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Expert Opinion on Drug Delivery Volume 6, 2009 - Issue 5
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Reviews

Carbon nanotubes in drug delivery: focus on infectious diseases

Yitzhak Rosen Superior NanoBioSystems LLC, 11722 Newbridge Court, Reston, Virginia, 20191, 385 N St., Southwest, Washington DC, 20024-2903, USA +1 301 909 7976; [email protected]
&
Noel M Elman Massachusetts Institute of Technology, Materials Science Engineering Department, Cambridge, Massachusetts, USA
Pages 517-530 | Published online: 12 May 2009

Bibliography

  • Iijima S. Helical microtubules of graphitic carbon. Nature 1991;354:56-8
  • Bianco A. Carbon nanotubes for the delivery of therapeutic molecules. Expert Opin Drug Deliv 2004;1(1):57-65
  • Prato M, Kostarelos K, Bianco A. Functionalized carbon nanotubes in drug design and discovery. Acc Chem Res 2008;41(1):60-8
  • Pantarotto D, Partidos CD, Graff R, et al. Synthesis, structural characterization, and immunological properties of carbon nanotubes functionalized with peptides. J Am Chem Soc 2003;125(20):6160-4
  • Tohji K, Akimoto Y, Shinoda K, et al. Kenichiro shibata preparation of carbon nanotubes for biomedical applications: length control, surface modification, and biocompatibility [abstract 585]. 205th Meeting, 2004 The Electrochemical Society, Inc
  • Bianco A, Kostarelos K, Prato M. Opportunities and challenges of carbon-based nanomaterials for cancer therapy. Expert Opin Drug Deliv 2008;5(3):331-42
  • Escorcia FE, McDevitt MR, Villa CH, Scheinberg DA. Targeted nanomaterials for radiotherapy. Nanomed 2007;2(6):805-15
  • Angelikopoulos P, Bock H. Directed self-assembly of surfactants in carbon nanotube materials. J Phys Chem B 2008;112(44):13793-801
  • Awasthi K, Srivastava A, Srivastava ON. Synthesis of carbon nanotubes. J Nanosci Nanotechnol 2005;5(10):1616-36
  • Thostenson ET, Ren ZF, Chou TW. Advances in the science and technology of carbon nanotubes and their composites: a review. Composites Sci Technol 2001;61(13):1899-912
  • Bianco A, Kostarelos K, Prato M. Applications of carbon nanotubes in drug delivery. Curr Opin Chem Biol 2005;9(6):674-9
  • Saito R, Dresselhaus G, Dresselhaus MS. Physical properties of carbon nanotubes. Imperial College Press. London, UK, 1998
  • Krajcik R, Jung A, Hirsch A, et al. Functionalization of carbon nanotubes enables non-covalent binding and intracellular delivery of small interfering RNA for efficient knock-down of genes. Biochem Biophys Res Commun 2008;369(2):595-602
  • Pantarotto D, Singh R, McCarthy D, et al. Functionalized carbon nanotubes for plasmid DNA gene delivery. Angew Chem Int Ed Engl 2004;43(39):5242-6
  • Singh R, Pantarotto D, McCarthy D, et al. Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors. J Am Chem Soc 2005;127(12):4388-96
  • Pantarotto D, Partidos CD, Hoebeke J, et al. Immunization with peptide-functionalized carbon nanotubes enhances virus-specific neutralizing antibody responses. Chem Biol 2003;10(10):961-6
  • Yacoby I, Benhar I. Antibacterial nanomedicine. Nanomed 2008;3(3):329-41
  • Chakravarty P, Marches R, Zimmerman NS, et al. Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes. Proc Natl Acad Sci USA 2008;105(25):8697-702
  • Dumortier H, Lacotte S, Pastorin G, et al. Functionalized carbon nanotubes are non-cytotoxic and preserve the functionality of primary immune cells. Nano Lett 2006;6(7):1522-8
  • McDevitt MR, Chattopadhyay D, Kappel BJ, et al. Tumor targeting with antibody functionalized, radiolabeled carbon nanotubes. J Nucl Med 2007;48:1180-9
  • McDevitt MR, Chattopadhyay D, Jaggi JS, et al. PET imaging of soluble yttrium-86-labeled carbon nanotubes in mice. PLoS ONE 2007;2(9):e907
  • Ali-boucetta H, Al-jamal KT, Mccarthy D, et al. Multiwalled carbon nanotube-doxorubicin supramolecular complexes for cancer therapeutics. Chem Commun 2008;(4):459-61
  • Lam CW, James JT, McCluskey R, et al. A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks. Crit Rev Toxicol 2006;36(3):189-217
  • Borrelli I. Nanotubes and occupational medicine. Article in Italian. G Ital Med Lav Ergon 2007;29(3 Suppl):851-2
  • Magrez A, Kasas S, Salicio V, et al. Cellular toxicity of carbon-based nanomaterials. Nano Lett 2006;6(6):1121-5
  • Cohen ML. Epidemiology of drug resistance: implications for a post-antimicrobial era. Science 1992;257(5073):1050-5
  • Aarestrup FM, Wegener HC, Collignon P. Resistance in bacteria of the food chain: epidemiology and control strategies. Expert Rev Anti Infect Ther 2008;6(5):733-50
  • Banerjee R, Schecter GF, Flood J, Porco TC. Extensively drug-resistant tuberculosis: new strains, new challenges. Expert Rev Anti Infect Ther 2008;6(5):713-24
  • Pitout JD. Multiresistant Enterobacteriaceae: new threat of an old problem. Expert Rev Anti Infect Ther 2008;6(5):657-69
  • Arias CA, Murray BE. Emergence and management of drug-resistant enterococcal infections. Expert Rev Anti Infect Ther 2008;6(5):637-55
  • Mandell GL, Bennett JE, Dolin R. Principles and practice of infectious diseases. Sixth edition. Churchill Livingstone. Various pages. 2004
  • Harrison's principles of internal medicine. Sixteenth edition. In: Kasper D, Braunwald E, Hauser S, Longo D, Jameson JL, Fauci AS, editors, McGraw-Hill Professional 2004, various pages
  • Georgakilas V, Kordatos K, Prato M, et al. Organic functionalization of carbon nanotubes. J Am Chem Soc 2002;124(5):760-1
  • Pastorin G, Wu W, Wieckowski S, et al. Double functionalization of carbon nanotubes for multimodal drug delivery. Chem Commun 2006;(11):1182-4
  • Kam NW, Liu Z, Dai H. Functionalization of carbon nanotubes via cleavable disulfide bonds for efficient intracellular delivery of siRNA and potent gene silencing. J Am Chem Soc 2005;127(36):12492-3
  • Singh R, Pantarotto D, Lacerda L, et al. Tissue biodistribution and blood clearance rates of intravenously administered carbon nanotube radiotracers. Proc Natl Acad Sci USA 2006;103(9):3357-62
  • Bottini M, Bruckner S, Nika K, et al. Multi-walled carbon nanotubes induce T lymphocyte apoptosis. Toxicol Lett 2006;160(2):121-6
  • Liu J, Rinzler AG, Dai H, et al. Fullerene pipes. Science 1998;280(5367):1253-6
  • Bottini M, Tautz L, Huynh H, et al. Covalent decoration of multi-walled carbon nanotubes with silica nanoparticles. Chem Commun 2005;(6):758-60
  • Georgakilas V, Tagmatarchis N, Pantarotto D, et al. Amino acid functionalisation of water soluble carbon nanotubes. Chem Commun 2002;(24):3050-1
  • Isobe H, Tanaka T, Maeda R, et al. Preparation, purification, characterization, and cytotoxicity assessment of water-soluble, transition-metal-free carbon nanotube aggregates. Angew Chem Int Ed Engl 2006;45(40):6676-80
  • Wu W, Wieckowski S, Pastorin G, et al. Targeted delivery of Amphotericin B to cells by using functionalized carbon nanotubes. Angew Chem Int Ed Engl 2005;44(39):6358-62
  • Pantarotto D, Briand JP, Prato M, Bianco A. Translocation of bioactive peptides across cell membranes by carbon nanotubes. Chem Commun 2004;(1):16-7
  • Shi Kam NW, Jessop TC, Wender PA, Dai H. Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells. J Am Chem Soc 2004;126(22):6850-1
  • Tasis D, Tagmatarchis N, Bianco A, Prato M. Chemistry of carbon nanotubes. Chem Rev 2006;106(3):1105-36
  • Tasis D, Tagmatarchis N, Georgakilas V, Prato M. Soluble carbon nanotubes. Chemistry 2003;9(17):4000-8
  • Fu K, Sun YP. Dispersion and solubilization of carbon nanotubes. J Nanosci Nanotechnol 2003;3(5):351-64
  • Chang LW, Lue JT. Electrical conductance in a single carbon nanofiber. J Nanosci Nanotechnol 2005;5(10):1672-6
  • Kostarelos K, Lacerda L, Pastorin G, et al. Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. Nat Nanotechnol 2007;2(2):108-13
  • Lacerda L, Bianco A, Prato M, Kostarelos K. Carbon nanotube cell translocation and delivery of nucleic acids in vitro and in vivo. J Mater Chem 2008;(18):17-22
  • Liu Z, Sun X, Nakayama-ratchford N, Dai H. Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery. ACS Nano 2007;1(1):50-6
  • Cui D, Tian F, Ozkan CS, et al. Effect of single wall carbon nanotubes on human HEK293 cells. Toxicol Lett 2005;155(1):73-85
  • Monteiro-Riviere NA, Nemanich RJ, Inman AO, et al. Multi walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 2005;155(3):377-84
  • Huang XM, Caldwell R, Huang L, et al. Hone Controlled placement of individual carbon nanotubes. J Nano Lett 2005;5(7):1515-8
  • Du Z, Yu YL, Chen XW, Wang JH. The isolation of basic proteins by solid-phase extraction with multiwalled carbon nanotubes. Chemistry 2007;13(34):9679-85
  • Salvador-Morales C, Basiuk EV, Basiuk VA, et al. Effects of covalent functionalization on the biocompatibility characteristics of multi-walled carbon nanotubes. J Nanosci Nanotechnol 2008;8(5):2347-56
  • Zou J, Ji B, Feng XQ, Gao H. Molecular-dynamic studies of carbon-water-carbon composite nanotubes. Small 2006;2(11):1348-55
  • Pillai SK, Ray SS, Moodley M. Purification of single-walled carbon nanotubes. J Nanosci Nanotechnol 2007;7(9):3011-47
  • Reilly RM. Carbon nanotubes: potential benefits and risks of nanotechnology in nuclear medicine. J Nucl Med 2007;48(7):1039-42
  • Star A, Steuerman DW, Heath JR, Stoddart JF. Starched carbon nanotubes. Angew Chem Int Ed Engl 2002;41(14):2508-12
  • Cirz RT, Chin JK, Andes DR, et al. Inhibition of mutation and combating the evolution of antibiotic resistance. PLoS Biol 2005;3(6):e176
  • Cohen ML. Epidemiology of drug resistance – implications for a postantimicrobial era. Science 1992;257(5073):1050-5
  • Bowdish DM, Davidson DJ, Hancock RE. A re-evaluation of the role of host defence peptides in mammalian immunity. Curr Protein Pept Sci 2005;6(1):35-51
  • Agerberth B, Gudmundsson GH. Host antimicrobial defence peptides in human disease. Curr Top Microbiol Immunol 2006;306:67-90
  • Brady-Estevez AS, Kang S, Elimelech M. A single-walled carbon nanotube filter for removal of viral and bacterial pathogens. Small 2008;(4):81-484
  • Elimelech M. Carbon nanotubes kill bacteria. Mater Technol 2007;(3):79-179
  • Kang S, Herzberg M, Rodrigues DF, Elimelech M. Antibacterial effects of carbon nanotubes: size does matter. Langmuir 2008;24(13):6409-13
  • Kang S, Mauter MS, Elimelech M. Physicochemical determinants of multiwalled carbon nanotube bacterial cytotoxicity. Environ Sci Technol 2008;42(19):7528-34
  • Kang S, Pinault M, Pfefferle LD, Elimelech M. Single-walled carbon nanotubes exhibit strong antimicrobial activity. Langmuir 2007;23(17):8670-3
  • Muller J, Huaux F, Moreau N, et al. Respiratory toxicity of multi-wall carbon nanotubes. Toxicol Appl Pharmacol 2005;207(3):221-31
  • Warheit DB, Laurence BR, Reed KL, et al. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol Sci 2004;77(1):117-25
  • Medina C, Santos-Martinez MJ, Radomski A, et al. Nanoparticles: pharmacological and toxicological significance. Br J Pharmacol 2007;150(5):552-8 [Epub 2007 Jan 22]
  • De Jong WH, Borm PJ. Drug delivery and nanoparticles: applications and hazards. Int J Nanomedicine 2008;3(2):133-49
  • Lanone S, Boczkowski J. Biomedical applications and potential health risks of nanomaterials: molecular mechanisms. Curr Mol Med 2006;6(6):651-63
  • Tian F, Cui D, Schwarz H, et al. Cytotoxicity of single-wall carbon nanotubes on human fibroblasts. Toxicol In Vitro 2006;20(7):1202-12
  • Wörle-Knirsch JM, Pulskamp K, Krug HF. Oops they did it again! Carbon nanotubes hoax scientists in viability assays. Nano Lett 2006;6(6):1261-8
  • Takagi A, Hirose A, Nishimura T, et al. Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 2008;33(1):105-16
  • Lam CW, James JT, McCluskey R, Hunter RL. Pulmonary toxicity of single-wall arbon nanotubes in mice 7 and 90 days after intratracheal instillation. Toxicol ci 2004;77(1):126-34
  • Joshi RP, Schoenbach KH. Mechanism for membrane electroporation rreversibility under high-intensity, ultrashort electrical pulse conditions. Phys Rev E Stat Nonlin Soft Matter Phys 2002;66(5 Pt 1):052901
  • Rojas-Chapana JA, Correa-duarte MA, Ren ZF, et al. Enhanced introduction of gold nanoparticles into vital acidothiobacillus ferrooxidans by carbon nanotube-based microwave electroporation. Nano Lett 2004;4(5):985-8
  • Rojas-Chapana J, Troszczynska J, Firkowska I, et al. Multiwalled carbon nanotubes for plasmid delivery into Escherichia coli cells. Lab Chip 2005;5(5):536-9
  • Walther W, Stein U. Viral vectors for gene transfer: a review of their use in the treatment of human diseases. Drugs 2000;60(2):249-71
  • Bokhoven M, Stephen SL, Knight S, et al. Insertional gene activation by lentiviral and gammaretroviral vectors. J Virol 2008
  • Itaka K, Kataoka K. Recent development of non-viral gene delivery systems with virus-like structures and mechanisms. Eur J Pharm Biopharm 2008
  • Zein NN, Rakela J, Krawitt EL, et al. Hepatitis C virus genotypes in the United States: epidemiology, pathogenicity, and response to interferon therapy. Collaborative Study Group. Ann Intern Med 1996;125(8):634-9
  • Sharara AI, Hunt CM, Hamilton JD. Hepatitis C. Ann Intern Med 1996;125(8):658-68
  • Resnick RH, Koff R. Hepatitis C-related hepatocellular carcinoma. Prevalence and significance. Arch Intern Med 1993;153(14):1672-7
  • Cholongitas E, Papatheodoridis GV. Review article: novel therapeutic options for chronic hepatitis C. Aliment Pharmacol Ther 2008;27(10):866-84
  • Zhang H, Hanecak R, Brown-Driver V, et al. Antisense oligonucleotide inhibition of hepatitis C virus (HCV) gene expression in livers of mice infected with an HCV-vaccinia virus recombinant. Antimicrob Agents Chemother 1999;43(2):347-53
  • Agrawal S, Lisziewicz J. Potential for HIV-1 treatment with antisense oligonucleotides. J Biotechnol 1994;Healthcare 1:167-82
  • Alt M, Renz R, Hofschneider PH, et al. Specific inhibition of hepatitis C viral gene expression by antisense phosphorothioate oligodeoxynucleotides. Hepatology 1995;22(3):707-17
  • Anderson KP, Fox MC, Brown-Driver V, et al. Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA. Antimicrob Agents Chemother 1996;40(9):2004-11
  • Azad RF, Driver VB, Tanaka K, et al. Antiviral activity of a phosphorothioate oligonucleotide complementary to RNA of the human cytomegalovirus major immediate-early region. Antimicrob Agents Chemother 1993;37(9):1945-54
  • Offensperger WB, Offensperger S, Walter E, et al. In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides. EMBO J 1993;12(3):1257-62
  • Raviprakash K, Liu K, Matteucci M, et al. Inhibition of dengue virus by novel, modified antisense oligonucleotides. J Virol 1995;69(1):69-74
  • Vidalin O, Major ME, Rayner B, et al. In vitro inhibition of hepatitis C virus gene expression by chemically modified antisense oligodeoxynucleotides. Antimicrob Agents Chemother 1996;40(10):2337-44
  • Bennett CF, Kornbrust D, Henry S, et al. An ICAM-1 antisense oligonucleotide prevents and reverses dextran sulfate sodium-induced colitis in mice. J Pharmacol Exp Ther 1997;280(2):988-1000
  • Crooke ST. Therapeutic applications of oligonucleotides. Annu Rev Pharmcol Toxicol 1992;32:329-76
  • Crooke ST. Oligonucleotide therapeutics. Fifth edition. In: Wolff ME, editor, Burger's medicinal chemistry and drug discovery, John Wiley & Sons, Inc., New York, N.Y. 1995 vol. 1. p. 863-900
  • Dean N, McKay R, Miraglia L, et al. Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression. Cancer Res 1996;56(15):3499-507
  • Monia BP, Johnston JF, Geiger T, et al. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat Med 1996;2(6):668-75
  • Higgins KA, Perez JR, Coleman TA, et al. Antisense inhibition of the p65 subunit of NFkappa B blocks tumorigenicity and causes tumor regression. Proc Natl Acad Sci USA 1993;90(21):9901-5
  • Cui D, Tian F, Coyer SR, et al. Effects of antisense-myc-conjugated single-walled carbon nanotubes on HL-60 cells. J Nanosci Nanotechnol 2007 ;7(4-5):1639-46
  • Chevalier C, Saulnier A, Benureau Y, et al. Inhibition of hepatitis C virus infection in cell culture by small interfering RNAs. Mol Ther 2007;15(8):1452-62
  • Bellmann R. Clinical pharmacokinetics of systemically administered antimycotics. Curr Clin Pharmacol 2007;2(1):37-58
  • Aguzzi A. Unraveling prion strains with cell biology and organic chemistry. Proc Natl Acad Sci USA 2008;105(1):11-2
  • Center for Disease Control Website: Available from: www.cdc.gov/ncidod/dvrd/prions/
  • Toupet K, Compan V, Crozet C, et al. Effective gene therapy in a mouse model of prion diseases. PLoS ONE 2008;3(7):e2773
  • Liu Z, Cai W, He L, et al. In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice. Nat Nanotechnol 2007;2(1):47-52
  • Liu Z, Chen K, Davis C, et al. Drug delivery with carbon nanotubes for in vivo cancer treatment. Cancer Res 2008;68(16):6652-60
  • Schipper ML, Nakayama-Ratchford N, Davis CR, et al. A pilot toxicology study of single-walled carbon nanotubes in a small sample of mice. Nat Nanotechnol 2008;3(4):216-21
  • Lacerda L, Herrero MA, Venner K, et al. Carbon nanotube shape and individualization critical for renal excretion. Small 2008;4(8):1130-2
  • Lacerda L, Ali-Boucetta H, Herrero MA, et al. Tissue histology and physiology following intravenous administration of different types of functionalized multiwalled carbon nanotubes. Nanomed 2008;3(2):149-61
  • Poland CA, Duffin R, Kinloch I, et al. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 2008;3(7):423-8
  • Lippmann M. Nature of exposure to chrysotile. Ann Occup Hyg 1994;38(4):459-67, 408
  • Kostas Kostarelos. The good, the bad and ugly nanomaterials in biology – learning from the carbon nanotube experience. 2nd International Conference on Nanotoxicology, Zurich, Switzerland. September 7–10, 2008, page 6, section 1.1

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