Intermittent preventive treatment of malaria in pregnant women and infants: making best use of the available evidence

Bibliography

• Greenwood B. The use of anti-malarial drugs to prevent malaria in the population of malaria-endemic areas. Am J Trop Med Hyg 2004;70(1):1-7
   PubMed Web of Science ®Google Scholar
• Geerligs PD, Brabin BJ, Eggelte TA. Analysis of the effects of malaria chemoprophylaxis in children on haematological responses, morbidity and mortality. Bull World Health Organ 2003;81(3):205-16
   PubMed Web of Science ®Google Scholar
• UNICEF. The state of the world's children 2008. UNICEF; New York: 2007
   Google Scholar
• WHO. World Health Organization. The World malaria Report 2009. Available from: http://wwwwhoint/malaria/world_malaria_report_2009/en/indexhtml
   Google Scholar
• van Eijk AM, Hill J, Alegana VA, Coverage of malaria protection in pregnant women in sub-Saharan Africa: a synthesis and analysis of national survey data. Lancet Infect Dis 2011;11(3):190-207
   PubMed Web of Science ®Google Scholar
• WHO. WHO Policy recommendation on Intermittent Preventive Treatment during infancy with sulphadoxine-pyrimethamine (SP-IPTi) for Plasmodium falciparum malaria control in Africa,March 2010. Available from: http://www.who.int/malaria/news/WHO_policy_recommendation_IPTi_032010.pdf 2010
   Google Scholar
• WHO. Policy Recommendation: Seasonal Malaria Chemoprevention (SMC) for Plasmodium falciparum malaria control in highly seasonal transmission areas of the Sahel subregion in Africa, March 2012. Available from: http://www.who.int/malaria/publications/atoz/who_smc_policy_recommendation/en/index.html
   Google Scholar
• White NJ. Intermittent presumptive treatment for malaria. PLoS Med 2005;2(1):e3
   PubMed Web of Science ®Google Scholar
• Greenwood B. Intermittent preventive antimalarial treatment in infants. Clin Infect Dis 2007;45(1):26-8
   PubMed Web of Science ®Google Scholar
• Cairns M, Carneiro I, Milligan P, Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana. PLoS ONE 2008;3(5):e2227
   Web of Science ®Google Scholar
• May J, Adjei S, Busch W, Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon. Malar J 2008;7:198
   PubMed Web of Science ®Google Scholar
• WHO. Policy recommendation on Intermittent Preventive Treatment during infancy with sulphadoxine-pyrimethamine (SP-IPTi) for Plasmodium falciparum malaria control in Africa, March 2010. Available from: http://www.who.int/malaria/news/WHO_policy_recommendation_IPTi_032010.pdf.2010
   Google Scholar
• Chandramohan D, Owusu-Agyei S, Carneiro I, Cluster randomised trial of intermittent preventive treatment for malaria in infants in area of high, seasonal transmission in Ghana. BMJ 2005;331(7519):727-33
   PubMedGoogle Scholar
• Macete E, Aide P, Aponte JJ, Intermittent preventive treatment for malaria control administered at the time of routine vaccinations in Mozambican infants: a randomized, placebo-controlled trial. J Infect Dis 2006;194(3):276-85
   PubMed Web of Science ®Google Scholar
• Kobbe R, Kreuzberg C, Adjei S, A randomized controlled trial of extended intermittent preventive antimalarial treatment in infants. Clin Infect Dis 2007;45(1):16-25
   PubMed Web of Science ®Google Scholar
• Grobusch MP, Lell B, Schwarz NG, Intermittent preventive treatment against malaria in infants in Gabon–a randomized, double-blind, placebo-controlled trial. J Infect Dis 2007;196(11):1595-602
   PubMed Web of Science ®Google Scholar
• Mockenhaupt FP, Reither K, Zanger P, Intermittent preventive treatment in infants as a means of malaria control: a randomized, double-blind, placebo-controlled trial in northern Ghana. Antimicrob Agents Chemother 2007;51(9):3273-81
   PubMed Web of Science ®Google Scholar
• Aponte JJ, Schellenberg D, Egan A, Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six randomised, placebo-controlled trials. Lancet 2009;374(9700):1533-42
   PubMed Web of Science ®Google Scholar
• Schellenberg D, Menendez C, Aponte JJ, Intermittent preventive antimalarial treatment for Tanzanian infants: follow-up to age 2 years of a randomised, placebo-controlled trial. Lancet 2005;365(9469):1481-3
   PubMed Web of Science ®Google Scholar
• Sutherland CJ, Drakeley CJ, Schellenberg D. How is childhood development of immunity to plasmodium falciparum enhanced by certain antimalarial interventions? Malar J 2007;6:161
   PubMed Web of Science ®Google Scholar
• Schellenberg D, Menendez C, Kahigwa E, Intermittent treatment for malaria and anaemia control at time of routine vaccinations in Tanzanian infants: a randomised, placebo-controlled trial. Lancet 2001;357(9267):1471-7
   PubMed Web of Science ®Google Scholar
• Menendez C, Schellenberg D, Macete E, Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications. Malar J 2007;6:132
   PubMed Web of Science ®Google Scholar
• Odhiambo FO, Hamel MJ, Williamson J, Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial. PLoS One 2010;5(4):e10016
   Google Scholar
• Menendez C, D'Alessandro U, ter Kuile FO. Reducing the burden of malaria in pregnancy by preventive strategies. Lancet Infect Dis 2007;7(2):126-35
   PubMed Web of Science ®Google Scholar
• Desai M, ter Kuile FO, Nosten F, Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 2007;7(2):93-104
   PubMed Web of Science ®Google Scholar
• Menendez C, Bardaji A, Sigauque B, A randomized placebo-controlled trial of intermittent preventive treatment in pregnant women in the context of insecticide treated nets delivered through the antenatal clinic. PLoS One 2008;3(4):e1934
   PubMed Web of Science ®Google Scholar
• Mbaye A, Richardson K, Balajo B, A randomized, placebo-controlled trial of intermittent preventive treatment with sulphadoxine-pyrimethamine in Gambian multigravidae. Trop Med Int Health 2006;11(7):992-1002
   PubMed Web of Science ®Google Scholar
• Njagi JK, Magnussen P, Estambale B, Prevention of anaemia in pregnancy using insecticide-treated bednets and sulfadoxine-pyrimethamine in a highly malarious area of Kenya: a randomized controlled trial. Trans R Soc Trop Med Hyg 2003;97(3):277-82
   PubMed Web of Science ®Google Scholar
• Parise ME, Ayisi JG, Nahlen BL, Efficacy of sulfadoxine-pyrimethamine for prevention of placental malaria in an area of Kenya with a high prevalence of malaria and human immunodeficiency virus infection. Am J Trop Med Hyg 1998;59(5):813-22
   PubMed Web of Science ®Google Scholar
• Schultz LJ, Steketee RW, Macheso A, The efficacy of antimalarial regimens containing sulfadoxine-pyrimethamine and/or chloroquine in preventing peripheral and placental plasmodium falciparum infection among pregnant women in Malawi. Am J Trop Med Hyg 1994;51(5):515-22
   PubMed Web of Science ®Google Scholar
• Shulman CE, Dorman EK, Cutts F, Intermittent sulphadoxine-pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy: a randomised placebo-controlled trial. Lancet 1999;353(9153):632-6
   PubMed Web of Science ®Google Scholar
• WHO. WHO expert committee on malaria. World Health Organization; Geneva: 2000
   Google Scholar
• WHO. A strategic framework for malaria prevention and control during pregnancy in the African region. World Health Organization; Geneva: 2004; AFR/MAL
   Google Scholar
• Hamer DH, Mwanakasale V, Macleod WB, Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-seropositive pregnant Zambian women. J Infect Dis 2007;196(11):1585-94
   PubMed Web of Science ®Google Scholar
• Menendez C, Bardaji A, Sigauque B, Malaria prevention with IPTp during pregnancy reduces neonatal mortality. PLoS One 2010;5(2):e9438
   Web of Science ®Google Scholar
• Maiga OM, Kayentao K, Traore BT, Superiority of 3 over 2 doses of intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria during pregnancy in mali: a randomized controlled trial. Clin Infect Dis 53(3):215-23
   PubMed Web of Science ®Google Scholar
• Greenwood BM, Greenwood AM, Snow RW, The effects of malaria chemoprophylaxis given by traditional birth attendants on the course and outcome of pregnancy. Trans R Soc Trop Med Hyg 1989;83(5):589-94
   PubMed Web of Science ®Google Scholar
• Bardaji A, Sigauque B, Sanz S, Impact of malaria at the end of pregnancy on infant mortality and morbidity. J Infect Dis 2011;691-699
   Google Scholar
• Armstrong Schellenberg JR, Shirima K, Maokola W, Community effectiveness of intermittent preventive treatment for infants (IPTi) in rural southern Tanzania. Am J Trop Med Hyg 2010;82(5):772-81
   PubMed Web of Science ®Google Scholar
• Gosling RD, Gesase S, Mosha JF, Protective efficacy and safety of three antimalarial regimens for intermittent preventive treatment for malaria in infants: a randomised, double-blind, placebo-controlled trial. Lancet 2009;374(9700):1521-32
   PubMed Web of Science ®Google Scholar
• Schellenberg D, Cisse B, Menendez C. The IPTi consortium: research for policy and action. Trends Parasitol 2006;22(7):296-300
   PubMed Web of Science ®Google Scholar
• Gosling RD, Carneiro I, Chandramohan D. Intermittent preventive treatment of malaria in infants: how does it work and where will it work? Trop Med Int Health 2009;14(9):1003-10
   PubMed Web of Science ®Google Scholar
• Institute of Medicine: Committee on the perspectives of the role of intermittent preventive treatment for malaria in infants. Assessment of the role of intermittent preventive treatment for malaria in infants: Letter report. Available from: http://www.nap.edu/catalog/12180.htlm 2008
   Google Scholar
• Senn N, Rarau P, Stanisic DI, Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to plasmodium falciparum and P. vivax: a randomized controlled trial. PLoS Med 2012;9(3):e1001195
   Web of Science ®Google Scholar
• Massaga JJ, Kitua AY, Lemnge MM, Effect of intermittent treatment with amodiaquine on anaemia and malarial fevers in infants in Tanzania: a randomised placebo-controlled trial. Lancet 2003;361(9372):1853-60
   PubMed Web of Science ®Google Scholar
• Willey BA, Armstrong Schellenberg JR, Maokola W, Evaluating the effectiveness of IPTi on malaria using routine health information from sentinel health centres in southern Tanzania. Malar J 2011;10(1):41
   PubMedGoogle Scholar
• de Sousa A, Salama P, Chopra M. Implementing intermittent preventive treatment in infants. Lancet 2010; 375(9709):121
   PubMed Web of Science ®Google Scholar
• Mayor A, Serra-Casas E, Sanz S, Molecular markers of resistance to sulfadoxine-pyrimethamine during intermittent preventive treatment for malaria in Mozambican infants. J Infect Dis 2008;197(12):1737-42
   PubMed Web of Science ®Google Scholar
• Bjorkman A, Phillips-Howard PA. Adverse reactions to sulfa drugs: implications for malaria chemotherapy. Bull World Health Organ 1991;69(3):297-304
   PubMed Web of Science ®Google Scholar
• Briand V, Bottero J, Noel H, Intermittent treatment for the prevention of malaria during pregnancy in Benin: a randomized, open-label equivalence trial comparing sulfadoxine-pyrimethamine with mefloquine. J Infect Dis 2009;200(6):991-1001
   PubMed Web of Science ®Google Scholar
• Sevene E, Gonzalez R, Menendez C. Current knowledge and challenges of antimalarial drugs for treatment and prevention in pregnancy. Expert Opin Pharmacother 2010;11(8):1277-93
   PubMed Web of Science ®Google Scholar
• World Health Organization (WHO). A strategic framework for malaria prevention and control during pregnancy in the African region: report AFR/MAL/04/01. WHO Regional Office for Africa; Brazzaville, Democratic Republic of Congo: 2006
   Google Scholar
• Taylor WR, White NJ. Antimalarial drug toxicity: a review. Drug Saf 2004;27(1):25-61
   PubMed Web of Science ®Google Scholar
• Steffen R, Somaini B. Severe cutaneous adverse reactions to sulfadoxine-pyrimethamine in Switzerland. Lancet 1986;1(8481):610
   PubMed Web of Science ®Google Scholar
• Nyunt MM, Adam I, Kayentao K, Pharmacokinetics of sulfadoxine and pyrimethamine in intermittent preventive treatment of malaria in pregnancy. Clin Pharmacol Ther 2009;87(2):226-34
   PubMed Web of Science ®Google Scholar
• Luzzatto L. The rise and fall of the antimalarial Lapdap: a lesson in pharmacogenetics. Lancet 2010;376(9742):739-41
   PubMed Web of Science ®Google Scholar
• Menendez C, Kahigwa E, Hirt R, Randomised placebo-controlled trial of iron supplementation and malaria chemoprophylaxis for prevention of severe anaemia and malaria in Tanzanian infants. Lancet 1997;350(9081):844-50
   PubMed Web of Science ®Google Scholar
• Pringle G, Avery-Jones S. Observations on the early course of untreated falciparum malaria in semi-immune African children following a short period of protection. Bull World Health Organ 1966;34(2):269-72
   PubMed Web of Science ®Google Scholar
• Hogh B, Thompson R, Lobo V, The influence of maloprim chemoprophylaxis on cellular and humoral immune responses to plasmodium falciparum asexual blood stage antigens in schoolchildren living in a malaria endemic area of Mozambique. Acta Trop 1994;57(4):265-77
   PubMed Web of Science ®Google Scholar
• Greenwood BM, Greenwood AM, Smith AW, A comparative study of lapudrine (chlorproguanil) and maloprim (pyrimethamine and dapsone) as chemoprophylactics against malaria in Gambian children. Trans R Soc Trop Med Hyg 1989;83(2):182-8
   PubMed Web of Science ®Google Scholar
• Greenwood BM, David PH, Otoo-Forbes LN, Mortality and morbidity from malaria after stopping malaria chemoprophylaxis. Trans R Soc Trop Med Hyg 1995;89(6):629-33
   PubMed Web of Science ®Google Scholar
• Laing AB. The impact of malaria chemoprophylaxis in Africa with special reference to Madagascar, Cameroon, and Senegal. Bull World Health Organ 1984;62(Suppl):41-8
   PubMedGoogle Scholar
• Grobusch MP, Gabor JJ, Aponte JJ, No rebound of morbidity following intermittent preventive sulfadoxine-pyrimethamine treatment of malaria in infants in Gabon. J Infect Dis 2009;200(11):1658-61
   PubMed Web of Science ®Google Scholar
• Quelhas D, Puyol L, Quinto L, Impact of intermittent preventive treatment with sulfadoxine-pyrimethamine on antibody responses to erythrocytic-stage plasmodium falciparum antigens in infants in Mozambique. Clin Vaccine Immunol 2008;15(8):1282-91
   PubMedGoogle Scholar
• Rosen JB, Breman JG. Malaria intermittent preventive treatment in infants, chemoprophylaxis, and childhood vaccinations. Lancet 2004;363(9418):1386-8
   PubMed Web of Science ®Google Scholar
• Rosen JB, Breman JG, Manclark CR, Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines. Malar J 2005;4:53
   PubMed Web of Science ®Google Scholar
• World Health Organization. Report of the Technical Consultation on Intermittent Preventive Treatment in Infants (IPTi), Technical Expert Group on Preventive Chemotherapy. WHO/HQ; Geneva, Switzerland: 2009
   Google Scholar
• Rasheed FN, Bulmer JN, De Francisco A, Relationships between maternal malaria and malarial immune responses in mothers and neonates. Parasite Immunol 1995;17(1):1-10
   PubMed Web of Science ®Google Scholar
• Serra-Casas E, Menendez C, Bardaji A, The effect of intermittent preventive treatment during pregnancy on malarial antibodies depends on HIV status and is not associated with poor delivery outcomes. J Infect Dis 2009;201(1):123-31
   Web of Science ®Google Scholar
• Xi G, Leke RG, Thuita LW, Congenital exposure to plasmodium falciparum antigens: prevalence and antigenic specificity of in utero-produced antimalarial immunoglobulin M antibodies. Infect Immun 2003;71(3):1242-6
   PubMed Web of Science ®Google Scholar
• Broen K, Brustoski K, Engelmann I, Luty AJ. Placental plasmodium falciparum infection: causes and consequences of in utero sensitization to parasite antigens. Mol Biochem Parasitol 2007;151(1):1-8
   PubMed Web of Science ®Google Scholar
• Dembo EG, Mwapasa V, Montgomery J, Impact of human immunodeficiency virus infection in pregnant women on variant-specific immunity to malaria. Clin Vaccine Immunol 2008;15(4):617-21
   PubMed Web of Science ®Google Scholar
• Serra-Casas E, Menendez C, Bardaji A, The effect of intermittent preventive treatment during pregnancy on malarial antibodies depends on HIV status and is not associated with poor delivery outcomes. J Infect Dis 2010;201(1):123-31
   PubMed Web of Science ®Google Scholar
• Egan A, Crawley J, Schellenberg D. Intermittent preventive treatment for malaria control in infants: moving towards evidence-based policy and public health action. Trop Med Int Health 2005;10(9):815-17
   PubMed Web of Science ®Google Scholar
• Mockenhaupt FP, Bedu-Addo G, Eggelte TA, Rapid increase in the prevalence of sulfadoxine-pyrimethamine resistance among plasmodium falciparum isolated from pregnant women in Ghana. J Infect Dis 2008;198(10):1545-9
   PubMed Web of Science ®Google Scholar
• Roper C, Pearce R, Bredenkamp B, Antifolate antimalarial resistance in southeast Africa: a population-based analysis. Lancet 2003;361(9364):1174-81
   PubMed Web of Science ®Google Scholar
• Kublin JG, Dzinjalamala FK, Kamwendo DD, Molecular markers for failure of sulfadoxine-pyrimethamine and chlorproguanil-dapsone treatment of plasmodium falciparum malaria. J Infect Dis 2002;185(3):380-8
   PubMed Web of Science ®Google Scholar
• Schellenberg D, Kahigwa E, Drakeley C, The safety and efficacy of sulfadoxine-pyrimethamine, amodiaquine, and their combination in the treatment of uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg 2002;67(1):17-23
   PubMed Web of Science ®Google Scholar
• Mockenhaupt FP, Ehrhardt S, Dzisi SY, A randomized, placebo-controlled, double-blind trial on sulfadoxine-pyrimethamine alone or combined with artesunate or amodiaquine in uncomplicated malaria. Trop Med Int Health 2005;10(6):512-20
   PubMed Web of Science ®Google Scholar
• Abacassamo F, Enosse S, Aponte JJ, Efficacy of chloroquine, amodiaquine, sulphadoxine-pyrimethamine and combination therapy with artesunate in Mozambican children with non-complicated malaria. Trop Med Int Health 2004;9(2):200-8
   PubMed Web of Science ®Google Scholar
• Alloueche A, Bailey W, Barton S, Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial. Lancet 2004;363(9424):1843-8
   PubMed Web of Science ®Google Scholar
• Oduro AR, Anyorigiya T, Hodgson A, A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana. Trop Med Int Health 2005;10(3):279-84
   PubMed Web of Science ®Google Scholar
• Grobusch MP, Egan A, Gosling RD, Newman RD. Intermittent preventive therapy for malaria: progress and future directions. Curr Opin Infect Dis 2007;20(6):613-20
   PubMed Web of Science ®Google Scholar
• Menendez C, Serra-Casas E, Scahill MD, HIV and placental infection modulate the appearance of drug-resistant plasmodium falciparum in pregnant women who receive intermittent preventive treatment. Clin Infect Dis 2011;52(1):41-8
   PubMed Web of Science ®Google Scholar
• Faye B, Ndiaye M, Ndiaye JL, Prevalence of molecular markers of plasmodium falciparum resistance to sulfadoxine-pyrimethamine during the intermittent preventive treatment in infants coupled with the expanded program immunization in Senegal. Parasitol Res 2011;109(1):133-8
   PubMed Web of Science ®Google Scholar
• Dicko A, Sagara I, Djimde AA, Molecular markers of resistance to sulphadoxine-pyrimethamine one year after implementation of intermittent preventive treatment of malaria in infants in Mali. Malar J 2010;9:9
   PubMed Web of Science ®Google Scholar
• Harrington WE, Mutabingwa TK, Kabyemela E, Intermittent treatment to prevent pregnancy malaria does not confer benefit in an area of widespread drug resistance. Clin Infect Dis 2011;53(3):224-30
   PubMed Web of Science ®Google Scholar
• ter Kuile FO, van Eijk AM, Filler SJ. Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: a systematic review. JAMA 2007;297(23):2603-16
   PubMed Web of Science ®Google Scholar
• Kalanda GC, Hill J, Verhoeff FH, Brabin BJ. Comparative efficacy of chloroquine and sulphadoxine–pyrimethamine in pregnant women and children: a meta-analysis. Trop Med Int Health 2006;11(5):569-77
   PubMed Web of Science ®Google Scholar
• Tagbor H, Bruce J, Browne E, Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. Lancet 2006;368(9544):1349-56
   PubMed Web of Science ®Google Scholar
• O'Meara WP, Smith DL, McKenzie FE. Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malaria. PLoS Med 2006;3(5):e141
   Web of Science ®Google Scholar
• Report of the Technical Expert Group (TEG). Meeting on Intermittent Preventive Therapy in Infancy (IPTi), Geneva, 8-10 October 2007. Available from: http://malaria.who.int/docs/IPTi/TEGConsultIPTiOct2007Report.pdf
   Google Scholar
• MacArthur J, Stennies GM, Macheso A, Efficacy of mefloquine and sulfadoxine-pyrimethamine for the treatment of uncomplicated plasmodium falciparum infection in Machinga District, Malawi, 1998. Am J Trop Med Hyg 2001;65(6):679-84
   PubMed Web of Science ®Google Scholar
• Matteelli A, Saleri N, Bisoffi Z, Mefloquine versus quinine plus sulphalene-pyrimethamine (metakelfin) for treatment of uncomplicated imported falciparum malaria acquired in Africa. Antimicrob Agents Chemother 2005;49(2):663-7
   PubMed Web of Science ®Google Scholar
• Adam I, Ali DA, Alwaseila A, Mefloquine in the treatment of falciparum malaria during pregnancy in Eastern Sudan. Saudi Med J 2004;25(10):1400-2
   PubMed Web of Science ®Google Scholar
• Aubouy A, Fievet N, Bertin G, Dramatically decreased therapeutic efficacy of chloroquine and sulfadoxine-pyrimethamine, but not mefloquine, in southern Benin. Trop Med Int Health 2007;12(7):886-94
   PubMed Web of Science ®Google Scholar
• AlKadi HO. Antimalarial drug toxicity: a review. Chemotherapy 2007;53(6):385-91
   PubMed Web of Science ®Google Scholar
• Weinke T, Trautmann M, Held T, Neuropsychiatric side effects after the use of mefloquine. Am J Trop Med Hyg 1991;45(1):86-91
   PubMed Web of Science ®Google Scholar
• Nosten F, Vincenti M, Simpson J, The effects of mefloquine treatment in pregnancy. Clin Infect Dis 1999;28(4):808-15
   PubMed Web of Science ®Google Scholar
• Steketee RW, Wirima JJ, Slutsker L, Malaria parasite infection during pregnancy and at delivery in mother, placenta, and newborn: efficacy of chloroquine and mefloquine in rural Malawi. Am J Trop Med Hyg 1996;55(1 Suppl):24-32
   PubMed Web of Science ®Google Scholar
• Ward SA, Sevene EJ, Hastings IM, Antimalarial drugs and pregnancy: safety, pharmacokinetics, and pharmacovigilance. Lancet Infect Dis 2007;7(2):136-44
   PubMed Web of Science ®Google Scholar
• Phillips-Howard PA, Steffen R, Kerr L, Safety of mefloquine and other antimalarial agents in the first trimester of pregnancy. J Travel Med 1998;5(3):121-6
   PubMed Web of Science ®Google Scholar
• ter Kuile FO, Nosten F, Thieren M, High-dose mefloquine in the treatment of multidrug-resistant falciparum malaria. J Infect Dis 1992;166(6):1393-400
   PubMed Web of Science ®Google Scholar
• ter Kuile FO, Nosten F, Luxemburger C, Mefloquine treatment of acute falciparum malaria: a prospective study of non-serious adverse effects in 3673 patients. Bull World Health Organ 1995;73(5):631-42
   PubMed Web of Science ®Google Scholar
• Clerk CA, Bruce J, Affipunguh PK, A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. J Infect Dis 2008;198(8):1202-11
   PubMed Web of Science ®Google Scholar
• Nosten F, McGready R, d'Alessandro U, Antimalarial drugs in pregnancy: a review. Curr Drug Saf 2006;1(1):1-15
   PubMedGoogle Scholar
• Rahangdale L, Guerry S, Bauer HM, An observational cohort study of Chlamydia trachomatis treatment in pregnancy. Sex Transm Dis 2006;33(2):106-10
   PubMed Web of Science ®Google Scholar
• Van Vranken M. Prevention and treatment of sexually transmitted diseases: an update. Am Fam Physician 2007;76(12):1827-32
   PubMed Web of Science ®Google Scholar
• WHO. WHO guidelines for the treatment of malaria. World Health Organization WHM; Geneva: 2010; WHO/HTM/MAL
   Google Scholar
• Nosten F, McGready R, Mutabingwa T. Case management of malaria in pregnancy. Lancet Infect Dis 2007;7(2):118-25
   PubMed Web of Science ®Google Scholar
• McGready R, Cho T, Keo NK, Artemisinin antimalarials in pregnancy: a prospective treatment study of 539 episodes of multidrug-resistant plasmodium falciparum. Clin Infect Dis 2001;33(12):2009-16
   PubMed Web of Science ®Google Scholar
• Sokhna C, Cisse B, Ba el H, A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children. PLoS One 2008;3(1):e1471
   Web of Science ®Google Scholar
• Worrall E, Morel C, Yeung S, The economics of malaria in pregnancy–a review of the evidence and research priorities. Lancet Infect Dis 2007;7(2):156-68
   PubMed Web of Science ®Google Scholar
• Goodman CA, Coleman PG, Mills AJ. Cost-effectiveness of malaria control in sub-Saharan Africa. Lancet 1999;354(9176):378-85
   PubMed Web of Science ®Google Scholar
• Goodman CA, Coleman PG, Mills AJ. The cost-effectiveness of antenatal malaria prevention in sub-Saharan Africa. Am J Trop Med Hyg 2001;64(1-2 Suppl):45-56
   PubMed Web of Science ®Google Scholar
• Schultz LJ, Steketee RW, Chitsulo L, Wirima JJ. Antimalarials during pregnancy: a cost-effectiveness analysis. Bull World Health Organ 1995;73(2):207-14
   PubMed Web of Science ®Google Scholar
• Schultz LJ, Steketee RW, Chitsulo L, Evaluation of maternal practices, efficacy, and cost-effectiveness of alternative antimalarial regimens for use in pregnancy: chloroquine and sulfadoxine-pyrimethamine. Am J Trop Med Hyg 1996;55(1 Suppl):87-94
   PubMed Web of Science ®Google Scholar
• Breman JG, Mills A, Snow RW, Conquering malaria. Chapter 21 in Disease control priorities in developing countries. World Bank and Oxford University Press: Washington; 2006
   Google Scholar
• Mbonye AK, Hansen KS, Bygbjerg IC, Magnussen P. Intermittent preventive treatment of malaria in pregnancy: the incremental cost-effectiveness of a new delivery system in Uganda. Trans R Soc Trop Med Hyg 2008;102(7):685-93
   PubMed Web of Science ®Google Scholar
• Hill J, Kazembe P. Reaching the Abuja target for intermittent preventive treatment of malaria in pregnancy in African women: a review of progress and operational challenges. Trop Med Int Health 2006;11(4):409-18
   PubMed Web of Science ®Google Scholar
• Crawley J, Hill J, Yartey J, From evidence to action? Challenges to policy change and programme delivery for malaria in pregnancy. Lancet Infect Dis 2007;7(2):145-55
   PubMed Web of Science ®Google Scholar
• Sicuri E, Bardaji A, Nhampossa T, Cost-effectiveness of intermittent preventive treatment of malaria in pregnancy in southern Mozambique. PLoS One 2010;5(10):e13407
   PubMed Web of Science ®Google Scholar
• Hutton G, Schellenberg D, Tediosi F, Cost-effectiveness of malaria intermittent preventive treatment in infants (IPTi) in Mozambique and the United Republic of Tanzania. Bull World Health Organ 2009;87(2):123-9
   PubMed Web of Science ®Google Scholar
• Conteh L, Sicuri E, Manzi F, The cost-effectiveness of intermittent preventive treatment for malaria in infants in Sub-Saharan Africa. PLoS ONE 2010;5(6):e10313
   Web of Science ®Google Scholar
• Ceesay SJ, Casals-Pascual C, Erskine J, Changes in malaria indices between 1999 and 2007 in the Gambia: a retrospective analysis. Lancet 2008;372(9649):1545-54
   PubMed Web of Science ®Google Scholar
• O'Meara WP, Bejon P, Mwangi TW, Effect of a fall in malaria transmission on morbidity and mortality in Kilifi, Kenya. Lancet 2008;372(9649):1555-62
   PubMed Web of Science ®Google Scholar
• WHO. World health organization. The World malaria Report; Geneva, Switzerland: 2010
   Google Scholar
• Feng G, Simpson JA, Chaluluka E, Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets. PLoS One 2010;5(8):e12012
   Web of Science ®Google Scholar
• Garner P, Gulmezoglu AM. Drugs for preventing malaria in pregnant women. Cochrane Database Syst Rev 2006(4):CD000169
   PubMed Web of Science ®Google Scholar
• Greenwood B. Anti-malarial drugs and the prevention of malaria in the population of malaria endemic areas. Malar J 2010;9(Suppl 3):S2
   PubMed Web of Science ®Google Scholar
• Gosling RD, Cairns ME, Chico RM, Chandramohan D. Intermittent preventive treatment against malaria: an update. Expert Rev Anti Infect Ther 2010;8(5):589-606
   PubMed Web of Science ®Google Scholar
• Tagbor H, Bruce J, Agbo M, Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: a randomised controlled non-inferiority trial. PLoS One 2011;5(12):e14425
   Web of Science ®Google Scholar
• Martinez-Espinosa FE, Daniel-Ribeiro CT, Alecrim WD. Malaria during pregnancy in a reference centre from the Brazilian Amazon: unexpected increase in the frequency of Plasmodium falciparum infections. Mem Inst Oswaldo Cruz 2004;99(1):19-21
   PubMed Web of Science ®Google Scholar
• Rodriguez-Morales AJ, Sanchez E, Vargas M, Pregnancy outcomes associated with plasmodium vivax malaria in northeastern Venezuela. Am J Trop Med Hyg 2006;74(5):755-7
   PubMed Web of Science ®Google Scholar
• Nosten F, McGready R, Simpson JA, Effects of plasmodium vivax malaria in pregnancy. Lancet 1999;354(9178):546-9
   PubMed Web of Science ®Google Scholar
• Singh N, Shukla MM, Sharma VP. Epidemiology of malaria in pregnancy in central India. Bull World Health Organ 1999;77(7):567-72
   PubMed Web of Science ®Google Scholar
• Singh N, Saxena A, Shrivastava R. Placental Plasmodium vivax infection and congenital malaria in central India. Ann Trop Med Parasitol 2003;97(8):875-8
   PubMed Web of Science ®Google Scholar
• Lengeler C. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev 2004(2):CD000363
   Google Scholar
• Alonso PL, Sacarlal J, Aponte JJ, Efficacy of the RTS,S/AS02A vaccine against plasmodium falciparum infection and disease in young African children: randomised controlled trial. Lancet 2004;364(9443):1411-20
   PubMed Web of Science ®Google Scholar
• Griffin JT, Cairns M, Ghani AC, Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance. PLoS One 2010;5(9):e12618
   Web of Science ®Google Scholar
• Alexander N, Sutherland C, Roper C, Modelling the impact of intermittent preventive treatment for malaria on selection pressure for drug resistance. Malar J 2007;6:9
   PubMed Web of Science ®Google Scholar
• Cisse B, Sokhna C, Boulanger D, Seasonal intermittent preventive treatment with artesunate and sulfadoxine-pyrimethamine for prevention of malaria in Senegalese children: a randomised, placebo-controlled, double-blind trial. Lancet 2006;367(9511):659-67
   PubMed Web of Science ®Google Scholar
• Greenwood B. Review: intermittent preventive treatment–a new approach to the prevention of malaria in children in areas with seasonal malaria transmission. Trop Med Int Health 2006;11(7):983-91
   PubMed Web of Science ®Google Scholar