Allogenic bone-marrow-derived mesenchymal stem cells transplantation as a novel therapy for systemic lupus erythematosus

Bibliography

• Arbuckle MR, McClain MT, Rubertone MV, Development of autoantibodies before the clinical onset of systemic lupus erythematosus. N Engl J Med 2003;10:1526-33
   Web of Science ®Google Scholar
• Jacobi AM, Zhang J, Mackay M, Phenotypic characterization of autoreactive B cells-checkpoints of B cell tolerance in patients with systemic lupus erythematosus. PLoS One 2009;4:e5776
   PubMed Web of Science ®Google Scholar
• Foster MH, Kelley VR. Lupus nephritis: update on pathogenesis and disease mechanisms. Semin Nephrol 1999;19:173-81
   PubMed Web of Science ®Google Scholar
• Wong CK, Ho CY, Li EK, Lam CW. Elevation of proinflammatory cytokine (IL-18, IL-17, IL-12) and Th2 cytokine (IL-4) concentrations in patients with systemic lupus erythematosus. Lupus 2000;9:589-93
   PubMed Web of Science ®Google Scholar
• Horwitz DA, Gray JD, Behrendsen SC, Decreased production of interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus. Arthritis Rheum 1998;41:838-44
   PubMed Web of Science ®Google Scholar
• Austin HA III, Klippel JH, Balow JE, Therapy of lupus nephritis. Controlled trial of prednisone and cytotoxic drugs. N Engl J Med 1986;314:614-19
   PubMed Web of Science ®Google Scholar
• Chan TM, Li FK, Tang CS, Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. N Engl J Med 2000;343:1156-62
   PubMed Web of Science ®Google Scholar
• Bernatsky S, Boivin JF, Joseph L, Mortality in systemic lupus erythematosus. Arthritis Rheum 2006;54:2550-7
   PubMed Web of Science ®Google Scholar
• Ramos-Casals M, Diaz-Lagares C, Khamashta MA. Rituximab and lupus: good in real life, bad in controlled trials. Comment on the article by Lu, et al. Arthritis Rheum 2009;61:1281-2
   PubMed Web of Science ®Google Scholar
• Ramos-Casals M, Soto MJ, Cuadrado MJ, Khamashta MA. Rituximab in systemic lupus erythematosus: a systematic review of off-label use in 188 cases. Lupus 2009;18:767-76
   PubMed Web of Science ®Google Scholar
• Goldenberg DM, Stein R, Leonard JP, B cell therapy with the anti-CD22 monoclonal antibody epratuzumab: comment on the editorial by St. Clair and Tedder. Arthritis Rheum 2006;54:2344, 2344-5
   PubMed Web of Science ®Google Scholar
• Alexander T, Thiel A, Rosen O, Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system. Blood 2009;113:214-23
   PubMed Web of Science ®Google Scholar
• Burt RK, Traynor A, Statkute L, Nonmyeloablative hematopoietic stem cell transplantation for systemic lupus erythematosus. Jama 2006;295:527-35
   PubMed Web of Science ®Google Scholar
• Rosen O, Thiel A, Massenkeil G, Autologous stem-cell transplantation in refractory autoimmune diseases after in vivo immunoablation and ex vivo depletion of mononuclear cells. Arthritis Res 2000;2:327-36
   PubMedGoogle Scholar
• Namendys-Silva SA, Baltazar-Torres JA, Rivero-Sigarroa E, Prognostic factors in patients with systemic lupus erythematosus admitted to the intensive care unit. Lupus 2009;18:1252-8
   PubMed Web of Science ®Google Scholar
• Burt RK, Traynor AE, Pope R, Treatment of autoimmune disease by intense immunosuppressive conditioning and autologous hematopoietic stem cell transplantation. Blood 1998;92:3505-14
   PubMed Web of Science ®Google Scholar
• Burt RK, Traynor A, Ramsey-Goldman R. Hematopoietic stem-cell transplantation for systemic lupus erythematosus. N Engl J Med 1997;337:1777-8
   PubMed Web of Science ®Google Scholar
• Nikolov NP, Pavletic SZ. Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. Nat Clin Pract Rheumatol 2008;4:184-91
   PubMedGoogle Scholar
• Hugle T, van Laar JM. Stem cell transplantation for rheumatic autoimmune diseases. Arthritis Res Ther 2008;10:217
   PubMed Web of Science ®Google Scholar
• Friedenstein AJ, Chailakhyan RK, Latsinik NV, Stromal cells responsible for transferring the microenvironment of the hemopoietic tissues. Cloning in vitro and retransplantation in vivo. Transplantation 1974;17:331-40
   PubMed Web of Science ®Google Scholar
• Le Blanc K, Frassoni F, Ball L, Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study. Lancet 2008;371:1579-86
   PubMed Web of Science ®Google Scholar
• Krampera M, Glennie S, Dyson J, Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003;101:3722-9
   PubMed Web of Science ®Google Scholar
• Uccelli A, Pistoia V, Moretta L. Mesenchymal stem cells: a new strategy for immunosuppression? Trends Immunol 2007;28:219-26
   PubMed Web of Science ®Google Scholar
• Chen X, Armstrong MA, Li G. Mesenchymal stem cells in immunoregulation. Immunol Cell Biol 2006;84:413-21
   PubMed Web of Science ®Google Scholar
• Yang M, Liu L. MHC II gene knockout in tissue engineering may prevent immune rejection of transplants. Med Hypotheses 2008;70:798-801
   PubMed Web of Science ®Google Scholar
• Theofilopoulos AN, Dixon FJ. Murine models of systemic lupus erythematosus. Adv Immunol 1985;37:269-390
   PubMed Web of Science ®Google Scholar
• Morton JI, Siegel BV. Transplantation of autoimmune potential. I. Development of antinuclear antibodies in H-2 histocompatible recipients of bone marrow from New Zealand Black mice. Proc Natl Acad Sci USA 1974;71:2162-5
   PubMed Web of Science ®Google Scholar
• Akizuki M, Reeves JP, Steinberg AD. Expression of autoimmunity by NZB/NZW marrow. Clin Immunol Immunopathol 1978;10:247-50
   PubMedGoogle Scholar
• Ikehara S, Good RA, Nakamura T, Rationale for bone marrow transplantation in the treatment of autoimmune diseases. Proc Natl Acad Sci USA 1985;82:2483-7
   PubMed Web of Science ®Google Scholar
• Ikehara S, Inaba M, Yasumizu R, Autoimmune diseases as stem cell disorders. Tohoku J Exp Med 1994;173:141-55
   PubMed Web of Science ®Google Scholar
• Sun L, Liang J, Li H, Hou Y. Polarization of T lymphocytes is regulated by mesenchymal stem cells in NZBWF1 and BALB/c mice. Int J Mol Sci 2007;8:455-69
   Web of Science ®Google Scholar
• El-Badri NS, Hakki A, Ferrari A, Autoimmune disease: is it a disorder of the microenvironment? Immunol Res 2008;41:79-86
   PubMed Web of Science ®Google Scholar
• Sun L, Akiyama K, Zhang H, Mesenchymal stem cell transplantation reverses multiorgan dysfunction in systemic lupus erythematosus mice and humans. Stem Cells 2009;27:1421-32
   PubMed Web of Science ®Google Scholar
• Papadaki HA, Boumpas DT, Gibson FM, Increased apoptosis of bone marrow CD34+ cells and impaired function of bone marrow stromal cells in patients with systemic lupus erythematosus. Br J Haematol 2001;115:167-74
   PubMed Web of Science ®Google Scholar
• Otsuka T, Nagasawa K, Harada M, Niho Y. Bone marrow microenvironment of patients with systemic lupus erythematosus. J Rheumatol 1993;20:967-71
   PubMed Web of Science ®Google Scholar
• Sun LY, Zhang HY, Feng XB, Abnormality of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Lupus 2007;16:121-8
   PubMed Web of Science ®Google Scholar
• Gu ZF, Zhao SN, Zhang HY, Characterization of the ultrastructure and cytoskeleton of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Chin J Rheumatol 2008;12:497-500
   Google Scholar
• Friedenstein AJ, Petrakova KV, Kurolesova AI, Frolova GP. Heterotopic of bone marrow. Analysis of precursor cells for osteogenic and hematopoietic tissues. Transplantation 1968;6:230-47
   PubMed Web of Science ®Google Scholar
• Kern S, Eichler H, Stoeve J, Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 2006;24:1294-301
   PubMed Web of Science ®Google Scholar
• Beyer Nardi N, da Silva Meirelles L. Mesenchymal stem cells: isolation, in vitro expansion and characterization. Handb Exp Pharmacol 2006;249-82
   PubMedGoogle Scholar
• Ulloa-Montoya F, Verfaillie CM, Hu WS. Culture systems for pluripotent stem cells. J Biosci Bioeng 2005;100:12-27
   PubMed Web of Science ®Google Scholar
• Majumdar MK, Keane-Moore M, Buyaner D, Characterization and functionality of cell surface molecules on human mesenchymal stem cells. J Biomed Sci 2003;10:228-41
   PubMed Web of Science ®Google Scholar
• Le Blanc K, Tammik C, Rosendahl K, HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 2003;31:890-6
   PubMed Web of Science ®Google Scholar
• Woodbury D, Schwarz EJ, Prockop DJ, Black IB. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000;61:364-70
   PubMed Web of Science ®Google Scholar
• Sanchez-Ramos J, Song S, Cardozo-Pelaez F, Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol 2000;164:247-56
   PubMed Web of Science ®Google Scholar
• Saulnier N, Lattanzi W, Puglisi MA, Mesenchymal stromal cells multipotency and plasticity: induction toward the hepatic lineage. Eur Rev Med Pharmacol Sci 2009;13(Suppl 1):71-8
   PubMed Web of Science ®Google Scholar
• Aggarwal S, Pittenger MF. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 2005;105:1815-22
   PubMed Web of Science ®Google Scholar
• Villaron EM, Almeida J, Lopez-Holgado N, Mesenchymal stem cells are present in peripheral blood and can engraft after allogeneic hematopoietic stem cell transplantation. Haematologica 2004;89:1421-7
   PubMed Web of Science ®Google Scholar
• Meirelles Lda S, Fontes AM, Covas DT, Caplan AI. Mechanisms involved in the therapeutic properties of mesenchymal stem cells. Cytokine Growth Factor Rev 2009;20:419-27
   PubMed Web of Science ®Google Scholar
• Djouad F, Charbonnier LM, Bouffi C, Mesenchymal stem cells inhibit the differentiation of dendritic cells through an interleukin-6-dependent mechanism. Stem Cells 2007;25:2025-32
   PubMed Web of Science ®Google Scholar
• Bernardo ME, Avanzini MA, Perotti C, Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell-therapy approaches: further insights in the search for a fetal calf serum substitute. J Cell Physiol 2007;211:121-30
   PubMed Web of Science ®Google Scholar
• Le Blanc K, Tammik L, Sundberg B, Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand J Immunol 2003;57:11-20
   PubMed Web of Science ®Google Scholar
• Maitra B, Szekely E, Gjini K, Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant 2004;33:597-604
   PubMed Web of Science ®Google Scholar
• Ye Z, Wang Y, Xie HY, Zheng SS. Immunosuppressive effects of rat mesenchymal stem cells: involvement of CD4+CD25+ regulatory T cells. Hepatobiliary Pancreat Dis Int 2008;7:608-14
   PubMed Web of Science ®Google Scholar
• Casiraghi F, Azzollini N, Cassis P, Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells. J Immunol 2008;181:3933-46
   PubMed Web of Science ®Google Scholar
• Di Ianni M, Del Papa B, De Ioanni M, Mesenchymal cells recruit and regulate T regulatory cells. Exp Hematol 2008;36:309-18
   PubMed Web of Science ®Google Scholar
• Selmani Z, Naji A, Zidi I, Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells. Stem Cells 2008;26:212-22
   PubMed Web of Science ®Google Scholar
• Tse WT, Pendleton JD, Beyer WM, Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 2003;75:389-97
   PubMed Web of Science ®Google Scholar
• Klyushnenkova E, Mosca JD, Zernetkina V, T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression. J Biomed Sci 2005;12:47-57
   PubMed Web of Science ®Google Scholar
• Rasmusson I, Ringden O, Sundberg B, Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003;76:1208-13
   PubMed Web of Science ®Google Scholar
• Munn DH, Zhou M, Attwood JT, Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998;281:1191-3
   PubMed Web of Science ®Google Scholar
• Jiang XX, Zhang Y, Liu B, Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells. Blood 2005;105:4120-6
   PubMed Web of Science ®Google Scholar
• Maccario R, Podesta M, Moretta A, Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype. Haematologica 2005;90:516-25
   PubMed Web of Science ®Google Scholar
• Corcione A, Benvenuto F, Ferretti E, Human mesenchymal stem cells modulate B-cell functions. Blood 2006;107:367-72
   PubMed Web of Science ®Google Scholar
• Devine SM, Cobbs C, Jennings M, Mesenchymal stem cells distribute to a wide range of tissues following systemic infusion into nonhuman primates. Blood 2003;101:2999-3001
   PubMed Web of Science ®Google Scholar
• Gao J, Dennis JE, Muzic RF, The dynamic in vivo distribution of bone marrow-derived mesenchymal stem cells after infusion. Cells Tissues Organs 2001;169:12-20
   PubMed Web of Science ®Google Scholar
• Liechty KW, MacKenzie TC, Shaaban AF, Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 2000;6:1282-6
   PubMed Web of Science ®Google Scholar
• Wynn RF, Hart CA, Corradi-Perini C, A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood 2004;104:2643-5
   PubMed Web of Science ®Google Scholar
• Brooke G, Tong H, Levesque JP, Atkinson K. Molecular trafficking mechanisms of multipotent mesenchymal stem cells derived from human bone marrow and placenta. Stem Cells Dev 2008;17:929-40
   PubMed Web of Science ®Google Scholar
• Lee RH, Seo MJ, Reger RL, Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/scid mice. Proc Natl Acad Sci USA 2006;103:17438-43
   PubMed Web of Science ®Google Scholar
• Lee JW, Fang X, Gupta N, Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci USA 2009;106:16357-62
   PubMed Web of Science ®Google Scholar
• Yamada Y, Ueda M, Naiki T, Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: tissue-engineered bone regeneration. Tissue Eng 2004;10:955-64
   PubMedGoogle Scholar
• Koc ON, Day J, Nieder M, Allogeneic mesenchymal stem cell infusion for treatment of metachromatic leukodystrophy (MLD) and Hurler syndrome (MPS-IH). Bone Marrow Transplant 2002;30:215-22
   PubMed Web of Science ®Google Scholar
• Studeny M, Marini FC, Champlin RE, Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Res 2002;62:3603-8
   PubMed Web of Science ®Google Scholar
• Zhou K, Zhang H, Jin O, Transplantation of human bone marrow mesenchymal stem cell ameliorates the autoimmune pathogenesis in MRL/lpr mice. Cell Mol Immunol 2008;5:417-24
   PubMed Web of Science ®Google Scholar
• Nauta AJ, Westerhuis G, Kruisselbrink AB, Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006;108:2114-20
   PubMed Web of Science ®Google Scholar
• Spees JL, Gregory CA, Singh H, Internalized antigens must be removed to prepare hypoimmunogenic mesenchymal stem cells for cell and gene therapy. Mol Ther 2004;9:747-56
   PubMed Web of Science ®Google Scholar
• Doucet C, Ernou I, Zhang Y, Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applications. J Cell Physiol 2005;205:228-36
   PubMed Web of Science ®Google Scholar