Strategies to improve non-viral vectors – potential applications in clinical transplantation

Bibliography

• TAN PH, CHAN CL, CHAN C, GEORGE AJ: The evolving role of gene-based treatment in surgery. Br. J. Surg. (2005) 92(12):1466-1480.
   PubMed Web of Science ®Google Scholar
• JAESCHKE H, SMITH CW, CLEMENS MG, GANEY PE, ROTH RA: Mechanisms of inflammatory liver injury: adhesion molecules and cytotoxicity of neutrophils. Toxicol. Appl. Pharmacol. (1996) 139(2):213-226.
   PubMed Web of Science ®Google Scholar
• YAMAGUCHI Y, MATSUMURA F, TAKEYA M et al.: Monocyte chemoattractant protein-1 enhances expression of intercellular adhesion molecule-1 following ischemia-reperfusion of the liver in rats. Hepatology (1998) 27(3):727-734.
   PubMed Web of Science ®Google Scholar
• FANSLOW WC, SIMS JE, SASSENFELD H et al.: Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor. Science (1990) 248(4956):739-742.
   PubMed Web of Science ®Google Scholar
• RAYNER SA, LARKIN DF, GEORGE AJ: TNF receptor secretion after ex vivo adenoviral gene transfer to cornea and effect on in vivo graft survival. Invest. Ophthalmol. Vis. Sci. (2001) 42(7):1568-1573.
   PubMed Web of Science ®Google Scholar
• ZEHR KJ, HERSKOWITZ A, LEE PC et al.: Neutrophil adhesion and complement inhibition prolongs survival of cardiac xenografts in discordant species. Transplantation (1994) 57(6):900-906.
   PubMed Web of Science ®Google Scholar
• ROTH C, KOURILSKY P, OJCIUS DM: Ly-49-independent inhibition of natural killer cell-mediated cytotoxicity by a soluble major histocompatibility complex class I molecule. Eur. J. Immunol. (1994) 24(9):2110-2114.
   PubMed Web of Science ®Google Scholar
• KONDO S, YIN D, MORIMURA T et al.: Transfection with a bcl-2 expression vector protects transplanted bone marrow from chemotherapy-induced myelosuppression. Cancer Res. (1994) 54(11):2928-2933.
   PubMed Web of Science ®Google Scholar
• ZWACKA RM, ZHOU W, ZHANG Y et al.: Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-kappaB activation. Nat. Med. (1998) 4(6):698-704.
   PubMed Web of Science ®Google Scholar
• SPRINGER TA: Adhesion receptors of the immune system. Nature (1990) 346(6283):425-434.
   PubMed Web of Science ®Google Scholar
• ISOBE M, YAGITA H, OKUMURA K, IHARA A: Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science (1992) 255(5048):1125-1127.
   PubMed Web of Science ®Google Scholar
• QIN L, CHAVIN KD, DING Y et al.: Multiple vectors effectively achieve gene transfer in a murine cardiac transplantation model. Immunosuppression with TGF-beta 1 or vIL-10. Transplantation (1995) 59(6):809-816.
   PubMed Web of Science ®Google Scholar
• DEBRUYNE LA, LI K, CHAN SY et al.: Lipid-mediated gene transfer of viral IL-10 prolongs vascularized cardiac allograft survival by inhibiting donor-specific cellular and humoral immune responses. Gene Ther. (1998) 5(8):1079-1087.
   PubMed Web of Science ®Google Scholar
• HANCOCK WW, SAYEGH MH, ZHENG XG et al.: Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection. Proc. Natl. Acad. Sci. USA (1996) 93(24):13967-13972.
   PubMed Web of Science ®Google Scholar
• LENSCHOW DJ, ZENG Y, THISTLETHWAITE JR et al.: Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg. Science (1992) 257(5071):789-792.
   PubMed Web of Science ®Google Scholar
• COMER RM, KING WJ, ARDJOMAND N et al.: Effect of administration of CTLA4-Ig as protein or cDNA on corneal allograft survival. Invest. Ophthalmol. Vis. Sci. (2002) 43(4):1095-1103.
   PubMed Web of Science ®Google Scholar
• GROHMANN U, ORABONA C, FALLARINO F et al.: CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat. Immunol. (2002) 3(11):1097-1101.
   PubMed Web of Science ®Google Scholar
• ALEXANDER AM, CRAWFORD M, BERTERA S et al.: Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes (2002) 51(2):356-365.
   PubMed Web of Science ®Google Scholar
• BEUTELSPACHER SC, PILLAI R, WATSON M et al.: Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression. Eur. J. Immunol. (2006) 36(3):690-700.
   PubMed Web of Science ®Google Scholar
• GAINER AL, SUAREZ-PINZON WL, MIN WP et al.: Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand. Transplantation (1998) 66(2):194-199.
   PubMed Web of Science ®Google Scholar
• TAN PH, BEUTELSPACHER SC, WANG YH et al.: Immunolipoplexes: an efficient, nonviral alternative for transfection of human dendritic cells with potential for clinical vaccination. Mol. Ther. (2005) 11(5):790-800.
   PubMed Web of Science ®Google Scholar
• LU L, LEE WC, TAKAYAMA T et al.: Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL-10, TGF-beta, and CTLA4Ig). J. Leukoc. Biol. (1999) 66(2):293-296.
   PubMed Web of Science ®Google Scholar
• LU L, QIAN S, HERSHBERGER PA et al.: Fas ligand (CD95L) and B7 expression on dendritic cells provide counter-regulatory signals for T cell survival and proliferation. J. Immunol. (1997) 158(12):5676-5684.
   PubMed Web of Science ®Google Scholar
• TAN PH, YATES JB, XUE SA et al.: Creation of tolerogenic human dendritic cells via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression. Blood (2005) 106(9):2936-2943.
   PubMed Web of Science ®Google Scholar
• BRADLEY JA, BOLTON EM, PEDERSEN RA: Stem cell medicine encounters the immune system. Nat. Rev. Immunol. (2002) 2(11):859-871.
   PubMed Web of Science ®Google Scholar
• MANN MJ, GIBBONS GH, HUTCHINSON H et al.: Pressure-mediated oligonucleotide transfection of rat and human cardiovascular tissues. Proc. Natl. Acad. Sci. USA (1999) 96(11):6411-6416.
   PubMed Web of Science ®Google Scholar
• LIU F, SONG Y, LIU D: Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Ther. (1999) 6(7):1258-1266.
   PubMed Web of Science ®Google Scholar
• YANG NS, BURKHOLDER J, ROBERTS B, MARTINELL B, MCCABE D: In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment. Proc. Natl. Acad. Sci. USA (1990) 87(24):9568-9572.
   PubMed Web of Science ®Google Scholar
• KODAMA T, TAN PH, OFFIAH I et al.: Delivery of oligodeoxynucleotides into human saphenous veins: the adjunct effect of ultrasound and microbubbles. Ultrasound Med. Biol. (2005) 31(12):1683-1691.
   PubMed Web of Science ®Google Scholar
• AIHARA H, MIYAZAKI J: Gene transfer into muscle by electroporation in vivo. Nat. Biotechnol. (1998) 16(9):867-870.
   PubMed Web of Science ®Google Scholar
• VILLANUEVA FS, JANKOWSKI RJ, KLIBANOV S et al.: Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells. Circulation (1998) 98(1):1-5.
   PubMed Web of Science ®Google Scholar
• FELGNER PL, GADEK TR, HOLM M et al.: Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc. Natl. Acad. Sci. USA (1987) 84(21):7413-7417.
   PubMed Web of Science ®Google Scholar
• RANGARAJAN PN, VATSALA PG, ASHOK MS et al.: Non-viral ex vivo hepatic gene transfer by in situ lipofection of liver and intraperitoneal transplantation of hepatocytes. Gene (1997) 190(1):217-221.
   PubMed Web of Science ®Google Scholar
• BENIGNI A, TOMASONI S, REMUZZI G: Impediments to successful gene transfer to the kidney in the context of transplantation and how to overcome them. Kidney Int. (2002) 61(1 Suppl.):115-119.
   Google Scholar
• BENHAMOU PY, MORISCOT C, PREVOST P et al.: Standardization of procedure for efficient ex vivo gene transfer into porcine pancreatic islets with cationic liposomes. Transplantation (1997) 63(12):1798-1803.
   PubMed Web of Science ®Google Scholar
• WAGNER E, OGRIS M, ZAUNER W: Polylysine-based transfection systems utilizing receptor-mediated delivery. Adv. Drug Deliv. Rev. (1998) 30(1-3):97-113.
   PubMed Web of Science ®Google Scholar
• KIM JS, MARUYAMA A, AKAIKE T, KIM SW: Terplex DNA delivery system as a gene carrier. Pharm. Res. (1998) 15(1):116-121.
   PubMed Web of Science ®Google Scholar
• WU CH, WILSON JM, WU GY: Targeting genes: delivery and persistent expression of a foreign gene driven by mammalian regulatory elements in vivo. J. Biol. Chem. (1989) 264(29):16985-16987.
   PubMed Web of Science ®Google Scholar
• SCHAFFER DV, LAUFFENBURGER DA: Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery. J. Biol. Chem. (1998) 273(43):28004-28009.
   PubMed Web of Science ®Google Scholar
• KUKOWSKA-LATALLO JF, BIELINSKA AU, JOHNSON J et al.: Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. Proc. Natl. Acad. Sci. USA (1996) 93(10):4897-4902.
   PubMed Web of Science ®Google Scholar
• TANG MX, REDEMANN CT, SZOKA FC JR: In vitro gene delivery by degraded polyamidoamine dendrimers. Bioconjug. Chem. (1996) 7(6):703-714.
   PubMed Web of Science ®Google Scholar
• GODBEY WT, WU KK, HIRASAKI GJ, MIKOS AG: Improved packing of poly(ethylenimine)/DNA complexes increases transfection efficiency. Gene Ther. (1999) 6(8):1380-1388.
   PubMed Web of Science ®Google Scholar
• DIEBOLD SS, KURSA M, WAGNER E, COTTEN M, ZENKE M: Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells. J. Biol. Chem. (1999) 274(27):19087-19094.
   PubMed Web of Science ®Google Scholar
• OGRIS M, STEINLEIN P, KURSA M et al.: The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. (1998) 5(10):1425-1433.
   PubMed Web of Science ®Google Scholar
• QIN L, PAHUD DR, DING Y et al.: Efficient transfer of genes into murine cardiac grafts by Starburst polyamidoamine dendrimers. Hum. Gene Ther. (1998) 9(4):553-560.
   PubMed Web of Science ®Google Scholar
• TRUONG-LE VL, AUGUST JT, LEONG KW: Controlled gene delivery by DNA-gelatin nanospheres. Hum. Gene Ther. (1998) 9(12):1709-1717.
   PubMed Web of Science ®Google Scholar
• VAN DE WETERING P, MORET EE, SCHUURMANS-NIEUWENBROEK NM, VAN STEENBERGEN MJ, HENNINK WE: Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery. Bioconjug. Chem. (1999) 10(4):589-597.
   PubMed Web of Science ®Google Scholar
• VAN DER WOUDE I, WAGENAAR A, MEEKEL AA et al.: Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery. Proc. Natl. Acad. Sci. USA (1997) 94(4):1160-1165.
   PubMed Web of Science ®Google Scholar
• SHEA LD, SMILEY E, BONADIO J, MOONEY DJ: DNA delivery from polymer matrices for tissue engineering. Nat. Biotechnol. (1999) 17(6):551-554.
   PubMed Web of Science ®Google Scholar
• GOLDFARB DS, GARIEPY J, SCHOOLNIK G, KORNBERG RD: Synthetic peptides as nuclear localization signals. Nature (1986) 322(6080):641-644.
   PubMed Web of Science ®Google Scholar
• TAN PH, BEUTELSPACHER SC, XUE SA et al.: Modulation of human dendritic-cell function following transduction with viral vectors: implications for gene therapy. Blood (2005) 105(10):3824-3832.
   PubMed Web of Science ®Google Scholar
• TAN PH, XUE SA, MANUNTA M et al.: Effect of vectors on human endothelial cell signal transduction: implications for cardiovascular gene therapy. Arterioscler. Thromb. Vasc. Biol. (2006) 26(3):462-467.
   PubMed Web of Science ®Google Scholar
• HUDDE T, RAYNER SA, DE ALWIS M et al.: Adeno-associated and herpes simplex viruses as vectors for gene transfer to the corneal endothelium. Cornea (2000) 19(3):369-373.
   PubMed Web of Science ®Google Scholar
• BEUTELSPACHER SC, ARDJOMAND N, TAN PH et al.: Comparison of HIV-1 and EIAV-based lentiviral vectors in corneal transduction. Exp. Eye Res. (2005) 80(6):787-794.
   PubMed Web of Science ®Google Scholar
• TAN PH, KING WJ, CHEN D et al.: Transferrin receptor-mediated gene transfer to the corneal endothelium. Transplantation (2001) 71(4):552-560.
   PubMed Web of Science ®Google Scholar
• TAN PH, MANUNTA M, ARDJOMAND N et al.: Antibody targeted gene transfer to endothelium. J. Gene Med. (2003) 5(4):311-323.
   PubMed Web of Science ®Google Scholar
• ZELPHATI O, SZOKA FC JR: Mechanism of oligonucleotide release from cationic liposomes. Proc. Natl. Acad. Sci. USA (1996) 93(21):11493-11498.
   PubMed Web of Science ®Google Scholar
• MANUNTA M, TAN PH, SAGOO P, KASHEFI K, GEORGE AJ: Gene delivery by dendrimers operates via a cholesterol dependent pathway. Nucleic Acids Res. (2004) 32(9):2730-2739.
   PubMed Web of Science ®Google Scholar
• POPIK W, ALCE TM, AU WC: Human immunodeficiency virus type 1 uses lipid raft-colocalized CD4 and chemokine receptors for productive entry into CD4(+) T cells. J. Virol. (2002) 76(10):4709-4722.
   PubMed Web of Science ®Google Scholar
• ZENKE M, STEINLEIN P, WAGNER E et al.: Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells. Proc. Natl. Acad. Sci. USA (1990) 87(10):3655-3659.
   PubMed Web of Science ®Google Scholar
• COTTEN M, SALTIK M, KURSA M et al.: Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid. Virology (1994) 205(1):254-261.
   PubMed Web of Science ®Google Scholar
• CRISTIANO RJ, SMITH LC, WOO SL: Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes. Proc. Natl. Acad. Sci. USA (1993) 90(6):2122-2126.
   PubMed Web of Science ®Google Scholar
• GOTTSCHALK S, CRISTIANO RJ, SMITH LC, WOO SL: Folate receptor mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression. Gene Ther. (1994) 1(3):185-191.
   PubMed Web of Science ®Google Scholar
• ARANCIBIA-CARCAMO CV, ORAL HB, HASKARD DO, LARKIN DF, GEORGE AJ: Lipoadenofection-mediated gene delivery to the corneal endothelium: prospects for modulating graft rejection. Transplantation (1998) 65(1):62-67.
   PubMed Web of Science ®Google Scholar
• MICHAEL SI, HUANG CH, ROMER MU et al.: Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway. J. Biol. Chem. (1993) 268(10):6866-6869.
   PubMed Web of Science ®Google Scholar
• UHEREK C, FOMINAYA J, WELS W: A modular DNA carrier protein based on the structure of diphtheria toxin mediates target cell-specific gene delivery. J. Biol. Chem. (1998) 273(15):8835-8841.
   PubMed Web of Science ®Google Scholar
• MAHATO RI: Non-viral peptide-based approaches to gene delivery. J. Drug Target. (1999) 7(4):249-268.
   PubMed Web of Science ®Google Scholar
• CARR CM, KIM PS: A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell (1993) 73(4):823-832.
   PubMed Web of Science ®Google Scholar
• WAGNER E, ZATLOUKAL K, COTTEN M et al.: Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. Proc. Natl. Acad. Sci. USA (1992) 89(13):6099-6103.
   PubMed Web of Science ®Google Scholar
• DESHPANDE D, TOLEDO-VELASQUEZ D, THAKKAR D, LIANG W, ROJANASAKUL Y: Enhanced cellular uptake of oligonucleotides by EGF receptor-mediated endocytosis in A549 cells. Pharm. Res. (1996) 13(1):57-61.
   PubMed Web of Science ®Google Scholar
• PLANK C, ZATLOUKAL K, COTTEN M, MECHTLER K, WAGNER E: Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. Bioconjug. Chem. (1992) 3(6):533-539.
   PubMed Web of Science ®Google Scholar
• MIDOUX P, MENDES C, LEGRAND A et al.: Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells. Nucleic Acids Res. (1993) 21(4):871-878.
   PubMed Web of Science ®Google Scholar
• PARENTE RA, NIR S, SZOKA FC JR: pH-dependent fusion of phosphatidylcholine small vesicles. Induction by a synthetic amphipathic peptide. J. Biol. Chem. (1988) 263(10):4724-4730.
   PubMed Web of Science ®Google Scholar
• WYMAN TB, NICOL F, ZELPHATI O et al.: Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry (1997) 36(10):3008-3017.
   PubMed Web of Science ®Google Scholar
• WOLFERT MA, SEYMOUR LW: Chloroquine and amphipathic peptide helices show synergistic transfection in vitro. Gene Ther. (1998) 5(3):409-414.
   PubMed Web of Science ®Google Scholar
• MOLLENHAUER HH, MORRE DJ, ROWE LD: Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity. Biochim. Biophys. Acta (1990) 1031(2):225-246.
   PubMed Web of Science ®Google Scholar
• ROSENKRANZ AA, YACHMENEV SV, JANS DA et al.: Receptor-mediated endocytosis and nuclear transport of a transfecting DNA construct. Exp. Cell Res. (1992) 199(2):323-329.
   PubMed Web of Science ®Google Scholar
• ZAUNER W, KICHLER A, SCHMIDT W, SINSKI A, WAGNER E: Glycerol enhancement of ligand-polylysine/DNA transfection. Biotechniques (1996) 20(5):905-913.
   PubMed Web of Science ®Google Scholar
• FAJAC I, ALLO JC, SOUIL E et al.: Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells. J. Gene Med. (2000) 2(5):368-378.
   PubMed Web of Science ®Google Scholar
• HOGSET A, PRASMICKAITE L, TJELLE TE, BERG K: Photochemical transfection: a new technology for light-induced, site- directed gene delivery. Hum. Gene Ther. (2000) 11(6):869-880.
   PubMed Web of Science ®Google Scholar
• KATAYOSE S, KATAOKA K: Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer. Bioconjug. Chem. (1997) 8(5):702-707.
   PubMed Web of Science ®Google Scholar
• XU B, WIEHLE S, ROTH JA, CRISTIANO RJ: The contribution of poly-L-lysine, epidermal growth factor and streptavidin to EGF/PLL/DNA polyplex formation. Gene Ther. (1998) 5(9):1235-1243.
   PubMed Web of Science ®Google Scholar
• ROSS GF, BRUNO MD, UYEDA M et al.: Enhanced reporter gene expression in cells transfected in the presence of DMI-2, an acid nuclease inhibitor. Gene Ther. (1998) 5(9):1244-1250.
   PubMed Web of Science ®Google Scholar
• KALDERON D, RICHARDSON WD, MARKHAM AF, SMITH AE: Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature (1984) 311(5981):33-38.
   PubMed Web of Science ®Google Scholar
• BRANDEN LJ, MOHAMED AJ, SMITH CI: A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat. Biotechnol. (1999) 17(8):784-787.
   PubMed Web of Science ®Google Scholar
• ZIEMIENOWICZ A, GORLICH D, LANKA E, HOHN B, ROSSI L: Import of DNA into mammalian nuclei by proteins originating from a plant pathogenic bacterium. Proc. Natl. Acad. Sci. USA (1999) 96(7):3729-3733.
   PubMed Web of Science ®Google Scholar
• YANT SR, MEUSE L, CHIU W et al.: Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system. Nat. Genet. (2000) 25(1):35-41.
   PubMed Web of Science ®Google Scholar
• ORTIZ-URDA S, LIN Q, YANT SR et al.: Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer. Gene Ther. (2003) 10(13):1099-1104.
   PubMed Web of Science ®Google Scholar
• OLIVARES EC, HOLLIS RP, CHALBERG TW et al.: Site-specific genomic integration produces therapeutic Factor IX levels in mice. Nat. Biotechnol. (2002) 20(11):1124-1128.
   PubMed Web of Science ®Google Scholar
• BOSHART M, WEBER F, JAHN G et al.: A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell (1985) 41(2):521-530.
   PubMed Web of Science ®Google Scholar
• ADACHI Y, REYNOLDS PN, YAMAMOTO M et al.: Midkine promoter-based adenoviral vector gene delivery for pediatric solid tumors. Cancer Res. (2000) 60(16):4305-4310.
   PubMed Web of Science ®Google Scholar
• SHI N, ZHANG Y, ZHU C, BOADO RJ, PARDRIDGE WM: Brain-specific expression of an exogenous gene after i.v. administration. Proc. Natl. Acad. Sci. USA (2001) 98(22):12754-12759.
   PubMed Web of Science ®Google Scholar
• REYNOLDS PN, NICKLIN SA, KALIBEROVA L et al.: Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo. Nat. Biotechnol. (2001) 19(9):838-842.
   PubMed Web of Science ®Google Scholar
• MORISHITA K, JOHNSON DE, WILLIAMS LT: A novel promoter for vascular endothelial growth factor receptor (flt-1) that confers endothelial-specific gene expression. J. Biol. Chem. (1995) 270(46):27948-27953.
   PubMed Web of Science ®Google Scholar
• ALLEN TM, HANSEN C, MARTIN F, REDEMANN C, YAU-YOUNG A: Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo. Biochim. Biophys. Acta (1991) 1066(1):29-36.
   PubMed Web of Science ®Google Scholar
• OGRIS M, BRUNNER S, SCHULLER S, KIRCHEIS R, WAGNER E: PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. (1999) 6(4):595-605.
   PubMed Web of Science ®Google Scholar
• JONES DH, CORRIS S, MCDONALD S, CLEGG JC, FARRAR GH: Poly(DL-lactide-co-glycolide)-encapsulated plasmid DNA elicits systemic and mucosal antibody responses to encoded protein after oral administration. Vaccine (1997) 15(8):814-817.
   PubMed Web of Science ®Google Scholar
• LUO D, WOODROW-MUMFORD K, BELCHEVA N, SALTZMAN WM: Controlled DNA delivery systems. Pharm. Res. (1999) 16(8):1300-1308.
   PubMed Web of Science ®Google Scholar
• FELGNER PL, RINGOLD GM: Cationic liposome-mediated transfection. Nature (1989) 337(6205):387-388.
   PubMed Web of Science ®Google Scholar
• MORRAL N, O’NEAL W, RICE K et al.: Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons. Proc. Natl. Acad. Sci. USA (1999) 96(22):12816-12821.
   PubMed Web of Science ®Google Scholar