Hydrogels for oral delivery of therapeutic proteins

Bibliography

• PEPPAS NA, BURES P, LEOBANDUNG W, ICHIKAWA H: Hydrogels in pharmaceutical formulations. Eur.j Pharm. Biopharm. (2000) 50:27–46.
   PubMed Web of Science ®Google Scholar
• •Excellent review article on pharmaceutical applications of hydrogels with large bibliographic information.
   Google Scholar
• GOLDBERG M, GOMEZ-ORELLANA I: Challenges for the oral delivery of macromolecules. Nat. Rev Drug Disc. (2003) 2:289–295.
   PubMed Web of Science ®Google Scholar
• •Recent review of oral delivery studies of proteins, unfortunately with an unbalanced view of one specific system.
   Google Scholar
• TORRES-LUGO M, PEPPAS NA: Transmucosal delivery systems for calcitonin: a review. Biomaterials (2000) 21:1191–1196.
   PubMed Web of Science ®Google Scholar
• LOWMAN AM, PEPPAS NA: Molecularanalysis of interpolymer complexation in graft copolymer networks. Polymer (2000) 41:73–80.
   Web of Science ®Google Scholar
• FOSS AC, PEPPAS NA: Acrylic-based copolymers for oral insulin delivery systems. Polym. Prepr. (2001) 42(2):94–95.
   Google Scholar
• GARCIA M, TORRES-LUGO M, ALONSO MJ, PEPPAS NA: Biointeractions of pH-sensitive poly(methacrylic acid-g-ethylene glycol) hydrogel microspheres with the Caco-2 model cell line. In: New Trends M Polymers for Oral and Parenteral Administration: From Design to Receptors. Barratt G, Duchêne D, Fattal F, Legendre JY (Eds), Editions de Santé, Paris, France (2001):386–389.
   Google Scholar
• TORRES-LUGO M, PEPPAS NA: Preparation and characterization of P (MAA-g-EG) nanospheres for protein delivery applications.' Nanoparticle Res (2002) 4:73–81.
   Web of Science ®Google Scholar
• •Detailed analysis of molecular structure of intelligent hydrogels for protein delivery.
   Google Scholar
• BLANCHETTE J, PARK K, PEPPAS NA: Oral administration of chemotherapeutic agents using complexation hydrogels. In: Biological and Biomimetic Materials - Properties to Function. McKittrick J, Aizenberg J, Orme C, Vekilov P (Eds), MRS, Pittsburgh, PA, USA (2002):218–222.
   Google Scholar
• KIM B, PEPPAS NA: PEG-containing hydrogel microparticles for oral protein delivery applications. Biomed. Microdevices (2003) 5:333–341.
   Web of Science ®Google Scholar
• ICHIKAWA H, PEPPAS NA: Novel complexation hydrogels for oral peptide delivery: M vitro evaluation of their cytocompatibility and insulin-transport enhancing effects using Caco-2 cell monolayers. Biomed. Mater. Res. (2003) 67:609–617.
   Web of Science ®Google Scholar
• ICHIKAWA H, PEPPAS NA: Synthesis and characterization of pH-responsive nanosized hydrogels of poly(methacrylic acid-g-ethylene glycol) for oral peptide delivery. New Trends in Polymers for Oral and Parenteral Administration: From Design to Receptors. Barratt G, Duchêne D, F, Legendre JY (Eds), Editions de Santé, Paris, France (2001):261–264.
   Google Scholar
• LOWMAN AM, MORISHITA M, KAJITA M, NAGAI T, PEPPAS NA: Oral delivery of insulin using pH-responsive complexation gels.' Pharm. Sci. (1999) 88:933–937.
   PubMed Web of Science ®Google Scholar
• ••Pioneering work in the field; first studywith substantial insulin bioavailability in Wistar rats.
   Google Scholar
• MORISHITA M, LOWMAN AM, TAKAYAMA K, NAGAI T, PEPPAS NA: Elucidation of the mechanism of incorporation of insulin in controlled release systems based on complexation polymers. Control. Release (2002) 81:25–32.
   PubMed Web of Science ®Google Scholar
• TORRES-LUGO M, GARCIA M, RECORD R, PEPPAS NA: Physicochemical behavior and cytotoxic effects of P(MAA-g-EG) nanospheres for oral delivery of proteins. Control. Release (2002) 80:197–205.
   PubMed Web of Science ®Google Scholar
• TORRES-LUGO M, GARCIA M, RECORD R, PEPPAS NA: pH-Sensitive hydrogels as gastrointestinal tract absorption enhancers: transport mechanisms of salmon calcitonin and other model molecules using the Caco-2 cell model. Biotechnol Frog. (2002) 18:612–616.
   Google Scholar
• ROBINSON DN, PEPPAS NA: Preparation and characterization of pH-responsive poly(methacrylic acid-g-poly(ethylene glycol) nanospheres. Macromolecules (2002) 35:3668–3674.
   Web of Science ®Google Scholar
• LOWMAN AM, COWANS BA, PEPPAS NA: Investigation of interpolymer complexation in swollen polyelectrolyte networks by solid state NMR spectroscopy. Polym. Sci. Polym. Phys. (2000) 38:2823–2831.
   Web of Science ®Google Scholar
• SCOTT R, WARD JH, PEPPAS NA: Development of acrylate and methacrylate polymer networks for controlled release by photopolymerization technology. In: Handbook of Pharmaceutical Controlled Release Technology Wise DL, Brannon-Peppas L, Klibanov AM, Langer R, Mikos AG, Peppas NA, Trantolo DJ, Wnek GE, Yaszemski MJ (Eds), Dekker, New York, NY, USA (2000):47–64.
   Google Scholar
• BERNKOP-SCHNURCH A, SCERBE-SAIKO A: Synthesis and M vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins. Pharm. Res. (1998) 15:263–269.
   PubMed Web of Science ®Google Scholar
• •Earliest in a series of interesting studies by this Austrian group.
   Google Scholar
• PEPPAS NA; Gels for drug delivery. In: Encyclopedia of Materials: Science and Technology Elsevier, Amsterdam, The Netherlands (2001):3492–3495.
   Google Scholar
• PEPPAS NA, BRANNON-PEPPAS L: Drug delivery biomaterials. In: Encyclopedia of Materials: Science and Technology Elsevier, Amsterdam, The Netherlands (2001):2351–2355.
   Google Scholar
• YAMAMOTO A, TANIGUCHI T, RIKYUU K et al.: Effects of various protease inhibitors on the intestinal absorption and degradation of insulin in rats. Pharm. Res. (1994) 11:1496–1500.
   PubMed Web of Science ®Google Scholar
• MESIHA M, PLAKOGIANNIS F, VEJOSOTH S: Enhanced oral absorption of insulin from desolvated fatty acid-sodium glycocholate emulsions. Int. .1. Pharm. (1994) 111:213–216.
   Web of Science ®Google Scholar
• FASANO A, UZZAU S: Modulation of intestinal tight junctions by zona occludens toxin permits enteral administration of insulin and other macromolecules in an animal model. J. Gin. Invest. (1997) 99:1158–1164.
   PubMed Web of Science ®Google Scholar
• ••Pioneering work on understandingprotein transport by disruption of cell tight junctions.
   Google Scholar
• BERGER J, REIST M, MAYER JM, FELT 0, PEPPAS NA, GURNY R: Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. Eur. I Pharm. Biopharm. (2004) 57:19–34.
   PubMed Web of Science ®Google Scholar
• ••Exceptional review of the importance ofchitosans in the field.
   Google Scholar
• BERGER J, REIST M, MAYER JM, FELT 0, GURNY R: Structure and interaction in chitosan hydrogels formed by complexation of aggregation for biomedical applications. Eur. I Pharm. Biopharm. (2004) 57:35–52.
   PubMed Web of Science ®Google Scholar
• DONINI C, ROBINSON DN, COLOMBO P, GIORDANO F, PEPPAS NA: Preparation of P(MAA-g-EG) nanospheres for pharmaceutical applications. Int. Pharm. (2002) 245:83–91.
   PubMed Web of Science ®Google Scholar
• SIPAHIGIL 0, TORRES-LUGO M, PEPPAS NA: FTIR spectroscopic analysis of protein/carrier interactions in novel protein delivery systems. STP Pharma (2002) 12:345–350.
   Web of Science ®Google Scholar
• NAKAMURA K, MURRAY RJ, JOSEPH JI, PEPPAS NA, MORISHITA M, LOWMAN AM: Oral insulin delivery using P (MAA-g-E G) hydrogels: effects of network morphology on insulin delivery characteristics. Control. Release (2004) 95(3):589–599.
   PubMed Web of Science ®Google Scholar
• STILL JG: Development of oral insulin: progress and current status. Diabetes Metab. Res. Rev (2002) 18\(Suppl. 1):529–537.
   Google Scholar
• KIPNES M, DANDONA P, TRIPATHY D, STILL JG, KOSUTIC G: Control of postprandial plasma glucose by an oral insulin product (HIM2) in patients with type 2 diabetes. Diabetes Care (2003) 26:421–426.
   PubMed Web of Science ®Google Scholar
• •Pioneering work in the field. First clinical study of elevated bioavailability in patients.
   Google Scholar
• KAPITZA C, ARBIT E, ABBAS R et al: Oral insulin: proof of concept in type 2 diabetic patients. (glucose monitoring and insulin delivery). Diabetes (2003) 52\(Suppl. 1):A37.
   Google Scholar
• HUANG Y, EFREMOVA N, PEPPAS NA, LECKBAND DE: Direct measurement of interactions between tethered PEG chains and adsorbed mucin layers. Langmuir (2002) 18:836–845.
   Web of Science ®Google Scholar
• MORISHITA M, GOTO T, PEPPAS NA et al: Mucosal insulin delivery systems based on complexation polymer hydrogels: effect of particle size on insulin enteral absorption. J. Control. Release (2004) 97(1):115–124.
   PubMed Web of Science ®Google Scholar
• PLATE NA, VALUEV IL, SYTOV GA, VALUEV LI; Mucoadhesive polymers with immobilized proteinase inhibitors for oral administration of protein drugs. Biomaterials (2002) 23:1673–1677.
   PubMed Web of Science ®Google Scholar