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Review

Dual β-lactam-fluoroquinolone compounds: a novel approach to antibacterial treatment

Pages 1479-1499 | Published online: 23 Feb 2005

Bibliography

  • O'CALLAGHAN C, SYKES RB, STANFORTH SE: A new cephalosporin with a dual mode of action. Antimicrob. Agent Chemother. (1976) 10:245–248.
  • GREENWOOD D, O'GRADY F: Dual action cephalosporin utilising a novel therapeutic principle. Antimicrob. Agents Chemother. (1976) 10:249–252.
  • MOBASHERY S, LERNER S.A, JOHNSTON M: Conscripting Plactamase for use in drug delivery. Synthesis and biological activity of a cephalosporin Cio-ester of an antibiotic dipeptide. J. Am. Chem. Soc. (1986) 108:1685–1686.
  • HAMILTON-MILLER JMT, NEWTON GGF, ABRAHAM EP: Products of aminolysis and enzymic hydrolysis of the cephalosporins. Biochem. J. (1970) 116:371–384.
  • O'CALLAGHAN CH, KIRBY SM, MORRIS A, WALLER RE, DUNCOMBE RE: Correlation between hydrolysis of the beta-lactam bond of the cephalosporin nucleus and expulsion of the 3-substituent. J. Bacteriol. (1972) 110:988–991.
  • WICK WE, PRESTON DA: Biological properties of three 3-heterocyclic cephalosporin antibiotics. Antimicrob. Agents Chemother. (1972) 1:221–234.
  • GEORGOPAPAKAKOU NH, BERTASSO A: Mechanisms of action of cephalosporin 3'-quinolone esters, car-bamates, and tertiary amines in Escherichia coil. An-timicrob. Agent Chemother. (1993) 37:559–565.
  • GEORGOPAPADAKOU N, MCCAFFREY C: I3-lactamase hy-drolysis of cephalosporin 3' quinolone esters, car-ba mate, and tertiary amines. Antimicrob. Agent Chemother. (1994) 38:859–962.
  • GEORGOPAPADAKOU N, BERTASSO A, CHAN KK et al.:Mode of action of the dual-action cephalosporin Ro 23-9424. Antimicrob. Agent Chemother. (1989) 33:1067–1071.
  • PACE J, BERTASSO A, GEORGAPAPADAKOU N: Es-cherichia coli resistant to cephalosporins and qui-nolones is still susceptible to the cephalosporin-quinolone ester Ro 23-9424. Antimicrob. Agent Chemother. (1991) 35:910–915.
  • CHAPMAN JS, BERTASTO A, CUMMINGS LM, GEORGEPA-PADAKOU NH: Low-level resistance to cephalosporin 3'-quinolone ester Ro 23-9424 in Escherichia coil. An-timicrob. Agents Chemother. (1995) 39:564–566.
  • NICKERSON B, CUNNINGHAM B, SCYPINSKI S: The use of capillary electrophoresis to monitor the stability of a dual-action cephalosporin in solution.' Pharm. Biomed. Analy. (1995) 14:73–83.
  • ALBRECHT HA, BESKID G, CHAN KK et al: Cephalosporin 3'-quinolone esters with a dual mode of action. J. Med. Chem. (1990) 33:77–86.
  • DEMUTH TP, Jr., WHITE RE, TIETJEN RA et al.: Synthesis and antibacterial activity of new C-10 quinolonyl-cephem esters. J. Antibiotic (1991) 44:200–209.
  • JONES RN, BARRY A.L, THORNSBERRY C: Antimicrobial activity of Ro 23-9424, a novel ester-linked co-drug of fleroxacin and desacetylcefotaxime. Antimicrob. Agent Chemother. (1989) 33:944–950.
  • JONES RN, BARRY AL: In vitro activity of Ro 23-9424, ceftazidime, and eight other newer beta-lactams against 100 Gram-positive blood culture isolates. Diagn. Micro-bic)]. Infect. Dis. (1989) 12:143–147.
  • ROLSTON KVI, NGUYEN H.T, HO DH, LE BLANC B, BODEYGP: In vitro activity of Ro 23-9424, a dual-action antibac-terial agents against bacterial isolates from cancer pa-tients compared with those of other agents. Antimicrob. Agent Chemother.(1992) 36:879–882 .
  • BESKID G, FALLAT V, LIPSCHITZ ER et al: In vitroactivitiesof a dual-action antibacterial agent, Ro 23-9424 and comparative agents. Antimicrob. Agent Chemother. (1989) 33:1072–1077.
  • GU JN, NEU HC: In vitro activity of Ro 23-9424, adual-action cephalosporin, compared with activities of other antibiotics. Antimicrob. Agent Chemother.(1990) 34:189–195.
  • SPANGLER SK, JACOBS MR, PANKUCH GA, APPELBAUMPA: Susceptibility of 170 penicillin-susceptible and penicillin-resistant pneumococci to six oral cepha-losporins, four quinolones, desacetylcefotaxime, Ro 23-9424 and RP 67829. J. Antimicrob. Chemother. (1993) 31:273–280.
  • QUADRI SMH, UENO Y, SALDIN H, CUNHA BA: In vitroactivity of Ro 23-9424, a dual-acting cephalosporin -quinolone antimicrobial agent. J. Clin. Pharmacol (1993) 33:923–928.
  • ALDRIDGE KE, JONES RN, BARRY AL, GELFAND MS: Invitro activity of various antimicrobial agents against S. aureus isolates including fluoroquinolones- and oxac-illin-resistant strains. Diagn. Nlicrobiol. Infect. Dis (1992) 15:517–521.
  • QUADRI SMH, UENO Y, AYUB A: Anti Brucella activity ofRo 23-9424, a dual action antibacterial. Chemotherapy (1993) 39:386–389.
  • EDELSTEIN P, EDELSTEIN MAC: In vitro activity of Ro 23-9424 against clinical isolates of Legionella species. Antimicrob. Agent Chemother. (1992) 36:2559–2561
  • PFALLER MA, BARRY AL, FUCHS PC: Ro 23-9424, a new cephalosporin 3'-quinolone: in vitro antimicrobial ac-tivity and tentative disk diffusion interpretative criteria. Antimicrob. Chemother. (1993) 31:81–88.
  • BESKID G, SIEBELIS J, MC GARRY CM et al.: In vivoevaluation of a dual-action antibacterial, Ro 23–9424, compared to cefotaxime and fleroxacin. Chemotherapy (1990) 36:106–109.
  • CHRISTENSON JG, CHAN KK, CLEELAND R et al.: Pharma-cokinetics of Ro 23-9424, a dual-action cephalosporin in animals. Antimicrob. Agent Chemother.(1990) 34:1895–1900.
  • MOULD D, PATEL I, GINSBERGR et al.: The pharrnacokinetics of Ro 23–9424, a novel antimicrobial agent. Pharm. Res. (1991) 8 (Suppl. PPDM 8326R):S–307.
  • ALBRECHT HA, BESKID G, CHRISTENSON JG: Dual-action cephalosporins: cephalosporin 3'-quaternary ammo-nium quinolones. J. Med. Chem. (1991) 34:669–675.
  • JONES RN: In vitro activity of Ro 24-6392, a novel ester-linked co-drug combining ciprofloxacin and de-sacetylcefotaxime. Eur.J. Gin. Microbic)]. Infect. Dis. (1990) 9:435–438.
  • VANDER ROEST S, GOGLIOTTI R, SANCHEZ J, SAUNDERSJ: Synthesis and antimicrobial activity of new dual-ac-tion cephalosporin potential oral agents. 35th Intersci. Conf. Antimicrob. Agent Chemother. San Francisco (1995) F–25.
  • SANCHEZ J, GOGLIOTTI R, DAX S et al.: Synthesis andantimicrobial activity of a series of dual action cepha-losporins as potential oral agents. 35th Intersci. Conf. Antimicrob. Agents Chemother. San Francisco (1995).
  • SAUNDERS J, BRADFORD L, GUTTENDORF R et al.: Oralbioavailability of a series of new dual action cepha-losporins. 35th Intersci. Con! Antimicrob. Agents Chemother. San Francisco (1995) F–26.
  • GRAY JL, SHRUM GP, GASPARSKI CM et al.: Antibacterial activity of multifunctional quinolonyl-cephem 2'-amines. 35th Intersci. Con! Antimicrob. Agents Chemother. San Francisco (1995) F–27.
  • WHITE RE, DEMUTH TP, Jr., BERK JD et al.: Preparation and comparative antibacterial activity of quinolonyl-cephem amines and carbamates. 33rd Intersci. Conf. Antimicrob. Agent Chemother. New Orleans (1993). Abstract 1491:392.
  • LEUNK HD, MCKEEVER CA, DEVRIES JL et al.: In vitroactivity of quinolonyl-cephem amine. 37th Intersci. Conf. Antimicrob. Agent Chemother. Toronto (1997):179. Abstract F–195.
  • WHITE RE, GASPARSKI CM, KIM NK et al.: Synthesis and bioloogical evaluation of quinolonyl-carbacepha-losporin antibacterial. 37th Intersci. Con! Antimicrob. Agent Chemother. Toronto (1997):179. Abstract F–193.
  • ALBRECHT HA, BESKID G, CHRISTENSON JC et al.: Dual-action cephalosporins incorporating a 3'-tertiary-amine linked quinolone. J. Med. Chem. (1994) 37:400–407.
  • JONES RN, SANCHÉZ ML: Antimicrobial activity of a new antipseudomonal dual-action drug Ro 25-0534. Diagn. Nlicrobiol. Infect Dis (1994) 18:61–68.
  • MAX, DAVIS BW, O'HARA TL et al: Synthesis and multi-functional antibacterial activity of new quinolonyl-cephem 3-amines. 34th Intersci. Con! Antimicrob. Agent Chemother. Orlando (1994). Abstract F-159:204.
  • DEMUTH TP, Jr., WHITE RE, TIETJEN RA et al.: Synthesis and antimicrobial activity of new, high potency C-10 quinolonyl-cephem dithiocarbamates. 33rd Intersci. Con! Antimicrob. Agent Chemother. New Orleans (1993) Abstract 1490:392.
  • KRAFT WG, ROWKE FS, DEMUTH TP, Jr. et al: In vitro activity of quinolonyl-cephem dithiocarbamates. 36th Intersci. Con! Antimicrob. Agent Chemother. New Orleans (1996):F–165.
  • JOHNSON D, ERWIN M, JONES RN: Antimicrobial activity and spectrum of novel cephalosporin-fluoroquinolone dual action compounds (DAC), CQEPCTM-397 and CQEPCTM-414. 36th Intersci. Conf Antimicrob. Agent Chemother. New Orleans (1996). Abstract no.
  • PERRONE E, ZARINI F, VISENTI G et al: Dual-action penems. 31st Intersci. Conf. Antimicrob. Agent Chemother. Chicago (1990:236. Abstract 825.
  • CORRAZ AJ, DAX SL, DUNLAP NK et al.: Dual-action penems and carbapenems. J. Med. Chem. (1992) 35:1828–1839 .
  • PERRONE E, JABES D, ALPEGIANI M et al.: Dual-action penems. J. Antibiotic (1992) 45:589–594.
  • ROURKE FJ, DAVIS BW, KRAFT WC et al.: In vitro activity of two new quinolonyl-penem carbamates. 33rd Intersci. Con! Antimicrob. Agent Chemother. New Orleans (1993). Abstract 1489:391.
  • HU XE, MORGAN JD, HERSHBERGER PM et al.: Multifunc-tional quinolonyl-penem carbamates and their antibac-terial activities. 36th Intersci. Con! Antimicrob. Agent Chemother. New Orleans (1996):F–168.
  • WALLING MA, WHITE RE, SWIFT RA et al.: Pharmacoki-netics and in vivo efficacy of quinolyl-lactam antibacte-rials. 36th Intersci. Con! Antimicrob. Agent Chemother. New Orleans (1996) F–169.
  • CRAIG W, ANDES D, WALKER R, URBAN A, EBERT S: Pharmacodynamic activities of a quinolonyl-penem carbamate (QD) in an animal infection model. 34th Intersci. Conf. Antimicrob. Agent Chemother. Orlando (1994). Abstract F-157:204.
  • HERSHBERGER PM, SWITZER AG, YELM KE et al.: Synthe-sis and biological evaluation of 2-thio ether-linked quinolonyl-carbapenems. 36th Intersci. Con! Antimicrob. Agent Chemother. New Orleans (1996):F–170.
  • ALEX RR, KULKARNI VM: Design and synthesis of p enicil-loyloxymethyl quinolone carbamates as a new class of dual-activity antibacterials. Eur. J. Med. Chem. (1995) 30:815–818.

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