Glial modulators: a novel pharmacological approach to altering the behavioral effects of abused substances

Bibliography

• Pelvig DP, Pakkenberg H, Stark AK, Pakkenberg B. Neocortical glial cell numbers in human brains. Neurobiol Aging 2008;29:1754-62
   PubMed Web of Science ®Google Scholar
• Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996;19:312-18
   PubMed Web of Science ®Google Scholar
• Nakajima K, Kohsaka S. Functional roles of microglia in the brain. Neurosci Res 1993;17:187-203
   PubMed Web of Science ®Google Scholar
• Stoll G, Jander S. The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 1999;58:233-47
   PubMed Web of Science ®Google Scholar
• Verkhratsky A, Kettenman H. Calcium signaling in glial cells. Trends Neurosci 1996;19:346-52
   PubMed Web of Science ®Google Scholar
• Okimura Y, Tanno H, Fukuda K, Reactive astrocytes in acute stage after experimental brain injury: relationship to extravasated plasma protein and expression of heat shock protein. J Neurotrauma 1996;13:385-93
   PubMed Web of Science ®Google Scholar
• Svendsen CN. Neurobiology: The amazing astrocyte. Nature 2002;417:29-32
   PubMed Web of Science ®Google Scholar
• Ullian EM, Sapperstein SK, Christopherson KS, Barres BA. Control of synapse number by glia. Science 2001;291:657-61
   PubMed Web of Science ®Google Scholar
• Nakajima K, Kohsaka S. Microglia: activation and their significance in the central nervous system. J Biochem 2001;130:169-75
   PubMed Web of Science ®Google Scholar
• Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Results from the 2007 National Survey on Drug Use and Health: National Findings. Rockville, MD, 2008a (NSDUH Series H-34, DHHS Publication No. SMA 08-4343)
   Google Scholar
• Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Drug Abuse Warning Network, 2006: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD, 2008b (DAWN Series D-30, DHHS Publication No. SMA 08-4339)
   Google Scholar
• Cooper ZD, Truong YN, Shi YG, Woods JH. Morphine deprivation increases self-administration of the fast- and short-acting mu-opioid receptor agonist remifentanil in the rat. J Pharmacol Exp Ther 2008;326:920-9
   PubMed Web of Science ®Google Scholar
• Angst MS, Clark JD. Opioid-induced hyperalgesia: a qualitative systematic review. Anesthesiology 2006;104:570-87
   PubMed Web of Science ®Google Scholar
• Watkins LR, Hutchinson MR, Johnston IN, Maier SF. Glia: novel counterregulators of opioid analgesia. Trends Neurosci 2005;28:661-9
   PubMed Web of Science ®Google Scholar
• Eng LF. Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes. J Neuroimmunol 1985;8:203-14
   PubMed Web of Science ®Google Scholar
• Beitner-Johnson D, Guitart X, Nestler EJ. Glial fibrillary acidic protein and the mesolimbic dopamine system: regulation by chronic morphine and Lewis-Fischer strain differences in the rat ventral tegmental area. J Neurochem 1993;61:1766-73
   PubMed Web of Science ®Google Scholar
• Garrido E, Perez-Garcia C, Alguacil LF, Diez-Fernandez C. The alpha2-adrenoceptor antagonist yohimbine reduces glial fibrillary acidic protein upregulation induced by chronic morphine administration. Neurosci Lett 2005;383:141-4
   PubMed Web of Science ®Google Scholar
• Song P, Zhao ZQ. The involvement of glial cells in the development of morphine tolerance. Neurosci Res 2001;39:281-6
   PubMed Web of Science ®Google Scholar
• Rasmussen K, Beitner-Johnson DB, Krystal JH, Opiate withdrawal and the rat locus coeruleus: behavioral, electrophysiological, and biochemical correlates. J Neurosci 1990;10:2308-17
   PubMed Web of Science ®Google Scholar
• Marie-Claire C, Courtin C, Roques BP, Noble F. Cytoskeletal genes regulation by chronic morphine treatment in rat striatum. Neuropsychopharmacology 2004;29:2208-15
   PubMed Web of Science ®Google Scholar
• Koob GF. Neural mechanisms of drug reinforcement. Ann N Y Acad Sci 1992;654:171-91
   PubMed Web of Science ®Google Scholar
• Narita M, Miyatake M, Narita M, Direct evidence of astrocytic modulation in the development of rewarding effects induced by drugs of abuse. Neuropsychopharmacology 2006;31:2476-88
   PubMed Web of Science ®Google Scholar
• American Academy of Pain Medicine (APM) & American Pain Society (APS). The use of opioids for the treatment of chronic pain. A consensus statement from the American Academy of Pain Medicine and the American Pain Society. Clin J Pain 1997;13:6-8
   Google Scholar
• Mao J. Opioid-induced abnormal pain sensitivity: implications in clinical opioid therapy. Pain 2002;100:213-17
   PubMed Web of Science ®Google Scholar
• Cannon JG. Inflammatory Cytokines in Nonpathological States. News Physiol Sci 2000;15:298-303
   PubMedGoogle Scholar
• Walter MR. Structural biology of cytokines, their receptors, and signaling complexes: implications for the immune and neuroendocrine circuit. Chem Immunol 1997;69:76-98
   PubMed Web of Science ®Google Scholar
• Johnston IN, Milligan ED, Wieseler-Frank J, A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci 2004;24:7353-65
   PubMed Web of Science ®Google Scholar
• Peterson PK, Molitor TW, Chao CC. The opioid–cytokine connection. J Neuroimmunol 1998;83:63-9
   PubMed Web of Science ®Google Scholar
• Stefano GB. Autoimmunovascular regulation: morphine and anandamide and ancodamide stimulated nitric oxide release. J Neuroimmunol 1998;83:70-6
   PubMed Web of Science ®Google Scholar
• Takayama N, Ueda H. Morphine-induced chemotaxis and brain-derived neurotrophic factor expression in microglia. J Neurosci 2005;25:430-5
   PubMed Web of Science ®Google Scholar
• Hutchinson MR, Coats BD, Lewis SS, Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun 2008;22:1178-89
   PubMed Web of Science ®Google Scholar
• Raghavendra V, Rutkowski MD, DeLeo JA. The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. J Neurosci 2002;22:9980-9
   PubMed Web of Science ®Google Scholar
• Raghavendra V, Tanga FY, DeLeo JA. Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats. Neuropsychopharmacology 2004;29:327-34
   PubMed Web of Science ®Google Scholar
• Hutchinson MR, Lewis SS, Coats BD, Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain Behav Immun 2009;23:240-50
   PubMed Web of Science ®Google Scholar
• Ledeboer A, Hutchinson MR, Watkins LR, Johnson KW. Ibudilast (AV-411): a new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs 2007;16:935-50
   PubMed Web of Science ®Google Scholar
• Ledeboer A, Sloane EM, Milligan ED, Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. Pain 2005;115:71-83
   PubMed Web of Science ®Google Scholar
• Mika J, Osikowicz M, Makuch W, Przewlocka B. Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain. Eur J Pharmacol 2007;560:142-9
   PubMed Web of Science ®Google Scholar
• Raghavendra V, Tanga F, Rutkowski MD, DeLeo JA. Anti-hyperalgesic and morphine-sparing actions of propentofylline following peripheral nerve injury in rats: mechanistic implications of spinal glia and proinflammatory cytokines. Pain 2003;104:655-64
   PubMed Web of Science ®Google Scholar
• Dorazil-Dudzik M, Mika J, Schafer MK, The effects of local pentoxifylline and propentofylline treatment on formalin-induced pain and tumor necrosis factor-alpha messenger RNA levels in the inflamed tissue of the rat paw. Anesth Analg 2004;98:1566-73
   PubMed Web of Science ®Google Scholar
• Tawfik VL, Nutile-McMenemy N, Lacroix-Fralish ML, Deleo JA. Efficacy of propentofylline, a glial modulating agent, on existing mechanical allodynia following peripheral nerve injury. Brain Behav Immun 2007;21:238-46
   PubMed Web of Science ®Google Scholar
• Sweitzer S, De Leo J. Propentofylline: glial modulation, neuroprotection, and alleviation of chronic pain. Methylxanthines, Handbook of Experimental Pharmacology 200. Springer-Verlag; Berlin: 2011
   Google Scholar
• Hutchinson MR, Zhang Y, Shridhar M, Evidence that opioids may have toll like receptor 4 and MD-2 effects. Brain Behav Immun 2010;24:83-95
   PubMed Web of Science ®Google Scholar
• Mika J. Modulation of microglia can attenuate neuropathic pain symptoms and enhance morphine effectiveness. Pharmacol Rep 2008;60:297-307
   PubMed Web of Science ®Google Scholar
• Shavit Y, Wolf G, Goshen I, Interleukin-1 antagonizes morphine analgesia and underlies morphine tolerance. Pain 2005;115:50-9
   PubMed Web of Science ®Google Scholar
• Liu W, Wang CH, Cui Y, Inhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microglia. Neurosci Lett 2006;410:174-7
   PubMed Web of Science ®Google Scholar
• Bland ST, Hutchinson MR, Maier SF, The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release. Brain Behav Immun 2009;23:492-7
   PubMed Web of Science ®Google Scholar
• Hutchinson MR, Bland ST, Johnson KW, Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence and reward. ScientificWorldJournal 2007;7:98-111
   PubMedGoogle Scholar
• Thomas DM, Dowgiert J, Geddes TJ, Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines. Neurosci Lett 2004;367:349-54
   PubMed Web of Science ®Google Scholar
• Armstrong V, Reichel CM, Doti JF, Repeated amphetamine treatment causes a persistent elevation of glial fibrillary acidic protein in the caudate-putamen. Eur J Pharmacol 2004;488:111-15
   PubMed Web of Science ®Google Scholar
• Hou YJ, Yu AC, Garcia JM, Astrogliosis in culture. IV. Effects of basic fibroblast growth factor. J Neurosci Res 1995;40:359-70
   PubMed Web of Science ®Google Scholar
• Flores C, Rodaros D, Stewart J. Long-lasting induction of astrocytic basic fibroblast growth factor by repeated injections of amphetamine: blockade by concurrent treatment with a glutamate antagonist. J Neurosci 1998;18:9547-55
   PubMed Web of Science ®Google Scholar
• Flores C, Samaha AN, Stewart J. Requirement of endogenous basic fibroblast growth factor for sensitization to amphetamine. J Neurosci 2000;20:RC55
   PubMedGoogle Scholar
• Fantegrossi WE, Ciullo JR, Wakabayashi KT, A comparison of the physiological, behavioral, neurochemical and microglial effects of methamphetamine and 3,4-methylenedioxymethamphetamine in the mouse. Neurosci 2008;151:533-43
   PubMed Web of Science ®Google Scholar
• Pubill D, Canudas AM, Pallas M, Different glial response to methamphetamine- and methylenedioxymethamphetamine-induced neurotoxicity. Naunyn Schmiedebergs Arch Pharmacol 2003;367:490-9
   PubMed Web of Science ®Google Scholar
• Thomas DM, Walker PD, Benjamins JA, Methamphetamine neurotoxicity in dopamine nerve endings of the striatum is associated with microglial activation. J Pharmacol Exp Ther 2004;311:1-7
   PubMed Web of Science ®Google Scholar
• Zhang L, Kitaichi K, Fujimoto Y, Protective effects of minocycline on behavioral changes and neurotoxicity in mice after administration of methamphetamine. Prog Neuropsychopharmacol Biol Psychiatry 2006;30:1381-93
   PubMed Web of Science ®Google Scholar
• Park CH, Carboni E, Wood PL, Gee KW. Characterization of peripheral benzodiazepine type sites in a cultured murine BV-2 microglial cell line. Glia 1996;16:65-70
   PubMed Web of Science ®Google Scholar
• Kato H, Kogure K, Liu XH, Immunohistochemical localization of the low molecular weight stress protein HSP27 following focal cerebral ischemia in the rat. Brain Res 1995;679:1-7
   PubMed Web of Science ®Google Scholar
• Sekine Y, Ouchi Y, Sugihara G, Methamphetamine causes microglial activation in the brains of human abusers. J Neurosci 2008;28:5756-61
   PubMed Web of Science ®Google Scholar
• Banati RB. Visualising microglial activation in vivo. Glia 2002;40:206-17
   PubMed Web of Science ®Google Scholar
• Hashimoto K, Tsukada H, Nishiyama S, Protective effects of minocycline on the reduction of dopamine transporters in the striatum after administration of methamphetamine: a positron emission tomography study in conscious monkeys. Biol Psychiatry 2007;61:577-81
   PubMed Web of Science ®Google Scholar
• Mizoguchi H, Yamada K, Nabeshima T. Neuropsychotoxicity of abused drugs: involvement of matrix metalloproteinase-2 and -9 and tissue inhibitor of matrix metalloproteinase-2 in methamphetamine-induced behavioral sensitization and reward in rodents. J Pharmacol Sci 2008;106:9-14
   PubMed Web of Science ®Google Scholar
• Beardsley PM, Shelton KL, Hendrick E, Johnson KW. The glial cell modulator and phosphodiesterase inhibitor, AV411 (ibudilast), attenuates prime- and stress-induced methamphetamine relapse. Eur J Pharmacol 2010;637:102-8
   PubMed Web of Science ®Google Scholar
• Sofuoglu M, Mooney M, Kosten T, Minocycline attenuates subjective rewarding effects of dextroamphetamine in humans. Psychopharmacology (Berl) 2011;213:61-8
   PubMed Web of Science ®Google Scholar
• Fattore L, Puddu MC, Picciau S, Astroglial in vivo response to cocaine in mouse dentate gyrus: a quantitative and qualitative analysis by confocal microscopy. Neurosci 2002;110:1-6
   PubMed Web of Science ®Google Scholar
• Bowers MS, Kalivas PW. Forebrain astroglial plasticity is induced following withdrawal from repeated cocaine administration. Eur J Neurosci 2003;17:1273-8
   PubMed Web of Science ®Google Scholar
• Chen H, Uz T, Manev H. Minocycline affects cocaine sensitization in mice. Neurosci Lett 2009;452:258-61
   PubMed Web of Science ®Google Scholar
• Ciraulo DA, Sarid-Segal O, Knapp CM, Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence. Addiction 2005;100(Suppl 1):12-22
   PubMed Web of Science ®Google Scholar
• Grant BF, Stinson FS, Dawson DA, Co-occurrence of 12-month alcohol and drug use disorders and personality disorders in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 2004;61:361-8
   PubMed Web of Science ®Google Scholar
• Crews FT, Nixon K. Mechanisms of neurodegeneration and regeneration in alcoholism. Alcohol 2009;44:115-27
   Web of Science ®Google Scholar
• Obernier JA, White AM, Swartzwelder HS, Crews FT. Cognitive deficits and CNS damage after a 4-day binge ethanol exposure in rats. Pharmacol Biochem Behav 2002;72:521-32
   PubMed Web of Science ®Google Scholar
• Ward RJ, Colivicchi MA, Allen R, Neuro-inflammation induced in the hippocampus of 'binge drinking' rats may be mediated by elevated extracellular glutamate content. J Neurochem 2009;111:1119-28
   PubMed Web of Science ®Google Scholar
• He J, Crews FT. Increased MCP-1 and microglia in various regions of the human alcoholic brain. Exp Neurol 2008;210:349-58
   PubMed Web of Science ®Google Scholar
• Agrawal RG, Hewetson A, George CM, Minocycline reduces ethanol drinking. Brain Behav Immun 2011;25:S165-9
   PubMed Web of Science ®Google Scholar
• Stopponi S, Somaini L, Cippitelli A, Activation of the nuclear PPAR receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking. Biol Psychiatry 2011;69:642-9
   PubMed Web of Science ®Google Scholar
• Hutchinson MR, Shavit Y, Grace PM, Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia. Pharmacol Rev 2011;63:772-810
   PubMed Web of Science ®Google Scholar
• Frank MG, Watkins LR, Maier SF. Stress- and glucocorticoid-induced priming of neuroinflammatory responses: potential mechanisms of stress-induced vulnerability of drugs of abuse. Brain Behav Immun 2011;25:S21-8
   PubMed Web of Science ®Google Scholar