Alphavirus vectors: development and potential therapeutic applications

Bibliography

• SCHLESINGER S, SCHLESINGER MJ: Togaviridae:theviruses and their replication. In: Togaviridae:the viruses and their replication. Fields BN, Knipe DM, Howley PMS (Eds.). Lippincott-Raven Philadelphia, Country (1996): 825–841
   Google Scholar
• STRAUSS JH, STRAUSS EG: The alphaviruses: geneexpression, replication and evolution. Micro biol. Rev. (1994) 58:491–562.
   PubMedGoogle Scholar
• WANG K-S, SCHMALJOHN AL, KUHN RJ, STRAUSS JH: Antiidiotypic antibodies as probes for the Sindbis virus receptor. Virology (1991) 181:694–702.
   PubMed Web of Science ®Google Scholar
• WANG K-S, KUHN RJ, STRAUSS EG, OU S, STRAUSS JH: High-affinitylaminin receptor is a receptor for Sindbis virus in mammalian cells. J. Virol. (1992) 66:4992–5001.
   PubMed Web of Science ®Google Scholar
• BYRNES AP, GRIFFIN DE: Binding of Sindbis virus to cell surface heparan sulfate. J. Virol. (1998) 72:7349–7356.
   PubMed Web of Science ®Google Scholar
• KLIMSTRA WB, RYMAN KD, JOHNSTON RE: Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor. J. Virol. (1998) 72:7357–7366.
   PubMed Web of Science ®Google Scholar
• OHNO K, SAWAI K, IIJIMA Y, LEVIN B, MERUELO D:Cell-specific targeting of Sindbis virus vectors displaying IgG-binding domains of protein A. Nat. Biotechnol. (1997) 15:763–767.
   PubMed Web of Science ®Google Scholar
• LEMM JA, RUMENAPF T, STRAUSS EG, STRAUSS JH, RICE CM: Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus and plus-strand RNA synthesis. EMBOJ. (1994) 13:2925–2934.
   PubMed Web of Science ®Google Scholar
• LEMM JA, BERGQVIST A, READ CM, RICE CM: Template-dependent initiation of Sindbis virus RNA replication in vitro. J. Virol. (1998) 72:6546–6553.
   PubMed Web of Science ®Google Scholar
• LEVIS R, SCHLESINGER S, HUANG HV: Promoter for Sindbis virus RNA-dependent subgenomic RNA transcription. J. Virol. (1990) 64:1726–1733.
   PubMed Web of Science ®Google Scholar
• RAJU R, HUANG HV: Analysis of Sindbis virus promoterrecognition in vivo, using novel vectors with two subgenomic mRNA promoters. J. Virol. (1991) 65:2501–2510.
   PubMed Web of Science ®Google Scholar
• WEISS B, NITSCHKO H, GHATTAS I, WRIGHT R, SCHLES-INGER S: Evidence for specificity in the encapsidation of Sindbis virus RNAs. J. Virol. (1989) 63:5310–5318.
   PubMed Web of Science ®Google Scholar
• FROLOVA E, FROLOV I, SCHLESINGER S: Packaging signals in alphaviruses. J. Virol. (1997) 71:248–258.
   PubMed Web of Science ®Google Scholar
• FROLOV I, SCHLESINGER S: Comparison of the effects of Sindbis virus and Sindbis virus replicons on host cell protein synthesis and cytopathogenicity in BHK cells. J. Virol. (1994) 68:1721–1727.
   PubMed Web of Science ®Google Scholar
• LEVINE B, HUANG Q, ISAACS JT, REED JC, GRIFFIN DE, HARDWICK JM: Conversion of lytic to persistent alphavirus infection by the bc1-2 cellular oncogene. Nature (1993) 361:739–742.
   PubMed Web of Science ®Google Scholar
• SCALLAN MF, ALLSOPP TE, FAZAKERLEY JK: Bc1-2 actsearly to restrict Semliki Forest virus replication and delays virus-induced programmed cell death. J. Virol. (1997) 71:1583–1590.
   PubMed Web of Science ®Google Scholar
• XIONG C, LEVIS R, SHEN P, SCHLESINGER S, RICE CM,HUANG HV: Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science (1989) 243:1188–1191.
   PubMed Web of Science ®Google Scholar
• LILJESTROM P, GAROFF H: A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Biol. Technology (1991) 9:1356–1361.
   PubMed Web of Science ®Google Scholar
• HERWEIJER H, LATENDRESSE JS, WILLIAMS P et al.: A plasmid-based self-amplifying Sindbis virus vector. Hum. Gene Ther. (1995) 6:1161–1167.
   PubMed Web of Science ®Google Scholar
• DUBENSKY TWJ, DRIVER DA, POLO JM et al.: Sindbisvirus DNA-based expression vectors: utility for in vitro and in vivo gene transfer. J. Virol. (1996) 70:508–519.
   PubMed Web of Science ®Google Scholar
• BREDENBEEK PJ, FROLOV I, RICE CM, SCHLESINGER S:Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs. J. Virol. (1993) 67:6439–6446.
   PubMed Web of Science ®Google Scholar
• BERGLUND P, SJOBERG M, GAROFF H, ATKINS GJ, SHEAHAN BJ, LILJESTROM P: Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Biotechnology (1993) 11:916–920.
   PubMed Web of Science ®Google Scholar
• DUBUISSON J, RICE CM: Sindbis virus attachment: isolation and characterization of mutants with impaired binding to vertebrate cells. J. Virol. (1993) 67:3363–3374.
   PubMed Web of Science ®Google Scholar
• FROLOV I, FROLOVA E, SCHLESINGER S: Sindbis virusreplicons and Sindbis virus: assembly of chimeras and of particles deficient in virus RNA. J. Virol. (1997) 71:2819–2829.
   PubMed Web of Science ®Google Scholar
• PUSHKO P, PARKER M, LUDWIG GV, DAVIS NL, JOHNSTON RE, SMITH JF: Replicon-helper systems from attenuated Venezuelan equine encephalitis virus: expression of heterologous genes in vitro and immunization against heterologous pathogens in vivo. Virology (1997) 239:389–401.
   PubMed Web of Science ®Google Scholar
• SMERDOU C, LILJESTROM P: Two-helper RNA system forproduction of recombinant Semliki Forest virus particles. J. Virol. (1999) 73:1092–1098.
   PubMed Web of Science ®Google Scholar
• POLO JM, BELLI BA, DRIVER DA et al.: STable alphaviruspackaging cell lines for Sindbis virus and Semliki Forest virus-derived vectors. Proc. Natl. Acad. Sci. USA (1999) 96:4598–4603.
   PubMed Web of Science ®Google Scholar
• HAHN CS, HAHN YS, BRACIALE TJ, RICE CM: InfectiousSindbis virus transient expression vectors for studying antigen processing and presentation. Proc. Natl. Acad. Sci. USA (1992) 89:2679–2683.
   PubMed Web of Science ®Google Scholar
• OLIVO PD, FROLOV I, SCHLESINGER S: A cell line thatexpresses a reporter gene in response to infection by Sindbis virus: a prototype for detection of positive strand RNA viruses. Virology (1994) 198:381–384.
   PubMed Web of Science ®Google Scholar
• AGAPOV EV, FROLOV I, LINDENBACH BD, PRAGAI BM,SCHLESINGER S, RICE CM: Noncytopathic Sindbis virus RNA vectors for heterologous gene expression. Proc. Natl. Acad. Sci. USA (1998) 95:12989–12994.
   PubMed Web of Science ®Google Scholar
• LEVIS R, HUANG H, SCHLESINGER S: Engineered defective interfering RNAs of Sindbis virus express bacterial chloramphenicol acetyltransferase in avian cells. Proc. Natl. Acad. Sci. USA (1987) 84:4811–4815.
   PubMed Web of Science ®Google Scholar
• LONDON SD, SCHMALJOHN AL, DALRYMPLE JM, RICECM: Infectious enveloped RNA virus antigenic chimeras. Proc. Natl. Acad. Sci. USA (1992) 89:207–211.
   PubMed Web of Science ®Google Scholar
• WEISS B, ROSENTHAL R, SCHLESINGER S: Establishment and maintenance of persistent infection by Sindbis virus in BHK cells. J. Virol. (1980) 33:463–474.
   PubMed Web of Science ®Google Scholar
• DRYGA SA, DRYGA OA, SCHLESINGER S: Identification of mutations in a Sindbis virus variant able to establish persistent infection in BHK cells: the importance of a mutation in the nsP2 gene. Virology (1997) 228:74–83.
   PubMed Web of Science ®Google Scholar
• FROLOV I, AGAPOV E, HOFFMAN TA, Jr. et al.: Selection of RNA replicons capable of persistent noncytopathic replication in mammalian cells. J. Virol. (1999) 73:3854–3865.
   Google Scholar
• PERRI S, DRIVER DA, GARDNER JP etai.: Replicon vectorsderived from Sindbis virus and Semliki forest virus that establish persistent replication in host cells. J. Virol. (2000) 74:9802–9807.
   Google Scholar
• UBOL S, TUCKER PC, GRIFFIN DE, HARDWICK JM: Neurovirulent strains of Alphavirus induce apoptosis in bc1-2- expressing cells: role of a single amino acid change in the E2 glycoprotein. Proc. Natl. Acad. Sci. USA (1994) 91:5202–5206.
   PubMed Web of Science ®Google Scholar
• LANDIS H, SIMON-JODICKE A, KLOTI A et al.: Human MxA protein confers resistance to Semliki Forest virus and inhibits the amplification of a Semliki Forest virus-based replicon in the absence of viral structural proteins. J. Virol. (1998) 72:1516–1522.
   PubMed Web of Science ®Google Scholar
• SCHLESINGER S, DUBENSKY TW: Alphavirus vectors for gene expression and vaccines. Curr. Opin. Biotechnol. (1999) 10:434–439.
   PubMed Web of Science ®Google Scholar
• LUNDSTROM K: Alphaviruses as tools in neurobiologyand gene therapy. J. Recept. Signal Transduct. Res. (1999) 19:673–686.
   PubMed Web of Science ®Google Scholar
• LUNDSTROM K: Alphaviruses as expression vectors.Curr. Opin. Biotechnol. (1997) 8:578–582.
   PubMed Web of Science ®Google Scholar
• GAROFF H, LI KJ: Recent advances in gene expression using alphavirus vectors. Curr. Opin. Biotechnol. (1998) 9:464–469.
   PubMed Web of Science ®Google Scholar
• FROLOV I, SCHLESINGER S: Translation of Sindbis virus mRNA: effects of sequences downstream of the initiating codon. J. Virol. (1994) 68:8111–8117.
   PubMed Web of Science ®Google Scholar
• FROLOV I, SCHLESINGER S: Translation of Sindbis virus mRNA: analysis of sequences downstream of the initiating AUG codon that enhance translation. J. Virol. (1996) 70:1182–1190.
   PubMed Web of Science ®Google Scholar
• SJOBERG EM, SUOMALAINEN M, GAROFF H: A signifi-cantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene. Biotechnology(1994) 12:1127–1131.
   PubMedGoogle Scholar
• SJOBERG E M, GAROFF H: The translation-enhancing region of the Semliki Forest virus subgenome is only functional in the virus-infected cell. J. Gen. Virol. (1996) 77:1323–1327.
   PubMed Web of Science ®Google Scholar
• STRONG TV, HAMPTON TA, LOURO I, BILBAO G, CONRYRM, CURIEL DT: Incorporation of beta-globin untrans-lated regions into a Sindbis virus vector for augmenta-tion of heterologous mRNA expression. Gene Ther. (1997) 4:624–627.
   PubMed Web of Science ®Google Scholar
• BOORSMA M, NIEBA L, KOLLER D, BACHMANN MF, BAILEY JE, RENNER WA: A temperature-regulated replicon-based DNA expression system. Nature Biotechnol. (2000) 18:429–432.
   PubMed Web of Science ®Google Scholar
• •• Design of a stable cell line in which a Sindbis virus repliconis induced by temperature and its use for producing protein.
   Google Scholar
• JOHNSON BW, OLSON KE, ALLEN-MIURA T et al.: Inhibition of luciferase expression in transgenic Aedes aegypti mosquitoes by Sindbis virus expression of antisense luciferase RNA. Proc. Natl. Acad. Sci. U S A (1999) 96:13399–13403.
   PubMed Web of Science ®Google Scholar
• • Demonstrates the potential of using Sindbis vectors to synthesise antisense RNAs. In this example the antisense RNA was able to inhibit expression of a gene inserted into the mosquito genome.
   Google Scholar
• BLAIR CD, ADELMAN ZN, OLSON KE: Molecular strate-gies for interrupting arthropod-borne virus transmis-sion by mosquitoes. Clin. Microbiol. Rev. (2000) 13:651–661.
   PubMed Web of Science ®Google Scholar
• OLSON KE, HIGGS S, GAINESPJ et al.: Genetically engineered resistance to dengue-2 virus transmission in mosquitoes. Science (1996) 272:884–886.
   PubMed Web of Science ®Google Scholar
• HIGGS S, RAYNER JO, OLSON KE, DAVIS BS, BEATY BJ, BLAIR CD: Engineered resistance in Aedes aegypti to a West African and a South American strain of yellow fever virus. Am. J. Trop. Med. Hyg. (1998) 58:663–670.
   PubMed Web of Science ®Google Scholar
• LEWIS DL, DECAMILLIS MA, BRUNETTI CR et al.: Ectopic gene expression and homeotic transformations in arthropods using recombinant Sindbis viruses. Cum Biol. (1999) 9:1279–1287.
   PubMed Web of Science ®Google Scholar
• •• Investigation of homeotic gene function in butterflies andbeetle embryos using Sindbis virus vectors.
   Google Scholar
• EHRENGRUBER MU, LUNDSTROM K, SCHWEITZER C, HEUSS C, SCHLESINGER S, GATIWILER BH: Recombinant Semliki Forest virus and Sindbis virus efficiently infect neurons in hippocampal slice cultures. Proc. Natl. Acad. Sci. USA (1999) 96:7041–7046.
   PubMed Web of Science ®Google Scholar
• MALETIC-SAVATIC M, MALINOW R, SVOBODA K: Rapiddendritic morphogenesis in CA1 hippocampal dendrites induced by synaptic activity. Science (1999) 283: 1923-1927.
   Google Scholar
• SHI SH, HAYASHI Y, PETRALIA RS et al.: Rapid spinedelivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science (1999) 284:1811–1816.
   PubMed Web of Science ®Google Scholar
• OSTEN P, KHATRI L, PEREZ JL et al.: Mutagenesis revealsa role for ABP/GRIP binding to G1uR2 in synaptic surface accumulation of the AMPA receptor. Neuron (2000) 27:313–325.
   PubMed Web of Science ®Google Scholar
• DAVIS NL, BROWN KW, JOHNSTON RE: A viral vaccinevector that expresses foreign genes in lymph nodes and protects against mucosal challenge. J. Virol. (1996) 70:3781–3787.
   PubMed Web of Science ®Google Scholar
• MACDONALD GH, JOHNSTON RE: Role of dendritic cell targeting in Venezuelan equine encephalitis virus pathogenesis. J. Virol. (2000) 74:914–922.
   PubMed Web of Science ®Google Scholar
• • Shows a correlation between virulence of VEE virus and its ability to target to murine dendritic cells.
   Google Scholar
• GARDNER JP, FROLOV I, PERRI S et al.: Infection of human dendritic cells by a sindbis virus replicon vector is determined by a single amino acid substitu-tion in the E2 glycoprotein. J. Virol. (2000) 74:11849–11857.
   PubMed Web of Science ®Google Scholar
• • Identifies mutations in the Sindbis virus E2 glycoprotein that greatly enhance the ability of the replicon particles to infect human dendritic cells.
   Google Scholar
• BERGLUND P, SMERDOU C, FLEETON MN, TUBULEKAS I,LILJESTROM P: Enhancing immune responses using suicidal DNA vaccines. Nat. Biotechnol. (1998) 16:562–565.
   PubMed Web of Science ®Google Scholar
• HARIHARAN MJ, DRIVER DA, TOWNSEND K et al.: DNAimmunization against herpes simplex virus: enhanced efficacy using a Sindbis virus-based vector. J. Virol. (1998) 72:950–958.
   PubMed Web of Science ®Google Scholar
• CHARLES PC, BROWN KW, DAVIS NL, HART MK, JOHNSTON RE: Mucosal immunity induced by parenteral immunization with a live attenuated Venezuelan equine encephalitis virus vaccine candidate. Virology (1997) 228:153–160.
   PubMed Web of Science ®Google Scholar
• COLOMBAGE G, HALL R, PAVY M, LOBIGS M: DNA-basedand alphavirus-vectored immunisation with prM and E proteins elicits long-lived and protective immunity against the flavivirus, Murray Valley encephalitis virus. Virology (1998) 250:151–163.
   PubMed Web of Science ®Google Scholar
• TSUJI M, BERGMANN CC, TAKITA-SONODA Y et al.: Recombinant Sindbis viruses expressing a cytotoxic T-lymphocyte epitope of a malaria parasite or of influenza virus elicit protection against the corresponding pathogen in mice. J. Virol. (1998) 72:6907–6910.
   PubMed Web of Science ®Google Scholar
• HEVEY M, NEGLEY D, PUSHKO P, SMITH J, SCHMALJOHNA: Marburg virus vaccines based upon alphavirus replicons protect guinea pigs and nonhuman primates. Virology (1998) 251:28–37.
   PubMed Web of Science ®Google Scholar
• BERGLUND P, QUESADA-ROLANDER M, PUTKONEN P, BIBERFELD G, THORSTENSSON R, LILJESTROM P: Outcome of immunization of cynomolgus monkeys with recombinant Semliki Forest virus encoding human immunodeficiency virus Type 1 envelope protein and challenge with a high dose of SHIV-4 virus. AIDS Res. Hum. Retroviruses (1997) 13:1487–1495.
   PubMed Web of Science ®Google Scholar
• MOSSMAN SP, BEX F, BERGLUND P et al.: Protection against lethal simian immunodeficiency virus SIVsmniPB0.4 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J. Virol. (1996) 70:1953–1960.
   Google Scholar
• DAVIS NL, CALEY IJ, BROWN KW et al.: Vaccination of macaques against pathogenic simian immunodefi-ciency virus with Venezuelan equine encephalitis virus replicon particles. J. Virol. (2000) 74:371–378.
   PubMed Web of Science ®Google Scholar
• IVANOVA L, SCHLESINGER S, OLIVO PD: Regulated expression of a Sindbis virus replicon by herpesvirus promoters. J. Virol. (1999) 73:1998–2005.
   PubMed Web of Science ®Google Scholar
• • Induction of a wild type Sindbis virus replicon and a prototype assay for detection of herpesviruses.
   Google Scholar
• OLIVO PD, COLLINS PL, PEEPLES ME, SCHLESINGER S: Detection and quantitation of human respiratory syncytial virus (RSV) using minigenome cDNA and a Sindbis virus replicon: a prototype assay for negative-strand RNA viruses. Virology (1998) 251:198–205.
   PubMed Web of Science ®Google Scholar
• • Use of the non-cytopathic Sindbis virus replicon in design of a prototype assay for negative-strand RNA viruses.
   Google Scholar
• KOLLER D, RUEDL C, LOETSCHER M et al.: A high-throughput functional expression cloning system for mammalian cells. (2001) Submitted.
   Google Scholar
• YING H, ZAKS TZ, WANG RF et al.: Cancer therapy using a self-replicating RNA vaccine. Nat. Med. (1999) 5:823–827.
   PubMed Web of Science ®Google Scholar
• LEITNER WW, YING H, DRIVER DA, DUBENSKY TW, RESTIFO NP: Enhancement of tumor-specific immune response with plasmid DNA replicon vectors. Cancer Res. (2000) 60:51–55.
   PubMed Web of Science ®Google Scholar
• IIJIMA Y, OHNO K, IKEDA H, SAWAI K, LEVIN B, MERUELO D: Cell-specific targeting of a thymidine kinase/ganciclovir gene therapy system using a recombinant Sindbis virus vector. Int. J. Cancer (1999) 80:110–118.
   PubMed Web of Science ®Google Scholar
• WAHLFORS JJ, ZULLO SA, LOIMAS S, NELSON DM, MORGAN RA: Evaluation of recombinant alphaviruses as vectors in gene therapy. Gene Ther. (2000) 7:472–480.
   PubMed Web of Science ®Google Scholar
• EHRENGRUBER M, HENNOU S, BUELER H, NAIM H, LUNDSTROM K: Gene transfer into neurons from hippocampal slices by recombinant Semliki Forest virus, adenovirus, adeno-associated virus and measles virus. (2001) Submitted.
   Google Scholar
• DICIOMMO DP, BREMNER R: Rapid, high level protein production using DNA-based Semliki Forest virus vectors. J. Biol. Chem. (1998) 273:18060–18066.
   PubMed Web of Science ®Google Scholar
• CONNETT H: News. Nature Medicine (2000) 1199–1200.
   PubMedGoogle Scholar
• LUNDSTROM K, BLASEY H, HOVIUS R, VOGEL H, BERNARD A: The Semliki Forest virus system: receptor expression and scale-up. Genetic Engineer and Biotech-nologist (1997) 17:101–106.
   Google Scholar