bibliography

• FURCHGOTT RF, ZAWADZKI JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature (1980) 288(5789):373–376.
   PubMed Web of Science ®Google Scholar
• ••Seminal work outlining the importance ofthe endothelium in NO production.
   Google Scholar
• MONCADA S, PALMER RMJ, HIGGS EA: Nitric oxide: physiology, pathophysiology and pharmacology Pharmacol. Rev (1991) 43:109–143.
   Google Scholar
• ••An excellent review.
   Google Scholar
• ROSSAINT R, PISON U, GERLACH H, FALKE KJ: Inhaled nitric oxide: its effects on pulmonary circulation and airway smooth muscle cells. Eur. Heart j (1993) 14(Suppl. I):133–140.
   Google Scholar
• WEITZBERG E, LUNDBERG JO: Nonenzymatic nitric oxide production in humans. Nitric Oxide (1998) 2(1):1–7.
   PubMed Web of Science ®Google Scholar
• BRETT SJ, CHAMBERS J, BUSH A, ROSENTHAL M, EVANS TW: Pulmonary response of normal human subjects to inhaled vasodilator substances. an. Sci. (Colch) (1998) 95(5):621–627.
   PubMed Web of Science ®Google Scholar
• RIMAR S, GILLIS CN: Selective pulmonary vasodilation by inhaled nitric oxide is due to haemoglobin inactivation. Circulation (1993) 88(6):2884–2887.
   PubMed Web of Science ®Google Scholar
• •Important contributions to the understanding of NO inactivation.
   Google Scholar
• COLLINS P, BURMAN J, CHUNG H-I, FOX K: Haemoglobin inhibits endothelium dependent relaxation to acetylcholine in human coronary arteries in vivo. Circulation (1993) 87:80–85.
   PubMed Web of Science ®Google Scholar
• •Important contributions to the understanding of NO inactivation.
   Google Scholar
• IGNARRO LJ, LIPPTON H, EDWARDS JC et al.: Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates. j Pharmacol. Esp. Ther. (1981) 218:739–749.
   PubMed Web of Science ®Google Scholar
• TAMLER JS, SIMON DI, OSBORNE JA et al.: S-Nitrosylation of proteins with nitric oxide: synthesis and characterisation of biologically active compounds. Proc. Nati Acad. Sci. USA (1992) 89:444–448.
   PubMed Web of Science ®Google Scholar
• MARLEY R, PATEL RP, ORIE N, CEASER E, DARLEY-USMAR V, MOORE K: Formation of nanomolar concentrations of S- nitroso-albumin in human plasma by nitric oxide. Free Radic. Biol. Med. (2001) 31(5):688–696.
   PubMed Web of Science ®Google Scholar
• DELICONSTANTINOS G, VILLIOTOU V, STAVRIDES JC: Scavenging effects of haemoglobin and related heme containing compounds on nitric oxide, reactive oxidants and carcinogenic volatile nitrosocompounds of cigarette smoke. A new method for protection against the dangerous cigarette constituents. Anti-Cancer Res. (1994) 14(6B):2717–2726.
   Google Scholar
• WENNMALM A, BENTHIN G, EDLUND A et al.: Metabolism and excretion of nitric oxide in humans. An experimental and clinical study Circ. Res. (1993) 73(6):1121–1127.
   Google Scholar
• •Important contribution to the understanding of NO metabolism.
   Google Scholar
• YOSHIDA K, KASAMA K: Biotransformation of nitric oxide. Eriviron. Health Perspect (1987) 73:201–205.
   PubMed Web of Science ®Google Scholar
• WESTFELT UN, BENTHIN G, LUNDIN S, STENQVIST 0, WENNMALM A: Conversion of inhaled nitric oxide to nitrate in man. Br .j Pharmacol. (1995) 114(8):1621–1624.
   PubMedGoogle Scholar
• TSUKAHARA H, ISHIDA T, MAYUMI M: Gas-phase oxidation of nitric oxide: chemical kinetics and rate constant. Nitric Oxide (1999) 3(3):191–198.
   PubMed Web of Science ®Google Scholar
• SCHEDIN U, FROSTELL CG, GUSTAFSSON LE: Formation of nitrogen dioxide from nitric oxide and their measurement in clinically relevant circumstances. Br. j Ariaesth. (1999) 82(2):182–192.
   PubMed Web of Science ®Google Scholar
• SOKOL GM, VAN MEURS KP WRIGHT LL et al.: Nitrogen dioxide formation during inhaled nitric oxide therapy. CM]. Chem. (1999) 45(3):382–387.
   Google Scholar
• CUTHBERTSON BH, DELLINGER P, DYAR OJ et al.: UK guidelines for the use of inhaled nitric oxide therapy in adult ICUs. American-European Consensus Conference on ALI/ARDS. Intensive Care Med. (1997) 23(12):1212–1218.
   PubMed Web of Science ®Google Scholar
• ••A good summary of important issues in theadministration of INO.
   Google Scholar
• WESSEL DL, ADATIA I, THOMPSON JE, HICKEY PR: Delivery and monitoring of inhaled nitric oxide in patients with pulmonary hypertension. Crit. Care Med. (1994) 22(6):930–938.
   PubMed Web of Science ®Google Scholar
• MOURGEON E, LEVESQUE E, DUVEAU C et al.: Factors influencing indoor concentrations of nitric oxide in a Parisian intensive care unit. Am. j Respir: Grit. Care Med. (1997) 156(5):1692–1695.
   PubMed Web of Science ®Google Scholar
• ROBERTS JD, POLANER DM, LANG P, ZAPOL WM: Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet (1992) 340(8823):818–819.
   PubMed Web of Science ®Google Scholar
• KINSELLA JP, NEISH SR, SHAFFER E, ABMAN SH: Low-dose inhalation nitric oxide in persistent pulmonary hypertension of the newborn. Lancet (1992) 340(8823):819–820.
   PubMed Web of Science ®Google Scholar
• KIELER-JENSEN N, RICKSTEN SE, STENQVIST 0 etal.: Inhaled nitric oxide in the evaluation of heart transplant candidates with elevated pulmonary vascular resistance. j Heart Lung Transplant (1994) 13(3):366–375.
   Google Scholar
• •A good discussion of the effects of INO in heart failure.
   Google Scholar
• HAYWARD CS, ROGERS P, KEOGH AM, KELLY R, SPRATT PM, MACDONALD PS: Inhaled nitric oxide in cardiac failure: vascular versus ventricular effects.
   Google Scholar
• Cardiovasc. Pharmacol. (1996) 27(1):80–85.
   Google Scholar
• •A demonstration of dose response issues including NOx response.
   Google Scholar
• FULLERTON DA, JONES SD, JAGGERS J, PIEDALUE F, GROVER FL, MCINTYRE RC, JR.: Effective control of pulmonary vascular resistance with inhaled nitric oxide after cardiac operation. j Thorac. Cardiovasc. Surg. (1996) 111(4):753–762; discussion 762–753.
   Google Scholar
• PUYBASSET L, ROUBY JJ, MOURGEONE et al.: Inhaled nitric oxide in acute respiratory failure: dose-response curves. Intensive Care Med. (1994) 20(5):319–327.
   PubMed Web of Science ®Google Scholar
• LOWSON SM, RICH GF, MCARDLE PA, JAIDEV J, MORRIS GN: The response to varying concentrations of inhaled nitric oxide in patients with acute respiratory distress syndrome. Ariesth. Arialg. (1996) 82(3):574–581.
   PubMed Web of Science ®Google Scholar
• HAYWARD CS, ROGERS P, KEOGH AM, KELLY R, SPRATT PM, MACDONALD PS: Inhaled nitric oxide in cardiac failure: vascular versus ventricular effects.
   Google Scholar
• Cardiovasc. Pharmacol. (1996) 27(1):80–85.
   Google Scholar
• LOH E, STAMLER JS, HARE JM, LOS CALZO J, COLUCCI WS: Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction. Circulation (1994) 90:2780–2785.
   PubMed Web of Science ®Google Scholar
• •A good discussion of the effects of INO in heart failure.
   Google Scholar
• WILLIAMSON DJ, HAYWARD C, ROGERS P et al.: Acute hemodynamic responses to inhaled nitric oxide in patients with limited scleroderma and isolated pulmonary hypertension. Circulation (1996) 94(3):477–482.
   PubMed Web of Science ®Google Scholar
• MICHEL T, SMITH TW: Nitric oxide synthases and cardiovascular signalling. Am. Cardiol. (1993) 72:33C–38C.
   Google Scholar
• BALLIGAND J-L, UNGUREANU D, KELLY RA et al.: Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. j Chi]. Invest. (1993) 91:2314–2319.
   PubMed Web of Science ®Google Scholar
• BRADY AJB, WARREN JB, POOLE-WILSON PA, WILLIAMS TJ, HARDING SE: Nitric oxide attenuates cardiac myocyte contraction. kn. j Physiol. (1993) 265:H176–H182.
   Web of Science ®Google Scholar
• MOHAN E BRUTSAERT DL, SYS SU: Myocardial performance is modulated by interaction of cardiac endothelium derived nitric oxide and prostaglandins. Cardiovasc. Res. (1995) 29:637–640.
   PubMed Web of Science ®Google Scholar
• FINKEL MS, ODDIS CV, JACOB TD, WATKINS SC, HATTLER BG, SIMMONS RL: Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science (1992) 257:387–389.
   PubMed Web of Science ®Google Scholar
• HARE JM, LOH E, CREAGER MA, COLUCCI WS: Nitric oxide inhibits the positive inotropic response to 13-adrenergic stimulation in humans with left ventricular dysfunction. Circulation (1995) 92:2198–2203.
   PubMed Web of Science ®Google Scholar
• MOHAN E BRUTSAERT DL, PAULUS WJ, SYS SU: Myocardial contractile response to nitric oxide and cGMP. Circulation (1996) 93:1223–1229.
   PubMed Web of Science ®Google Scholar
• PRECKEL B, KOJDA G, SCHLACK W et al.: Inotropic effects of glyceryl trinitrate and spontaneous NO donors in the dog heart. Circulation (1997) 96:2675–2682.
   PubMed Web of Science ®Google Scholar
• STAMLER JS, JARAKI 0, OSBORNE J et al.: Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc. Nati Acad. Sci. USA (1992) 89:7674–7677.
   Google Scholar
• PEPKE-ZABA J, HIGENBOTTAM TW, DINH-XUAN AT, STONED, WALLWORK J: Inhaled nitric oxide as a cause of selective pulmonary vasodilatation in pulmonary hypertension. Lancet (1991) 338(8776):1173–1174.
   PubMed Web of Science ®Google Scholar
• •The first clinical reports of INO.
   Google Scholar
• FROSTELL C, FRATACCI MD, WAIN JC, JONES R, ZAPOL WM: Inhaled nitric oxide. A selective pulmonary vasodilator reversing hypoxic pulmonary vasoconstriction. Circulation (1991) 83(6):2038–2047.
   Google Scholar
• •The first clinical reports of INO.
   Google Scholar
• BRADY TC, CRAPO JD, MERCER RR: Nitric oxide inhalation transiently elevates pulmonary levels of cGMP, iNOS mRNA, and TNF-alpha. kn. I Physiol. (1998) 275(3 Pt 1)1509–515.
   Google Scholar
• GERLACH H, PAPPERT D, LEWANDOWSKI K, ROSSAINT R, FALKE KJ: Long-term inhalation with evaluated low doses of nitric oxide for selective improvement of oxygenation in patients with adult respiratory distress syndrome. Intensive Care Med. (1993) 19(8):443–449.
   PubMed Web of Science ®Google Scholar
• MILLER OI, TANG SF, KEECH A, CELERMAJER DS: Rebound pulmonary hypertension on withdrawal from inhaled nitric oxide. Lancet (1995) 346(8966):51–52.
   PubMed Web of Science ®Google Scholar
• ATZ AM, ADATIA I, WESSEL DL: Rebound pulmonary hypertension after inhalation of nitric oxide. Ann. Thorac. Surg. (1996) 62(6):1759–1764.
   PubMed Web of Science ®Google Scholar
• CUETO E, LOPEZ-HERCE J, SANCHEZ A, CARRILLO A: Life-threatening effects of discontinuing inhaled nitric oxide in children. Acta PaedMtr. (1997) 86(12):1337–1339.
   PubMed Web of Science ®Google Scholar
• CHRISTENSON J, LAVOIE A, M OC, BHORADE S, POHLMAN A, HALL JB: The incidence and pathogenesis of cardiopulmonary deterioration after abrupt withdrawal of inhaled nitric oxide. Am. Respir: Crit. Care Med. (2000) 161(5):1443–1449.
   PubMed Web of Science ®Google Scholar
• GIRARD C, DURAND PG, VEDRINNE C et al.: Case 4-1993. Inhaled nitric oxide for right ventricular failure after heart transplantation. j Cardiothorac. Vasc. Arresth. (1993) 7(4):481–485.
   PubMedGoogle Scholar
• OKA M, OHNISHI M, TAKAHASHI H et al.: Altered vasoreactivity in lungs isolated from rats exposed to nitric oxide gas. Am. Physiol. (1996) 271(3 Pt 1):L419–L424.
   Google Scholar
• BUGA GM, GRISCAVAGE JM, ROGERS NE, IGNARRO LJ: Negative feedback regulation of endothelial cell function by nitric oxide. Circ. Res. (1993) 73(5):808–812.
   PubMed Web of Science ®Google Scholar
• ROOS CM, FRANK DU, XUE C, JOHNS RA, RICH GF: Chronic inhaled nitric oxide: effects on pulmonary vascular endothelial function and pathology in rats. j Appl. Physiol. (1996) 80(1):252–260.
   PubMed Web of Science ®Google Scholar
• FRANK DU, HORSTMAN DJ, MORRIS GN, JOHNS RA, RICH GF: Regulation of the endogenous NO pathway by prolonged inhaled NO in rats. I Appl. Physiol. (1998) 85(3):1070–1078.
   PubMed Web of Science ®Google Scholar
• SHEEHY AM, BURSON MA, BLACK SM: Nitric oxide exposure inhibits endothelial NOS activity but not gene expression: a role for superoxide. Am. j Physiol. (1998) 274(5 Pt 1):L833–L841.
   Google Scholar
• DOTSCH J, DEMIRAKCA S, ZEPF K, HANZE J, PARIDA S, RASCHER W: Recovery from withdrawal of inhaled nitric oxide and kinetics of nitric oxide-induced inhibition of nitric oxide synthase activity in vitro. Intensive Care Med. (2000) 26(3)330–335.
   Google Scholar
• HANSON KA, ZIEGLER JW, RYBALKIN SD, MILLER JW, ABMAN SH, CLARKE WR: Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity. Am. I Physiol. (1998) 275(5 Pt 1):L931–L941.
   Google Scholar
• IVY DD, KINSELLA JP, ZIEGLER JW, ABMAN SH: Dipyridamole attenuates rebound pulmonary hypertension after inhaled nitric oxide withdrawal in postoperative congenital heart disease. Thorac. Cardiovasc. Surg. (1998) 115(4):875–882.
   Web of Science ®Google Scholar
• GIRARD C, FARGNOLI JM, GODIN-RIBUOT D et al.: Inhaled nitric oxide: effects on hemodynamics, myocardial contractility, and regional blood flow in dogs with mechanically induced pulmonary artery hypertension. I Heart Lung Transplant (1996) 15(7):700–708.
   PubMed Web of Science ®Google Scholar
• KRASUSKI RA, WARNER JJ, WANG A, HARRISON JK, TAPSON VF, BASHORE TM: Inhaled nitric oxide selectively dilates pulmonary vasculature in adult patients with pulmonary hypertension, irrespective of etiology. I Am. Coll. Cardiol. (2000) 36(7):2204–2211.
   PubMed Web of Science ®Google Scholar
• SITBON 0, HUMBERT M, JAGOT JL et al.: Inhaled nitric oxide as a screening agent for safely identifying responders to oral calcium-channel blockers in primary pulmonary hypertension. Eur. Respir: (1998) 12(2):265–270.
   Google Scholar
• RICCIARDI MJ, KNIGHT BP, MARTINEZ FJ, RUBENFIRE M: Inhaled nitric oxide in primary pulmonary hypertension: a safe and effective agent for predicting response to nifedipine. J Am. Coll. Cardiol. (1998) 32(4):1068–1073.
   PubMed Web of Science ®Google Scholar
• •A particular role for acute INO in defining chronic therapies for pulmonary hypertension.
   Google Scholar
• SITBON 0, BRENOT F, DENJEAN A et al.: Inhaled nitric oxide as a screening vasodilator agent in primary pulmonary hypertension. A dose-response study and comparison with prostacyclin. Am. I Respir: Grit. Care Med. (1995) 151(2 Pt 1):384–389.
   Google Scholar
• PARSONS S, CELERMAJER D, SAVIDIS E, MILLER 0, YOUNG I: The effect of inhaled nitric oxide on 6-minute walk distance in patients with pulmonary hypertension. Chest (1998) 114\(Suppl. 1):70S–72S.
   Google Scholar
• HASUDA T, SATOH T, SHIMOUCHI A etal.: Improvement in exercise capacity with nitric oxide inhalation in patients with precapillary pulmonary hypertension. Circulation (2000 May 2) 101(17):2066–2070.
   Google Scholar
• SNELL GI, SALAMONSEN RE BERGIN E ESMORE DS, KHAN S, WILLIAMS TJ: Inhaled nitric oxide used as a bridge to heart-lung transplantation in a patient with end-stage pulmonary hypertension. Am. I Respir. Grit. Care Med. (1995) 151(4):1263–1266.
   PubMed Web of Science ®Google Scholar
• CHANNICK RN, NEWHART JW, JOHNSON FW et al.: Pulsed delivery of inhaled nitric oxide to patients with primary pulmonary hypertension: an ambulatory delivery system and initial clinical tests. Chest (1996) 109(6):1545–1549.
   PubMed Web of Science ®Google Scholar
• MATSUMOTO A, MOMOMURA S, HIRATA Y, AOYAGI T, SUGIURA S, OMATA M: Inhaled nitric oxide and exercise capacity in congestive heart failure. Lancet (1997) 349(9057):999–1000.
   PubMed Web of Science ®Google Scholar
• PRENDERGAST B, SCOTT DH, MANKAD PS: Beneficial effects of inhaled nitric oxide in hypoxaemic patients after coronary artery bypass surgery. Eur. Cardiothorac. Surg. (1998) 14(5):488–493.
   PubMed Web of Science ®Google Scholar
• MATSUMOTO A, MOMOMURA S, SUGIURA S et al.: Effect of inhaled nitric oxide on gas exchange in patients with congestive heart failure. A randomized, controlled trial. Ann. Intern. Med. (1999) 130(1):40–44.
   PubMed Web of Science ®Google Scholar
• SPEZIALE G, DE BIASE L, DE VINCENTIS G et al: Inhaled nitric oxide in patients with severe heart failure: changes in lung perfusion and ventilation detected using scintigraphy. Thorac. Cardiovasc. Surg. (1996) 44(1):35–39.
   PubMed Web of Science ®Google Scholar
• YAHAGI N, KUMON K, TANIGAMI H et al.: Cardiac surgery and inhaled nitric oxide: indication and follow-up (2-4 years). Artif Organs (1998) 22(10):886–891.
   PubMed Web of Science ®Google Scholar
• PRENDERGAST B, SCOTT DH, MANKAD PS: Beneficial effects of inhaled nitric oxide in hypoxaemic patients after coronary artery bypass surgery. Eur. Cardiothorac. Surg. (1998) 14(5):488–493.
   PubMed Web of Science ®Google Scholar
• LINDBERG L, LARSSON A, STEEN S, OLSSON SG, NORDSTROM L: Nitric oxide gives maximal response after coronary artery bypass surgery. I Cardiothorac. Vasc. Ariesth. (1994) 8(2):182–187.
   PubMedGoogle Scholar
• CARMONA MJ, AULER JO, JR.: Effects of inhaled nitric oxide on respiratory system mechanics, hemodynamics, and gas exchange after cardiac surgery. I Cardiothorac. Vasc. Ariesth. (1998) 12(2):157–161.
   Google Scholar
• DOWNING SW, EDMUNDS LH, JR.: Release of vasoactive substances during cardiopulmonary bypass. Ann. Thorac. Surg. (1992) 54(6):1236–1243.
   Google Scholar
• BECK JR, MONGERO LB, KROSLOWITZ RIVI et al.: Inhaled nitric oxide improves hemodynamics in patients with acute pulmonary hypertension after high-risk cardiac surgery. Perfusion (1999) 14(1):37–42.
   PubMed Web of Science ®Google Scholar
• RAJEK A, PERNERSTORFER T, KASTNER J et al: Inhaled nitric oxide reduces pulmonary vascular resistance more than prostaglandin E(1) during heart transplantation. Ariesth. Arialg. (2000) 90(3):523–530.
   PubMed Web of Science ®Google Scholar
• WESSEL DL, ADATIA I, GIGLIA TM, THOMPSON JE, KULIK TJ: Use of inhaled nitric oxide and acetylcholine in the evaluation of pulmonary hypertension and endothelial function after cardiopulmonary bypass. Circulation (1993) 88(5 Pt 1):2128–2138.
   Google Scholar
• ••An important paper demonstrating thatpulmonary endothelial dysfunction contributes to postoperative pulmonary hypotension.
   Google Scholar
• BEGHETTI M, SILKOFF PE, CARAMORI M, HOLTBY HM, SLUTSKY AS, ADATIA I: Decreased exhaled nitric oxide may be a marker of cardiopulmonary bypass-induced injury. Ann. Thorac. Surg. (1998) 66(2):532–534.
   PubMed Web of Science ®Google Scholar
• SCHULZE-NEICK I, PENNY DJ, RIGBY ML et al: L-arginine and substance P reverse the pulmonary endothelial dysfunction caused by congenital heart surgery. Circulation (1999) 100(7):749–755.
   PubMed Web of Science ®Google Scholar
• GIRARD C, LEHOT JJ, PANNETIER JC, FILLEY S, FFRENCH P, ESTANOVE S: Inhaled nitric oxide after mitral valve replacement in patients with chronic pulmonary artery hypertension. Anesthesiology (1992) 77(5):880–883.
   PubMed Web of Science ®Google Scholar
• RICH GF, MURPHY GD, JR., ROOS CM, JOHNS RA: Inhaled nitric oxide. Selective pulmonary vasodilation in cardiac surgical patients. Anesthesiology (1993) 78(6):1028–1035.
   Google Scholar
• SNOW DJ, GRAY SJ, GHOSH S et al.: Inhaled nitric oxide in patients with normal and increased pulmonary vascular resistance after cardiac surgery. Br. I Ariaesth. (1994) 72(2):185–189.
   PubMed Web of Science ®Google Scholar
• FULLERTON DA, JAGGERS J, WOLLMERING MM, PIEDALUE GROVER FL, MCINTYRE RC, JR.: Variable response to inhaled nitric oxide after cardiac surgery. Ann. Thorac. Surg. (1997) 63(5):1251–1256.
   Google Scholar
• MAHONEY PD, LOH E, BLITZ LR, HERRMANN HC: Hemodynamic effects of inhaled nitric oxide in women with mitral stenosis and pulmonary hypertension. Am. Cardiol (2001) 87(2):188–192.
   PubMed Web of Science ®Google Scholar
• FOUBERT L, LATIMER R, ODURO A et al.: Use of inhaled nitric oxide to reduce pulmonary hypertension after heart transplantation. I Cardiothorac. Vasc. Ariesth. (1993) 7(5):640–641.
   PubMedGoogle Scholar
• AULER JR JO, CARMONA MJ, BOCCHI EA et al: Low doses of inhaled nitric oxide in heart transplant recipients. I Heart Lung Transplant (1996) 15(5):443–450.
   PubMed Web of Science ®Google Scholar
• CARRIER M, BLAISE G, BELISLE S et al: Nitric oxide inhalation in the treatment of primary graft failure following heart transplantation. I Heart Lung Transplant (1999) 18(7):664–667.
   PubMed Web of Science ®Google Scholar
• KIELER-JENSEN N, LUNDIN S, RICKSTEN SE: Vasodilator therapy after heart transplantation: effects of inhaled nitric oxide and intravenous prostacyclin, prostaglandin El, and sodium nitroprusside. Heart Lung Transplant (1995) 14(3):436–443.
   PubMed Web of Science ®Google Scholar
• MILLER 01, CELERMAJER DS, DEANFIELD JE, MACRAE DJ: Very-low-dose inhaled nitric oxide: a selective pulmonary vasodilator after operations for congenital heart disease. I Thorac. Cardiovasc. Surg. (1994) 108(3):487–494.
   PubMed Web of Science ®Google Scholar
• MATSUI J, YAHAGI N, KUMON K etal.: Effects of inhaled nitric oxide on postoperative pulmonary circulation in patients with congenital heart disease. Artif Organs (1997) 21(1):17–20.
   Google Scholar
• ROBERTS JD, JR., LANG P, BIGATELLOLM, VLAHAKES GJ, ZAPOL WM: Inhaled nitric oxide in congenital heart disease. Circulation (1993) 87(2):447–453.
   PubMed Web of Science ®Google Scholar
• JOURNOIS D, POUARD P, MAURIAT P, MALHERE T, VOUHE P, SAFRAN D: Inhaled nitric oxide as a therapy for pulmonary hypertension after operations for congenital heart defects. j Thorac. Cardiovasc. Surg. (1994) 107(4):1129–1135.
   PubMed Web of Science ®Google Scholar
• DAY RW, HAWKINS JA, MCGOUGH EC, CREZEE KL, ORSMOND GS: Randomized controlled study of inhaled nitric oxide after operation for congenital heart disease. Ann. Thorac. Surg. (2000) 69(6):1907–1912.
   PubMed Web of Science ®Google Scholar
• BEGHETTI M, MORRIS K, COX P, BOHN D, ADATIA I: Inhaled nitric oxide differentiates pulmonary vasospasm from vascular obstruction after surgery for congenital heart disease. Intensive Care Med. (1999) 25(10):1126–1130.
   PubMed Web of Science ®Google Scholar
• ADATIA I, PERRY S, LANDZBERG M, MO ORE E THOMPSON JE, WESSEL DL: Inhaled nitric oxide and hemodynamic evaluation of patients with pulmonary hypertension before transplantation. j Am. Coll. Cardiol. (1995) 25(7):1656–1664.
   PubMed Web of Science ®Google Scholar
• BOCCHI EA, BACAL F, AULER JUNIOR JO, CARMONE MJ, BELLOTTI G, PILEGGI F: Inhaled nitric oxide leading to pulmonary edema in stable severe heart failure. Am. J. Cardiol (1994) 74(1):70–72.
   PubMed Web of Science ®Google Scholar
• DICKSTEIN ML, BURKHOFF D: A theoretic analysis of the effect of pulmonary vasodilation on pulmonary venous pressure: implications for inhaled nitric oxide therapy. Heart Lung Transplant (1996) 15(7):715–721.
   PubMed Web of Science ®Google Scholar
• HAYWARD CS, KALNINS WV, ROGERS E FENELEY MP, MACDONALD PS, KELLY RP: Left ventricular chamber function during inhaled nitric oxide in patients with dilated cardiomyopathy. Cardiovasc. Pharmacol (1999) 34(5):749–754.
   PubMed Web of Science ®Google Scholar
• MORAES DL, COLUCCI WS, GIVERTZ MM: Secondary pulmonary hypertension in chronic heart failure: the role of the endothelium in pathophysiology and management. Circulation (2000) 102(14):1718–1723.
   PubMed Web of Science ®Google Scholar
• CHEIFETZ IM, CRAIG DM, KERN FH et al.: Nitric oxide improves transpulmonary vascular mechanics but does not change intrinsic right ventricular contractility in an acute respiratory distress syndrome model with permissive hypercapnia. Ctit. Care Med. (1996) 24(9):1554–1561.
   PubMed Web of Science ®Google Scholar
• HILLMAN ND, CHEIFETZ IM, CRAIG DM, SMITH PK, UNGERLEIDER RIVI, MELIONES JN: Inhaled nitric oxide, right ventricular efficiency, and pulmonary vascular mechanics: selective vasodilation of small pulmonary vessels during hypoxic pulmonary vasoconstriction. I Thorac. Cardiovasc. Surg. (1997) 113(6):1006–1013.
   PubMed Web of Science ®Google Scholar
• OFFNER PJ, OGURA H, JORDAN BS, PRUITT BA, JR., CIOFFI WG: Effects of inhaled nitric oxide on right ventricular function in endotoxin shock. j Trauma (1995) 39(2):179–185; discussion 185–176.
   Google Scholar
• KOELLING TM, KIRMSE M, DI SALVO TG, DEC GW, ZAPOL WM, SEMIGRAN MJ: Inhaled nitric oxide improves exercise capacity in patients with severe heart failure and right ventricular dysfunction. Am. Cardiol (1998) 81(12):1494–1497.
   PubMed Web of Science ®Google Scholar
• BHORADE S, CHRISTENSON J, M OC, LAVOIE A, POHLMAN A, HALL JB: Response to inhaled nitric oxide in patients with acute right heart syndrome. Am. Respir: Grit. Care Med. (1999) 159(2):571–579.
   PubMed Web of Science ®Google Scholar
• FRAZIER OH, ROSE EA, MACMANUS Q et al: Multicenter clinical evaluation of the HeartMate 1000 IP left ventricular assist device. Ann. Thorac. Surg. (1992) 53(6):1080–1090.
   PubMed Web of Science ®Google Scholar
• YAHAGI N, KUMON K, NAKATANI T et al.: Inhaled nitric oxide for the management of acute right ventricular failure in patients with a left ventricular assist system. Aral: Organs (1995) 19(6):557–558.
   PubMed Web of Science ®Google Scholar
• MACDONALD PS, KEOGH A, MUNDY J et al: Adjunctive use of inhaled nitric oxide during implantation of a left ventricular assist device. I Heart Lung Transplant (1998) 17(3):312–316.
   PubMed Web of Science ®Google Scholar
• CHANG JC, SAWA Y, OHTAKE S et al: Hemodynamic effect of inhaled nitric oxide in dilated cardiomyopathy patients on LVAD support. Asaio J. (1997) 43(5):M418–M421.
   PubMed Web of Science ®Google Scholar
• ARGENZIANO M, CHOUDHRI AF, MOAZAMI N etal.: Randomized, double-blind trial of inhaled nitric oxide in LVAD recipients with pulmonary hypertension. Ann. Thorac. Surg. (1998) 65(2):340–345.
   Google Scholar
• HARE JM, SHERNAN SK, BODY SC, GRAYDON E, COLUCCI WS, COUPER GS: Influence of inhaled nitric oxide on systemic flow and ventricular filling pressure in patients receiving mechanical circulatory assistance. Circulation (1997) 95(9):2250–2253.
   PubMed Web of Science ®Google Scholar
• •A good demonstration of the effect of INO on ventricular loading and haemodynamics in the presence of impaired LV function.
   Google Scholar
• BRILLI RJ, KRAFTE-JACOBS B, SMITH DJ, PASSERINI D, MOORE L, BALLARD ET: Aerosolization of novel nitric oxide donors selectively reduce pulmonary hypertension. Grit. Care Med. (1998) 26(8):1390–1396.
   PubMed Web of Science ®Google Scholar
• AL-ALAIYAN S, AL-OMRAN A, DYER D: The use of phosphodiesterase inhibitor (dipyridamole) to wean from inhaled nitric oxide. Intensive Care Med. (1996) 22(10):1093–1095.
   PubMed Web of Science ®Google Scholar
• ICHINOSE F, ADRIE C, HURFORD WE, BLOCH KD, ZAPOL WM: Selective pulmonary vasodilation induced by aerosolized zaprinast. Anesthesiology (1998) 88(2):410–416.
   PubMed Web of Science ®Google Scholar
• ZHAO L, MASON NA, MORRELL NW et al.: Sildenafil inhibits hypoxia-induced pulmonary hypertension. Circulation (2001) 104(4):424–428.
   PubMed Web of Science ®Google Scholar
• MACHHERNDL S, KNEUSSL M, BAUMGARTNER H etal.: Long-term treatment of pulmonary hypertension with aerosolised iloprost. Eur. Respir. j (2001) 17(1):8–13.
   Google Scholar
• HOEPER MM, OLSCHEWSKI H, GHOFRANI HA et al: A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. German PPH study group. I Am. Coll. Cardiol (2000) 35(1):176–182.
   PubMed Web of Science ®Google Scholar
• HARALDSSON A, KIELER-JENSEN N, NATHORST-WESTFELT U, BERGH CH, RICKSTEN SE: Comparison of inhaled nitric oxide and inhaled aerosolized prostacyclin in the evaluation of heart transplant candidates with elevated pulmonary vascular resistance. Chest (1998) 114(3):780–786.
   PubMed Web of Science ®Google Scholar
• HOEPER MM, SCHWARZE M, EHLERDING S et al.: Long-term treatment of primary pulmonary hypertension with aerosolized iloprost, a prostacyclin analogue. N. Engl. J. Med. (2000) 342(25):1866–1870.
   PubMed Web of Science ®Google Scholar
• ••An important new therapy in themanagement of pulmonary hypertension.
   Google Scholar
• BARST RJ, SIMONNEAU G, RICH S, BLACKBURN SD, NAEIJE R, RUBIN LJ: Efficacy and safety of chronic subcutaneous infusion UT-15 in pulmonary arterial hypertension. Circulation (2000) 102(18):II–100–101.
   Web of Science ®Google Scholar
• CHANNICK RN, RUBIN LJ, SIMONNEAU G et al.: Bosentan, a dual endothelin receptor antagonist, improves exercise capacity and hemodynamics in patients with pulmonary arterial hypertension: results of a double blind, randomized, placebo controlled trial. Circulation (2000) 102(18):II–100.
   Web of Science ®Google Scholar
• RADOMSKI MW, PALMER RM, MONCADA S: Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet (1987) 2(8567):1057–1058.
   PubMed Web of Science ®Google Scholar
• HOGMAN M, FROSTELL C, ARNBERG H, HEDENSTIERNA G: Bleeding time prolongation and NO inhalation. Lancet (1993) 341(8860:1664–1665.
   PubMedGoogle Scholar
• GRIES A, HERR A, MOTSCH J et al: Randomized, placebo-controlled, blinded and cross-matched study on the antiplatelet effect of inhaled nitric oxide in healthy volunteers. Thromb. Haemost. (2000) 83(2):309–315.
   PubMed Web of Science ®Google Scholar
• ALBERT J, NORMAN M, WALLEN NH, FROSTELL C, HJEMDAHL P: Inhaled nitric oxide does not influence bleeding time or platelet function in healthy volunteers. Eur. j Chit. Invest. (1999) 29(11):953–959.
   PubMed Web of Science ®Google Scholar
• MORO MA, DARLEY-USMAR VM, GOODWIN DA et al: Paradoxical fate and biological action of peroxynitrite on human platelets. Proc. Natl. Acad. Li. USA (1994) 91(14):6702–6706.
   PubMed Web of Science ®Google Scholar
• ADRIE C, BLOCH KD, MORENO PR et al.: Inhaled nitric oxide increases coronary artery patency after thrombolysis. Circulation (1996) 94(8):1919–1926.
   PubMed Web of Science ®Google Scholar
• FOX-ROBICHAUD A, PAYNE D, HASAN SU et al: Inhaled NO as a viable antiadhesive therapy for ischemiaireperfusion injury of distal microvascular beds. j Chit. Invest. (1998) 101(10:2497–2505.
   PubMedGoogle Scholar
• MACDONALD P, MUNDY J, ROGERS P et al.: Successful treatment of life-threatening acute reperfusion injury after lung transplantation with inhaled nitric oxide. _J. Thome. Cardiovasc. Surg. (1995) 110(3):861–863.
   PubMed Web of Science ®Google Scholar
• MURAKAMI S, BACHA EA, HERVE P et al.: Prevention of reperfusion injury by inhaled nitric oxide in lungs harvested from non-heart-beating donors. Paris-Sud University Lung Transplantation Group. Ann. Thome. Surg. (1996) 62(6):1632–1638.
   PubMed Web of Science ®Google Scholar