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Targeting angiogenesis in endometrial cancer - new agents for tailored treatments

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●● This article is very important because it describes very well the natural history and the state-of-the-art treatment of endometrial cancer.

●● This article is most important because it represents the new paradigm of microenvironment target therapy.

●● This article is very fascinating because it underlines the determinant role of the tumor niche and its importance as therapeutical target.

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● A high-impact paper focusing on the role of VEGF and its receptors regarding angiogenesis.

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●● This article is important for its contribution to the knowledge of a possible hormonal target in the treatment of endometrial cancer.

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● A study confirming clinical benefit of BV in association with chemotherapy for advanced endometrial cancer.

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● A high-impact report showing activity of aflibercept in advanced endometrial cancer.

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