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Research

Endothelin as a target for drug development: Recent progress

Pages 179-180 | Published online: 03 Mar 2008

References

  • YANAGISAWA M, KURIHARA H, KIMURA S, TOMOBE Y, KOBAYASHI M, MITSUI Y, YAZAKI Y, GOTO K, MASAKI T: A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (1988) 332:411–415.
  • CLOZEL M, BREU V, BURRI K, CASSAL J-M, FISCHLI W, GRAY GA, HIRTH G, LOFFLER B-M, MULLER M, NEIDHART W, RAMUZ H: Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist Nature (1993) 365:759–761.
  • CLOZEL M, CLOZEL JP, HESS P: Endothelin receptor antagonism - A new therapeutic approach in experi-mental hypertension. Circulation (1993) 88:316.
  • MUGRAGE B, MOLITERNI J, ROBINSON L, WEBB RL, SHETTY SS, LIPSON KE, CHIN MH, NEALE R, CIOFFI C: CGS tagonist Bioorganic & Med. Chem. Letters (1993) 3:2099–2104.
  • SCHOEFFTER P, RANDRIANTSOA A: Differences between endothelin receptors mediating contraction of guinea pig aorta and pig coronary artery. Eur. I Pharrnacol. (1993) 249:199–206.
  • WARNER TD, ALLCOCK GH, MICKLEY EJ, VANE JR: Char-acterization of endothelin receptors mediating the ef-fects of the endothelin/sarafotoxin peptides on autonomic neurotransmission in the rat vas deferens and guinea pig ileum. Br. j Pharmacol. (1993) 110:783–789.
  • SUDJARWO SA, HORI M, TAKAI M, URADE Y, OKADA T,KARAKI H: A novel subtype of endothelin B receptor mediating contraction in swine pulmonary vein. Life Sci (1993) 53:431–437.
  • WARNER TD, ALLCOCK GH, CORDER R, VANE JR: Use ofthe endothelin antagonists BQ-123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and release of EDRF. Br. J. Pharma-col. (1993) 110:777–782.
  • BAX WA, BOS E, SAXENA PR: Heterogeneity of en-dothelin/sarafotoxin receptors mediating contraction of the human isolated saphenous vein. Eur.J. Pharmacol. (1993) 239:267–268.
  • LOFFLER B-M, BREU V, CLOZEL M: Effect of different endothelin receptor antagonists and of the novel non-peptide antagonist Ro 46–2005 on endothelin levels in rat plasma. FESS 1314 7 (1993) 333:108–110.
  • DOHERTY AM: Endothelin: A new challenge. J. Med. Chem. (1992) 35:1493–1508.
  • Peter KS Siegl, Merck Research Laboratories, West Point, PA 19486,

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