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Miscellaneous

A small-molecule antagonist of virion assembly

Pages 1767-1770 | Published online: 24 Feb 2005

Bibliography

  • KANAMOTO T, KASHIWADA Y, KANBARA K et al.: Anti-human immunodeficiency virus activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation. Antimicrob. Agents Chernother (2001) 45:1225–1230.
  • EVERS M, POUJADE C, SOLER F et al.:Betulinic acid derivatives: a new class of human immunodeficiency virus type 1 specific inhibitors with a new mode of action. J. Med. Chem. (1996) 39(5):1056–1068.
  • LABROSSE B, PLESKOFF 0, SQL N, JONES C, HENIN Y, ALIZON M: Resistance to a drug blocking human immunodeficiency virus type 1 entry (RPR103611) is conferred by mutations in gp4l.j Viral. (1997) 71(11):8230–8236.
  • MAYAUX JF, BOUSSEAU A, PAUWELS R et al.: Triterpene derivatives that block entry of human immunodeficiency virus type 1 into cells. Proc. Natl. Acad. Sci. USA (1994) 91(9):3564–3568.
  • SOLER E POUJADE C, EVERS M et al.: Betulinic acid derivatives: a new class of specific inhibitors of human immunodeficiency virus type 1 entry. j. Med. Chem. (1996) 39(5):1069–1083.
  • XU HX, ZENG FQ, WAN M, SIM KY: Anti-HIV triterpene acids from Geum japonicum. j Nat. Prod. (1996) 59(7):643–645.
  • PENGSUPARP T, CAI L, FONG HH et al.: Pentacyclic triterpenes derived from Maprounea africana are potent inhibitors of HIV-1 reverse transcriptase. j Nat. Prod (1994) 57(3):415–418.
  • DE CLERCQ E: Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection. Med. Res. Rev (2000) 20(5):323–349.
  • COSTANTINI P, ACOTOT EJ, DECAUDIN D, KROEMER G: Mitochondrion as a novel target of anticancer chemotherapy. j. Natl. Cancer Inst. (2000) 92(13):1042–1053.
  • FULDA S, SCAFFIDI C, SUSIN SA et al.: Activation of mitochondria and release of mitochondrial apoptogenic factors by betulinic acid. j. Biol. Chem. (1998) 273(51):33942–33948.
  • KIM DS, PEZZUTO JM, PISHA E: Synthesis of betulinic acid derivatives with activity against human melanoma. Bioorg. Med. Chem. Lett. (1998) 8(13):1707–1712.
  • SALTI GI, KICHINA JV, DAS GUPTA TK et al.: Betulinic acid reduces ultraviolet-C-induced DNA breakage in congenital melanocytic naeval cells: evidence for a potential role as a chemopreventive agent. Melanoma Res. (2001) 11(2):99–104.
  • MELZIG, ME BORMANN H: Betulinic acid inhibits aminopeptidase N activity. Planta Med. (1998) 64(7):655–657.
  • FULDA S, JEREMIAS I, PIETSCH T, DEBATIN KM: Betulinic acid: a new chemotherapeutic agent in the treatment of neuroectodermal tumors. Kiln. Padiati: (1999) 211(4):319–22.
  • FULDA S, SUSIN SA, KROEMER G, DEBATIN KM: Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. Cancer Res. (1998) 58(19)4453–4460.
  • SCHMIDT ML, KUZMANOFF KL, LING-INDECK L, PEZZUTO JM: Betulinic acid induces apoptosis in human neuroblastoma cell lines. Eur. j Cancer (1997) 33(12):2007–2010.
  • SELZER E, PIMENTEL E, WACHECK V et al: Effects of betulinic acid alone and in combination with irradiation in human melanoma cells. (200) j Invest. Dermatol. 114(5):935–40.
  • FULDA S, JEREMIAS I, STEINER HH, PIETSCH T, DEBATIN KM: Betulinic acid: a new cytotoxic agent against malignant brain-tumor cells. Irm j Cancer (1999) 82(3):435–441.
  • WICK W, GRIMMEL C, WAGENKNECHT B et al.: Betulinic acid-induced apoptosis in glioma cells: A sequential requirement for new protein synthesis, formation of reactive oxygen species, and caspase processing. Pharmacol. Exp. Ther. (1999) 289(3):1306–1312.
  • MA J, STARCK SR, HECHT SM: DNA polymerase beta inhibitors from Tetracera boiviniana. j Nat. Prod (1999) 62(12):1660–1663.
  • SYROVETS T, BUCHELE B, GEDIG E et al.: Acetyl-boswellic acids are novel catalytic inhibitors of human topoisomerases I and IIa. Mal Pharmacol (2000) 58(1):71–81.
  • YASUKAWA K, TAKIDO M, MATSUMOTO T, TAKEUCHI M, NAKAGAWA S: Sterol and triterpene derivatives from plants inhibit the effects of a tumor promoter, and sitosterol and betulinic acid inhibit tumor formation in mouse skin two-stage carcinogenesis. Oncology (1991) 48(1):72–76.
  • RIEBER M, STRASBERG RIEBER M: Induction of p53 without increase in p21WAF1 in betulinic acid-mediated cell death is preferential for human metastatic melanoma. DNA Cell Biol. (1998) 17(5):399–406.
  • PISHA E., CHAI H, LEE IS et al.: Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. (1995) Nat. Med. 1(10):1046–1051.
  • UDEANI GO, ZHAO GM, GEUN SHIN Y et al.: Pharmacokinetics and tissue distribution of betulinic acid in CD-1 mice. Biopharm. Drug Dispos. (1999) 20(8):379–383.
  • HOLZ-SMITH SL, SUN IC, JIN L, MATTHEWS TJ, LEE KH, CHEN CH: Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative 1C9 564. Antimicrob. Agents Chemother. (2001) 45(1):60–66.
  • KASHIWADA Y, HASHIMOTO F, COSENTINO LM, CHEN CH, GARRETT PE, LEE KH: Betulinic acid and dihydrobetulinic acid derivatives as potent anti-HIV agents. j Med. Chem. (1996) 39(5):1016–1017.

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