Advanced search
Publication Cover
Expert Opinion on Drug Delivery Volume 6, 2009 - Issue 1
Submit an article Journal homepage
409
Views
36
CrossRef citations to date
0
Altmetric
Review

Nanoparticles for human liver-specific drug and gene delivery systems: in vitro and in vivo advances

Takeshi Kasuya Osaka University, Institute of Scientific and Industrial Research, Department of Structural Molecular Biology, Ibaraki, 567-0047, Osaka, Japan +81 6 6879 8462; +81 6 6879 8462; [email protected]
, PhD &
Shun'ichi Kuroda Osaka University, Institute of Scientific and Industrial Research, Department of Structural Molecular Biology, Ibaraki, 567-0047, Osaka, Japan +81 6 6879 8462; +81 6 6879 8462; [email protected]
, PhD
Pages 39-52 | Published online: 09 Jan 2009

Bibliography

  • Moghimi SM, Hunter AC, Murray JC. Long-circulating and target-specific nanoparticles: theory to practice. Pharmaco Rev 2001;53:283-318
  • Moghimi SM, Hunter AC, Murray JC. Nanomedicine: current status and future prospects. FASEB J 2005;19:311-30
  • Rahman YE, Rosenthal MW, Cerny EA. Intracellular plutonium: removal by liposome-encapsulated chelating agent. Science 1973;180:300-2
  • Yamada T, Iwasaki Y, Tada H, et al. Nanoparticles for the delivery of genes and drugs to human hepatocytes. Nat Biotechnol 2003;21:885-90
  • Ueki T, Kaneda Y, Tsutsui H, et al. Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med 1999;5:226-30
  • Lebherz C, Gao G, Louboutin JP, et al. Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia. J Gene Med 2004;6:663-72
  • Vandendriessche T, Vanslembrouck V, Goovaerts I, et al. Long-term expression of human coagulation factor VIII and correction of hemophilia A after in vivo retroviral gene transfer in factor VIII-deficient mice. Proc Natl Acad Sci USA 1999;96:10379-84
  • Maeda H, Wu J, Sawa T, et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release 2000;65:271-84
  • Drummond CD, Meyer O, Hong K, et al. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol Rev 1999;51:691-743
  • Snoeys J, Lievens J, Jacobs F, et al. Species differences in transgene DNA uptake in hepatocytes after adenoviral transfer correlate with the size of endothelial fenestrae. Gen Ther 2007;14:604-12
  • Bragonzi A, Diana G, Villa A, et al. Biodistribution and transgene expression with nonviral cationic vector/DNA complexes in the lungs. Gen Ther 2000;7:1753-60
  • Bangham AD, Horne RW. Negative staining of phospholipids and their structural modification by surface-active agents as observed in the electron microscope. J Mol Biol 1964;8:660-8
  • Fenske DB, Cullis PR. Liposomal nanomedicines. Expert Opin Drug Deliv 2008;5:25-44
  • Markman M. Pegylated liposomal doxorubicin in the treatment of cancers of the breast and ovary. Expert Opin Pharmacother 2006;7:1469-74
  • Lorusso V, Manizione L, Silvestris N. Role of liposomal anthracyclines in breast cancer. Ann Oncol 2007;18:70-3
  • Rosenthal E, Poizot-Martin I, Saint-Marc T, et al. Phase IV study of liposomal daunorubicin (DaunoXome) in AIDS-related Kaposi sarcoma. Am J Clin Oncol 2002;25:57-9
  • Richardson M. AmBisome. adds to the body of knowledge and familiarity of use. Acta Biomed 2006;77:3-11
  • Felgner PL, Gadek TR, Holm M. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA. 1987;84:7413-17
  • Woodle MC, Lasic DD. Sterically stabilized liposomes. Biochim Biophys Acta 1992;1113:171-99
  • Whitmore M, Li S, Huang L. LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Ther 1999;6:1867-75
  • Judge DA, Sood V, Shaw RJ, et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotech 2005;23:457-62
  • Sakurai H, Kawabata K, Sakurai F, et al. Innate immune response induced by gene delivery vectors. Int J Pharm 2008;354:9-15
  • Kataoka K, Harada A, Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv Drug Deliv Rev 2001;47:113-31
  • Aliabadi HM, Lavasanifar A. Polymeric micelles for drug delivery. Expert Opin Drug Deliv 2006;3:139-62
  • Uchegbu IF. Pharmaceutical nanotechnology: polymeric vesicles for drug and gene delivery. Expert Opin Drug Deliv 2006;3:629-640
  • Hughes JA, Rao GA. Targeted polymers for gene delivery. Expert Opin Drug Deliv 2005;2:145-57
  • Vasir JK, Labhasetwar V. Polymeric nanoparticles for gene delivery. Expert Opin Drug Deliv 2006;3:325-44
  • Zhang S, Zhao B, Jiang H, et al. Cationic lipids and polymers mediated vectors for delivery of siRNA. J Control Release 2007;123:1-10
  • Barnett BG, Crews CJ, Douglas JT. Targeted adenoviral vectors. Biochim Biophys Acta 2002;1575:1-14
  • Büning H, Ried MU, Perabo L, et al. Receptor targeting of adeno-associated virus vectors. Gene Ther 2003;10:1142-51
  • Anderson JL, Hope TJ. Intracellular trafficking of retroviral vectors: obstacles and advances. Gene Ther 2005;12:1667-278
  • Akita H, Ito R, Khali IA, et al. Quantitative three-dimensional analysis of the intracellular trafficking of plasmid DNA transfected by a nonviral gene delivery system using confocal laser scanning microscopy. Mol Ther 2004;9:443-51
  • Hama S, Akita H, Ito R, et al. Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems. Mol Ther 2006;13:786-94
  • Savulescu J. Harm, ethics committees and the gene therapy death. J Med Ethics 2001;27:148-50
  • Marshall E. Gene therapy a suspect in leukemia-like disease. Science 298:34-35
  • Grimm D, Streetz KL, Jopling CL, et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006;441:537-41
  • Ryan SM, Mantovani G, Wang X, et al. Advances in PEGylation of important biotech molecules: delivery aspects. Expert Opin Drug Deliv 2008;5:371-83
  • Kozolowski A, Harris JM. Improvements in protein PEGylation: pegylated interferons for treatment of hepatitis C. J Control Release 2001;72:217-24
  • Matthews SJ, Mccoy C. Peginterferon alfa-2a: a review of approved and investigational uses. Clin Ther 2004;26:991-1025
  • Guo X, Szoka FC JR. Steric stabilization of fusogenic liposomes by a low-pH sensitive PEG-diortho ester-lipid conjugate. Bioconjug Chem 2001;12:291-300
  • Shin J, Shum P, Thompson HD. Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG–lipids. J Control Release 2003;91:187-200
  • Hatakeyama H, Akita H, Kogure K, et al. Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid. Gene Ther 2007;14:68-77
  • Cheng TL, Wu PY, Wu MF, et al. Accelerated clearance of polyethylene glycol-modified proteins by anti-polyethylene glycol IgM. Bioconjug Chem 1999;10:520-8
  • Ishida T, Ichihara M, Wang X, et al. Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes. J Control Release 2006;115:243-50
  • Walker GF, Fella C, Pelisek J, et al. Toward synthetic viruses: endosomal pH-triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. Mol Ther 2005;11:418-25
  • Alexander C. Temperature- and pH-responsive smart polymers for gene delivery. Expert Opin Drug Deliv 2006;3:573-81
  • Zimmermann ST, Lee HCA, Akinc A, et al. RNAi-mediated gene silencing in non-human primates. Nature 2006;441:111-14
  • Baenziger JU, Maynard Y. Human hepatic lectin. Physiochemical properties and specificity. J Biol Chem 1980;255:4607-13
  • Wu GY, Wu CH. Receptor-mediated gene delivery and expression in vivo. J Biol Chem 1988;263:14621-4
  • Hashida M, Nishikawa M, Yamashita F, et al. Cell-specific delivery of genes with glycosylated carriers. Adv Drug Deliv Rev 2001;52:187-96
  • Hara T, Aramaki Y, Takeda S, et al. Receptor-mediated transfer of pSV2CAT DNA to mouse liver cells using asialofetuin-labeled liposomes. Gene Ther 1995;2:784-8
  • Wu J, Liu P, Zhu JL, et al. Increased liver uptake of liposomes and improved targeting efficacy by labeling with asialofetuin in rodents. Hepatology 1998;27:772-8
  • Rozema BD, Lewis LD, Wakefield HD, et al. Dynamic polyconjugates for targeted in vivo delivery of siRNA to hepatocytes. Proc Natl Acad Sci USA 2007;104:12982-7
  • Hiratsuka T, Goto M, Kondo Y, et al. Copolymers for hepatocyte-specific targeting carrying galactose and hydrophobic alkyl groups. Macromol Biosci 2008;8:231-8
  • Liu D, Mori A, Huang L. Large liposomes containing ganglioside GM1 accumulate effectively in spleen. Biochim Biophys Acta 1991;22:159-65
  • Gates SB, Mendelsohn LG, Shackelford KA, et al. Characterization of folate receptor from normal and neoplastic murine tissue: influence of dietary folate on folate receptor expression. Clin Can Res 1996;2:1135-41
  • Gabizon A, Horowitz AT, Goren D, et al. In vivo. fate of folate-targeted polyethylene-glycol liposomes in tumor-bearing mice. Clin Can Res 2003;9:6551-9
  • Cooper AD. Hepatic uptake of chylomicron remnants. J Lipid Res 1997;38:2173-92
  • Dierling AM, Cui Z. Targeting primaquine into liver using chylomicron emulsions for potential vivax malaria therapy. Int J Pharm 2005;303:143-52
  • Nishikawa M, Kamijo A, Fujita T, et al. Synthesis and pharmacokinetics of a new liver-specific carrier, glycosylated carboxymethyl-dextran, and its application to drug targeting. Pharm Res 1993;10:1253-61
  • Sato Y, Murase K, Kato J, et al. Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone. Nat Biotechnol 2008;26:431-42
  • Yu D, Amano C, Fukuda T, et al. The specific delivery of proteins to human liver cells by engineered bio-nanocapsules. FEBS J 2005;272:3651-560
  • Schödel F, Peterson D, Hughes J et al. Hybrid hepatitis B virus core antigen as a vaccine carrier moiety: I. presentation of foreign epitopes. J Biotechnol 1996;44:91-96
  • Kotani H, Nalajima T, Lai S, et al. The HVJ-envelope as an innovative vector system for cardiovascular disease. Curr Gene Ther 2004;4:183-94
  • Kuroda S, Otaka S, Miyazaki T, et al. Hepatitis B virus envelope L protein particles. Synthesis and assembly in Saccharomyces cerevisiae, purification and characterization. J Biol Chem 1992;267:1953-61
  • Yamada T, Iwabuki H, Kanno T, et al. Physicochemical and immunological characterization of hepatitis B virus envelope particles exclusively consisting of the entire L (pre-S1 + pre-S2 + S) protein. Vaccine 2001;19:3154-63
  • Kanno T, Yamada T, Iwabuki H, et al. Size distribution measurement of vesicles by atomic force microscopy. Anal Biochem 2002;309:196-9
  • Neurath AR, Kent SB, Strick N, et al. Identification and chemical synthesis of a host cell receptor binding site on hepatitis B virus. Cell 1986;46:429-36
  • Glebe D, Urban S. Viral and cellular determinants involved in hepadnaviral entry. World J Gastroenterol 2007;13:22-38
  • Kuroda S, Fujisawa Y, Iino S, et al. Induction of protection level of anti-pre-S2 antibodies in humans immunized with a novel hepatitis B vaccine consisting of M (pre-S2 + S) protein particles (a third generation vaccine). Vaccine 1991;9:163-9
  • Kasuya T, Nomura S, Matsuzaki T, et al. Expression of squamous cell carcinoma antigen-1 in liver enhances the uptake of hepatitis B virus envelope-derived bio-nanocapsules in transgenic rats. FEBS J 2008;275:5714-24
  • Iwasaki Y, Ueda M, Yamada T, et al. Gene therapy of liver tumors with human liver-specific nanoparticles. Cancer Gene Ther 2007;14:74-81
  • Khalil IA, Kogure K, Futaki S, et al. Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery. Gene Ther 2007;14:682-9
  • Wu X, Li QT. Ca2+-induced fusion of sulfatide-containing phosphatidylethanolamine small unilamellar vesicles. J Lipid Res 1999;40:1254-62
  • Oess S, Hildt E. Novel cell permeable motif derived from the PreS2-domain of hepatitis-B virus surface antigens. Gene Ther 2000;7:750-8
  • Nagaoka T, Fukuda T, Yoshida S, et al. Characterization of bio-nanocapsule as a transfer vector targeting human hepatocyte carcinoma by disulfide linkage modification. J Control Release 2007;118:348-56
  • Jung J, Matsuzaki T, Tatematsu K, et al. Bio-nanocapsule conjugated with liposomes for in vivo pinpoint delivery of various materials. J Control Release 2008;126:255-64
  • Tsutsui Y, Tomizawa K, Nagita M, et al. Development of bionanocapsules targeting brain tumors. J Control Release 2007;122:159-64
  • Kasuya T, Jung J, Kadoya H, et al. In vivo delivery of bio-nanocapsules displaying L4-PHA isolectin to malignant tumors overexpressing N-acetylglucosaminyltransferase V. Hum Gene Ther 2008;19:887-95
  • Lawrence D. Nanotechnology takes another small step forward. The Lancet 2003;362:48
  • Purcell RH. Hepatitis B virus mutants and efficacy of vaccination. The Lancet 2000;356:769-70

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.