Stem-cell therapy for erectile dysfunction

Bibliography

• NIH Consensus Conference. Impotence. NIH consensus development panel on impotence. JAMA 1993;270:83-90
   PubMed Web of Science ®Google Scholar
• Sanchez-Cruz JJ, Cabrera-Leon A, Martin-Morales A, et al. Male erectile dysfunction and health-related quality of life. Eur Urol 2003;44:245-53
   PubMed Web of Science ®Google Scholar
• Sand MS, Fisher W, Rosen R, et al. Erectile dysfunction and constructs of masculinity and quality of life in the multinational Men's Attitudes to Life Events and Sexuality (MALES) study. J Sex Med 2008;5:583-94
   PubMed Web of Science ®Google Scholar
• Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int 1999;84:50-6
   PubMed Web of Science ®Google Scholar
• Shamloul R, Ghanem H. Erectile dysfunction. Lancet 2013;381:153-65
   PubMed Web of Science ®Google Scholar
• Ponholzer A, Temml C, Mock K, et al. Prevalence and risk factors for erectile dysfunction in 2869 men using a validated questionnaire. Eur Urol 2005;47:80-5
   PubMed Web of Science ®Google Scholar
• Lewis RW, Fugl-Meyer KS, Corona G, et al. Definitions/epidemiology/risk factors for sexual dysfunction. J Sex Med 2010;7:1598-607
   PubMed Web of Science ®Google Scholar
• Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001;414:782-7
   PubMed Web of Science ®Google Scholar
• Lam DW, LeRoith D. The worldwide diabetes epidemic. Curr Opin Endocrinol Diabetes Obes 2012;19:93-6
   PubMed Web of Science ®Google Scholar
• Carvalheira AA, Pereira NM, Maroco J, et al. Dropout in the treatment of erectile dysfunction with PDE5: a study on predictors and a qualitative analysis of reasons for discontinuation. J Sex Med 2012;9:2361-9
   PubMed Web of Science ®Google Scholar
• Corona G, Mondaini N, Ungar A, et al. Phosphodiesterase type 5 (PDE5) inhibitors in erectile dysfunction: the proper drug for the proper patient. J Sex Med 2011;8:3418-32
   PubMed Web of Science ®Google Scholar
• McMahon CN, Smith CJ, Shabsigh R. Treating erectile dysfunction when PDE5 inhibitors fail. BMJ 2006;332:589-92
   PubMed Web of Science ®Google Scholar
• Lin CS, Xin ZC, Wang Z, et al. Stem cell therapy for erectile dysfunction: a critical review. Stem Cells Dev 2012;21:343-51
   PubMed Web of Science ®Google Scholar
• Ho CC, Tan HM. Rise of herbal and traditional medicine in erectile dysfunction management. Curr Urol Rep 2011;12:470-8
   PubMedGoogle Scholar
• Yoshimura N, Kato R, Chancellor MB, et al. Gene therapy as future treatment of erectile dysfunction. Expert Opin Biol Ther 2010;10:1305-14
   PubMed Web of Science ®Google Scholar
• McCullough AR, Barada JH, Fawzy A, et al. Achieving treatment optimization with sildenafil citrate (Viagra) in patients with erectile dysfunction. Urology 2002;60:28-38
   PubMed Web of Science ®Google Scholar
• Phe V, Roupret M. Erectile dysfunction and diabetes: a review of the current evidence-based medicine and a synthesis of the main available therapies. Diabetes Metab 2012;38:1-13
   PubMed Web of Science ®Google Scholar
• Kendirci M, Hellstrom WJ. Current concepts in the management of erectile dysfunction in men with prostate cancer. Clin Prostate Cancer 2004;3:87-92
   PubMedGoogle Scholar
• Lin G, Qiu X, Fandel TM, et al. Improved penile histology by phalloidin stain: circular and longitudinal cavernous smooth muscles, dual-endothelium arteries, and erectile dysfunction-associated changes. Urology 2011;78:970, e1-8
   PubMedGoogle Scholar
• Lue TF. Erectile dysfunction. N Engl J Med 2000;342:1802-13
   PubMed Web of Science ®Google Scholar
• Lin CS, Lin G, Lue TF. Cyclic nucleotide signaling in cavernous smooth muscle. J Sex Med 2005;2:478-91
   PubMed Web of Science ®Google Scholar
• Hurt KJ, Musicki B, Palese MA, et al. Akt-dependent phosphorylation of endothelial nitric-oxide synthase mediates penile erection. Proc Natl Acad Sci USA 2002;99:4061-6
   PubMed Web of Science ®Google Scholar
• Lin CS, Lue TF. Cyclic nucleotide signaling in vascular and cavernous smooth muscle: aging-related changes. In: Bittar E, editor. Advances in cell aging and gerontology. (Volume 16). Elsevier, Amsterdam; 2004. p. 57-106
   Google Scholar
• Brock G, Hsu GL, Nunes L, et al. The anatomy of the tunica albuginea in the normal penis and Peyronie's disease. J Urol 1997;157:276-81
   PubMed Web of Science ®Google Scholar
• Gholami SS, Gonzalez-Cadavid NF, Lin CS, et al. Peyronie's disease: a review. J Urol 2003;169:1234-41
   PubMed Web of Science ®Google Scholar
• Garaffa G, Trost LW, Serefoglu EC, et al. Understanding the course of Peyronie's disease. Int J Clin Pract 2013;67:781-8
   PubMed Web of Science ®Google Scholar
• Castiglione F, Hedlund P, Van der Aa F, et al. Intratunical injection of human adipose tissue-derived stem cells prevents fibrosis and is associated with improved erectile function in a rat model of Peyronie's disease. Eur Urol 2013;63:551-60
   PubMed Web of Science ®Google Scholar
• Ma L, Yang Y, Sikka SC, et al. Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction. Proc Natl Acad Sci USA 2012;109:2090-5
   PubMed Web of Science ®Google Scholar
• National Diabetes Statistics, 2011. National Diabetes Information Clearinghouse. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health. Available from: http://diabetes.niddk.nih.gov/dm/pubs/statistics/index.aspx [Last accessed 5 August 2013]
   Google Scholar
• Feldman HA, Goldstein I, Hatzichristou DG, et al. Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study. J Urol 1994;151:54-61
   PubMed Web of Science ®Google Scholar
• Fonseca V, Seftel A, Denne J, et al. Impact of diabetes mellitus on the severity of erectile dysfunction and response to treatment: analysis of data from tadalafil clinical trials. Diabetologia 2004;47:1914-23
   PubMed Web of Science ®Google Scholar
• Penson DF, Latini DM, Lubeck DP, et al. Do impotent men with diabetes have more severe erectile dysfunction and worse quality of life than the general population of impotent patients? Results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction (ExCEED) database. Diabetes Care 2003;26:1093-9
   PubMed Web of Science ®Google Scholar
• Dashwood MR, Crump A, Shi-Wen X, et al. Identification of neuronal nitric oxide synthase (nNOS) in human penis: a potential role of reduced neuronally-derived nitric oxide in erectile dysfunction. Curr Pharm Biotechnol 2011;12:1316-21
   PubMed Web of Science ®Google Scholar
• Zhou F, Xin H, Liu T, et al. Effects of icariside II on improving erectile function in rats with streptozotocin-induced diabetes. J Androl 2012;33:832-44
   PubMed Web of Science ®Google Scholar
• Cellek S, Foxwell NA, Moncada S. Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. Diabetes 2003;52:2353-62
   PubMed Web of Science ®Google Scholar
• Qiu X, Lin G, Xin Z, et al. Effects of low-energy shockwave therapy on the erectile function and tissue of a diabetic rat model. J Sex Med 2013;10:738-46
   PubMed Web of Science ®Google Scholar
• Albersen M, Lin G, Fandel TM, et al. Functional, metabolic, and morphologic characteristics of a novel rat model of type 2 diabetes-associated erectile dysfunction. Urology 2011;78:476, e1-8
   PubMedGoogle Scholar
• Ning H, Lin G, Lue TF, et al. A coculture system of cavernous endothelial and smooth muscle cells. Int J Impot Res 2013;25:63-8
   PubMed Web of Science ®Google Scholar
• Ning H, Qiu X, Baine L, et al. Effects of high glucose on human cavernous endothelial cells. Urology 2012;80:1162, e7-11
   PubMedGoogle Scholar
• Jemal A, Siegel R, Xu J, et al. Cancer statistics, 2010. CA Cancer J Clin 2010;60:277-300
   PubMed Web of Science ®Google Scholar
• Brandeis J, Pashos CL, Henning JM, et al. A nationwide charge comparison of the principal treatments for early stage prostate carcinoma. Cancer 2000;89:1792-9
   PubMed Web of Science ®Google Scholar
• Dean RC, Lue TF. Neuroregenerative strategies after radical prostatectomy. Rev Urol 2005;7(Suppl 2):S26-32
   Google Scholar
• Kendirci M, Bejma J, Hellstrom WJ. Update on erectile dysfunction in prostate cancer patients. Curr Opin Urol 2006;16:186-95
   PubMed Web of Science ®Google Scholar
• Resnick MJ, Koyama T, Fan KH, et al. Long-term functional outcomes after treatment for localized prostate cancer. N Engl J Med 2013;368:436-45
   PubMed Web of Science ®Google Scholar
• Walsh PC, Donker PJ. Impotence following radical prostatectomy: insight into etiology and prevention. J Urol 1982;128:492-7
   PubMed Web of Science ®Google Scholar
• Ficarra V, Novara G, Ahlering TE, et al. Systematic review and meta-analysis of studies reporting potency rates after robot-assisted radical prostatectomy. Eur Urol 2012;62:418-30
   PubMed Web of Science ®Google Scholar
• Pardo Y, Guedea F, Aguilo F, et al. Quality-of-life impact of primary treatments for localized prostate cancer in patients without hormonal treatment. J Clin Oncol 2010;28:4687-96
   PubMed Web of Science ®Google Scholar
• Fode M, Ohl DA, Ralph D, et al. Penile rehabilitation after radical prostatectomy: what the evidence really says. BJU Int 2013; Epub ahead of print
   PubMed Web of Science ®Google Scholar
• Albersen M, Kendirci M, Van der Aa F, et al. Multipotent stromal cell therapy for cavernous nerve injury-induced erectile dysfunction. J Sex Med 2012;9:385-403
   PubMed Web of Science ®Google Scholar
• Ferrini MG, Davila HH, Kovanecz I, et al. Vardenafil prevents fibrosis and loss of corporal smooth muscle that occurs after bilateral cavernosal nerve resection in the rat. Urology 2006;68:429-35
   PubMed Web of Science ®Google Scholar
• Klein LT, Miller MI, Buttyan R, et al. Apoptosis in the rat penis after penile denervation. J Urol 1997;158:626-30
   PubMed Web of Science ®Google Scholar
• Lysiak JJ, Yang SK, Klausner AP, et al. Tadalafil increases Akt and extracellular signal-regulated kinase 1/2 activation, and prevents apoptotic cell death in the penis following denervation. J Urol 2008;179:779-85
   PubMed Web of Science ®Google Scholar
• Leungwattanakij S, Bivalacqua TJ, Usta MF, et al. Cavernous neurotomy causes hypoxia and fibrosis in rat corpus cavernosum. J Androl 2003;24:239-45
   PubMed Web of Science ®Google Scholar
• Hu WL, Hu LQ, Song J, et al. Fibrosis of corpus cavernosum in animals following cavernous nerve ablation. Asian J Androl 2004;6:111-6
   PubMed Web of Science ®Google Scholar
• Iacono F, Giannella R, Somma P, et al. Histological alterations in cavernous tissue after radical prostatectomy. J Urol 2005;173:1673-6
   PubMed Web of Science ®Google Scholar
• Carrier S, Hricak H, Lee SS, et al. Radiation-induced decrease in nitric oxide synthase–containing nerves in the rat penis. Radiology 1995;195:95-9
   PubMed Web of Science ®Google Scholar
• Kimura M, Yan H, Rabbani Z, et al. Radiation-induced erectile dysfunction using prostate-confined modern radiotherapy in a rat model. J Sex Med 2011;8:2215-26
   PubMed Web of Science ®Google Scholar
• Lin CS. Phosphodiesterase type 5 regulation in the penile corpora cavernosa. J Sex Med 2009;6(Suppl 3):203-9
   PubMedGoogle Scholar
• Walsh TJ, Hotaling JM, Lue TF, et al. How curved is too curved? The severity of penile deformity may predict sexual disability among men with Peyronie's disease. Int J Impot Res 2013;25:109-12
   PubMed Web of Science ®Google Scholar
• Stecker JF Jr, Devine CJ Jr. Evaluation of erectile dysfunction in patients with Peyronie's disease. J Urol 1984;132:680-1
   PubMed Web of Science ®Google Scholar
• Lopez JA, Jarow JP. Penile vascular evaluation of men with Peyronie's disease. J Urol 1993;149:53-5
   PubMed Web of Science ®Google Scholar
• Bivalacqua TJ, Diner EK, Novak TE, et al. A rat model of Peyronie's disease associated with a decrease in erectile activity and an increase in inducible nitric oxide synthase protein expression. J Urol 2000;163:1992-8
   PubMed Web of Science ®Google Scholar
• Martinez D, Ercole CE, Hakky TS, et al. Peyronie's disease: still a surgical disease. Adv Urol 2012;2012:206284
   PubMedGoogle Scholar
• Kadioglu A, Sanli O, Akman T, et al. Graft materials in Peyronie's disease surgery: a comprehensive review. J Sex Med 2007;4:581-95
   PubMed Web of Science ®Google Scholar
• Bahk JY, Jung JH, Han H, et al. Treatment of diabetic impotence with umbilical cord blood stem cell intracavernosal transplant: preliminary report of 7 cases. Exp Clin Transplant 2010;8:150-60
   PubMed Web of Science ®Google Scholar
• Richardson MR, Yoder MC. Endothelial progenitor cells: quo vadis? J Mol Cell Cardiol 2011;50:266-72
   PubMed Web of Science ®Google Scholar
• Lin CS, Lue TF. Defining vascular stem cells. Stem Cells Dev 2013;22:1018-26
   PubMed Web of Science ®Google Scholar
• Choi WY, Jeon HG, Chung Y, et al. Isolation and characterization of novel, highly proliferative human CD34/CD73-double-positive testis-derived stem cells for cell therapy. Stem Cells Dev 2013;22:2158-73
   PubMed Web of Science ®Google Scholar
• Lin CS, Xin ZC, Deng CH, et al. Defining adipose tissue-derived stem cells in tissue and in culture. Histol Histopathol 2010;25:807-15
   PubMed Web of Science ®Google Scholar
• Strem BM, Hicok KC, Zhu M, et al. Multipotential differentiation of adipose tissue-derived stem cells. Keio J Med 2005;54:132-41
   PubMed Web of Science ®Google Scholar
• Lin CS, Lue TF. Stem cell therapy for stress urinary incontinence: a critical review. Stem Cells Dev 2012;21:834-43
   PubMed Web of Science ®Google Scholar
• Lin CS, Lin G, Lue TF. Allogeneic and xenogeneic transplantation of adipose-derived stem cells in immunocompetent recipients without immunosuppressants. Stem Cells Dev 2012;21:2770-8
   PubMed Web of Science ®Google Scholar
• Qiu X, Villalta J, Ferretti L, et al. Effects of intravenous injection of adipose-derived stem cells in a rat model of radiation therapy-induced erectile dysfunction. J Sex Med 2012;9:1834-41
   PubMed Web of Science ®Google Scholar
• Qiu X, Fandel TM, Ferretti L, et al. Both immediate and delayed intracavernous injection of autologous adipose-derived stromal vascular fraction enhances recovery of erectile function in a rat model of cavernous nerve injury. Eur Urol 2012;62:720-7
   PubMed Web of Science ®Google Scholar
• El-Sakka AI, Hassan MU, Nunes L, et al. Histological and ultrastructural alterations in an animal model of Peyronie's disease. Br J Urol 1998;81:445-52
   PubMedGoogle Scholar
• Lin CS, Lue TF. Adipose-derived stem cells for the treatment of Peyronie's disease? Eur Urol 2013;63:561-2
   PubMed Web of Science ®Google Scholar
• Fandel TM, Albersen M, Lin G, et al. Recruitment of intracavernously injected adipose-derived stem cells to the major pelvic ganglion improves erectile function in a rat model of cavernous nerve injury. Eur Urol 2012;61:201-10
   PubMed Web of Science ®Google Scholar
• Lin G, Qiu X, Fandel T, et al. Tracking intracavernously injected adipose-derived stem cells to bone marrow. Int J Impot Res 2011;23:268-75
   PubMed Web of Science ®Google Scholar
• Bochinski D, Lin GT, Nunes L, et al. The effect of neural embryonic stem cell therapy in a rat model of cavernosal nerve injury. BJU Int 2004;94:904-9
   PubMed Web of Science ®Google Scholar
• Kim SJ, Choi SW, Hur KJ, et al. Synergistic effect of mesenchymal stem cells infected with recombinant adenovirus expressing human BDNF on erectile function in a rat model of cavernous nerve injury. Korean J Urol 2012;53:726-32
   PubMedGoogle Scholar
• Piao S, Kim IG, Lee JY, et al. Therapeutic effect of adipose-derived stem cells and BDNF-immobilized PLGA membrane in a rat model of cavernous nerve injury. J Sex Med 2012;9:1968-79
   PubMed Web of Science ®Google Scholar
• Kim IG, Piao S, Lee JY, et al. Effect of an adipose-derived stem cell and nerve growth factor-incorporated hydrogel on recovery of erectile function in a rat model of cavernous nerve injury. Tissue Eng Part A 2013;19:14-23
   PubMed Web of Science ®Google Scholar
• Jeong HH, Piao S, Ha JN, et al. Combined therapeutic effect of udenafil and adipose-derived stem cell (ADSC)/brain-derived neurotrophic factor (BDNF)-membrane system in a rat model of cavernous nerve injury. Urology 2013;81:1108, e7-14
   PubMedGoogle Scholar
• You D, Jang MJ, Lee J, et al. Periprostatic implantation of human bone marrow-derived mesenchymal stem cells potentiates recovery of erectile function by intracavernosal injection in a rat model of cavernous nerve injury. Urology 2013;81:104-10
   PubMed Web of Science ®Google Scholar
• You D, Jang MJ, Lee J, et al. Comparative analysis of periprostatic implantation and intracavernosal injection of human adipose tissue-derived stem cells for erectile function recovery in a rat model of cavernous nerve injury. Prostate 2013;73:278-86
   PubMed Web of Science ®Google Scholar
• Lin G, Albersen M, Harraz AM, et al. Cavernous nerve repair with allogenic adipose matrix and autologous adipose-derived stem cells. Urology 2011;77:1509, e1-8
   PubMedGoogle Scholar
• Lin G, Wang G, Banie L, et al. Treatment of stress urinary incontinence with adipose tissue-derived stem cells. Cytotherapy 2010;12:88-95
   PubMed Web of Science ®Google Scholar
• Huang YC, Shindel AW, Ning H, et al. Adipose derived stem cells ameliorate hyperlipidemia associated detrusor overactivity in a rat model. J Urol 2010;183:1232-40
   PubMed Web of Science ®Google Scholar
• Lue TF, Schmidt RA, Tanagho EA. Electrostimulation and penile erection. Urol Int 1985;40:60-4
   PubMed Web of Science ®Google Scholar
• Lin CS, Xin ZC, Dai J, et al. Commonly used mesenchymal stem cell markers and tracking labels: limitations and challenges. Histol Histopathol 2013;28:1109-16
   PubMed Web of Science ®Google Scholar
• Kendirci M, Trost L, Bakondi B, et al. Transplantation of nonhematopoietic adult bone marrow stem/progenitor cells isolated by p75 nerve growth factor receptor into the penis rescues erectile function in a rat model of cavernous nerve injury. J Urol 2010;184:1560-6
   PubMed Web of Science ®Google Scholar
• Albersen M, Fandel TM, Lin G, et al. Injections of adipose tissue-derived stem cells and stem cell lysate improve recovery of erectile function in a rat model of cavernous nerve injury. J Sex Med 2010;7:3331-40
   PubMed Web of Science ®Google Scholar
• Zhang H, Ning H, Banie L, et al. Adipose tissue-derived stem cells secrete CXCL5 cytokine with chemoattractant and angiogenic properties. Biochem Biophys Res Commun 2010;402:560-4
   PubMed Web of Science ®Google Scholar
• Zhang H, Yang R, Wang Z, et al. Adipose tissue-derived stem cells secrete CXCL5 cytokine with neurotrophic effects on cavernous nerve regeneration. J Sex Med 2011;8:437-46
   PubMed Web of Science ®Google Scholar
• Albersen M, Berkers J, Dekoninck P, et al. Expression of a distinct set of chemokine receptors in adipose tissue-derived stem cells is responsible for in vitro migration toward chemokines appearing in the major pelvic ganglion following cavernous nerve injury. Sex Med 2013;1:3-15
   Google Scholar
• Nishimatsu H, Suzuki E, Kumano S, et al. Adrenomedullin mediates adipose tissue-derived stem cell-induced restoration of erectile function in diabetic rats. J Sex Med 2012;9:482-93
   PubMed Web of Science ®Google Scholar
• Ning H, Liu G, Lin G, et al. Fibroblast growth factor 2 promotes endothelial differentiation of adipose tissue-derived stem cells. J Sex Med 2009;6:967-79
   PubMed Web of Science ®Google Scholar
• Kovanecz I, Rivera S, Nolazco G, et al. Separate or combined treatments with daily sildenafil, molsidomine, or muscle-derived stem cells prevent erectile dysfunction in a rat model of cavernosal nerve damage. J Sex Med 2012;9:2814-26
   PubMed Web of Science ®Google Scholar
• Ryu JK, Tumurbaatar M, Jin HR, et al. Intracavernous delivery of freshly isolated stromal vascular fraction rescues erectile function by enhancing endothelial regeneration in the streptozotocin-induced diabetic mouse. J Sex Med 2012;9:3051-65
   PubMed Web of Science ®Google Scholar
• Qiu X, Sun C, Yu W, et al. Combined strategy of mesenchymal stem cell injection with vascular endothelial growth factor gene therapy for the treatment of diabetes-associated erectile dysfunction. J Androl 2012;33:37-44
   PubMed Web of Science ®Google Scholar
• He Y, He W, Qin G, et al. Transplantation KCNMA1 modified bone marrow-mesenchymal stem cell therapy for diabetes mellitus-induced erectile dysfunction. Andrologia 2013; [Epub ahead of print]
   Web of Science ®Google Scholar
• Sun C, Lin H, Yu W, et al. Neurotrophic effect of bone marrow mesenchymal stem cells for erectile dysfunction in diabetic rats. Int J Androl 2012;35:601-7
   PubMed Web of Science ®Google Scholar
• Qiu X, Lin H, Wang Y, et al. Intracavernous transplantation of bone marrow-derived mesenchymal stem cells restores erectile function of streptozocin-induced diabetic rats. J Sex Med 2011;8:427-36
   PubMed Web of Science ®Google Scholar
• Kim HK, Kim YJ, Kim JT, et al. Alterations in the proangiogenic functions of adipose tissue-derived stromal cells isolated from diabetic rats. Stem Cells Dev 2008;17:669-80
   PubMed Web of Science ®Google Scholar
• Harris LJ, Zhang P, Abdollahi H, et al. Availability of adipose-derived stem cells in patients undergoing vascular surgical procedures. J Surg Res 2010;163:e105-12
   Google Scholar
• Kim Y, de Miguel F, Usiene I, et al. Injection of skeletal muscle-derived cells into the penis improves erectile function. Int J Impot Res 2006;18:329-34
   PubMed Web of Science ®Google Scholar
• Bivalacqua TJ, Deng W, Kendirci M, et al. Mesenchymal stem cells alone or ex vivo gene modified with endothelial nitric oxide synthase reverse age-associated erectile dysfunction. Am J Physiol Heart Circ Physiol 2007;292:H1278-90
   PubMed Web of Science ®Google Scholar
• Nolazco G, Kovanecz I, Vernet D, et al. Effect of muscle-derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat. BJU Int 2008;101:1156-64
   PubMed Web of Science ®Google Scholar
• Fall PA, Izikki M, Tu L, et al. Apoptosis and effects of intracavernous bone marrow cell injection in a rat model of postprostatectomy erectile dysfunction. Eur Urol 2009;56:716-25
   PubMed Web of Science ®Google Scholar
• Garcia MM, Fandel TM, Lin G, et al. Treatment of erectile dysfunction in the obese type 2 diabetic ZDF rat with adipose tissue-derived stem cells. J Sex Med 2010;7:89-98
   PubMed Web of Science ®Google Scholar
• Huang YC, Ning H, Shindel AW, et al. The effect of intracavernous injection of adipose tissue-derived stem cells on hyperlipidemia-associated erectile dysfunction in a rat model. J Sex Med 2010;7:1391-400
   PubMed Web of Science ®Google Scholar
• Abdel Aziz MT, El-Haggar S, Mostafa T, et al. Effect of mesenchymal stem cell penile transplantation on erectile signaling of aged rats. Andrologia 2010;42:187-92
   PubMed Web of Science ®Google Scholar
• Woo JC, Bae WJ, Kim SJ, et al. Transplantation of muscle-derived stem cells into the corpus cavernosum restores erectile function in a rat model of cavernous nerve injury. Korean J Urol 2011;52:359-63
   PubMedGoogle Scholar
• Gou X, He WY, Xiao MZ, et al. Transplantation of endothelial progenitor cells transfected with VEGF165 to restore erectile function in diabetic rats. Asian J Androl 2011;13:332-8
   PubMed Web of Science ®Google Scholar
• Ying C, Yang M, Zheng X, et al. Effects of intracavernous injection of adipose-derived stem cells on cavernous nerve regeneration in a rat model. Cell Mol Neurobiol 2013;33:233-40
   PubMed Web of Science ®Google Scholar