512
Views
6
CrossRef citations to date
0
Altmetric
Reviews

Current insulin analogues in the treatment of diabetes: emphasis on type 2 diabetes

&
Pages 209-221 | Published online: 04 Jan 2012

Bibliography

  • Diabetes Data and Trends. Atlanta, GA: Centers for Disease Control and Prevention. 2009. Available from: http://www.cdc.gov/diabetes/statistics/complications_national.htm [Last accessed 14 December 2011]
  • Annual number (in thousands) of new cases of diagnosed diabetes among adults aged 18 – 79 years, United States, 1980 – 2009. Diabetes Data and Trends. Atlanta, GA: Centers for Disease Control and Prevention. 2009. Available from: http://www.cdc.gov/diabetes/statistics/incidence/fig1.htm [Last accessed 14 December 2011]
  • Ray JA, Valentine WJ, Secnik K, Review of the cost of diabetes complications in Australia, Canada, France, Germany, Italy and Spain. Curr Med Res Opin 2005;12:1617-29
  • American Diabetes Association. Standards of medical care in diabetes—2010. Diabetes Care 2010;33(Suppl 1):S11-61
  • Hoerger TJ, Segel JE, Gregg EW, Saaddine JB. Is glycemic control improving in U.S. adults? Diabetes Care 2008;31:81-6
  • Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004;291:335-42
  • Koro CE, Bowlin SJ, Bourgeois N, Fedder DO. Glycemic control from 1988 to 2000 among U.S. adults with diagnosed type 2 diabetes. Diabetes Care 2004;27:17-20
  • Ismail-Beigi F, Moghissi E, Tiktin M, Individualizing glycemic targets in type 2 diabetes mellitus: implications of recent clinical trials. Ann Intern Med 2011;154:554-49
  • Nathan DM. Finding new treatments for diabetes – how many, how fast... how good? N Engl J Med 2007;356:437-40
  • Nathan DM, Buse JB, Davidson MB, American Diabetes Association; European Association for Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32:193-203
  • Centers for Disease Control and Prevention. National diabetes fact sheet: general information and national estimates on diabetes in the United States, 2005. Department of Health and Human Services, Centers for Disease Control and Prevention; Atlanta: 2005
  • The AMD Annals 2009 Working Group. Longitudinal analysis of quality indicators of diabetes care in Italy (2004 – 2007). Associazione Medici Diabetologi, Rome; 2009. Available from: http://www.infodiabetes.it/files/2009_annali_AMD_eng.pdf
  • Peyrot M, Rubin RR, Lauritzen T, Resistance to insulin therapy among patients and providers: results of the cross-national Diabetes Attitudes, Wishes, and Needs (DAWN) study. Diabetes Care 2005;28:2673-9
  • Karter AJ, Subramanian U, Saha C, Barriers to insulin initiation: the translating research into action for diabetes insulin starts project. Diabetes Care 2010;33:733-5
  • Giugliano D, Esposito K. Clinical inertia as a clinical safeguard. JAMA 2011;305:1591-2
  • Giugliano D, Esposito K. Clinical inertia and uncertainty in medicine. JAMA 2011;206:383-4
  • Hirsch IB. Insulin analogues. N Engl J Med 2005;352:174-83
  • Crasto W, Jarvis J, Khunti K, Davies MJ. New insulins and new insulin regimens: a review of their role in improving glycaemic control in patients with diabetes. Postgrad Med J 2009;85:257-67
  • Evans M, Schumm-Draeger PM, Vora J, King AB. A review of modern insulin analogue pharmacokinetic and pharmacodynamic profiles in type 2 diabetes: improvements and limitations. Diabetes Obes Metab 2011;13:677-84
  • Plank J, Wutte A, Brunner G, A direct comparison of insulin aspart and insulin lispro in patients with type 1 diabetes. Diabetes Care 2002;25:2053-7
  • Gray M, Boland EA, Tamborlane WV. Use of lispro insulin and quality of life in adolescents on intensive therapy. Diabetes Educ 1999;25:934-41
  • Plank J, Siebenhofer A, Berghold A, Systematic review and meta-analysis of short-acting insulin analogues in patients with diabetes mellitus. Arch Intern Med 2005;165:1337-44
  • Hompesch M, Ocheltree SM, Wondmagegnehu ET, Pharmacokinetics and pharmacodynamics of insulin lispro protamine suspension compared with insulin glargine and insulin detemir in type 2 diabetes. Curr Med Res Opin 2009;25:2679-87
  • Smith U, Gale EAM. Does diabetes therapy influence the risk of cancer? Diabetologia 2009;52:1441-5
  • Vigneri R, Squatrito S, Sciacca L. Insulin and its analogs: actions via insulin and IGF receptors. Acta Diabetol 2010;47:271-8
  • Gough SCL, Belda-Iniesta C, Poole C, Insulin Therapy in diabetes and cancer risk: current understanding and implications for future study. Proceedings from a meeting of a European Insulin Safety Consensus Panel, convened and sponsored by Novo Nordisk, held Tuesday October 5, 2010 at The Radisson Edwardian Heathrow Hotel, Hayes, Middlesex, UK. Adv Ther 2011;28(Suppl 5):1-18
  • Werner H, Weinstein D, Yehezkel E, Laron Z. Controversies in the use of insulin analogues. Expert Opin Biol Ther 2011;11:199-209
  • Guidance for industry: diabetes mellitus: developing drugs and therapeutic biologics for treatment and prevention. Food and Drug Administration, Center for Drug Evaluation and Research (CDER); Rcockville, MD: 2008
  • Hauber A, Gale EAM. The market in diabetes. Diabetologia 2006;49:247-52
  • The Dream Trial Investigators. Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomized controlled trial. Lancet 2006;368:1096-105
  • Bolli GB, Di Marchi RD, Park GD, Insulin analogues and their potential in the management of diabetes mellitus. Diabetologia 1999;42:1151-67
  • Plank J, Siebenhofer A, Berghold A, Systemic review and meta-analysis of short-acting insulin analogues in patients with diabetes mellitus. Arch Intern Med 2005;165:1337-44
  • Riddle MC, Rosenstock J, Gerich J; Insulin Glargine 4002 Study Investigators. The treat-to-target trial: randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients. Diabetes Care 2003;26:3080-6
  • Home PD, Fritsche A, Schinzel S, Massi-Benedetti M. Meta-analysis of individual patient data to assess the risk of hypoglycaemia in people with type 2 diabetes using NPH insulin or insulin glargine. Diabetes Obes Metab 2010;12:772-9
  • Lucidi P, Porcellati F, Rossetti P, Pharmacokinetics and pharmacodynamics of therapeutic dose of basal insulins NPH, glargine and detemir after one week of daily administration at bedtime in type 2 diabetes: a randomized, cross-over study. Diabetes Care 2011;34:1312-14
  • Porcellati F, Lucidi P, Rossetti P, Differential effects of adiposity on pharmacodynamics of basal insulins NPH, glargine, and detemir in type 2 diabetes mellitus. Diabetes Care 2011;34:2521-3
  • Swinnen SG, Simon AC, Holleman F, Insulin detemir versus insulin glargine for type 2 diabetes mellitus. Cochrane Database Syst Rev 2011(7):CD006383
  • Fogelfeld L, Dharmalingam M, Robling K, SA, Randomized, treat-to-target trial comparing insulin lispro protamine suspension and insulin detemir in insulin-naive patients with type 2 diabetes. Diabet Med 2010;27:181-8
  • Esposito K, Ciotola M, Maiorino MI, Addition of neutral protamine lispro insulin or insulin glargine to oral type 2 diabetes regimens for patients with suboptimal glycemic control: a randomized trial. Ann Intern Med 2008;149:531-9
  • Strojek K, Shi C, Carey MA, Jacober SJ. Addition of insulin lispro protamine suspension or insulin glargine to oral type 2 diabetes regimens: a randomized trial. Diabetes Obes Metab 2010;12:916-22
  • Koivisto V, Cleall S, Pontiroli AE, Giugliano D. Comparison of insulin lispro protamine suspension versus insulin glargine once daily in basal-bolus therapies with insulin lispro in type 2 diabetes patients: a prospective randomized open-label trial. Diab Obes Metab 2011;13:1149-57
  • Holman RR, Farmer AJ, Davies MJ, Three-year efficacy of complex regimens in type 2 diabetes. N Engl J Med 2009;361:1736-47
  • Bonora E, Corrao G, Bagnardi V, Prevalence and correlates of post-prandial hyperglycaemia in a large sample of patients with type 2 diabetes mellitus. Diabetologia 2006;49:846-54
  • Giugliano D, Maiorino MI, Bellastella G, Efficacy of insulin analogs in achieving the hemoglobin A1c target of < 7% in type 2 diabetes meta-analysis of randomized controlled trials. Diabetes Care 2011;34:510-17
  • Pontiroli AE, Miele L, Morabito A. Increase of body weight during the first year of intensive insulin treatment in type 2 diabetes. Systematic review and meta-analysis. Diab Obes Metab 2011;13:1008-19
  • Bolli GB, Lucidi P, Porcellati F, Fanelli CG. Pivotal role of timely basal insulin replacement after metformin failure in sustaining long-term blood glucose control at a target in type 2 diabetes. Diabetes Care 2011;34(Suppl 2):S220-S2244
  • Lebovitz HE. Insulin: potential negative consequences of early routine use in patients with type 2 diabetes. Diabetes Care 2011;34(Suppl 2):S225-30
  • Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008;358:2545-59
  • ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008;358:2560-72
  • Duckworth W, Abraira C, Moritz T, Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med 2009;360:129-39
  • Rhoads GG, Kosiborod M, Nesto RW, Comparison of incidence of acute myocardial infarction in patients with type 2 diabetes mellitus following initiation of neutral protamine Hagedorn insulin versus insulin glargine. Am J Cardiol 2009;104:910-16
  • Raz I, Wilson PW, Strojek K, Effects of prandial versus fasting glycemia on cardiovascular outcomes in type 2 diabetes: the HEART2D trial. Diabetes Care 2009;32:381-6
  • Raz I, Ceriello A, Wilson PW, Post hoc subgroup analysis of the HEART2D trial demonstrates lower cardiovascular risk in older patients targeting postprandial versus fasting/premeal glycemia. Diabetes Care 2011;34:1511-13
  • Jonassen I, Havelund S, Ribel U, Insulin degludec is a new generation ultra-long acting basal insulin with a unique mechanism of protraction based on multi-hexamer formation. Diabetes 2010;59(Suppl 1):A11
  • Zinman B, Fulcher G, Rao PV, Insulin degludec, an ultra-long-acting basal insulin, once a day or three times a week versus insulin glargine once a day in patients with type 2 diabetes: a 16-week, randomised, open-label, phase II trial. Lancet 2011;377:924-31
  • Heise T, Tack CJ, Cuddihy R, A new-generation ultra-long-acting basal insulin with a bolus boost compared with insulin glargine in insulin-naive people with type 2 diabetes: a randomized, controlled trial. Diabetes Care 2011;34:669-74
  • Scholtz HE, Pretorius SG, Wessels DH, Becker RHA. Pharmacokinetic and glucodynamic variability: assessment of insulin glargine, NPH insulin and insulin ultralente in healthy volunteers using a euglycaemic clamp technique. Diabetologia 2005;48:1988-95
  • Siegelaar SE, Holleman F, Hoekstra JB, DeVries JH. Glucose variability; does it matter? Endocr Rev 2010;31:171-82
  • Drug Prices. Bellvue, WA Drugstore.com,2011. Available from: www.drugstore.com [Last accessed 14 December 2011]
  • Hermansen K, Davies M. Does insulin detemir have a role in reducing risk of insulin-associated weight gain? Diabetes Obes Metab 2007;9:209-17
  • Malone JK, Kerr LF, Campaigne BN, LisproMixture- Glargine Study Group. Combined therapy with insulin lispro Mix 75/25 plus metformin or insulin glargine plus metformin: a 16-week, randomized, open-label, crossover study in patients with type 2 diabetes beginning insulin therapy. Clin Ther 2004;26:2034-44
  • Malone JK, Bai S, Campaigne BN, Twice-daily premixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes. Diabet Med 2005;22:374-81
  • Raskin P, Allen E, Hollander P, INITIATE Study Group. Initiating insulin therapy in type 2 Diabetes: a comparison of biphasic and basal insulin analogs. Diabetes Care 2005;28:260-5
  • Kann PH, Wascher T, Zackova V, Starting insulin therapy in type 2 diabetes: twice-daily biphasic insulin Aspart 30 plus metformin versus once-daily insulin glargine plus glimepiride. Exp Clin Endocrinol Diabetes 2006;114:527-32
  • Jacober SJ, Scism-Bacon JL, Zagar AJ. A comparison of intensive mixture therapy with basal insulin therapy in insulin-naive patients with type 2 diabetes receiving oral antidiabetes agents. Diabetes Obes Metab 2006;8:448-55
  • Kazda C, Hulstrunk H, Helsberg K, Prandial insulin substitution with insulin lispro or insulin lispro mid mixture vs. basal therapy with insulin glargine: a randomized controlled trial in patients with type 2 diabetes beginning insulin therapy. J Diabetes Complications 2006;20:145-52
  • Holman RR, Thorne KI, Farmer AJ, 4- T Study Group. Addition of biphasic, prandial, or basal insulin to oral therapy in type 2 diabetes. N Engl J Med 2007;357:1716-30
  • Robbins DC, Beisswenger PJ, Ceriello A, Mealtime 50/50 basal + prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and preand postprandial blood glucose levels in patients with type 2 diabetes: a multinational, 24-week, randomized, open-label, parallel-group comparison. Clin Ther 2007;29:2349-64
  • Rosenstock J, Ahmann AJ, Colon G, Advancing insulin therapy in type 2 diabetes previously treated with glargine plus oral agents: prandial premixed (insulin lisproprotamine suspension/lispro) versus basal/ bolus (glargine/lispro) therapy. Diabetes Care 2008;31:20-5
  • Liebl A, Prager R, Binz K, PREFER Study Group. Comparison of insulin analogue regimens in people with type 2 diabetes mellitus in the PREFER Study: a randomized controlled trial. Diabetes Obes Metab 2009;11:45-52
  • Buse JB, Wolffenbuttel BH, Herman WH, DURAbility of basal versus lispro mix 75/25 insulin efficacy (DURABLE) trial 24-week results: safety and efficacy of insulin lispro mix 75/25 versus insulin glargine added to oral antihyperglycemic drugs in patients with type 2 diabetes. Diabetes Care 2009;32:1007-13
  • Strojek K, Bebakar WM, Khutsoane DT, Once-daily initiation with biphasic insulin aspart 30 versus insulin glargine in patients with type 2 diabetes inadequately controlled with oral drugs: an open-label, multinational RCT. Curr Med Res Opin 2009;25:2887-94
  • Holman RR, Farmer AJ, Davies MJ, 4-T Study Group. Three-year efficacy of complex insulin regimens in type 2 diabetes. N Engl J Med 2009;361:1736-47

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.