352
Views
36
CrossRef citations to date
0
Altmetric
Original Research

Extracellular DNA oxidation stimulates activation of NRF2 and reduces the production of ROS in human mesenchymal stem cells

, , PhD, , PhD, , , PhD, , , PhD, , PhD, , PhD, , PhD, , & , PhD show all
Pages S85-S97 | Published online: 18 May 2012

Bibliography

  • Niagara MI, Haider HKH, Jiang S, Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart. Circ Res 2007;100(4):545-55
  • Toma C, Pittenger MF, Cahill KS, Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 2002;1:93-8
  • Haider HKH, Ashraf M. Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation. J Mol Cell Cardiol 2008;45(4):554-66
  • Fleischhacker M, Schmidt B. Circulating nucleic acids (CNAs) and cancer–a survey. Biochim Biophys Acta 2007;1775(1):181-232
  • Ermakov AV, Konkova MS, Kostyuk SV, Oxidative stress as a significant factor for development of an adaptive response in irradiated and nonirradiated human lymphocytes after inducing the bystander effect by low-dose X-radiation. Mutat Res 2009;669(1-2):155-61
  • Ermakov AV, Konkova MS, Kostyuk SV, An extracellular DNA mediated bystander effect produced from low dose irradiated endothelial cells. Mutat Res 2011;712(1-2):1-10
  • Kostyuk SV, Ermakov AV, Alekseeva AY, Role of extracellular DNA oxidative modification in radiation induced bystander effects in human endotheliocytes. Mutat Res 2012;729(1-2):52-60
  • Jahr S, Hentze H, Englisch S, DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells. Cancer Res 2001;61(4):1659-65
  • Anker P, Strong M, Maurice PA. Spontaneous release of DNA by human blood lymphocytes as shown in vitro system. Cancer Res 1975;35:2375-82
  • Adams DH, Diaz N, Gahan PB. In vitro stimulation by tumour cell media of [3H]-thymidine incorporation by mouse spleen lymphocytes. Cell Biochem Funct 1997;15:119-26
  • Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis 2000;21(3):361-70
  • Malins DC, Haimanot R. Major alterations in the nucleotide structure of DNA in cancer of the female breast. Cancer Res 1991;51:5430-2
  • Matsui A, Ikeda T, Enomoto K, Increased formation of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes. Cancer Lett 2000;151:87-95
  • Musarrat J, Arezina-Wilson J, Wani AA. Prognostic and aetiological relevance of 8-hydroxyguanosine in human breast carcinogenesis. Eur J Cancer 1996;32A:1209-14
  • Ermakov AV, Kon'kova MS, Kostiuk SV, The response of human cancer stem cells on low-dose X-ray exposure. Radiats Biol Radioecol 2009;49(5):528-37
  • Cuda G, Paterno R, Ceravolo R, Protection of human endothelial cells from oxidative stress: role of Ras-ERK1/2 signaling. Circulation 2002;105(8):968-74
  • Schneider JE, Price S, Maidt L, Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakage. Nucleic Acids Res 1990;18(3):631-5
  • Singh R, Farmer PB. Liquid chromatography-electrospray ionization-mass spectrometry: the future of DNA adduct detection. Carcinogenesis 2006;27(2):178-96
  • Cadet T, Delatour T, Douki D, Sauvaigo, hydroxyl radicals and DNA base damage. Mutat Res 1999;424:9-21
  • Burney S, Caulfield JL, Niles JC, The chemistry of DNA damage from nitric oxide and peroxynitrite. Mutat Res 1999;424:37-49
  • Kaspar JW, Niture SK, Jaiswal AK. Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radic Biol Med 2009;47(9):1304-9
  • Veiko N, Bulycheva NA, Roginko OA, Ribosomal repeat in cell free DNA as a marker for cell death. Biochem (Moscow) Suppl B Biomed Chem 2008;2(2):198-207
  • Veiko NN, Shubaeva NO, Ivanova SM, Blood serum DNA in patients with rheumatoid arthritis is considerably enriched with fragments of ribosomal repeats containing immunostimulatory CpG-motifs. Bull Exp Biol Med 2006;142(3):313-16
  • Bulicheva N, Fidelina O, Mkrtumova N, Effect of cell-free DNA of patients with cardiomyopathy and rDNA on the frequency of contraction of electrically paced neonatal rat ventricular myocytes in culture. Ann NY Acad Sci 2008;1137:273-7
  • Guz J, Foksinski M, Siomek A, The relationship between 8-oxo-7, 8-dihydro-2'-deoxyguanosine level and extent of cytosine methylation in leukocytes DNA of healthy subjects and in patients with colon adenomas and carcinomas. Mutat Res 2008;640(1-2):170-3
  • Mangal D, Vudathala D, Park JH, Analysis of 7, 8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress. Chem Res Toxicol 2009;22(5):788-97
  • Yoshida H, Nishikawa M, Kiyota T, Increase in CpG DNA-induced inflammatory responses by DNA oxidation in macrophages and mice. Free Radic Biol Med 2011;51(2):424-31
  • Schmidt MV, Brune B, von Knethen A. The nuclear hormone receptor PPARgamma as a therapeutic target in major diseases. Sci World J 2010;10:2181-97
  • Gummersbach C, Hemmrich K, Kroncke KD, New aspects of adipogenesis: radicals and oxidative stress. Differentiation 2009;77(2):115-20
  • Park SH, Choi HJ, Yang H, Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma. J Biol Chem 2010;285(46):35330-9
  • Ara J, Ali R. Reactive oxygen species modified DNA fragments of varying size are the preferred antigen for human anti-DNA autoantibodies. Immunol Lett 1992;34(3):195-200
  • Frenkel K, Karkoszka J, Kim E, Recognition of oxidized DNA bases by sera of patients with inflammatory diseases. Free Radic Biol Med 1993;14(5):483-94
  • Frenkel K, Karkoszka J, Glassman T, Serum autoantibodies recognizing 5-hydroxymethyl-2'-deoxyuridine, an oxidized DNA base, as biomarkers of cancer risk in women. Cancer Epidemiol Biomarkers Prev 1998;7(1):49-57
  • Seedhouse CH, Margison GP, Hendry JH, Anti-8-oxo-2'-deoxyguanosine phage antibodies: isolation, characterization, and relationship to disease states. Biochem Biophys Res Commun 2001;280(3):595-604

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.