Bibliography
- Chikanza I, Fernandes L. Novel strategies for the treatment of osteoarthritis. Expert Opin Investig Drugs 2000;9:1499-510
- Anitua E, Sanchez M, Orive G, Padilla S. A biological therapy to osteoarthritis treatment using platelet-rich plasma. Expert Opin Biol Ther 2013;13:1161-72
- Roubille C, Pelletier JP, Martel-Pelletier J. New and emerging treatments for osteoarthritis management: will the dream come true with personalized medicine? Expert Opin Pharmacother 2013;14:2059-77
- Buttle DJ, Bramwell H, Hollander AP. Proteolytic mechanisms of cartilage breakdown: a target for arthritis therapy? Clin Mol Pathol 1995;48:M167-77
- Tchetina EV. Developmental mechanisms in articular cartilage degradation in osteoarthritis. Arthritis 2011;2011:683970
- Abrams GD, Frank RM, Fortier LA, Cole BJ. Platelet-rich plasma for articular cartilage repair. Sports Med Arthrosc 2013;21:213-19
- Qi Y, Feng G, Yan W. Mesenchymal stem cell-based treatment for cartilage defects in osteoarthritis. Mol Biol Rep 2012;39:5683-9
- Peterson L, Brittberg M, Kiviranta I, et al. Autologous chondrocyte transplantation. Biomechanics and long-term durability. Am J Sports Med 2002;30:2-12
- Pei M, Chen D, Li J, Wei L. Histone deacetylase 4 promotes TGF-beta1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy. Differentiation 2009;78:260-8
- Nixon AJ, Haupt JL, Frisbie DD, et al. Gene-mediated restoration of cartilage matrix by combination insulin-like growth factor-I/interleukin-1 receptor antagonist therapy. Gene Ther 2005;12:177-86
- Mierisch CM, Cohen SB, Jordan LC, et al. Transforming growth factor-beta in calcium alginate beads for the treatment of articular cartilage defects in the rabbit. Arthroscopy 2002;18:892-900
- Kim YI, Ryu JS, Yeo JE, et al. Overexpression of TGF-beta1 enhances chondrogenic differentiation and proliferation of human synovium-derived stem cells. Biochem Biophys Res Commun 2014;450:1593-9
- Noh MJ, Copeland RO, Yi Y, et al. Pre-clinical studies of retrovirally transduced human chondrocytes expressing transforming growth factor-beta-1 (TG-C). Cytotherapy 2010;12:384-93
- Ha CW, Noh MJ, Choi KB, Lee KH. Initial phase I safety of retrovirally transduced human chondrocytes expressing transforming growth factor-beta-1 in degenerative arthritis patients. Cytotherapy 2012;14:247-56
- Perera JR, Jaiswal PK, Khan WS. The potential therapeutic use of stem cells in cartilage repair. Curr Stem Cell Res Ther 2012;7:149-56
- Lotz M. Cytokines in cartilage injury and repair. Clin Orthop Relat Res 2001;(391 Suppl):S108-15
- Liang YY, Brunicardi FC, Lin X. Smad3 mediates immediate early induction of Id1 by TGF-beta. Cell Res 2009;19:140-8
- Mu Y, Gudey SK, Landstrom M. Non-Smad signaling pathways. Cell Tissue Res 2012;347:11-20
- Walenda G, Abnaof K, Joussen S, et al. TGF-beta1 does not induce senescence of multipotent mesenchymal stromal cells and has similar effects in early and late passages. PLoS One 2013;8:e77656
- Morisset S, Frisbie DD, Robbins PD, et al. IL-1ra/IGF-1 gene therapy modulates repair of microfractured chondral defects. Clin Orthop Relat Res 2007;462:221-8
- Giatsidis G, Dalla Venezia E, Bassetto F. The role of gene therapy in regenerative surgery: updated insights. Plast Reconstr Surg 2013;131:1425-35
- Goldring MB, Tsuchimochi K, Ijiri K. The control of chondrogenesis. J Cell Biochem 2006;97:33-44
- Hennerbichler A, Moutos FT, Hennerbichler D, et al. Interleukin-1 and tumor necrosis factor alpha inhibit repair of the porcine meniscus in vitro. Osteoarthritis Cartilage 2007;15:1053-60
- McNulty AL, Guilak F. Integrative repair of the meniscus: lessons from in vitro studies. Biorheology 2008;45:487-500
- McNulty AL, Weinberg JB, Guilak F. Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus. Clin Orthop Relat Res 2009;467:1557-67
- Wilusz RE, Weinberg JB, Guilak F, McNulty AL. Inhibition of integrative repair of the meniscus following acute exposure to interleukin-1 in vitro. J Orthop Res 2008;26:504-12
- Fernandes JC, Martel-Pelletier J, Pelletier JP. The role of cytokines in osteoarthritis pathophysiology. Biorheology 2002;39:237-46
- Chandrasekhar S, Harvey AK, Hrubey PS. Intra-articular administration of interleukin-1 causes prolonged suppression of cartilage proteoglycan synthesis in rats. Matrix 1992;12:1-10
- Pettipher ER, Higgs GA, Henderson B. Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint. Proc Natl Acad Sci USA 1986;83:8749-53
- van Beuningen HM, van der Kraan PM, Arntz OJ, van den Berg WB. Protection from interleukin 1 induced destruction of articular cartilage by transforming growth factor beta: studies in anatomically intact cartilage in vitro and in vivo. Ann Rheum Dis 1993;52:185-91
- Aigner T, Soder S, Gebhard PM, et al. Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis--structure, chaos and senescence. Nat Clin Pract Rheumatol 2007;3:391-9
- Loeser RF, Shanker G, Carlson CS, et al. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis: studies in a non-human primate model of naturally occurring disease. Arthritis Rheum 2000;43:2110-20
- Fan Z, Bau B, Yang H, et al. Freshly isolated osteoarthritic chondrocytes are catabolically more active than normal chondrocytes, but less responsive to catabolic stimulation with interleukin-1beta. Arthritis Rheum 2005;52:136-43
- Zhen G, Cao X. Targeting TGFbeta signaling in subchondral bone and articular cartilage homeostasis. Trends Pharmacol Sci 2014;35:227-36
- van der Kraan PM, Goumans MJ, Blaney Davidson E, ten Dijke P. Age-dependent alteration of TGF-beta signalling in osteoarthritis. Cell Tissue Res 2012;347:257-65
- Bakker AC, van de Loo FA, van Beuningen HM, et al. Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation. Osteoarthritis Cartilage 2001;9:128-36
- Shinbo T, Fushida S, Tsukada T, et al. Protein-bound polysaccharide K suppresses tumor fibrosis in gastric cancer by inhibiting the TGF-beta signaling pathway. Oncol Rep 2015;33:553-8
- Reichl P, Dengler M, van Zijl F, et al. Signaling of Axl via 14-3-3zeta activates autocrine transforming growth factor-beta signaling in hepatocellular carcinoma. Hepatology 2014. [Epub ahead of print]
- Bu F, Liu X, Li J, et al. TGF-beta1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma. Oncotarget 2014; Epub ahead of print
- Liu S, Jin K, Hui Y, et al. HOXB7 promotes malignant progression by activating the TGF-beta signaling pathway. Cancer Res 2014; Epub ahead of print
- Wang G, Yang X, Jin Y, et al. TGF-beta regulates the proliferation of lung adenocarcinoma cells by inhibiting PIK3R3 expression. Mol Carcinog 2014. [Epub ahead of print]
- Zhang G, Zhao Q, Yu S, et al. Pttg1 inhibits TGFbeta signaling in breast cancer cells to promote their growth. Tumour Biol 2014. [Epub ahead of print]
- Blaney Davidson EN, Vitters EL, van der Kraan PM, van den Berg WB. Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation. Ann Rheum Dis 2006;65:1414-21
- Tepper OM, Mehrara BJ. Gene therapy in plastic surgery. Plast Reconstr Surg 2002;109:716-34
- Heyde M, Partridge KA, Oreffo RO, et al. Gene therapy used for tissue engineering applications. J Pharm Pharmacol 2007;59:329-50
- Thomas CE, Ehrhardt A, Kay MA. Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 2003;4:346-58
- Suerth JD, Labenski V, Schambach A. Alpharetroviral vectors: from a cancer-causing agent to a useful tool for human gene therapy. Viruses 2014;6:4811-38
- Madry H, Cucchiarini M, Terwilliger EF, Trippel SB. Recombinant adeno-associated virus vectors efficiently and persistently transduce chondrocytes in normal and osteoarthritic human articular cartilage. Hum Gene Ther 2003;14:393-402
- Venkatesan JK, Rey-Rico A, Schmitt G, et al. rAAV-mediated overexpression of TGF-beta stably restructures human osteoarthritic articular cartilage in situ. J Transl Med 2013;11:211
- Ulrich-Vinther M, Stengaard C, Schwarz EM, et al. Adeno-associated vector mediated gene transfer of transforming growth factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism. Eur Cells Mater 2005;10:40-50
- Song SU, Cha YD, Han JU, et al. Hyaline cartilage regeneration using mixed human chondrocytes and transforming growth factor-beta1- producing chondrocytes. Tissue Eng 2005;11:1516-26
- Brittberg M, Lindahl A, Nilsson A, et al. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994;331:889-95
- Cavallo C, Filardo G, Mariani E, et al. Comparison of platelet-rich plasma formulations for cartilage healing: an in vitro study. J Bone Joint Surg Am 2014;96:423-9
- van Bergen CJ, Kerkhoffs GM, Ozdemir M, et al. Demineralized bone matrix and platelet-rich plasma do not improve healing of osteochondral defects of the talus: an experimental goat study. Osteoarthritis Cartilage 2013;21:1746-54
- Lee KH, Song SU, Hwang TS, et al. Regeneration of hyaline cartilage by cell-mediated gene therapy using transforming growth factor beta 1-producing fibroblasts. Hum Gene Ther 2001;12:1805-13
- DePalma AF, McKeever CD, Subin DK. Process of repair of articular cartilage demonstrated by histology and autoradiography with tritiated thymidine. Clin Orthop Relat Res 1966;48:229-42
- Shapiro F, Koide S, Glimcher MJ. Cell origin and differentiation in the repair of full-thickness defects of articular cartilage. J Bone Joint Surg Am 1993;75:532-53
- Khaled EG, Saleh M, Hindocha S, et al. Tissue engineering for bone production- stem cells, gene therapy and scaffolds. Open Orthop J 2011;5(Suppl 2):289-95
- van Osch GJ. Osteoarthritis Year in review 2014: highlighting innovations in basic research and clinical applications in regenerative medicine. Osteoarthritis Cartilage 2014;22:2013-16
- Diekman BO, Wu CL, Louer CR, et al. Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis. Cell Transplant 2013;22:1395-408
- Blaney Davidson EN, Vitters EL, van den Berg WB, van der Kraan PM. TGF beta-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7. Arthritis Res Ther 2006;8:R65
- Bowman LC, Grossmann M, Rill D, et al. Interleukin-2 gene-modified allogeneic tumor cells for treatment of relapsed neuroblastoma. Hum Gene Ther 1998;9:1303-11