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Review

In utero stem cell transplantation: two steps forward but one step back?

Pages 205-212 | Published online: 23 Feb 2005

Bibliography

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  • Reinforces the original 'experiments of nature' by showing that in utero tolerance is not uncommon. WEST L, MORRIS JPJ, WOOD KJ: Fetal liver haemato-poietic cells and tolerance to organ allografts. Lancet (1994) 343:148–149.
  • ANDERSON EM, JONES DRE, LIU DTY, EVANS AA:Gestational age and cell viability determine the effect of frozen storage on human fetal hematopoietic progenitor cell preparations. Fetal. Diagn. Ther. (1996) 11:427–432.
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  • • Investigations which suggest immune function in the fetal liver.
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  • • An alternative view of the significance of immune cells in the fetus.
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  • •• A thorough study of the mechanisms by which tolerance canbe achieved in utero.
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  • •• A good workup of the consequences of an IUT which hasapparently failed.
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  • • An important paper because the transplant recipients did not have a haematological defect.
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  • •• A seminal paper outlining the differences between stemcells from various sources.
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  • • A useful reference to the functional differences between stem cells.
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  • •• A milestone in our understanding of stem cell function andpotential.
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  • • A good overview of the state of gene therapy at the beginning of the new millennium.
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  • •• A seminal paper with the first convincing series of genetherapy cases. Future developments from this group are eagerly awaited.
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  • • A good overview.
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