XI Congress of the International Headache Society

Bibliography

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• •This review summarises the most important findings concerning the pathophysiological mechanisms of migraine obtained with electrophysiological methods. Particular emphasis was given to the results supporting a lack of habituation in the interictal period, as the main abnormality of sensory processing in migraineurs emerged from studies by visual and auditory evoked potential and those of central trigeminal pathways. The findings of habituation of pattern-reversal visual evoked potentials exploring changes induced by repeated transcranial stimulation favour the hypothesis of a decreased level of preactivation excitability.
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• ••This original article furnishes the evidencebased on an experimental migraine model which establishes a link between migraine aura and headache. In this model, cortical spreading depression, implicated in migraine visual aura, was demonstrated to activate trigeminovascular afferents and evoke a series of cortical meningeal and brainstem events consistent with the development of headache.
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• •This review illustrates migraine equivalents of infancy, childhood and adolescence, which include recognised periodic, paroxysmal syndromes without associated headache, that are thought to be migrainous in aetiology. Five such equivalents are presently recognised. Their clinical features and relative frequency in ambulatory paediatric neurology practice are described, although the evidence is not numerous.
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• SARCHIELLI P, ALBERTI A, GALLAI B, BALDI A, MAZZOTTA G: NF-kB and inducible nitric oxide synthase mRNA and protein expression in monocytes from internal jugular venous blood of migraine without aura patients assessed during attacks. Abstracts of the XI Congress of the International Headache Society/IHC 2003. iCephalalgia i (2003) 23(7):573.
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• REUTER U, CHIARUGI A, BOLAY H, MOSKOWITZ MA: Nuclear factor-kappaB as a molecular target for migraine therapy. iAnn. Neurol. i (2002) 51(4):507–516.
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• •This original paper supports the role played by NF-x_13 in migraine using a model of delayed inflammation induced by an NO donor. This could be relevant for the development of new therapeutic strategies to explain the mechanisms of action of already proven drugs for migraine, such as parthenolide and acetylsalicylic acid.
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• •This original paper reports the results of the measurement of metabolite levels in the cerebellum by MRS and demonstrated reduced levels of choline in migraine patients with aura compared to an age-matched control group.
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• ••This review examined the fmdings ofmissense mutations in the iCACNA1A i and iATP1A i genes related to FHM on chromosomes 19q13 and 1q2 genes, respectively; additional migraine genes were identified for the more common and genetically complex forms of migraine; and also certain polymorphisms associated with migraine, including those associated with some comorbid diseases, such as depression and bipolar disturbance.
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• VANMOLKOT KRJ, KORS EE, HOTTENGA J iet al.: i Novel mutations in the Na*, K'-ATPase pump gene ATP1A2 in Familial Hemiplegic Migraine. Abstracts of the XI Congress of the International Headache Society/IHC 2003. iCephalalgia i (2003) 23(7):576.
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• ••This is the largest meta-analysis studycarried out for the comparison of the oral triptan formulations. Efficacy parameters, consistency data, headache recurrence and tolerability were examined.
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• ••This letter is the first evidence of the efficacy of deep-brain stimulation of the ipsilateral posterior inferior hypothalamus for the treatment of severe, intractable chronic CH, based on recent emission tomography and functional MRI studies, which have demonstrated hypothalamic activation during CH attacks.
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• MAYA, LEONE M: Update on cluster headache. iCup: Opin. Neural i (2003) 16(3):333–340.
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• D'ANDREA G, LEON B, PERINI F, FORTINI D, BUSSONE G: Abnormal elusive amine levels in cluster headache. Abstracts of the XI Congress of the International Headache Society/IHC 2003. iCephalalgia i (2003) 23(7):580.
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• EKBOM K, SJOSTRAND C, SVENSSON DA, WALDENLIND E: Periods of cluster headache induced by nitrate therapy and spontaneous remission of angina pectoris during active clusters. Abstracts of the XI Congress of the International Headache Society/IHC 2003. iCephalalgia i (2003) 23(7):580.
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• MATHARU M, LEVY M, MEERAN K, GOADSBY P: Subcutaneous octreotide is effective in the treatment of acute cluster headache: a double-blind placebo-controlled crossover study. Abstracts of the XI Congress of the International Headache Society/IHC 2003. iCephalalgia i (2003) 23(7):580.
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• OLESEN J: ICHD-II: the new IHS classification of headaches. Abstracts of the XI Congress of the International Headache Society/IHC 2003. iCephalalgia i (2003) 23(7):567.
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• HEADACHE CLASSIFICATION COMMITTEE OF THE INTERNATIONAL HEADACHE SOCIETY: Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. iCephalalgia i (1988) 8\(Suppl. 7):1–96.
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• HEADACHE CLASSIFICATION SUBCOMMITTEE OF THE INTERNATIONAL HEADACHE SOCIETY: The International Classification of Headache Disorders (2"d edn). iCephalalgia i (2004) 24\(Supp1.1):1–160.
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• ••This refers to the new, recently publishedclassification system for primary and secondary headaches. Affiliation Paola Sarchielli Department of Neuroscience, Neurologic Clinic, University of Perugia, Via Enrico dal Pozzo -06126 Perugia, Italy Tel: +39 075 578 3609; Fax: +39 075 578 3870; E-mail: [email protected]
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