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Drug Safety Evaluations

Long-term safety of tacrolimus ointment in atopic dermatitis

, MD PhD & , MD PhD
Pages 501-506 | Published online: 12 May 2009

Bibliography

  • Goto T, Kino T, Hatanaka K, et al. Discovery of FK-506, a novel immunosuppressant isolated from Sterptomyces tsukubaensis. Transpl Proc 1987;19(Suppl 6):4-8
  • Lauerma AI, Maibach HI, Granlund H, et al. Unhibition of contact allergy reaction by topical FK 506. Lancet 1992;340:556
  • Nakagawa H, Etoh T, Ishibashi Y, et al. Tacrolimus ointment for atopic dermatitis. Lancet 1994;344:883
  • Ruzicka T, Bieber T, Schöpf E, et al. A short-term trial with tacrolimus ointment for atopic dermatitis. N Engl J Med 1997;337:816-21
  • Reitamo S. Tacrolimus. A new topical immunomodulatory therapy for atopic dermatitis. J Allergy Clin Immunol 2001;107:445-8
  • Undre AN. Pharmacokinetics of tacrolimus ointment. In: Ruzicka T, Reitamo S, editors, Tacrolimus ointment, Springer, Berlin; 2004. p. 99-110
  • O'Regan GM, Sandilands A, McLean WH, et al. Filaggrin in atopic dermatitis. J Allergy Clin Immunol 2008;122:689-93
  • Howell MD, Kim BE, Gao P, et al. Cytokine modulation of atopic dermatitis filaggrin gene expression. J Allergy Clin Immunol 2007;1120:150-5
  • Rubins A, Gutmane R, Valdmane N, et al. Pharmacokinetics of 0.1% tacrolimus ointment after first and repeated application to adults with moderate to severe atopic dermatitis. J Invest Dermatol 2005;125:68-71
  • Harper J, Smith C, Rubins A, et al. A multicenter study of the pharmacokinetics of tacrolimus ointment after first and repeated application to children with atopic dermatitis. J Invest Dermatol 2005;124:695-9
  • Reitamo S, Mandelin JM, Rubins A, et al. Pharmacokinetics of tacrolimus ointment in infants of 3-24 months of age. Int J Dermatol 2009;48:348-55
  • Luger TA, Steinhoff M, Remitz A, Reitamo S. Topical calcineurin inhibitors. In: Reitamo S, Luger TA, Steinhoff M, editors, Textbook of atopic dermatitis. Informa Healthcare, London 2008. p. 221-45
  • Reitamo S, Harper J, Bos J, et al. 0.03% tacrolimus ointment applied once or twice daily is more effacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis. Br J Dermatol 2004;150:554-62
  • Reitamo S, Wollenberg A, Schöpf E, et al. Safety and efficacy of 1 year of tacrolimus ointment in adults with atopic dermatitis. Arch Dermatol 2000;136:999-1006
  • Kang S, Lucky AW, Pariser D, et al. Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. J Am Acad Dermatol 2001;44(1 Suppl):S58-64
  • Reitamo S, Ortonne JP, Sand C, et al. Long-term treatment with 0.1% tacrolimus ointment in adults with atopic dermatitis: results of a two-year, multicentre, non-comparative study. Acta Derm Venereol 2007;87:406-12
  • Remitz A, Harper J, Rustin M, et al. Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. Acta Derm Venereol 2007;87:54-61
  • Hanifin JM, Paller AS, Eichenfield L, et al. Efficacy and safety of tacrolimus ointment treatment for up to 4 years in patients with atopic dermatitis. J Am Acad Dermatol 2005;53(2 Suppl 2):S186-94
  • Reitamo S, Rustin M, Harper J, et al. A 4-year follow-up study of atopic dermatitis therapy with 0.1% tacrolimus ointment. Br J Dermatol 2008;159:942-51
  • Berth-Jones J, Damstra RJ, Golsch S, et al. Twice weekly fluticasone propionate added to emollient maintenace treatment to reduce risk of relapse in atopic dermatitis: randomized, double-blind, parallel group study. Br Med J 2003;326:1367-70
  • Wollenberg A, Reitamo S, Girolomoni G, et al. Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment. Allergy 2008;63:742-50
  • ThaÇi D, Reitamo S, Gonzalez Ensenat MA, et al. Proactive disease management with 0.03% tacrolimus ointment for children with atopic dermatitis: results of a randomized, multicentre, comparative study. Br J Dermatol 2008;159:1348-56
  • Reitamo S, Remitz A, Haahtela T. Hit early and hit hard in atopic dermatitis and not only in asthma. Allergy 2009;64:503-4
  • Breneman D, Fleischer AB Jr, Abramovits W, et al. Intermittent therapy for flare prevention and long-term disease control in stabilized atopic dermatitis: a randomized comparison of 3-times-weekly applications of tacrolimus ointment. J Am Acad Dermatol 2008;58:990-9
  • Paller AS, Eichenfield LF, Kirsner RS, et al. Three times weekly tacrolimus ointment reduces relapse in stabilized atopic dermatitis: a new paradigm for use. Pediatrics 2008;122:e1210-8
  • Reitamo S, Van Leent EJ, Ho V, et al. Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis. J Allergy Clin Immunol 2002;109:539-46
  • Reitamo S, Rustin M, Ruzicka T, et al. Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis. J Allergy Clin Immunol 2002;109:547-55
  • Doss N, Reitamo S, Dubertret L, et al. Superiority of tacrolimus 0.1% ointment compared with fluticasone 0.005% in adults with moderate to severe atopic dermatitis of the face: results from a randomized, double-blind trial. Br J Dermatol, published online April 16 2009; doi:10.1111/j.1365-2133.2009.09143x
  • Reitamo S, Ortonne JP, Sand C, et al. A multicentre, randomized, double-blind, controlled study of long-term treatment with 0.1% tacrolimus ointment in adults with moderate to severe atopic dermatitis. Br J Dermatol 2005;152:1282-9
  • Allen A, Siegfried E, Silverman R, et al. Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome. Arch Dermatol 2001;137:747-50
  • Bieber T. Atopic dermatitis. N Engl J Med 2008;358:1483-94
  • Mandelin JM, Remitz A, Virtanen HM, Reitamo S. Recall-antigen reactions in patients with atopic dermatitis treated with tacrolimus ointment for one year. J Allergy Clin Immunol 2008;121:777-9
  • Remitz A, Kyllönen H, Granlund H, Reitamo S. Tacrolimus ointment reduces staphylococcal colonization of atopic dermatitis lesions. J Allergy Clin Immunol 2001;107:196-7
  • Ständer S, Ständer H, Seeliger S, et al. Topical pimecrolimus and tacrolimus transiently induce neuropeptide release and mast cell degranulation in murine skin. Br J Dermatol 2007;156:1020-6
  • Fleischer AB Jr, Ling M, Eichenfield L, et al. Tacrolimus ointment for the treatment of atopic dermatitis is not associated with an increase in cutaneous infections. J Am Acad Dermatol 2002;47:562-70
  • Arellano FM, Wentworth CE, Arana A, et al. Risk of lymphoma following exposure to calcineurin inhibitors and topical steroids in patients with atopic dermatitis. J Invest Dermatol 2007;127:808-16
  • Reitamo S, Rissanen J, Remitz A, et al. Tacrolimus ointment does not affect collagen synthesis: results of a single-center randomized trial. J Invest Dermatol 1998;111:396-8
  • Kyllönen H, Remitz A, Mandelin JM, et al. Effects of 1-year intermittent treatment with topical tacrolimus monotherapy on skin collagen synthesis in patients with atopic dermatitis. Br J Dermatol 2004;150:1174-81
  • Sugiura H, Uehara M, Hoshino N, Yamaji A. Long-term efficacy of tacrolimus ointment for recalcitrant facial erythema resistant to topical corticosteroids in adult patients with atopic dermatitis. Arch Dermatol 2000;136:1062-3

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