411
Views
50
CrossRef citations to date
0
Altmetric
Review

Anticonvulsant hypersensitivity syndrome: a review

, &
Pages 571-581 | Published online: 10 May 2005

Bibliography

  • BESSMERTNY 0, HATTON RC, GONZALEZ-PERALTA RP: Antiepileptic hypersensitivity syndrome in children. Ann. Pharmacother. (2001) 35(5):533–538.
  • KNOWLES SR, SHAPIRO LE, SHEAR NH: Anticonvulsant Hypersensitivity Syndrome. Incidence, Prevention and Management. Drug Sal (1999) 21(6):489–501.
  • VITTORIO CC, MUGLIA JJ: Anticonvulsant hypersensitivity syndrome. Arch. Intern. Med. (1995) 155(21):2285–2290
  • GILMAN JT, DUCHOWNY M: Introduction: Allergic Hypersensitivity to Antiepileptic Drugs: Past, Present, and Future. Epilepsia (1998) 39\(Supp 7):S1–S2.
  • TENNIS P, STERN R: Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study. Neurology (1997) 49(2):542–546.
  • ROUJEAU JC, STERN R: Severe adverse cutaneous reactions to drugs. N Engl. .1. Med. (1994) 331(19):1272–1285
  • SPIELBERG S, SHEAR N, HUTSON N et al: In-vitro assessment of hypersensitivity syndrome associated with sorbinil. Ann. Intern. Med. (1991) 114(9):701–724.
  • KNOWLES S, SHAPIRO L, SHEAR N: Serious adverse reactions induced by minocycline: a report of 13 patients and review of the literature. Arch. Dermatol (1996) 132(8):934–939.
  • GUPTA AK, KOPSTEIN JB, SHEAR NH: Hypersensitivity reaction to terbinafine. Am. Acad. Dermatol (1997) 36(6 Pt 1):1018–1019
  • KNOWLES SR, GUPTA AK, SHEAR NH, SAUDER D: Azathioprine hypersensitivity-like reactions- a case report and review of the literature. Clin. Exp. Dermatol (1995) 20(4):353–356.
  • MULLICK F, ISHAK F: Hepatic injury associated with diphenyl hydantoin therapy. Am. j Clin. Pathol (1980) 74(4)442–452.
  • AGUIR D, PAZO R, DURAN I et al: Toxic epidermal necrolysis in patients receiving anticonvulsants and cranial irradiation: a risk to consider. Neurooncol (2004) 66(3):345–350
  • ROUJEAU J-C, CHOSIDOW 0, SAIAG P, GUILLAUME J-C: Toxic epidermal necrolysis (Lyell Syndrome). Am. Acad. Dermatol (1990) 23(6 pt 1):1039–1058.
  • DREIFUSS FE, LANGER DH: Hepatic considerations in the use of antiepileptic drugs. Epilepsia (1987) 28\(Supp2):523–529.
  • SILVERMAN AK, FAIRLEY J, WONG RC: Cutaneous and immunologic reactions to phenytoin. J. Am. Acad. Dermatol (1988) 18(4 Part 1):721–741.
  • SPIELBERG S: In-vitro analysis of idiosyncratic drug reactions. Clin. Biochem. (1986) 19(2):142–144.
  • GLEICHMANN H: Studies on the mechanism of drug sensitization: T cell dependent popliteal lymph node reaction to diphynylhydantoin. Clin. Immunol Immunopathol (1981) 18(2):203–211.
  • KANO Y, INAOKA M, SHIOHARA T: Association between anticonvulsant hypersensitivity syndrome and human herpesvirus 6 reactivation and hypogammaglobulinemia. Arch. Dermatol (2004) 140(2):l83–l88.
  • SHEAR N, SPIELBERG S: Anticonvulsant hypersensitivity syndrome: In vitro assessment of risk. J. Clin. Invest. (1988) 82(6):1826–1832.
  • SPIELBERG S, GORDON G, BLAKE D, MELLITS ED, BROSS DS: Anticonvulsant toxicity in vitro: Possible role of arene oxides. J. Pharmacol Exp. Ther. (1981) 217(2):386–289.
  • RILEY F, LEEDER S: LI vitro analysis of metabolic predisposition to drug hypersensitivity reactions. Clin. Exp. Immunol (1995) 99(1):1–6.
  • SPIELBERG S, GORDON G, BLAKE D, GOLDSTEIN DA, HERLONG HF: Predisposition to phenytoin hepatotoxicity assessed in vitro. N Engl. I Med. (1981) 305(13):722–727.
  • FRIEDMANN P, STRICKLAND I, PIRMOHAMED M, PARK BK: Investigations of mechanisms in toxic epidermal necrolysis by carbamazepine. Arch. Dermatol (1994) 130(5):596–604.
  • LEEDER J, RILEY R, COOK V, SPIELBERG SP: Human anti-cytorchrome P450 antibodies in aromatic anticonvulsant-induced hypersensitivity reactions. J. Pharmacol Exp. Ther. (1992) 263(1):360–367.
  • MARTZ F, FEILINGER C, BLAKE DA: Phenytoin teratogenesis: Correlation between embryopathic effect and covalent binding of putative arene oxide metabolites in gestational tissue. I Pharmacol Exp. Ther. (1977) 203(1):231–239.
  • BENET LZ, MITCHELL JR, SHEINER LB: Pharmacokinetics: The dynamics of drug absorption, distribution and elimination. In: Goodman and Cilmadi The pharmacological basis of therapeutics (8th edition). Goodman Gilman A, Rall TW, Nies AS, Taylor P (Eds.) Pergamon Press, New York, (1991) Pp 3–32.
  • MORKUNAS AR, MILLER MB: Anticonvulsant hypersensitivity syndrome. Grit. Care Clin. (1997) 13(4):727–739.
  • BROWN TS, APPEL JE, KASTELER JS, CALLEN JP: Hypersensitivity reaction in a child due to lamotrigine. Pediatr. Dermatol (1999) 16(1):46–49.
  • MAGGS JL, NAISBITT DJ, TETTEY JN, PIRMOHAMED M, PARK BK: Metabolism of lamotrigine to a reactive arene oxide intermediate. Chem. Res. Toxicol (2000) 13(11):1075–1081.
  • PLANTIN P, CARTIER H, LE BIHAN G, CLOUARD P, LELLOUCHA F, LEROY JP: Syndrome d'hyeprsensibility medicamenteuse au cours. dun traitement par acide valproique. Presse Med. (1985) 24(34):1624.
  • NEUMANN MG, MALKIEWICZ IM, PHILLIPS EJ et al.: Monitoring adverse drug reactions to sulfonamide antibiotics in human immunodeficiency virus-infected individuals. Ther. Drug Monit. (2002) 24(6):728–736.
  • BELLER TC, BOYCE JA: Prolonged anticonvulsant hypersensitivity syndrome related to lamotrigine in a patient with human immunodeficiency virus. Allerg. Asthma Proc. (2002) 23(6):415–419.
  • LEEDER JS, RILEY RJ, COOK VA, SPIELBERG SP: Human anti-cytochrome P450 antibodies in aromatic anticonvulsant-induced hypersensitivity reactions. J. Pharmacol Exp. Ther. (1992) 263(1):360–367.
  • PIRMOHAMED M, KITTERINGHAM NR, BRECKENRIDGE AM, PARK BK: Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepinehypersensitivity. Br. J. Clin. Pharmacol (1992) 33(2):183–186.
  • RZANY B, CORREIA 0, KELLY JP, NALDI L, AUQUIER A, STERN R: Risk of Stevens-Johnson Syndrome and toxic epidermal necrolysis during first weeks of anti-epileptic therapy: a case control study. Study group of the International Case control study on Severe Cutaneous Adverse Reactions. Lancet (1999) 353(9171):2190–2194.
  • HARUDA F: Phenytoin hypersensitivity: 38 cases. Neurology (1979) 29(10:1480–1485.
  • SCHLIENGER RG, SHEAR NH: Antiepileptic drug hypersensitivity syndrome. Epilepsia (1998) 39\(Supp 7):53–57.
  • BABA M, KARAKAS M, AKSUNGUR VL, HOMAN S, YUCEL A, ACAR MA, MEMISOGLU HR: The anticonvulsant hypersensitivity syndrome. JEADV (2003) 17(4):399–401.
  • CIERNIK IF, THIEL M, WIDMER U: Anterior uveitis and the anticonvulsant hypersensitivity syndrome. Arch. Intern. Med. (1998) 158(2):192.
  • SCHREIBER M, McGREGOR J: Pseudolymphoma syndrome. Arch. Derm. (1968) 97(3):297–300.
  • D'INCAN N, SOUTEYRAND P, BIGNON Y, FONCK Y, ROGER H: Hydantoin-induced cutaneous pseudolymphoma with clinical, pathologic, and immunologic aspects of Sezary syndrome. Arch. Dermatol (1992) 128(10):1371–1374.
  • YATES P, STOCKDILL G, MCINTYRE M: Hypersensitivity to carbamazepine presenting as pseudolymphoma. I Clin. Pathol (1986) 39(10:1224–1228.
  • SHUTTLEWORTH D, GRAHAM-BROWN R, WILLIAMS A, CAMPBELL AC, SEWELL H: Pseudolymphoma associated with carbamazepine. Clin. Exp. Dermatol (1984) 9(4):421–423.
  • MOSTELLA J, PIERONI R, JOSE R, FINCH CK: Anticonvulsant hypersensitivity syndrome: Treatment with corticosteriods and intravenous immunoglobulin. Southern Med. (2004) 97(3):319–321.
  • BROWN CE, SMITH GD, CONIGLIONE T: Anticonvulsant hypersensitivity: an unfortunate case of triple exposure to phenytoin. I Fam. Pract. (1997) 45(5):434–437.
  • GRIEBEL ML: Acute management of hypersensitivity reactions and seizures. Epilepsia (1998) 39\(Supp 7):S17–S21.
  • TOUSSAINT S, KAMINO H. Non-infectious erythematous papular and squamous diseases of the skin. In: Lever S Histopathology of Skin (8th edition), Elder D (Ed.), Lippincott-Raven, Philadelphia (1997) Pp151–184.
  • ACKERMAN BA. Histologic diagnosis of inflammatory skin diseases, Philadephia Lea and Febiger (1978) Pp581–639.
  • BESSMERTNY 0, PHAM T: Anitepileptic hypersensitivity syndrome. Curr. Allergy Asthma Rep. (2002) 2(1):34–49.
  • PIRMOHAMED M, GRAHAM A, ROBERTS P et al.: Carbamazepine hypersensitivity: Assessment of clinical and in vitro chemical cross-reactivity with phenytoin and oxcarbazepine. Br. I Clin. Pharmacol (1991) 32(6):741–749.
  • NEUMAN MG, MALKIEWICZ IM, SHEAR NH: A novel LTA to assess drug hypersensitivity syndromes. Clin. Biochem. (2000) 33(7):517–524.
  • JONES M, FERNANDEZ-HERRERA J, DORADO J, SOLS M, RUIZ M, GARCIA-DIEZ A: Epicutaneous test in carbamazepine cutaneous reactions. Dermatology (1994) 188(1):18–20.
  • ALANKO K: Patch testing in cutaneous reactions caused by carbamazepine. Contact Dermatitis (1993) 29(5):254–257.
  • BERTZ RJ, HOWRIE DL: Diazepam by continuous intravenous infusion for status epilepticus in anticonvulsant hypersensitivity syndrome. Ann. Pharmacother. (1993) 27(3):298–301.
  • HAMER HM, MORRIS HH: Successful treatment with gabapentine in the presence of hypersensitivity syndrome to phenytoin and carbamazepine: a report of three cases. Seizure (1999) 8(3):190–192.
  • SCHEUERMAN 0, NOFECH-MOSES Y, RACHMEL A, ASHKENAZI S: Successful treatment of antiepileptic drug hypersensitivity syndrome with intravenous immunoglobulin. Pediatrics (2001) 107(1):E14.
  • BAVDEKAR SB, MURANJAN MN, GOGTAY NJ, KANTHARIA V, KSHIRSAGAR NA: Anticonyulsant hypersensitivity syndrome: Lymphocyte toxicity assay for the confirmation of diagnosis and risk assessment. Ann. Pharmacother. (2004) 38(10):1648–1650.
  • MANI KS, RANGAN G, SRINIVAS HV, SRINDHARAN VS, SUBBAKRISHNA DK: Epilepsy control with phenobarbital or phenytoin in rural south India: the Yelandur study. Lancet (2001) 357(9265):1316–1320.
  • DYER 0: New 20 year patents threaten toend AIDS drugs for developing countries. BE Med. J. (2004) 329(7478):1308.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.