392
Views
34
CrossRef citations to date
0
Altmetric
Reviews

Mesenchymal stem cell therapy for chronic renal failure

, &
Pages 1217-1226 | Published online: 13 Jul 2010

Bibliography

  • Levey AS, Andreoli SP, DuBose T, Chronic kidney disease: common, harmful, and treatable – World Kidney Day 2007. J Am Soc Nephrol 2007;18:374-8
  • Danovitch GM, Cohen DJ, Weir MR, Current status of kidney and pancreas transplantation in the United States, 1994-2003. Am J Transplant 2005;5:904-15
  • Starzl TE, Marchioro TL, Peters GN, Renal heterotransplantation from baboon to man: experience with 6 cases. Transplantation 1964;2:752-76
  • Zaidi A, Schmoeckel M, Bhatti F, Life-supporting pig-to-primate renal xenotransplantation using genetically modified donors. Transplantation 1998;65:1584-90
  • Cascalho M, Ogle BM, Platt JL. Xenotransplantation and the future of renal replacement. J Am Soc Nephrol 2004;15:1106-12
  • Hammerman MR. Cellular therapies for kidney failure. Expert Opin Biol Ther 2006;6:87-97
  • da Silva Meirelles L, Chagastelles PC, Nardi NB. Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 2006;119:2204-13
  • Picinich SC, Mishra PJ, Glod J, The therapeutic potential of mesenchymal stem cells. Cell- and tissue-based therapy. Expert Opin Biol Ther 2007;7:965-73
  • Morigi M, Imberti B, Zoja C, Mesenchymal stem cells are renotropic, helping to repair the kidney and improve function in acute renal failure. J Am Soc Nephrol 2004;15:1794-804
  • Harris RC, Neilson EG. Toward a unified theory of renal progression. Annu Rev Med 2006;57:365-80
  • Ninichuk V, Gross O, Segerer S, Multipotent mesenchymal stem cells reduce interstitial fibrosis but do not delay progression of chronic kidney disease in collagen4A3-deficient mice. Kidney Int 2006;70:121-9
  • Kunter U, Rong S, Boor P, Mesenchymal stem cells prevent progressive experimental renal failure but maldifferentiate into glomerular adipocytes. J Am Soc Nephrol 2007;18:1754-64
  • Kunter U, Rong S, Djuric Z, Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis. J Am Soc Nephrol 2006;17:2202-12
  • Choi S, Park M, Kim J, The role of mesenchymal stem cells in the functional improvement of chronic renal failure. Stem Cells Dev 2009;18:521-9
  • Eliopoulos N, Gagnon RF, Francois M, Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure. J Am Soc Nephrol 2006;17:1576-84
  • Prodromidi EI, Poulsom R, Jeffery R, Bone marrow-derived cells contribute to podocyte regeneration and amelioration of renal disease in a mouse model of Alport syndrome. Stem Cells 2006;24:2448-55
  • Yokoo T, Ohashi T, Shen JS, Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues. Proc Natl Acad Sci USA 2005;102:3296-300
  • Cavaglieri RC, Martini D, Sogayar MC, Mesenchymal stem cells delivered at the subcapsule of the kidney ameliorate renal disease in the rat remnant kidney model. Transplant Proc 2009;41:947-51
  • Semedo P, Correa-Costa M, Antonio Cenedeze M, Mesenchymal stem cells attenuate renal fibrosis through immune modulation and remodeling properties in a rat remnant kidney model. Stem Cells 2009;27:3063-73
  • Caldas HC, Fernandes IM, Gerbi F, Effect of whole bone marrow cell infusion in the progression of experimental chronic renal failure. Transplant Proc 2008;40:853-5
  • McTaggart SJ, Atkinson K. Mesenchymal stem cells: immunobiology and therapeutic potential in kidney disease. Nephrology 2007;12:44-52
  • Wexler SA, Donaldson C, Denning-Kendall P, Adult bone marrow is a rich source of human mesenchymal ‘stem’ cells but umbilical cord and mobilized adult blood are not. Br J Haematol 2003;121:368-74
  • Ulloa-Montoya F, Verfaillie CM, Hu WS. Culture systems for pluripotent stem cells. J Biosci Bioeng 2005;100:12-27
  • Meirelles Lda S, Nardi NB. Murine marrow-derived mesenchymal stem cell: isolation, in vitro expansion, and characterization. Br J Haematol 2003;123:702-11
  • Challen GA, Bertoncello I, Deane JA, Kidney side population reveals multilineage potential and renal functional capacity but also cellular heterogeneity. J Am Soc Nephrol 2006;17:1896-912
  • Hishikawa K, Marumo T, Miura S, Musculin/MyoR is expressed in kidney side population cells and can regulate their function. J Cell Biol 2005;169:921-8
  • Sagrinati C, Netti GS, Mazzinghi B, Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. J Am Soc Nephrol 2006;17:2443-56
  • Bruno S, Bussolati B, Grange C, Isolation and characterization of resident mesenchymal stem cells in human glomeruli. Stem Cells Dev 2009;18:867-80
  • Plotkin MD, Goligorsky MS. Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin-producing fibroblasts. Am J Physiol Renal Physiol 2006;291:F902-12
  • Chen J, Park HC, Addabbo F, Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair. Kidney Int 2008;74:879-89
  • Majumdar MK, Keane-Moore M, Buyaner D, Characterization and functionality of cell surface molecules on human mesenchymal stem cells. J Biomed Sci 2003;10:228-41
  • Zhang W, Ge W, Li C, Effects of mesenchymal stem cells on differentiation, maturation, and function of human monocyte-derived dendritic cells. Stem Cells Dev 2004;13:263-71
  • Krampera M, Glennie S, Dyson J, Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003;101:3722-9
  • Plumas J, Chaperot L, Richard MJ, Mesenchymal stem cells induce apoptosis of activated T cells. Leukemia 2005;19:1597-604
  • Huang Y, Johnston P, Zhang B, Kidney-derived stromal cells modulate dendritic and T cell responses. J Am Soc Nephrol 2009;20:831-41
  • Ringden O, Uzunel M, Sundberg B, Tissue repair using allogeneic mesenchymal stem cells for hemorrhagic cystitis, pneumomediastinum and perforated colon. Leukemia 2007;21:2271-6
  • Dryden GW. Overview of stem cell therapy for Crohn's disease. Expert Opin Biol Ther 2009;9:841-7
  • Garcia-Olmo D, Herreros D, Pascual M, Treatment of enterocutaneous fistula in Crohn's Disease with adipose-derived stem cells: a comparison of protocols with and without cell expansion. Int J Colorectal Dis 2009;24:27-30
  • Garcia-Olmo D, Garcia-Arranz M, Herreros D. Expanded adipose-derived stem cells for the treatment of complex perianal fistula including Crohn's disease. Expert Opin Biol Ther 2008;8:1417-23
  • Le Blanc K, Ringden O. Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2005;11:321-34
  • Ito T, Suzuki A, Imai E, Bone marrow is a reservoir of repopulating mesangial cells during glomerular remodeling. J Am Soc Nephrol 2001;12:2625-35
  • Poulsom R, Forbes SJ, Hodivala-Dilke K, Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol 2001;195:229-35
  • Duffield JS, Park KM, Hsiao LL, Restoration of tubular epithelial cells during repair of the postischemic kidney occurs independently of bone marrow-derived stem cells. J Clin Invest 2005;115:1743-55
  • Duffield JS, Bonventre JV. Kidney tubular epithelium is restored without replacement with bone marrow-derived cells during repair after ischemic injury. Kidney Int 2005;68:1956-61
  • Imasawa T, Utsunomiya Y, Kawamura T, The potential of bone marrow-derived cells to differentiate to glomerular mesangial cells. J Am Soc Nephrol 2001;12:1401-9
  • Oliver JA, Maarouf O, Cheema FH, The renal papilla is a niche for adult kidney stem cells. J Clin Invest 2004;114:795-804
  • Shi S, Gronthos S. Perivascular niche of postnatal mesenchymal stem cells in human bone marrow and dental pulp. J Bone Miner Res 2003;18:696-704
  • Farrington-Rock C, Crofts NJ, Doherty MJ, Chondrogenic and adipogenic potential of microvascular pericytes. Circulation 2004;110:2226-32
  • Fine LG, Orphanides C, Norman JT. Progressive renal disease: the chronic hypoxia hypothesis. Kidney Int Suppl 1998;65:S74-8
  • Norman JT, Clark IM, Garcia PL. Hypoxia promotes fibrogenesis in human renal fibroblasts. Kidney Int 2000;58:2351-66
  • Fine LG, Bandyopadhay D, Norman JT. Is there a common mechanism for the progression of different types of renal diseases other than proteinuria? Towards the unifying theme of chronic hypoxia. Kidney Int Suppl 2000;75:S22-6
  • Taal MW, Chertow GM, Rennke HG, Mechanisms underlying renoprotection during renin-angiotensin system blockade. Am J Physiol Renal Physiol 2001;280:F343-55
  • Taal MW, Omer SA, Nadim MK, Cellular and molecular mediators in common pathway mechanisms of chronic renal disease progression. Curr Opin Nephrol Hypertens 2000;9:323-31
  • Iwano M, Plieth D, Danoff TM, Evidence that fibroblasts derive from epithelium during tissue fibrosis. J Clin Invest 2002;110:341-50
  • Yamashita S, Maeshima A, Nojima Y. Involvement of renal progenitor tubular cells in epithelial-to-mesenchymal transition in fibrotic rat kidneys. J Am Soc Nephrol 2005;16:2044-51
  • Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med 2004;82:175-81
  • Zeisberg M, Bottiglio C, Kumar N, Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol 2003;285:F1060-7
  • Strutz F, Zeisberg M, Ziyadeh FN, Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int 2002;61:1714-28
  • Bottinger EP, Bitzer M. TGF-beta signaling in renal disease. J Am Soc Nephrol 2002;13:2600-10
  • Schiffer M, Bitzer M, Roberts IS, Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest 2001;108:807-16
  • Kang DH, Kanellis J, Hugo C, Role of the microvascular endothelium in progressive renal disease. J Am Soc Nephrol 2002;13:806-16
  • Kang DH, Anderson S, Kim YG, Impaired angiogenesis in the aging kidney: vascular endothelial growth factor and thrombospondin-1 in renal disease. Am J Kidney Dis 2001;37:601-11
  • Kang DH, Hughes J, Mazzali M, Impaired angiogenesis in the remnant kidney model: II. Vascular endothelial growth factor administration reduces renal fibrosis and stabilizes renal function. J Am Soc Nephrol 2001;12:1448-57
  • Grone HJ, Simon M, Grone EF. Expression of vascular endothelial growth factor in renal vascular disease and renal allografts. J Pathol 1995;177:259-67
  • Choi YJ, Chakraborty S, Nguyen V, Peritubular capillary loss is associated with chronic tubulointerstitial injury in human kidney: altered expression of vascular endothelial growth factor. Hum Pathol 2000;31:1491-7
  • Shulman K, Rosen S, Tognazzi K, Expression of vascular permeability factor (VPF/VEGF) is altered in many glomerular diseases. J Am Soc Nephrol 1996;7:661-6
  • Yokoo T, Fukui A, Matsumoto K, Kidney regeneration by xeno-embryonic nephrogenesis. Med Mol Morphol 2008;41:5-13
  • Steenhard BM, Isom KS, Cazcarro P, Integration of embryonic stem cells in metanephric kidney organ culture. J Am Soc Nephrol 2005;16:1623-31
  • Kobayashi T, Tanaka H, Kuwana H, Wnt4-transformed mouse embryonic stem cells differentiate into renal tubular cells. Biochem Biophys Res Commun 2005;336:585-95
  • Yamamoto M, Cui L, Johkura K, Branching ducts similar to mesonephric ducts or ureteric buds in teratomas originating from mouse embryonic stem cells. Am J Physiol Renal Physiol 2006;290:F52-60
  • Lanza RP, Chung HY, Yoo JJ, Generation of histocompatible tissues using nuclear transplantation. Nat Biotechnol 2002;20:689-96
  • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76
  • Takahashi K, Tanabe K, Ohnuki M, Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-72
  • Lin F, Cordes K, Li L, Hematopoietic stem cells contribute to the regeneration of renal tubules after renal ischemia-reperfusion injury in mice. J Am Soc Nephrol 2003;14:1188-99
  • Parikh CR, Coca SG. Acute renal failure in hematopoietic cell transplantation. Kidney Int 2006;69:430-5
  • Togel F, Hu Z, Weiss K, Administered mesenchymal stem cells protect against ischemic acute renal failure through differentiation-independent mechanisms. Am J Physiol Renal Physiol 2005;289:F31-42
  • Togel F, Cohen A, Zhang P, Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev 2009;18:475-85
  • Bi B, Schmitt R, Israilova M, Stromal cells protect against acute tubular injury via an endocrine effect. J Am Soc Nephrol 2007;18:2486-96
  • Bruno S, Grange C, Deregibus MC, Mesenchymal stem cell-derived microvesicles protect against acute tubular injury. J Am Soc Nephrol 2009;20:1053-67
  • Alexandre CS, Volpini RA, Shimizu MH, Lineage-negative bone marrow cells protect against chronic renal failure. Stem Cells 2009;27:682-92
  • Asahara T, Murohara T, Sullivan A, Isolation of putative progenitor endothelial cells for angiogenesis. Science 1997;275:964-7
  • Bahlmann FH, Speer T, Fliser D. Endothelial progenitor cells in chronic kidney disease. Nephrol Dial Transplant 2010;25:341-6
  • Maruyama S, Taguchi A, Iwashima S, Low circulating CD34+ cell count is associated with poor prognosis in chronic hemodialysis patients. Kidney Int 2008;74:1603-9
  • Chan CT, Liu PP, Arab S, Nocturnal hemodialysis improves erythropoietin responsiveness and growth of hematopoietic stem cells. J Am Soc Nephrol 2009;20:665-71
  • Choi JH, Kim KL, Huh W, Decreased number and impaired angiogenic function of endothelial progenitor cells in patients with chronic renal failure. Arterioscler Thromb Vasc Biol 2004;24:1246-52
  • Uchimura H, Marumo T, Takase O, Intrarenal injection of bone marrow-derived angiogenic cells reduces endothelial injury and mesangial cell activation in experimental glomerulonephritis. J Am Soc Nephrol 2005;16:997-1004
  • Min TQ, Zhu CJ, Xiang WX, Improvement in endothelial progenitor cells from peripheral blood by ramipril therapy in patients with stable coronary artery disease. Cardiovasc Drugs Ther 2004;18:203-9
  • Yao EH, Fukuda N, Matsumoto T, Losartan improves the impaired function of endothelial progenitor cells in hypertension via an antioxidant effect. Hypertens Res 2007;30:1119-28
  • Llevadot J, Murasawa S, Kureishi Y, HMG-CoA reductase inhibitor mobilizes bone marrow-derived endothelial progenitor cells. J Clin Invest 2001;108:399-405
  • Humpert PM, Djuric Z, Zeuge U, Insulin stimulates the clonogenic potential of angiogenic endothelial progenitor cells by IGF-1 receptor-dependent signaling. Mol Med 2008;14:301-8
  • Bahlmann FH, De Groot K, Spandau JM, Erythropoietin regulates endothelial progenitor cells. Blood 2004;103:921-6
  • Bahlmann FH, DeGroot K, Duckert T, Endothelial progenitor cell proliferation and differentiation is regulated by erythropoietin. Kidney Int 2003;64:1648-52
  • Bi B, Guo J, Marlier A, Erythropoietin expands a stromal cell population that can mediate renoprotection. Am J Physiol Renal Physiol 2008;295:F1017-22
  • Abrahamson DR, Robert B, Hyink DP, Origins and formation of microvasculature in the developing kidney. Kidney Int Suppl 1998;67:S7-11
  • Dekel B, Burakova T, Arditti FD, Human and porcine early kidney precursors as a new source for transplantation. Nat Med 2003;9:53-60
  • Rogers SA, Lowell JA, Hammerman NA, Transplantation of developing metanephroi into adult rats. Kidney Int 1998;54:27-37
  • Rogers SA, Talcott M, Hammerman MR. Transplantation of pig metanephroi. ASAIO J 2003;49:48-52
  • Dekel B, Reisner Y. Embryonic committed stem cells as a solution to kidney donor shortage. Expert Opin Biol Ther 2004;4:443-54
  • Yokoo T, Fukui A, Ohashi T, Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo. J Am Soc Nephrol 2006;17:1026-34
  • Yokoo T, Kawamura T, Kobayashi E. Kidney organogenesis and regeneration: a new era in the treatment of chronic renal failure? Clin Exp Nephrol 2008;12:326-31
  • Humphreys BD, Bonventre JV. The contribution of adult stem cells to renal repair. Nephrol Ther 2007;3:3-10
  • Yokoo T, Kawamura T, Kobayashi E. Stem cells for kidney repair: useful tool for acute renal failure? Kidney Int 2008;74:847-9
  • Westerweel PE, Hoefer IE, Blankestijn PJ, End-stage renal disease causes an imbalance between endothelial and smooth muscle progenitor cells. Am J Physiol Renal Physiol 2007;292:F1132-40
  • Meyer GP, Wollert KC, Lotz J, Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 2006;113:1287-94
  • Wollert KC, Meyer GP, Lotz J, Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004;364:141-8
  • Katritsis DG, Sotiropoulou PA, Karvouni E, Transcoronary transplantation of autologous mesenchymal stem cells and endothelial progenitors into infarcted human myocardium. Catheter Cardiovasc Interv 2005;65:321-9
  • Bang OY, Lee JS, Lee PH, Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 2005;57:874-82
  • Ohgushi H, Kotobuki N, Funaoka H, Tissue engineered ceramic artificial joint–ex vivo osteogenic differentiation of patient mesenchymal cells on total ankle joints for treatment of osteoarthritis. Biomaterials 2005;26:4654-61
  • Wakitani S, Imoto K, Yamamoto T, Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritis Cartilage 2002;10:199-206
  • Horwitz EM, Prockop DJ, Gordon PL, Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood 2001;97:1227-31

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.