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Drug Evaluation

Docetaxel for the treatment of bladder cancer

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Bibliography

  • • of interest
  • •• of considerable interest
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• This is a randomized phase II trial that did not demonstrate improved outcomes by the combination of vendetanib with docetaxel,and revealed a dismal median PFS of 1.58 months and median OS of 7.03 months with docetaxel.

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• This is a recently reported randomized phase II trial that revealed a significant extension of PFS with the combination of ramucirumab with docetaxel as salvage therapy for metastatic UC.

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