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Expert Opinion on Pharmacotherapy Volume 12, 2011 - Issue 1
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Clinical Trial Evaluations

Defining the optimal dose of aspirin and clopidogrel in acute coronary syndromes

Evaluation of ‘Dose comparisons of clopidogrel and aspirin in acute coronary syndromes’, N Engl J Med 2010;363:930-42

Hitinder S Gurm University of Michigan Health System, Division of Cardiovascular Medicine, University of Michigan Cardiovascular Center, 2A394, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5853, USA +1 734 232 4276; +1 734 764 4142; [email protected]
, MD &
Kim A Eagle University of Michigan Health System, Division of Cardiovascular Medicine, University of Michigan Cardiovascular Center, 2A394, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5853, USA +1 734 232 4276; +1 734 764 4142; [email protected]
, MD
Pages 149-151 | Published online: 26 Nov 2010

Bibliography

  • Gurm HS, Bhatt DL. Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors. Am Heart J 2005;149(1 Suppl):S43-53
  • Topol EJ. Toward a new frontier in myocardial reperfusion therapy: emerging platelet preeminence. Circulation 1998;97:211-18
  • Collins JS, Gurm HS. The role of clopidogrel in revascularized and nonrevascularized patients with acute coronary syndromes. Am J Cardiovasc Drugs 2007;7:159-68
  • Bhatt DL. Intensifying platelet inhibition – navigating between Scylla and Charybdis. N Engl J Med 2007;357:2078-81
  • Mehta SR, Bassand JP, Chrolavicius S, Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. N Engl J Med 2010;363:930-42
  • Mehta SR, Tanguay JF, Eikelboom JW, Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial. Lancet 2010;376:1233-43
  • Campbell CL, Smyth S, Montalescot G, Steinhubl SR. Aspirin dose for the prevention of cardiovascular disease: a systematic review. JAMA 2007;297:2018-24
  • Montalescot G, Wiviott SD, Braunwald E, Prasugrel compared with clopidogrel in patients undergoing percutaneous coronary intervention for ST-elevation myocardial infarction (TRITON-TIMI 38): double-blind, randomised controlled trial. Lancet 2009;373:723-31
  • Wiviott SD, Braunwald E, McCabe CH, Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2007;357:2001-15
  • Wiviott SD, Trenk D, Frelinger AL, Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation 2007;116:2923-32
  • Wallentin L, Becker RC, Budaj A, Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009;361:1045-57
  • Cannon CP, Harrington RA, James S, Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study. Lancet 2010;375:283-93

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