Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others

Bibliography

• FDA: Facts about over-the-counter (OTC) sodium phosphate drug products. Available from: http://www.fda.gov/Drugs/DrugSafety/ucm380757.htm [Last accessed 3 January 2015]
   Google Scholar
• Beloosesky Y, Grinblat J, Weiss A, et al. Electrolyte disorders following oral sodium phosphate administration for bowel cleansing in elderly patients. Arch Intern Med 2003;163:803-8
   PubMed Web of Science ®Google Scholar
• Curran MP, Plosker GL. Oral sodium phosphate solution: a review of its use as a colorectal cleanser. Drugs 2004;64:1697-714
   PubMed Web of Science ®Google Scholar
• Portalatin M, Winstead N. Medical management of constipation. Clin Colon Rectal Surg 2012;25:12-19
   PubMedGoogle Scholar
• Lochy S, Jacobs R, Honore PM, et al. Phosphate induced crystal acute kidney injury - an under-recognized cause of acute kidney injury potentially leading to chronic kidney disease: case report and review of the literature. Int J Nephrol Renovasc Dis 2013;6:61-4
   PubMedGoogle Scholar
• Schiller LR. Clinical pharmacology and use of laxatives and lavage solutions. J Clin Gastroenterol 1999;28:11-18
   PubMed Web of Science ®Google Scholar
• Hoffmanová I, Anděl M;Serious risk related to oral use of sodium phosphate solution. Vnitr Lek 2013;59:1111-16
   PubMedGoogle Scholar
• Rex DK. Dosing considerations in the use of sodium phosphate bowel preparations for colonoscopy. Ann Pharmacother 2007;41:1466-75
   PubMed Web of Science ®Google Scholar
• Drugs.com. OsmoPrep Dosage. Available from: http://www.drugs.com/dosage/osmoprep.html [Last accessed 6 January 2015]
   Google Scholar
• Rex DK, Chasen R, Pochapin MB. Safety and efficacy of two reduced dosing regimens of sodium phosphate tablets for preparation prior to colonoscopy. Aliment Pharmacol Ther 2002;16:937-44
   PubMed Web of Science ®Google Scholar
• FDA Science Background Paper: Acute Phosphate Nephropathy and Renal Failure Associated With the Use of Oral Sodium Phosphate Bowel Cleansing Products. Available from: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm161581.htm [Last accessed 3 January 2015]
   Google Scholar
• Hurst FP, Bohen EM, Osgard EM, et al. Association of oral sodium phosphate purgative use with acute kidney injury. J Am Soc Nephrol 2007;18:3192-8
   PubMed Web of Science ®Google Scholar
• Kan W, Wang H, Chien C, et al. Intermediate bioelectrolyte changes after phospho-soda or polyethylene glycol precolonoscopic laxatives in a population undergoing health examinations. Nephrol Dial Transplant 2012;27:752-7
   PubMed Web of Science ®Google Scholar
• Heher EC, Thier SO, Rennke H, et al. Adverse renal and metabolic effects associated with oral sodium phosphate bowel preparation. Clin J Am Soc Nephrol 2008;3:1494-503
   PubMed Web of Science ®Google Scholar
• Vanner SJ, MacDonald PH, Paterson WG, et al. A randomized prospective trial comparing oral sodium phosphate with standard polyethylene glycol-based lavage solution (Golytely) in the preparation of patients for colonoscopy. Am J Gastroenterol 1990;85:422-7
   PubMed Web of Science ®Google Scholar
• Kolts BE, Lyles WE, Achem SR, et al. A comparison of the effectiveness and patient tolerance of oral sodium phosphate, castor oil, and standard electrolyte lavage for colonoscopy or sigmoidoscopy preparation. Am J Gastroenterol 1993;88:1218-23
   PubMed Web of Science ®Google Scholar
• Cohen SM, Wexner SD, Binderow SR, et al. Prospective, randomized, endoscopic-blinded trial comparing precolonoscopy bowel cleansing methods. Dis Colon Rectum 1994;37:689-96
   PubMed Web of Science ®Google Scholar
• Frommer D. Cleansing ability and tolerance of three bowel preparations for colonoscopy. Dis Colon Rectum 1997;40:100-4
   PubMed Web of Science ®Google Scholar
• Hsu CW, Imperiale TF. Meta-analysis and cost comparison of polyethylene glycol lavage versus sodium phosphate for colonoscopy preparation. Gastrointest Endosc 1998;48:276-82
   PubMed Web of Science ®Google Scholar
• Afridi SA, Barthel JS, King PD, et al. Prospective, randomized trial comparing a new sodium phosphate-bisacodyl regimen with conventional PEG-ES lavage for outpatient colonoscopy preparation. Gastrointest Endosc 1995;41:485-9
   PubMed Web of Science ®Google Scholar
• Young CJ, Simpson RR, King DW, et al. Oral sodium phosphate solution is a superior colonoscopy preparation to polyethylene glycol with bisacodyl. Dis Colon Rectum 2000;43:1568-71
   PubMed Web of Science ®Google Scholar
• Poon CM, Lee DW, Mak SK, et al. Two liters of polyethylene glycol-electrolyte lavage solution versus sodium phosphate as bowel cleansing regimen for colonoscopy: a prospective randomized controlled trial. Endoscopy 2002;34:560-3
   PubMed Web of Science ®Google Scholar
• Belsey J, Epstein O, Heresbach D. Systematic review: oral bowel preparation for colonoscopy. Aliment Pharmacol Ther 2007;25:373-84
   PubMed Web of Science ®Google Scholar
• Burke CA, Church JM. Enhancing the quality of colonoscopy: the importance of bowel purgatives. Gastrointest Endosc 2007;66:565-73
   PubMed Web of Science ®Google Scholar
• Tan JJ, Tjandra JJ. Which is the optimal bowel preparation for colonoscopy - a meta-analysis. Colorectal Dis 2006;8:247-58
   PubMed Web of Science ®Google Scholar
• Pereyra L, Cimmino D, González Malla C, et al. Colonic preparation before colonoscopy in constipated and non-constipated patients: a randomized study. World J Gastroenterol 2013;19:5103-10
   PubMed Web of Science ®Google Scholar
• Lee S, Lee D, Kim K, et al. Comparison of the efficacy and safety of sodium phosphate tablets and polyethylene glycol solution for bowel cleansing in healthy Korean adults. Yonsei Med J 2014;55:1542-55
   PubMed Web of Science ®Google Scholar
• Johanson JF, Popp JWJr, Cohen LB, et al. A randomized, multicenter study comparing the safety and efficacy of sodium phosphate tablets with 2L polyethylene glycol solution plus bisacodyl tablets for colon cleansing. Am J Gastroenterol 2007;102:2238-46
   PubMed Web of Science ®Google Scholar
• Jung YS, Lee CK, Kim HJ, et al. Randomized controlled trial of sodium phosphate tablets vs polyethylene glycol solution for colonoscopy bowel cleansing. World J Gastroenterol 2014;20:15845-51
   PubMed Web of Science ®Google Scholar
• Huynh T, Vanner S, Paterson W. Safety profile of 5-h oral sodium phosphate regimen for colonoscopy cleansing: lack of clinically significant hypocalcemia or hypovolemia. Am J Gastroenterol 1995;90:104-7
   PubMed Web of Science ®Google Scholar
• Korsten MA, Spungen AM, Rosman AR, et al. A prospective assessment of renal impairment after preparation for colonoscopy: oral sodium phosphate appears to be safe in well-hydrated subjects with normal renal status. Dig Dis Sci 2010;55:2021-9
   PubMed Web of Science ®Google Scholar
• Belsey J, Epstein O, Heresbach D. Systematic review: adverse event reports for oral sodium phosphate and polyethylene glycol. Aliment Pharmacol Ther 2009;29:15-28
   PubMed Web of Science ®Google Scholar
• FDA News Release December 11, 2008: FDA Requires New Safety Measures for Oral Sodium Phosphate Products to Reduce Risk of Acute Kidney Injury Risk associated with both prescription and over-the-counter (OTC) products. Available from: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2008/ucm116988.htm [Last accessed 10 January 2015]
   Google Scholar
• FDA Alert December 11, 2008: Information for Healthcare Professionals: Oral Sodium Phosphate (OSP) Products for Bowel Cleansing (marketed as Visicol and OsmoPrep, and oral sodium phosphate products available without a prescription). Available from: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationfor\PatientsandProviders/ucm126084.htm [Last accessed 10 January 2015]
   Google Scholar
• Rex DK, Vanner SJ. Colon cleansing before colonoscopy: does oral sodium phosphate solution still make sense? Can J Gastroenterol 2009;23:210-14
   PubMed Web of Science ®Google Scholar
• Seol DC, Hong SN, Kim JH, et al. Change in renal function after sodium phosphate preparation for screening colonoscopy. World J Gastroenterol 2010;16:2010-16
   PubMed Web of Science ®Google Scholar
• Ozturk NA, Gokturk HS, Demir M, et al. Efficacy and safety of sodium phosphate for colon cleansing in type 2 diabetes mellitus. South Med J 2010;103:1097-102
   PubMed Web of Science ®Google Scholar
• FDA Drug Safety Communication: FDA warns of possible harm from exceeding recommended dose of over-the-counter sodium phosphate products to treat constipation. Available from: http://www.fda.gov/Drugs/DrugSafety/ucm380757.htm [Last accessed 3 January 2015]
   Google Scholar
• Hsu HJ, Wu M. Extreme hyperphosphatemia and hypocalcemic coma associated with phosphate enema. Intern Med 2008;47:643-6
   PubMed Web of Science ®Google Scholar
• Jacobson RM, Peery J, Thompson WO, et al. Serum electrolyte shifts following administration of sodium phosphates enema. Gastroenterol Nurs 2010;33:191-201
   PubMed Web of Science ®Google Scholar
• Clarkston WK, Tsen TN, Dies DF, et al. Oral sodium phosphate versus sulfate-free polyethylene glycol electrolyte lavage solution in outpatient preparation for colonoscopy: a prospective comparison. Gastrointest Endosc 1996;43:42-8
   PubMed Web of Science ®Google Scholar
• DiPalma JA, Buckley SE, Warner BA, et al. Biochemical effects of oral sodium phosphate. Dig Dis Sci 1996;41:749-53
   PubMed Web of Science ®Google Scholar
• Casais M, Rosa Diez G, Bravo S, et al. Is the preparation with sodium phosphate purgative for bowel cleansing safe in low-risk patients? Acta Gastroenterol Latinoam 2010;40:54-60
   PubMedGoogle Scholar
• Juluri R, Eckert G, Imperiale TF. Meta-analysis: randomized controlled trials of 4-L polyethylene glycol and sodium phosphate solution as bowel preparation for colonoscopy. Aliment Pharmacol Ther 2010;32:171-81
   PubMed Web of Science ®Google Scholar
• Seo EH, Kim TO, Kim TG, et al. Efficacy and tolerability of split-dose PEG compared with split-dose aqueous sodium phosphate for outpatient colonoscopy: a randomized, controlled trial. Dig Dis Sci 2011;56:2963-71
   PubMed Web of Science ®Google Scholar
• Bae SE, Kim K, Eum JB, et al. A Comparison of 2 L of Polyethylene Glycol and 45 mL of Sodium Phosphate versus 4 L of Polyethylene Glycol for Bowel Cleansing: A Prospective Randomized Trial. Gut Liver 2013;7:423-9
   PubMed Web of Science ®Google Scholar
• Fine A, Patterson J. Severe hyperphosphatemia following phosphate administration for bowel preparation in patients with renal failure: two cases and a review of the literature. Am J Kidney Dis 1997;29:103-5
   PubMed Web of Science ®Google Scholar
• Orias M, Mahnensmith RL, Perazella MA. Extreme hyperphosphatemia and acute renal failure after a phosphorus-containing bowel regimen. Am J Nephrol 1999;19:60-3
   PubMed Web of Science ®Google Scholar
• Vukasin P, Weston LA, Beart RW. Oral Fleet Phospho-Soda laxative-induced hyperphosphatemia and hypocalcemic tetany in an adult: report of a case. Dis Colon Rectum 1997;40:497-9
   PubMed Web of Science ®Google Scholar
• Markowitz GS, Stokes MB, Radhakrishnan J, et al. Acute phosphate nephropathy following oral sodium phosphate bowel purgative: an underrecognized cause of chronic renal failure. J Am Soc Nephrol 2005;16:3389-96
   PubMed Web of Science ®Google Scholar
• Ahmed M, Raval P, Buganza G. Oral sodium phosphate catharsis and acute renal failure. Am J Gastroenterol 1996;91:1261-2
   PubMed Web of Science ®Google Scholar
• Ehrenpreis ED, Nogueras JJ, Botoman VA, et al. Serum electrolyte abnormalities secondary to Fleet’s Phospho-Soda colonoscopy prep. A review of three cases. Surg Endosc 1996;10:1022-4
   PubMed Web of Science ®Google Scholar
• Escalante CP, Weiser MA, Finkel K. Hyperphosphatemia associated with phosphorus-containing laxatives in a patient with chronic renal insufficiency. South Med J 1997;90:240-2
   PubMed Web of Science ®Google Scholar
• Boivin MA, Kahn SR. Symptomatic hypocalcemia from oral sodium phosphate: a report of two cases. Am J Gastroenterol 1998;93:2577-9
   PubMed Web of Science ®Google Scholar
• Ullah N, Yeh R, Ehrinpreis M. Fatal hyperphosphatemia from a phosphosoda bowel preparation. J Clin Gastroenterol 2002;34:457-8
   PubMed Web of Science ®Google Scholar
• Sica DA, Carl D, Zfass AM. Acute phosphate nephropathy--an emerging issue. Am J Gastroenterol 2007;102:1844-7
   PubMed Web of Science ®Google Scholar
• Ma RC, Chow CC, Yeung VT, et al. Acute renal failure following oral sodium phosphate bowel preparation in diabetes. Diabetes Care 2007;30:182-3
   PubMed Web of Science ®Google Scholar
• Becknell B, Smoyer WE, O’Brien NF. Hemodialysis for near-fatal sodium phosphate toxicity in a child receiving sodium phosphate enemas. Pediatr Emerg Care 2014;30:814-17
   PubMed Web of Science ®Google Scholar
• Gumurdulu Y, Serin E, Ozer B, et al. Age as a predictor of hyperphosphatemia after oral phosphosoda administration for colon preparation. J Gastroenterol Hepatol 2004;19:68-72
   PubMed Web of Science ®Google Scholar
• Lieberman DA, Ghormley J, Flora K. Effect of oral sodium phosphate colon preparation on serum electrolytes in patients with normal serum creatinine. Gastrointest Endosc 1996;43:467-9
   PubMed Web of Science ®Google Scholar
• Casais M, Rosa-Diez G, Perez S, et al. Hyperphosphatemia after sodium phosphate laxatives in low risk patients: prospective study. World J Gastroenterol 2009;15:5960-5
   PubMed Web of Science ®Google Scholar
• Ainley EJ, Winwood PJ, Begley JP. Measurement of serum electrolytes and phosphate after sodium phosphate colonoscopy bowel preparation: an evaluation. Dig Dis Sci 2005;50:1319-23
   PubMed Web of Science ®Google Scholar
• Lieberman DA, Ghormley J, Flora K. Effect of oral sodium phosphate colon preparation on serum electrolytes in patients with normal serum creatinine. Gastrointest Endosc 1996;43:467-9
   PubMed Web of Science ®Google Scholar
• Caswell M, Thompson WO, Kanapka JA, et al. The time course and effect on serum electrolytes of oral sodium phosphates solution in healthy male and female volunteers. Can J Clin Pharmacol 2007;14:e260-74
   PubMedGoogle Scholar
• Herlitz LC, D’Agati VD, Markowitz GS. Crystalline nephropathies. Arch Pathol Lab Med 2012;136:713-20
   PubMed Web of Science ®Google Scholar
• Stratta P, Barbieri S, Lazzarich E, et al. Nephrocalcinosis in phosphate nephropathy following oral phosphate purgative: a role for underlying subclinical primary hyperparathyroidism? Am J Kidney Dis 2007;50:1053; author reply 1053-4
   PubMed Web of Science ®Google Scholar
• Markowitz GS, Nasr SH, Klein P, et al. Renal failure due to acute nephrocalcinosis following oral sodium phosphate bowel cleansing. Hum Pathol 2004;35:675-84
   PubMed Web of Science ®Google Scholar
• Tan HL, Liew QY, Loo S, et al. Severe hyperphosphataemia and associated electrolyte and metabolic derangement following the administration of sodium phosphate for bowel preparation. Anaesthesia 2002;57:478-83
   PubMed Web of Science ®Google Scholar
• Rex DK. Phosphate nephropathy. Am J Gastroenterol 2008;103:807
   PubMed Web of Science ®Google Scholar
• Filho AJ, Lassman MN. Severe hyperphosphatemia induced by a phosphate-containing oral laxative. Ann Pharmacother 1996;30:141-3
   PubMed Web of Science ®Google Scholar
• Rostom A, Jolicoeur E, Dube C, et al. A randomized prospective trial comparing different regimens of oral sodium phosphate and polyethylene glycol-based lavage solution in the preparation of patients for colonoscopy. Gastrointest Endosc 2006;64:544-52
   PubMed Web of Science ®Google Scholar
• Korzets A, Dicker D, Chaimoff C, et al. Life-threatening hyperphosphatemia and hypocalcemic tetany following the use of fleet enemas. J Am Geriatr Soc 1992;40:620-1
   PubMed Web of Science ®Google Scholar
• Gutierrez E, Gonzalez E, Hernandez E, et al. Acute hyperphosphatemia secondary to phosphate administration for bowel preparation. Nefrologia 2004;24:283-7
   PubMed Web of Science ®Google Scholar
• Mishra R, Kaufman D, Mattern JIII, et al. Severe hyperphosphatemia and hypocalcemia caused by bowel preparation for colonoscopy using oral sodium phosphate in end-stage renal disease. Endoscopy 2005;37:1259-60
   PubMed Web of Science ®Google Scholar
• Azad BB, Cordtz J. Acute hyperphosphatemia in a dialysis patient after administration of sodium phosphate. Ugeskr Laeger 2009;171(17):1414
   PubMedGoogle Scholar
• Ma KK, Ng CS, Mui LM, et al. Severe hyperphosphatemia and hypocalcemia following sodium phosphate bowel preparation: a forgotten menace. Endoscopy 2003;35:717
   PubMed Web of Science ®Google Scholar
• Niemeijer ND, Rijk MC, van Guldener C. Symptomatic hypocalcemia after sodium phosphate preparation in an adult with asymptomatic hypoparathyroidism. Eur J Gastroenterol Hepatol 2008;20:356-8
   PubMed Web of Science ®Google Scholar
• Lien YH. Is bowel preparation before colonoscopy a risky business for the kidney? Nat Clin Pract Nephrol 2008;4:606-14
   PubMedGoogle Scholar
• Zaloga GP. Hypocalcemia in critically ill patients. Crit Care Med 1992;20:251-62
   PubMed Web of Science ®Google Scholar
• Desmeules S, Bergeron MJ, Isenring P. Acute phosphate nephropathy and renal failure. N Engl J Med 2003;349:1006-7
   PubMed Web of Science ®Google Scholar
• Asplin JR, Mandel NS, Coe FL. Evidence of calcium phosphate supersaturation in the loop of Henle. Am J Physiol 1996;270:F604-13
   PubMed Web of Science ®Google Scholar
• Aihara K, Byer KJ, Khan SR. Calcium phosphate-induced renal epithelial injury and stone formation: involvement of reactive oxygen species. Kidney Int 2003;64:1283-91
   PubMed Web of Science ®Google Scholar
• Umekawa T, Chegini N, Khan SR. Increased expression of monocyte chemoattractant protein-1 (MCP-1) by renal epithelial cells in culture on exposure to calcium oxalate, phosphate and uric acid crystals. Nephrol Dial Transplant 2003;18:664-9
   PubMed Web of Science ®Google Scholar
• Slee TM, Vleming LJ, Valentijn RM. Renal failure due to acute phosphate nephropathy. Neth J Med 2008;66:438-41
   PubMed Web of Science ®Google Scholar
• Anders H, Schlondorff D. Toll-like receptors: emerging concepts in kidney disease. Curr Opin Nephrol Hypertens 2007;16:177-83
   Google Scholar
• Wynn TA. Cellular and molecular mechanisms of fibrosis. J Pathol 2008;214:199-210
   PubMed Web of Science ®Google Scholar
• Gonlusen G, Akgun H, Ertan A, et al. Renal failure and nephrocalcinosis associated with oral sodium phosphate bowel cleansing: clinical patterns and renal biopsy findings. Arch Pathol Lab Med 2006;130:101-6
   PubMed Web of Science ®Google Scholar
• Ori Y, Herman M, Tobar A, et al. Acute phosphate nephropathy-an emerging threat. Am J Med Sci 2008;336:309-14
   PubMed Web of Science ®Google Scholar
• Markowitz GS, Perazella MA. Acute phosphate nephropathy. Kidney Int 2009;76:1027-34
   PubMed Web of Science ®Google Scholar
• Perkowska-Ptasinska A, Szewczyk K, Skuza A, et al. Phosphate nephropathy after administration of bowel purgative containing sodium phosphate - a case report. Pol J Pathol 2014;65:60-5
   PubMed Web of Science ®Google Scholar
• Wiech T, Hopfer H, Gaspert A, et al. Histopathological patterns of nephrocalcinosis: a phosphate type can be distinguished from a calcium type. Nephrol Dial Transplant 2012;27:1122-31
   PubMed Web of Science ®Google Scholar
• Eller P, Eller K, Kirsch AH, et al. A murine model of phosphate nephropathy. Am J Pathol 2011;178:1999-2006
   PubMed Web of Science ®Google Scholar
• Yarlagadda SG, Perazella MA. Drug-induced crystal nephropathy: an update. Expert Opin Drug Saf 2008;7:147-58
   PubMed Web of Science ®Google Scholar
• Markowitz GS, Radhakrishnan J, D’Agati VD. Towards the incidence of acute phosphate nephropathy. J Am Soc Nephrol 2007;18:3020-2
   PubMed Web of Science ®Google Scholar
• Palmadottir VK, Gudmundsson H, Hardarson S, et al. Incidence and outcome of acute phosphate nephropathy in Iceland. PLoS ONE 2010;5:e13484
   PubMedGoogle Scholar
• Florentin M, Liamis G, Elisaf MS. Colonoscopy preparation-induced disorders in renal function and electrolytes. World J Gastrointest Pharmacol Ther 2014;5:50-4
   Google Scholar
• Domico MB, Huynh V, Anand SK, Mink R. Severe hyperphosphatemia and hypocalcemic tetany after oral laxative administration in a 3-month-old infant. Pediatrics 2006;118:e1580-3
   PubMed Web of Science ®Google Scholar
• Butani L. Life-threatening hyperphosphatemia and hypocalcemia from inappropriate use of Fleet enemas. Clin Pediatr (Phila) 2005;44:93
   PubMed Web of Science ®Google Scholar
• Russmann S, Lamerato L, Marfatia A, et al. Risk of impaired renal function after colonoscopy: a cohort study in patients receiving either oral sodium phosphate or polyethylene glycol. Am J Gastroenterol 2007;102:2655-63
   PubMed Web of Science ®Google Scholar
• Abaskharoun R, Depew W, Vanner S. Changes in renal function following administration of oral sodium phosphate or polyethylene glycol for colon cleansing before colonoscopy. Can J Gastroenterol 2007;21:227-31
   PubMed Web of Science ®Google Scholar
• Khurana A, McLean L, Atkinson S, et al. The effect of oral sodium phosphate drug products on renal function in adults undergoing bowel endoscopy. Arch Intern Med 2008;168:593-7
   PubMed Web of Science ®Google Scholar
• Brunelli SM, Lewis JD, Gupta M, et al. Risk of kidney injury following oral phosphosoda bowel preparations. J Am Soc Nephrol 2007;18:3199-205
   PubMed Web of Science ®Google Scholar
• Ehrenpreis ED. Increased serum phosphate levels and calcium fluxes are seen in smaller individuals after a single dose of sodium phosphate colon cleansing solution: a pharmacokinetic analysis. Aliment Pharmacol Ther 2009;29:1202-11
   PubMed Web of Science ®Google Scholar
• Ehrenpreis ED, Parakkal D, Semer R, et al. Renal risks of sodium phosphate tablets for colonoscopy preparation: a review of adverse drug reactions reported to the US Food and Drug Administration. Colorectal Dis 2011;13:e270-5
   PubMed Web of Science ®Google Scholar
• Han HJ, Lee YH, Park KM, et al. Estradiol-17beta stimulates phosphate uptake and is mitogenic for primary rabbit renal proximal tubule cells. Exp Nephrol 2002;10:355-64
   PubMedGoogle Scholar
• Lim YJ, Hong SJ. What is the best strategy for successful bowel preparation under special conditions? World J Gastroenterol 2014;20:2741-5
   PubMed Web of Science ®Google Scholar
• Dykes C, Cash BD. Key safety issues of bowel preparations for colonoscopy and importance of adequate hydration. Gastroenterol Nurs 2008;31:30-5. quiz 36-7
   PubMed Web of Science ®Google Scholar
• Connor A, Tolan D, Hughes S, et al. Consensus guidelines for the safe prescription and administration of oral bowel-cleansing agents. Gut 2012;61:1525-32
   PubMed Web of Science ®Google Scholar
• Beyea A, Block C, Schned A. Acute phosphate nephropathy following oral sodium phosphate solution to cleanse the bowel for colonoscopy. Am J Kidney Dis 2007;50:151-4
   PubMed Web of Science ®Google Scholar
• Moon W. Optimal and safe bowel preparation for colonoscopy. Clin Endosc 2013;46:219-23
   Google Scholar
• Manley P, Somerfield J, Simpson I, et al. Bilateral uraemic optic neuritis complicating acute nephrocalcinosis. Nephrol Dial Transplant 2006;21:2957-8
   PubMed Web of Science ®Google Scholar
• Aasebo W, Scott H, Ganss R. Kidney biopsies taken before and after oral sodium phosphate bowel cleansing. Nephrol Dial Transplant 2007;22:920-2
   PubMed Web of Science ®Google Scholar
• Rocuts AK, Waikar SS, Alexander MP, et al. Acute phosphate nephropathy. Kidney Int 2009;75:987-91
   PubMed Web of Science ®Google Scholar
• Demoulin N, Jadoul M, Cosyns JP, et al. An easily overlooked iatrogenic cause of renal failure. Clin Nephrol 2008;70:176-7
   PubMed Web of Science ®Google Scholar
• Colic E, Marcussen N. Acute phosphate nephropathy as a complication to bowel cleansing with oral sodium phosphate. Ugeskr Laeger 2011;173:3270-1
   PubMedGoogle Scholar
• Weiss J, Thorp ML. Acute phosphate nephropathy: a cause of chronic kidney disease. BMJ Case Rep 2011;2011:bcr0420102876
   Google Scholar
• Steinman TI, Samir AE, Cornell LD. Case records of the Massachusetts General Hospital. Case 27-2008. A 64-year-old man with abdominal pain, nausea, and an elevated level of serum creatinine. N Engl J Med 2008;359:951-60
   PubMed Web of Science ®Google Scholar
• Connor A, Sykes L, Roberts IS, et al. Acute phosphate nephropathy after sodium phosphate preparations. BMJ 2008;337:a182
   PubMedGoogle Scholar
• Singal AK, Rosman AS, Post JB, et al. The renal safety of bowel preparations for colonoscopy: a comparative study of oral sodium phosphate solution and polyethylene glycol. Aliment Pharmacol Ther 2008;27:41-7
   PubMed Web of Science ®Google Scholar
• Kestenbaum B, Sampson JN, Rudser KD, et al. Serum phosphate levels and mortality risk among people with chronic kidney disease. J Am Soc Nephrol 2005;16:520-8
   PubMed Web of Science ®Google Scholar
• Santos P, Branco A, Silva S, et al. Acute phosphate nephropathy after bowel cleansing: still a menace. Nefrologia 2010;30:702-4
   PubMed Web of Science ®Google Scholar
• Han SH, Lee JE, Lee SH, et al. A case of acute phosphate nephropathy in a patient with nephrotic syndrome and decreased serum fetuin-A. Clin Nephrol 2010;74:159-63
   PubMed Web of Science ®Google Scholar
• Russmann S, Lamerato L, Motsko SP, et al. Risk of further decline in renal function after the use of oral sodium phosphate or polyethylene glycol in patients with a preexisting glomerular filtration rate below 60 ml/min. Am J Gastroenterol 2008;103:2707-16
   PubMed Web of Science ®Google Scholar
• Schattner A, Kopolovic J, Melzer E, et al. A 71-year-old woman with abdominal pain and acute renal failure. CMAJ 2007;177:454-5
   PubMed Web of Science ®Google Scholar
• Pannu N, Nadim MK. An overview of drug-induced acute kidney injury. Crit Care Med 2008;36:S216-23
   PubMed Web of Science ®Google Scholar
• Perazella MA. Crystal-induced acute renal failure. Am J Med 1999;106:459-65
   PubMed Web of Science ®Google Scholar
• WebMD. Osmoprep. Available from: http://www.webmd.com/drugs/2/drug-144293/osmoprep-oral/details#interactions [Last accessed 8 January 2015]
   Google Scholar
• Mackey AC, Green L, Amand KS, et al. Sodium phosphate tablets and acute phosphate nephropathy. Am J Gastroenterol 2009;104:1903-6
   PubMed Web of Science ®Google Scholar
• Cakar M, Kanbay M, Sarlak H, et al. Findings of biopsy-proven chronicity and end-stage renal failure associated with oral sodium phosphate solution. Ren Fail 2012;34:499-501
   PubMed Web of Science ®Google Scholar
• Seeff LC, Richards TB, Shapiro JA, et al. How many endoscopies are performed for colorectal cancer screening? Results from CDC’s survey of endoscopic capacity. Gastroenterology 2004;127:1670-7
   PubMed Web of Science ®Google Scholar
• Brunelli SM. Association between oral sodium phosphate bowel preparations and kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 2009;53:448-56
   PubMed Web of Science ®Google Scholar
• Layton JB, Klemmer PJ, Christiansen CF, et al. Sodium phosphate does not increase risk for acute kidney injury after routine colonoscopy, compared with polyethylene glycol. Clin Gastroenterol Hepatol 2014;12:1514-21.e3
   PubMed Web of Science ®Google Scholar
• Brady CEIII, DiPalma JA, Morawski SG, et al. Urinary excretion of polyethylene glycol 3350 and sulfate after gut lavage with a polyethylene glycol electrolyte lavage solution. Gastroenterology 1986;90:1914-18
   PubMed Web of Science ®Google Scholar
• Choi N, Lee J, Chang Y, et al. Acute renal failure following oral sodium phosphate bowel preparation: a nationwide case-crossover study. Endoscopy 2014;46:465-70
   PubMed Web of Science ®Google Scholar
• Hookey LC, Vanner S. Recognizing the clinical contraindications to the use of oral sodium phosphate for colon cleansing: a case study. Can J Gastroenterol 2004;18:455-8
   PubMed Web of Science ®Google Scholar
• Mathus-Vliegen E, Pellise M, Heresbach D, et al. Consensus guidelines for the use of bowel preparation prior to colonic diagnostic procedures: colonoscopy and small bowel video capsule endoscopy. Curr Med Res Opin 2013;29:931-45
   PubMed Web of Science ®Google Scholar
• Park JB, Lee YK, Yang CH. The evolution of bowel preparation and new developments. Korean J Gastroenterol 2014;63:268-75
   PubMedGoogle Scholar
• Wexner SD, Beck DE, Baron TH, et al. A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Gastrointest Endosc 2006;63:894-909
   PubMed Web of Science ®Google Scholar
• Hassan C, Bretthauer M, Kaminski MF, et al. Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy 2013;45:142-50
   PubMed Web of Science ®Google Scholar
• Shawki S, Wexner SD. How safe is bowel preparation with oral sodium phosphate solution? Nat Clin Pract Gastroenterol Hepatol 2008;5:482-3
   PubMedGoogle Scholar
• Lichtenstein GR, Cohen LB, Uribarri J. Review article: Bowel preparation for colonoscopy--the importance of adequate hydration. Aliment Pharmacol Ther 2007;26:633-41
   PubMed Web of Science ®Google Scholar
• Rao S, Calder wood AH. Safety first: the case against oral sodium phosphate. Endoscopy 2014;46:471-2
   PubMed Web of Science ®Google Scholar
• Marshall JB. Should oral sodium phosphate solution return as the first-line preparation for colonoscopy? Clin Gastroenterol Hepatol 2014;12:1522-4
   PubMed Web of Science ®Google Scholar