62
Views
3
CrossRef citations to date
0
Altmetric
Review

Cost of cancer clinical trials in elderly patients

Pages 505-511 | Published online: 02 Mar 2005

Bibliography

  • YANCIK RM, PIES L: Cancer and age: magnitude of the problem. In: Comprehensive Geriatric Oncology Balducci L, Lyman GH, Ershler WB. Harwood Academic Publishers, London, (1998).
  • REPETTO L, BALDUCCI L: A case for geriatric oncology. Lancet Oncol (2002) 3(5):289–297.
  • ANONYMOUS: Integrating economic analysis into cancer clinical trials: the National Cancer Institute - American Society of Clinical Oncology workbook. J. Natl. Cancer Inst. Monographs (1998) 24:1–28.
  • ROBINSON B: Cost of anemia in the elderly. J. Am. Get: Soc. (2003)51(3 Suppl.):S14–S17.
  • LUBITZ J, CAI L, KRAMAROW E et al: Health, life-expectancy and health care spending among the elderly. N Engl. J. Med. (2003) 349:1048–1055.
  • BALDUCCI L, HARDY CL,LYMAN GH: Hematopoietic growth factors in the older cancer patient.Carr. Opin. Hematol (2001) 8(3):170–187.
  • HAYMAN JA, LANGA KM,KABETO MU et al.: Estimating the cost of informal caregiving for elderly patients with Cancer. J Clin. Oncol (2001) 19:3219–3225.
  • SOLDO BJ, HURD MD, RODGERS WL et al.: Asset and health dynamics among the oldest old: an overview of the AHEAD Study. J. Gerontol B Psychol Sci. Soc. Sci. (1997) 52B:1–20.
  • HALEY WE, BURTON AM,LAMONDE LA, SCHON WETTER RS:Family caregiving for older cancer patients.In: Comprehensive geriatric oncology (2'd edh). Balducci L, Lyman GH, Ershler WB, Extermann M (Eds.), Harwood Academic Publishers, London (In Press).
  • HALEY WE, BURTON AM,LAMONDE LA, SCHONWETTER RS: Predictors of depression and life satisfaction among spousal caregivers in hospice: application of a stress process model.Pa/hat. Med. (2003) 6:215–224.
  • OVERCASH J, BALDUCCI L: The older cancer patient: a guide for nurses and related professionals. Springer Publishing Company, New York, USA (2003).
  • GOODWIN PJ, SHEPHERD FA: Economic issues in lung cancer: a review. Chin. Oncol (1998) 16:3900–3912.
  • FISHER RI, GAYNOR ER, DAHLBER S et al: Comparison of a standard regimen (CHOP) with three intensive chemotherapy regimens for advanced Non Hodgkin's Lymphoma. N Engl J. Med. (1993) 318:1002–1006.
  • TALLMAN MS, GRAY R, ROBERT NJ et al: Conventional adjuvant chemotherapy with or without high dose chemotherapy and autologous stem cell rescue in high risk breast cancer. N Engl J. Med. (2003) 349:17–26.
  • BENNETT CL, ADAMS JR, KNOX KS et al: Clinical Trials: are they a good buy? Chin. Oncol (2001) 19:4330–4339.
  • DU W, REEVES JH, GADGEEL S et a/.: Cost-effectiveness and lung cancer clinical trials. Cancer (2003) 98:1491–1496.
  • BENNETT CL, STINTS ON TJ, VOGEL V et al.: Evaluating the financial impacts of clinical trials in oncology: results from a pilot study from the association ofAmerican Cancer Institutes. J. Chin. Oncol.(2000) 18:2805–2810.
  • FIREMAN BH, FEHERENBACHER L, GRUSKIN EP et al: Cost of care for patients in cancer clinical trials. Nati Cancer Inst. (2000) 92:136–142.
  • GOLDMAN DP, BERRY SH, MCCABE MS et al.: Incremental Treatment costs in national cancer institute-sponsored clinical trials. JAMA (2003) 289(22):2970–2977.
  • ANONYMOUS: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced colorectal Cancer meta-analysis. J. Chin. Oncol (1992) 10:896–903.
  • KHANSUR T, HAICK A, PATEL B et al:Preoperative evaluation with radionuclide brain scanning and computerized Axial Tomography of the brain in patients with breast cancer. Am. J. Surg. (1988) 155:232–234.
  • EXTERMANN M, BALDUCCI L, LYMAN GH: What threshold for adjuvant therapy in older breast cancer patients? Chin. Oncol (2000) 18:1709–1717.
  • MORRISON VA, PICOZZI V, SCOTTI Set al.: The impact of age on delivered dose-intensity and hospitalizations for febrile neutropenia in patients with intermediate-grade non-Hodgkin's Lymphoma receiving initial CHOP chemotherapy: a risk factor analysis. Chin. Lymphoma (2001) 2:47–56.
  • CHRISCHILLES E, DELGADO DI, STOLSHEK BS et al.: Impact of age and colony stimulating factor use in hospital length of stay for febbrile neutropenia in CHOP treated non-Hodgkin's lymphoma patients. Cancer Control (2002) 9:203–211.
  • REPETTO L, FRATINO L, AUDISIO RA et al: Comprehensive geriatric assessment adds information to the Eastern Cooperative Group performance status in elderly cancer patients. An Italian Group for Geriatric Oncology Study. I Clin. Oncol (2002) 20:494–502.
  • INGRAM SS, SEO PH, MARTELL RE et al.: Comprehensive assessment of the elderly cancer patient: the feasibility of self-report methodology. J. Clin. Oncol (2002) 20:770–775.
  • EXTERMANN M, OVERCASH J, LYMAN GH et al.: Comorbidity and functional status are independent in older cancer patients. " Clin. Oncol (1998) 16:1582–1587.
  • SALIBA D, ELLIOTT M,RUBENSTEIN LZ et al.: The Vulnerable Elders Survey: a tool for identifying vulnerable older people in the community. J. Am. Ger. Soc. (2001) 49:1691–1699.
  • PODSIADLO D AND RICHARDSON S: The timed 'up & go': a test of basic functional mobility for frail elderly persons. J. Am. Ger. Soc. (1991) 39:142–148.
  • RINK L, CA KMAN I, KIRCHNER H: Altered cytokine production in the elderly. Mech. Ageing Dev. (1998) 102:199–209.
  • COHEN HJ, HARRIS T, PIEPER CF: Coagulation and activation of the inflammation pathway in the development of functional decline and mortality in the elderly. Arn. J. Med. (2003) 114:180–187.
  • EMANUEL E: Health care reform: still possible? Hastings Center Rep. (2002) 32:32–34.
  • BEGG CB, CARBONE P: Clinical trials and drug toxicity in the elderly. The experience of the Eastern Cooperative Oncology Group. Cancer (1983) 52:1986–1992.
  • HUTCHINS LF, UNGER JM, CROWLEY JJ et al.: Underrepresentation fo patients 65 year of age or older in cancer treatment trials. N Engl. J. Med. (1999) 341:2061–2067.
  • LEWIS JH, KILGORE ML,GOLDMAN DP et al.: Participation of patients 65 year of age and older in cancer clinical trials. " Clin. Oncol (2003) 21:1383–1388.
  • KEMENY MN, PETERSON BL, KOMBLITH AB et al.: Barriers to clinical trial participation by older women with breast cancer." Clin. Oncol (2003) 21:2269–2279.
  • ZINZANI PG, STORTI S, ZACCARIA A et al.: Elderly aggressive histology Non-Hodgkin's Lymphoma: first line VNCOP-B regimen: expereince on 350 patients. Blood (1999) 94:33–38.
  • SONNEVELD P, DE RIDDER M, VAN DER LELIE H et al.: Comparison of doxorubicin and mitoxantrone in the treatment of elderly patients with advanced diffuse non-Hodgkin's lymphoma using CHOP versus CNOP chemotherapy.Clin Oncol (1995) 13:2530–2539.
  • TIRELLI TIRELLI U, ERRANTE D, VAN GLABBEKE M et al.: CHOP is the standard regimen in patients 70 years of age with intermediate and high grade Non-Hodgkin's lymphoma: results of a randomized study of the European organization for the Research and Treatment of Cancer Lymphoma Cooperative Study." Clin. Oncol (1998) 16:27–34.
  • BASTION Y, BLAY J-Y, DIVINE M et al.:Elderly patients with aggressive non-Hodgkin's lymphoma: disease presentation, response to treatment and survival. A Groupe d'Etude des Lymphomes de l'Adulte Study on 453 patients older than 69 years.," Clin. Oncol (1997) 15:2945–2953.
  • OSBY E, HAGBERG H, KVALOY S et al.:CHOP is superior to CNOP in elderly patients with aggressive lymphoma while outcome is unaffected by filgrastim treatment: results of a Nordic Lymphoma Group randomized trial. Blood (2003) 101:3840–3848.
  • LANCET JE, Willman CL, Bennett JM:Acute Myelogenous Leukemia and aging: Clinical Interactions. Hematol/Oncol Clinics N America (2000) 16:251–268.
  • HAYMAN J, SCHNITT S, GELMAN R et al.: A prospective trial of conservative surgery (CS) alone without radiation therapy (RT) in selected patients with early stage breast cancer. Int. .1. Radiat. Oncol Biol. Phys. (1995) 32\(Suppl. 1):209.
  • VVYCKOFF J, GREENBERG H, SANDERSON R et al.: Breast irradiation in the older woman: a toxicity study." Am. Ger. Soc. (1994) 42:153–156.
  • MORROW M, HARRIS JR,SCHNITT SJ: Local control following breast cancer conserving surgery: results of clinical trials." Natl. Cancer Inst. (1995) 87:1669–1673.
  • WOLMAKR N, DIGNAM J, MARGOLESED et al.: The role of radiotherapy and tamoxifen in the management of node-negative breast cancer - 1.0 cm treated with lumpectomy: preliminary results of NSABP protocol B21. Proc. ASCO (2000) 19:70a (Abstract 271).
  • MUSTACCHI G, MILANI S,PLUCHINOTTA A: Tamoxifen or surgery plus tamoxifen as primary treatment for elderly patients with operable breast cancer: The G.R.E.T.A. Trial. Group for Research on Endocrine Therapy in the Elderly. Anticancer Res (1994) 14(5B):2197–2200.
  • BALDUCCI L: Pain management in elderlycancer patients. J. Sapp. Oncol (2003).
  • SMITH TJ, ROTHEMBERG SS, BROOKS M et al: Randomized clinical trial of an implantable drug delivery system compared with comprehensive medical management for cancer pain: impact on pain, drug-related toxicity, and survival.Oncol (2002) 20:4040–4049.
  • RAVDIN PM; SMIRNOFF LA,DAVIS GJ et al.: Computer program to assist in making decisions about adjuvant therapy for women with early breast cancer.Oncol (2001) 19:980–981.
  • LYMAN GH, KUDERER N,AGBOOLA 0 et al.: Evidence-based use of colony-stimulating factors in elderly cancer patients. Cancer Control (2003)a10:487–499.

website

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.