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Editorial

Investigational new drugs for focal epilepsy

Bibliography

  • Papers of special note have been highlighted as either of interest (●) or of considerable interest (●●) to readers.
  • Banerjee PN, Filippi D, Hauser WA. The descriptive epidemiology of epilepsy-A review. Epilepsy Res. 2009;85(1):31–45.
  • Mula M, Cock HR. More than seizures: improving the lives of people with refractory epilepsy. Eur J Neurol. 2015;22(1):24–30.
  • Friedman D, Devinsky O. Canniboids in the treatment of epilepsy. New Engl J Med. 2015;373:1048–1058.
  • Bialer M, Johannessen SI, Levy RH, et al. Progress report on new antiepileptic drugs: a summary of the Twelfth Eilat Conference (EILAT XII). Epilepsy Res. 2015;111:85–141.

●● Comprehensive overview of preclinical and clinical studies on investigational drugs for epilepsy.

● Overview of drugs under development for focal epilepsy.

  • Porta N, Vallée L, Lecointe C, et al. Fenofibrate, a peroxisome proliferator-activated receptor-alpha agonist, exerts anticonvulsive properties. Epilepsia. 2009;50(4):943–948.
  • Klein P, Tyrlikova I, Mathews GC. Dietary treatment in adults with refractory epilepsy: a review. Neurology. 2014;83(21):1978–1985.
  • Curatolo P, Moavero R. mTOR inhibitors as a new therapeutic option for epilepsy. Expert Rev Neurother. 2013;13:627–638.
  • Abraham J, Fox PD, Condello C, et al. Minocycline attenuates microglia activation and blocks the long-term epileptogenic effects of early-life seizures. Neurobiol Dis. 2012;46:425–430.
  • Wykes RC, Kullmann DM, Pavlov I, et al. Optogenetic approaches to treat epilepsy. J Neurosci Methods. 2015. DOI:10.1016/j.jneumeth.2015.06.004. [Epub ahead of print].

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