1,822
Views
21
CrossRef citations to date
0
Altmetric
Editorial

Angiotensin II type 2 receptor agonists – where should they be applied?

, MD PhD & , MD PhD
Pages 763-766 | Published online: 21 Apr 2012

Bibliography

  • Verdonk K, Danser AHJ, van Esch JHM. Angiotensin II type 2 receptor agonists: where should they be applied? Expert Opin Investig Drugs 2012;21:501-13
  • Wan Y, Wallinder C, Plouffe B, Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. J Med Chem 2004;47:5995-6008
  • Habashi JP, Doyle JJ, Holm TM, Angiotensin II type 2 receptor signaling attenuates aortic aneurysm in mice through ERK antagonism. Science 2011;332:361-5
  • Matavelli LC, Huang J, Siragy HM. Angiotensin AT2 receptor stimulation inhibits early renal inflammation in renovascular hypertension. Hypertension 2011;57:308-13
  • Gelosa P, Pignieri A, Fandriks L, Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage. J Hypertens 2009;27:2444-51
  • Paulis L, Becker STR, Lucht K, Direct angiotensin II type 2 receptor stimulation in Nomega-Nitro-L-Arginine-Methyl Ester-induced hypertension: the effect on pulse wave velocity and aortic remodelling. Hypertension 2012;59:485-92
  • Rehman A, Leibowitz A, Yamamoto N, Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension 2012;59:291-9
  • Jing F, Mogi M, Sakata A, Direct stimulation of angiotensin II type 2 receptor enhances spatial memory. J Cereb Blood Flow Metab 2012;32:248-55
  • McCarthy CA, Vinh A, Callaway JK, Widdop RE. Angiotensin AT2 receptor stimulation causes neuroprotection in a conscious rat model of stroke. Stroke 2009;40:1482-9
  • Rompe F, Artuc M, Hallberg A, Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. Hypertension 2010;55(4):924-31
  • Wu L, Iwai M, Li Z, Regulation of inhibitory protein-kappaB and monocyte chemoattractant protein-1 by angiotensin II type 2 receptor-activated Src homology protein tyrosine phosphatase-1 in fetal vascular smooth muscle cells. Mol Endocrinol 2004;18(3):666-78
  • Steckelings UM, Widdop RE, Paulis L, Unger T. The angiotensin AT2 receptor in left ventricular hypertrophy. J. Hypertens 2010;28(Suppl 1):S50-5
  • Bosnyak S, Welungoda IK, Hallberg A, Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats. Br J Pharmacol 2010;159(3):709-16
  • Hilliard LM, Jones ES, Steckelings UM, Sex-specific influence of Angiotensin type 2 receptor stimulation on renal function: a novel therapeutic target for hypertension. Hypertension 2012;59(2):409-14
  • Kaschina E, Grzesiak A, Li J, Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction? Circulation 2008;118(24):2523-32
  • Gao J, Zhang H, Le KD, Activation of central angiotensin type 2 receptors suppresses norepinephrine excretion and blood pressure in conscious rats. Am J Hypertens 2011;24(6):724-30

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.