A20 is overexpressed in glioma cells and may serve as a potential therapeutic target

Bibliography

• Opipari AW Jr, Boguski MS, Dixit VM. The A20 cDNA induced by tumor necrosis factor α encodes a novel type of zinc finger protein. J Biol Chem 1990;265(25):14705-8
   PubMed Web of Science ®Google Scholar
• Opipari AW Jr, Hu HM, Yabkowitz R, et al. The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity. J Biol Chem 1992;267(18):12424-7
   PubMed Web of Science ®Google Scholar
• Ferran C, Stroka DM, Badrichani AZ, et al. A20 inhibits NF-κB activation in endothelial cells without sensitizing to tumor necrosis factor-mediated apoptosis. Blood 1998;91:2249-58
   PubMed Web of Science ®Google Scholar
• Heyninck K, De Valck D, Vanden Berghe W, et al. The zinc finger protein A20 inhibits TNF-induced NF-κB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-κB inhibiting protein ABIN. J Cell Biol 1999;145:1471-82
   PubMedGoogle Scholar
• Jaattela M, Mouritzen H, Elling F, et al. A20 zinc finger protein inhibits TNF and IL-1 signaling. J Immunol 1996;156(3):1166-73
   PubMed Web of Science ®Google Scholar
• Sarma V, Lin Z, Clark L, et al. Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis. J Biol Chem 1995;270(21):12343-6
   PubMed Web of Science ®Google Scholar
• Arvelo MB, Cooper JT, Longo C, et al. A20 protects mice from galactosmine/lipopolysaccharide acute toxic lethal hepatitis. Hepatology 2002;35:535-43
   PubMed Web of Science ®Google Scholar
• Grey ST, Arvelo MB, Hasenkamp W, et al. A20 inhibits cytokine-induced apoptosis and nuclear factor κB-dependent gene activation in islets. J Exp Med 1999;190:1135-46
   PubMed Web of Science ®Google Scholar
• Malewicz M, Zeller N, Yilmaz ZB, et al. NF-κB controls the balance between Fas and tumor necrosis factor cell death pathways during T cell receptor-induced apoptosis via the expression of its target gene A20. J Biol Chem 2003;278(35):32825-33
   PubMed Web of Science ®Google Scholar
• Beyaert R, Heyninck K, van Huffel S. A20 and A20-binding proteins as cellular inhibitors of nuclear factor-κB-dependent gene expression and apoptosis. Biochem Pharmacol 2000;60(8):1143-51
   PubMed Web of Science ®Google Scholar
• Mattson MP, Meffert MK. Roles for NF-κB in nerve cell survival, plasticity, and disease. Cell Death Differ 2006;13(5):852-60
   PubMed Web of Science ®Google Scholar
• Conti A, Ageunnouz M, La Toree D, et al. Expression of the tumor necrosis factor receptor-associated factors 1 and 2 and regulation of the nuclear factor-κB antiapoptotic activity in human gliomas. J Neurosurg 2005;103(5):873-81
   PubMedGoogle Scholar
• Gonzales M. The 2000 World Health Organization classification of tumours of the nervous system. J Clin Neurosci 2001;8(1):1-3
   PubMed Web of Science ®Google Scholar
• Souza AI, Felkin LE, Mccormack AM, et al. Sequential expression of three known protective genes in cardiac biopsies after transplantation. Transplantation 2005;79(5):584-90
   PubMedGoogle Scholar
• Wissing D, Mouritzen H, Jaattela M. TNF-induced mitochondrial changes and activation of apoptotic proteases are inhibited by A20. Free Radic Biol Med 1998;25(1):57-65
   PubMed Web of Science ®Google Scholar
• Onose A, Hashimoto S, Hayashi S, et al. An inhibitory effect of A20 on NF-κB activation in airway epithelium upon influenza virus infection. Eur J Pharmacol 2006;541(3):198-204
   PubMedGoogle Scholar
• Wertz IE, O'Rourke KM, Zhou HL, et al. De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling. Nature 2004;430:694-9
   PubMed Web of Science ®Google Scholar
• Klinkenberg M, Van Huffel S, Heyninck K, et al. Functional redundancy of the zinc fingers of A20 for inhibition of NF-κB activation and protein-protein interactions. FEBS Lett 2001;498(1):93-7
   PubMedGoogle Scholar
• Lee EG, Boone DL, Chai S, et al. Failure to regulate TNF-induced NF-κB and cell death responses in A20-deficient mice. Science 2000;289(5488):2350-4
   PubMed Web of Science ®Google Scholar
• Tewari M, Wolf FW, Seldin MF, et al. Lymphoid expression and regulation of A20, an inhibitor of programmed cell death. J Immunol 1995;154(4):1699-706
   PubMed Web of Science ®Google Scholar
• Codd JD, Salisbury JR, Packham G, et al. A20 RNA expression is associated with undifferentiated nasopharyngeal carcinoma and poorly differentiated head and neck squamous cell carcinoma. J Pathol 1999;187(5):549-55
   PubMedGoogle Scholar
• Golovko O, Nazarova N, Tuohimaa P. A20 gene expression is regulated by TNF, vitamin D and androgen in prostate cancer cells. J Steroid Biochem Mol Biol 2005;94(1-3):197-202
   PubMedGoogle Scholar
• Bredel M, Bredel C, Juric D, et al. Tumor necrosis factor α-induced protein 3 as a putative regulator of nuclear factor-κB-mediated resistance to O6-alkylating agents in human glioblastomas. J Clin Oncol 2006;24(2):274-87
   PubMed Web of Science ®Google Scholar
• Krikos A, Laherty CD, Dixit VM. Transcriptional activation of the tumor necrosis factor α-inducible zinc finger protein, A20, is mediated by NF-κB elements. J Biol Chem 1992;267:17971-6
   PubMed Web of Science ®Google Scholar
• Yamamoto M, Oshiro S, Tsugu H, et al. Treatment of recurrent malignant supratentorial astrocytomas with carboplatin and etoposide combined with recombinant mutant human tumor necrosis factor-alpha. Anticancer Res 2002;22(4):2447-53
   PubMedGoogle Scholar