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Review

Gene and cell therapy for chronic ischaemic heart disease

Pages 5-15 | Published online: 06 Dec 2006

Bibliography

  • GOLDBERG RJ, KONSTAM MA: Assessing the population burden from heart failure: need for sentinel population-based surveillance systems. Arch. Intern. Med. (1999) 159(1):15-17.
  • GIBBONS RJ, ABRAMS J, CHATTERJEE K et al.: ACC/AHA 2002 guideline update for the management of patients with chronic stable angina-summary article: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on the Management of Patients With Chronic Stable Angina). J. Am. Coll. Cardiol. (2003) 41(1):159-168.
  • YANG EH, BARSNESS GW, GERSH BJ, CHANDRASEKARAN K, LERMAN A: Current and future treatment strategies for refractory angina. Mayo Clin. Proc. (2004) 79(10):1284-1292.
  • ISNER JM, PIECZEK A, SCHAINFELD R et al.: Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb. Lancet (1996) 348(9024):370-374.
  • HUGHES GC, BISWAS SS, YIN B et al.: Therapeutic angiogenesis in chronically ischemic porcine myocardium: comparative effects of bFGF and VEGF. Ann. Thorac. Surg. (2004) 77(3):812-818.
  • HERMONAT PL, MEHTA JL: Potential of gene therapy for myocardial ischemia. Curr. Opin. Cardiol. (2004) 19(5):517-523.
  • TANGIRALA RK, TSUKAMOTO K, CHUN SH et al.: Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice. Circulation (1999) 100(17):1816-1822.
  • MELO LG, AGRAWAL R, ZHANG L et al.: Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene. Circulation (2002) 105(5):602-607.
  • ABUNASRA HJ, SMOLENSKI RT, YAP J et al.: Multigene adenoviral therapy for the attenuation of ischemia-reperfusion injury after preservation for cardiac transplantation. J. Thorac. Cardiovasc. Surg. (2003) 125(5):998-1006.
  • CHEN H, ZHANG YC, LI D et al.: Protection against myocardial dysfunction induced by global ischemia-reperfusion by antisense-oligodeoxynucleotides directed at beta(1)-adrenoceptor mRNA. J. Pharmacol. Exp. Ther. (2000) 294(2):722-727.
  • LOSORDO DW, VALE PR, SYMES JF et al.: Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation (1998) 98(25):2800-2804.
  • ROSENGART TK, LEE LY, PATEL SR et al.: Angiogenesis gene therapy: Phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation (1999) 100(5):468-474.
  • VALE PR, LOSORDO DW, MILLIKEN CE et al.: Randomized, single-blind, placebo-controlled pilot study of catheter-based myocardial gene transfer for therapeutic angiogenesis using left ventricular electromechanical mapping in patients with chronic myocardial ischemia. Circulation (2001) 103(17):2138-2143.
  • LAHAM RJ, SELLKE FW, EDELMAN ER et al.: Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a Phase I randomized, double-blind, placebo-controlled trial. Circulation (1999) 100(18):1865-1871.
  • UDELSON JE, DILSIZIAN V, LAHAM RJ et al.: Therapeutic angiogenesis with recombinant fibroblast growth factor-2 improves stress and rest myocardial perfusion abnormalities in patients with severe symptomatic chronic coronary artery disease. Circulation (2000) 102(14):1605-1610.
  • LOSORDO DW, VALE PR, HENDEL RC et al.: Phase I/2 placebo-controlled, double-blind, dose-escalating trial of myocardial vascular endothelial growth factor 2 gene transfer by catheter delivery in patients with chronic myocardial ischemia. Circulation (2002) 105(17):2012-2018.
  • FORTUIN FD, VALE P, LOSORDO DW et al.: One-year follow-up of direct myocardial gene transfer of vascular endothelial growth factor-2 using naked plasmid deoxyribonucleic acid by way of thoracotomy in no-option patients. Am. J. Cardiol. (2003) 92(4):436-439.
  • SYMES JF, LOSORDO DW, VALE PR et al.: Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease. Ann. Thorac. Surg. (1999) 68(3):830-836; discussion 836-837.
  • VALE PR, LOSORDO DW, MILLIKEN CE et al.: Left ventricular electromechanical mapping to assess efficacy of phVEGF(165) gene transfer for therapeutic angiogenesis in chronic myocardial ischemia. Circulation (2000) 102(9):965-974.
  • GRINES CL, WATKINS MW, HELMER G et al.: Angiogenic Gene Therapy (AGENT) trial in patients with stable angina pectoris. Circulation (2002) 105(11):1291-1297.
  • GRINES CL, WATKINS MW, MAHMARIAN JJ et al.: A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina. J. Am. Coll. Cardiol. (2003) 42(8):1339-1347.
  • GRINES C, RUBANYI GM, KLEIMAN NS, MARROTT P, WATKINS MW: Angiogenic gene therapy with adenovirus 5 fibroblast growth factor-4 (Ad5FGF-4): a new option for the treatment of coronary artery disease. Am. J. Cardiol. (2003) 92(9B):24N-31N.
  • HENRY TD, ANNEX BH, MCKENDALL GR et al.: The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation (2003) 107(10):1359-1365.
  • KEHAT I, KENYAGIN-KARSENTI D, SNIR M et al.: Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J. Clin. Invest. (2001) 108(3):407-414.
  • XU C, POLICE S, RAO N, CARPENTER MK: Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells. Circ. Res. (2002) 91(6):501-508.
  • YANG Y, MIN JY, RANA JS et al.: VEGF enhances functional improvement of postinfarcted hearts by transplantation of ESC-differentiated cells. J. Appl. Physiol. (2002) 93(3):1140-1151.
  • BEHFAR A, ZINGMAN LV, HODGSON DM et al.: Stem cell differentiation requires a paracrine pathway in the heart. FASEB J. (2002) 16(12):1558-1566.
  • THOMSON JA, ITSKOVITZ-ELDOR J, SHAPIRO SS et al.: Embryonic stem cell lines derived from human blastocysts. Science (1998) 282(5391):1145-1147.
  • FISCHBACH GD, FISCHBACH RL: Stem cells: science, policy, and ethics. J. Clin. Invest. (2004) 114(10):1364-1370.
  • WEISSMAN IL: Stem cells-scientific, medical, and political issues. N. Engl. J. Med. (2002) 346(20):1576-1579.
  • MURRY CE, WISEMAN RW, SCHWARTZ SM, HAUSCHKA SD: Skeletal myoblast transplantation for repair of myocardial necrosis. J. Clin. Invest. (1996) 98(11):2512-2523.
  • TAYLOR DA, ATKINS BZ, HUNGSPREUGS P et al.: Regenerating functional myocardium: improved performance after skeletal myoblast transplantation. Nat. Med. (1998) 4(8):929-933.
  • LEOBON B, GARCIN I, MENASCHE P et al.: Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host. Proc. Natl. Acad. Sci. USA (2003) 100(13):7808-7811.
  • REINECKE H, POPPA V, MURRY CE: Skeletal muscle stem cells do not transdifferentiate into cardiomyocytes after cardiac grafting. J. Mol. Cell. Cardiol. (2002) 34(2):241-249.
  • JAIN M, DERSIMONIAN H, BRENNER DA et al.: Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation (2001) 103(14):1920-1927.
  • MENASCHE P, HAGEGE AA, VILQUIN JT et al.: Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction. J. Am. Coll. Cardiol. (2003) 41(7):1078-1083.
  • HERREROS J, PROSPER F, PEREZ A et al.: Autologous intramyocardial injection of cultured skeletal muscle-derived stem cells in patients with non-acute myocardial infarction. Eur. Heart J. (2003) 24(22):2012-2020.
  • SIMINIAK T, KALAWSKI R, FISZER D et al.: Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: Phase I clinical study with 12 months of follow-up. Am. Heart J. (2004) 148(3):531-537.
  • PERIN EC, DOHMANN HF, BOROJEVIC R et al.: Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation (2003) 107(18):2294-2302.
  • STAMM C, KLEINE HD, WESTPHAL B et al.: CABG and bone marrow stem cell transplantation after myocardial infarction. Thorac. Cardiovasc. Surg. (2004) 52(3):152-158.
  • POH KK, HOFFMEISTER P, SHTURMAN L et al.: Is stem cell therapy arrhythmogenic? Initial results from a Phase I multi-center clinical trial of intramyocardial autologous CD34-positive cell transfer. Circulation (2005) 112(17 Suppl.):138.
  • LI J, PATEL VV, KOSTETSKII I et al.: Cardiac-specific loss of N-cadherin leads to alteration in connexins with conduction slowing and arrhythmogenesis. Circ. Res. (2005) 97(5):474-481.
  • ABRAHAM MR, HENRIKSON CA, TUNG L et al.: Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation. Circ. Res. (2005) 97(2):159-167.
  • CHANG MG, TUNG L, SEKAR RB et al.: Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model. Circulation (2006) 113(15):1832-1841.
  • CHACHQUES JC, HERREROS J, TRAININI J et al.: Autologous human serum for cell culture avoids the implantation of cardioverter-defibrillators in cellular cardiomyoplasty. Int. J. Cardiol. (2004) 95(Suppl. 1):S29-S33.
  • HIERLIHY AM, SEALE P, LOBE CG, RUDNICKI MA, MEGENEY LA: The post-natal heart contains a myocardial stem cell population. FEBS Lett. (2002) 530(1-3):239-243.
  • OH H, BRADFUTE SB, GALLARDO TD et al.: Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc. Natl. Acad. Sci. USA (2003) 100(21):12313-12318.
  • LAUGWITZ KL, MORETTI A, LAM J et al.: Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages. Nature (2005) 433(7026):647-653.
  • MUMMERY CL: Cardiology: solace for the broken-hearted? Nature (2005) 433(7026):585-587.
  • CLARKE DL, JOHANSSON CB, WILBERTZ J et al.: Generalized potential of adult neural stem cells. Science (2000) 288(5471):1660-1663.
  • MALOUF NN, COLEMAN WB, GRISHAM JW et al.: Adult-derived stem cells from the liver become myocytes in the heart in vivo. Am. J. Pathol. (2001) 158(6):1929-1935.
  • ASAHARA T, MUROHARA T, SULLIVAN A et al.: Isolation of putative progenitor endothelial cells for angiogenesis. Science (1997) 275(5302):964-967.
  • BADORFF C, BRANDES RP, POPP R et al.: Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes. Circulation (2003) 107(7):1024-1032.
  • JIANG Y, JAHAGIRDAR BN, REINHARDT RL et al.: Pluripotency of mesenchymal stem cells derived from adult marrow. Nature (2002) 418(6893):41-49.
  • WEISSMAN IL: Stem cells: units of development, units of regeneration, and units in evolution. Cell (2000) 100(1):157-168.
  • MAKINO S, FUKUDA K, MIYOSHI S et al.: Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. (1999) 103(5):697-705.
  • ORLIC D, KAJSTURA J, CHIMENTI S et al.: Bone marrow stem cells regenerate infarcted myocardium. Pediatr. Transplant. (2003) 7(Suppl. 3):86-88.
  • JACKSON KA, MAJKA SM, WANG H et al.: Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J. Clin. Invest. (2001) 107(11):1395-1402.
  • QUAINI F, URBANEK K, BELTRAMI AP et al.: Chimerism of the transplanted heart. N. Engl. J. Med. (2002) 346(1):5-15.
  • MULLER P, PFEIFFER P, KOGLIN J et al.: Cardiomyocytes of noncardiac origin in myocardial biopsies of human transplanted hearts. Circulation (2002) 106(1):31-35.
  • LAFLAMME MA, MYERSON D, SAFFITZ JE, MURRY CE: Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts. Circ. Res. (2002) 90(6):634-640.
  • GLASER R, LU MM, NARULA N, EPSTEIN JA: Smooth muscle cells, but not myocytes, of host origin in transplanted human hearts. Circulation (2002) 106(1):17-19.
  • DEB A, WANG S, SKELDING KA et al.: Bone marrow-derived cardiomyocytes are present in adult human heart: a study of gender-mismatched bone marrow transplantation patients. Circulation (2003) 107(9):1247-1249.
  • TERADA N, HAMAZAKI T, OKA M et al.: Bone marrow cells adopt the phenotype of other cells by spontaneous cell fusion. Nature (2002) 416(6880):542-545.
  • YING QL, NICHOLS J, EVANS EP, SMITH AG: Changing potency by spontaneous fusion. Nature (2002) 416(6880):545-548.
  • VASSILOPOULOS G, WANG PR, RUSSELL DW: Transplanted bone marrow regenerates liver by cell fusion. Nature (2003) 422(6934):901-904.
  • WANG X, WILLENBRING H, AKKARI Y et al.: Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature (2003) 422(6934):897-901.
  • PERIN EC, SILVA GV: Stem cell therapy for cardiac diseases. Curr. Opin. Hematol. (2004) 11(6):399-403.
  • GOODELL MA: Stem-cell ‘plasticity’: befuddled by the muddle. Curr. Opin. Hematol. (2003) 10(3):208-213.
  • MURRY CE, SOONPAA MH, REINECKE H et al.: Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature (2004) 428(6983):664-668.
  • WOLLERT KC, DREXLER H: Clinical applications of stem cells for the heart. Circ. Res. (2005) 96(2):151-163.
  • TEPPER OM, CAPLA JM, GALIANO RD et al.: Adult vasculogenesis occurs through in situ recruitment, proliferation, and tubulization of circulating bone marrow-derived cells. Blood (2005) 105(3):1068-1077.
  • YOON YS, WECKER A, HEYD L et al.: Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. J. Clin. Invest. (2005) 115(2):326-338.
  • NYGREN JM, JOVINGE S, BREITBACH M et al.: Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat. Med. (2004) 10(5):494-501.
  • KINNAIRD T, STABILE E, BURNETT MS et al.: Marrow-derived stromal cells express genes encoding a broad spectrum of arteriogenic cytokines and promote in vitro and in vivo arteriogenesis through paracrine mechanisms. Circ. Res. (2004) 94(5):678-685.
  • SHAKE JG, GRUBER PJ, BAUMGARTNER WA et al.: Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects. Ann. Thorac. Surg. (2002) 73(6):1919-1925; discussion 1926.
  • MANGI AA, NOISEUX N, KONG D et al.: Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat. Med. (2003) 9(9):1195-1201.
  • AMADO LC, SALIARIS AP, SCHULERI KH et al.: Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc. Natl. Acad. Sci. USA (2005) 102(32):11474-11479.
  • TSE WT, PENDLETON JD, BEYER WM, EGALKA MC, GUINAN EC: Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation (2003) 75(3):389-397.
  • POH KK, SPERRY E, YOUNG RG et al.: Repeated direct endomyocardial transplantation of allogeneic mesenchymal stem cells: Safety of a high dose, ‘off-the-shelf’, cellular cardiomyoplasty strategy. Int. J. Cardiol. (2006) (In Press).
  • ORLIC D, KAJSTURA J, CHIMENTI S et al.: Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc. Natl. Acad. Sci. USA (2001) 98(18):10344-10349.
  • SCHMEISSER A, GARLICHS CD, ZHANG H et al.: Monocytes coexpress endothelial and macrophagocytic lineage markers and form cord-like structures in Matrigel under angiogenic conditions. Cardiovasc. Res. (2001) 49(3):671-680.
  • ASAHARA T, KAWAMOTO A: Endothelial progenitor cells for postnatal vasculogenesis. Am. J. Physiol. Cell Physiol. (2004) 287(3):C572-C579.
  • KAWAMOTO A, GWON HC, IWAGURO H et al.: Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia. Circulation (2001) 103(5):634-637.
  • KOCHER AA, SCHUSTER MD, SZABOLCS MJ et al.: Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat. Med. (2001) 7(4):430-436.
  • IWASAKI H, KAWAMOTO A, ISHIKAWA M et al.: Dose-dependent contribution of CD34-positive cell transplantation to concurrent vasculogenesis and cardiomyogenesis for functional regenerative recovery after myocardial infarction. Circulation (2006) 113(10):1311-1325.
  • STRAUER BE, BREHM M, ZEUS T et al.: Repair of infarcted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans. Circulation (2002) 106(15):1913-1918.
  • ASSMUS B, SCHACHINGER V, TEUPE C et al.: Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI). Circulation (2002) 106(24):3009-3017.
  • WOLLERT KC, MEYER GP, LOTZ J et al.: Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet (2004) 364(9429):141-148.
  • HAMANO K, NISHIDA M, HIRATA K et al.: Local implantation of autologous bone marrow cells for therapeutic angiogenesis in patients with ischemic heart disease: clinical trial and preliminary results. Jpn. Circ. J. (2001) 65(9):845-847.
  • FUCHS S, SATLER LF, KORNOWSKI R et al.: Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study. J. Am. Coll. Cardiol. (2003) 41(10):1721-1724.
  • TSE HF, KWONG YL, CHAN JK et al.: Angiogenesis in ischaemic myocardium by intramyocardial autologous bone marrow mononuclear cell implantation. Lancet (2003) 361(9351):47-49.
  • STAMM C, WESTPHAL B, KLEINE HD et al.: Autologous bone-marrow stem-cell transplantation for myocardial regeneration. Lancet (2003) 361(9351):45-46.
  • YOON YS, PARK JS, TKEBUCHAVA T, LUEDEMAN C, LOSORDO DW: Unexpected severe calcification after transplantation of bone marrow cells in acute myocardial infarction. Circulation (2004) 109(25):3154-3157.
  • LUNDE K, SOLHEIM S, AAKHUS S et al.: Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N. Engl. J. Med. (2006) 355(12):1199-1209.
  • SCHACHINGER V, ERBS S, ELSASSER A et al.: Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N. Engl. J. Med. (2006) 355(12):1210-1221.
  • SCHACHINGER V, ASSMUS B, BRITTEN MB et al.: Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial. J. Am. Coll. Cardiol. (2004) 44(8):1690-1699.
  • ASSMUS B, HONOLD J, SCHACHINGER V et al.: Transcoronary transplantation of progenitor cells after myocardial infarction. N. Engl. J. Med. (2006) 355(12):1222-1232.
  • ROSENZWEIG A: Cardiac cell therapy-mixed results from mixed cells. N. Engl. J. Med. (2006) 355(12):1274-1277.
  • HAO X, MANSSON-BROBERG A, GUSTAFSSON T et al.: Angiogenic effects of dual gene transfer of bFGF and PDGF-BB after myocardial infarction. Biochem. Biophys. Res. Commun. (2004) 315(4):1058-1063.
  • SHYU KG, WANG MT, WANG BW et al.: Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc. Res. (2002) 54(3):576-583.
  • TANG YL, QIAN K, ZHANG YC, SHEN L, PHILLIPS MI: Mobilizing of haematopoietic stem cells to ischemic myocardium by plasmid mediated stromal-cell-derived factor-1alpha (SDF-1alpha) treatment. Regul. Pept. (2005) 125(1-3):1-8.
  • KAWAMOTO A, MURAYAMA T, KUSANO K et al.: Synergistic effect of bone marrow mobilization and vascular endothelial growth factor-2 gene therapy in myocardial ischemia. Circulation (2004) 110(11):1398-1405.
  • SUZUKI K, MURTUZA B, SMOLENSKI RT et al.: Cell transplantation for the treatment of acute myocardial infarction using vascular endothelial growth factor-expressing skeletal myoblasts. Circulation (2001) 104(12 Suppl. 1):I207-I212.
  • NIAGARA MI, HAIDER H, YE L et al.: Autologous skeletal myoblasts transduced with a new adenoviral bicistronic vector for treatment of hind limb ischemia. J. Vasc. Surg. (2004) 40(4):774-785.
  • CUEVAS P, CARCELLER F, ORTEGA S et al.: Hypotensive activity of fibroblast growth factor. Science (1991) 254(5035):1208-1210.
  • PITTENGER MF, MARTIN BJ: Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. (2004) 95(1):9-20.
  • SHINTANI S, MUROHARA T, IKEDA H et al.: Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation (2001) 103(23):2776-2779.
  • YEH ET, ZHANG S, WU HD et al.: Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation (2003) 108(17):2070-2073.
  • AICHER A, BRENNER W, ZUHAYRA M et al.: Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation (2003) 107(16):2134-2139.
  • OHTSUKA M, TAKANO H, ZOU Y et al.: Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization. FASEB J. (2004) 18(7):851-853.
  • MINATOGUCHI S, TAKEMURA G, CHEN XH et al.: Acceleration of the healing process and myocardial regeneration may be important as a mechanism of improvement of cardiac function and remodeling by postinfarction granulocyte colony-stimulating factor treatment. Circulation (2004) 109(21):2572-2580.
  • MAEKAWA Y, ANZAI T, YOSHIKAWA T et al.: Effect of granulocyte-macrophage colony-stimulating factor inducer on left ventricular remodeling after acute myocardial infarction. J. Am. Coll. Cardiol. (2004) 44(7):1510-1520.
  • HILL JM, SYED MA, ARAI AE et al.: Outcomes of granulocyte colony-stimulating factor administration to patients with severe coronary artery disease. Circulation (2004) 110(Suppl. III):352.
  • SEILER C, POHL T, WUSTMANN K et al.: Promotion of collateral growth by granulocyte-macrophage colony-stimulating factor in patients with coronary artery disease: a randomized, double-blind, placebo-controlled study. Circulation (2001) 104(17):2012-2017.
  • LEW WY: Mobilizing cells to the injured myocardium: a novel rescue strategy or an unwelcome intrusion? J. Am. Coll. Cardiol. (2004) 44(7):1521-1522.
  • KANG HJ, KIM HS, ZHANG SY et al.: Effects of intracoronary infusion of peripheral blood stem-cells mobilised with granulocyte-colony stimulating factor on left ventricular systolic function and restenosis after coronary stenting in myocardial infarction: the MAGIC cell randomised clinical trial. Lancet (2004) 363(9411):751-756.
  • LOPEZ JJ, LAHAM RJ, CARROZZA JP et al.: Hemodynamic effects of intracoronary VEGF delivery: evidence of tachyphylaxis and NO dependence of response. Am. J. Physiol. (1997) 273(3 Pt 2):H1317-H1323.
  • VULLIET PR, GREELEY M, HALLORAN SM, MACDONALD KA, KITTLESON MD: Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs. Lancet (2004) 363(9411):783-784.
  • THOMPSON CA, NASSERI BA, MAKOWER J et al.: Percutaneous transvenous cellular cardiomyoplasty. A novel nonsurgical approach for myocardial cell transplantation. J. Am. Coll. Cardiol. (2003) 41(11):1964-1971.
  • SIMONS M, BONOW RO, CHRONOS NA et al.: Clinical trials in coronary angiogenesis: issues, problems, consensus: an expert panel summary. Circulation (2000) 102(11):E73-E86.
  • PARISI AF, FOLLAND ED, HARTIGAN P: A comparison of angioplasty with medical therapy in the treatment of single-vessel coronary artery disease. Veterans Affairs ACME Investigators. N. Engl. J. Med. (1992) 326(1):10-16.
  • WELT FG, LOSORDO DW: Cell therapy for acute myocardial infarction: curb your enthusiasm? Circulation (2006) 113(10):1272-1274.
  • MEOLI DF, SADEGHI MM, KRASSILNIKOVA S et al.: Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction. J. Clin. Invest. (2004) 113(12):1684-1691.
  • ASAHARA T, MASUDA H, TAKAHASHI T et al.: Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ. Res. (1999) 85(3):221-228.
  • VILLANUEVA FS, ABRAHAM JA, SCHREINER GF et al.: Myocardial contrast echocardiography can be used to assess the microvascular response to vascular endothelial growth factor-121. Circulation (2002) 105(6):759-765.
  • PEARLMAN JD, HIBBERD MG, CHUANG ML et al.: Magnetic resonance mapping demonstrates benefits of VEGF-induced myocardial angiogenesis. Nat. Med. (1995) 1(10):1085-1089.
  • PEARLMAN JD, LAHAM RJ, POST M, LEINER T, SIMONS M: Medical imaging techniques in the evaluation of strategies for therapeutic angiogenesis. Curr. Pharm. Des. (2002) 8(16):1467-1496.
  • SAEED M, SALONER D, WEBER O et al.: MRI in guiding and assessing intramyocardial therapy. Eur. Radiol. (2005) 15(5):851-863.
  • MCDONALD DM, CHOYKE PL: Imaging of angiogenesis: from microscope to clinic. Nat. Med. (2003) 9(6):713-725.
  • HEPPNER P, LINDNER JR: Contrast ultrasound assessment of angiogenesis by perfusion and molecular imaging. Expert Rev. Mol. Diagn. (2005) 5(3):447-455.
  • LEONG-POI H, CHRISTIANSEN J, HEPPNER P et al.: Assessment of endogenous and therapeutic arteriogenesis by contrast ultrasound molecular imaging of integrin expression. Circulation (2005) 111(24):3248-3254.
  • FUJII H, TOMITA S, NAKATANI T et al.: A novel application of myocardial contrast echocardiography to evaluate angiogenesis by autologous bone marrow cell transplantation in chronic ischemic pig model. J. Am. Coll. Cardiol. (2004) 43(7):1299-1305.
  • BULTE JW, KRAITCHMAN DL: Monitoring cell therapy using iron oxide MR contrast agents. Curr. Pharm. Biotechnol. (2004) 5(6):567-584.

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