Nuclear targeting of viral and non-viral DNA

Bibliography

• Chowdhury EH. Self-assembly of DNA and cell-adhesive proteins onto pH-sensitive inorganic crystals for precise and efficient transgene delivery. Curr Pharm Des 2008;14:2212-28
   PubMed Web of Science ®Google Scholar
• Chowdhury EH. pH-sensitive nano-crystals of carbonate apatite for smart and cell-specific transgene delivery. Expert Opin Drug Deliv 2007;4:193-6
   PubMed Web of Science ®Google Scholar
• Chowdhury EH, Akaike T. Bio-functional inorganic materials: an attractive branch of gene-based nano-medicine delivery for 21st century. Curr Gene Ther 2005;5:669-76
   PubMed Web of Science ®Google Scholar
• Lechardeur D, Sohn KJ, Haardt M, et al. Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer. Gene Ther 1999;6:482-97
   PubMed Web of Science ®Google Scholar
• Capecchi MR. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 1980;22:479-88
   PubMed Web of Science ®Google Scholar
• Mirzayans R, Aubin RA, Paterson MC. Differential expression and stability of foreign genes introduced into human fibroblasts by nuclear versus cytoplasmic microinjection. Mutat Res 1992;281:115-22
   PubMed Web of Science ®Google Scholar
• Wilke M, Fortunati E, Van Den Broek M, et al. Efficacy of a peptide-based gene delivery system depends on mitotic activity. Gene Ther 1996;3:1133-42
   PubMed Web of Science ®Google Scholar
• Fasbender A, Zabner J, Zeiher BG, et al. A low rate of cell proliferation and reduced DNA uptake limit cationic lipid-mediated gene transfer to primary cultures of ciliated human airway epithelia. Gene Ther 1997;4:1173-80
   PubMed Web of Science ®Google Scholar
• Sebestyén MG, Ludtke JJ, Bassik MC, et al. DNA vector chemistry: the covalent attachment of signal peptides to plasmid DNA. Nat Biotechnol 1998;16:80-5
   PubMed Web of Science ®Google Scholar
• Tseng WC, Haselton FR, Giorgio TD. Mitosis enhances transgene expression of plasmid delivered by cationic liposomes. Biochim Biophys Acta 1999;1445:53-64
   PubMed Web of Science ®Google Scholar
• Mortimer I, Tam P, Maclachlan I, et al. Cationic lipid-mediated transfection of cells in culture requires mitotic activity. Gene Ther 1999;6:403-11
   PubMed Web of Science ®Google Scholar
• Liu G, Li D, Pasumarthy MK, et al. Nanoparticles of compacted DNA transfect postmitotic cells. J Biol Chem 2003;278:32578-86
   PubMed Web of Science ®Google Scholar
• Pollard H, Remy JS, Loussouarn G, et al. Polyethylenimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J Biol Chem 1998;273:7507-11
   PubMed Web of Science ®Google Scholar
• Feldherr CM, Akin D. Signal-mediated nuclear transport in proliferating and growth-arrested BALB/c 3T3 cells. J Cell Biol 1991;115:933-9
   PubMed Web of Science ®Google Scholar
• Peters R. Nucleo-cytoplasmic flux and intracellular mobility in single hepatocytes measured by fluorescence microphotolysis. EMBO J 1984;3:1831-6
   PubMed Web of Science ®Google Scholar
• Akey CW. Visualization of transport-related configurations of the nuclear pore transporter. Biophys J 1990;58:341-55
   PubMed Web of Science ®Google Scholar
• Feldherr CM, Akin D. The location of the transport gate in the nuclear pore complex. J Cell Sci 1997;10:3065-70
   Google Scholar
• Ludtke JJ, Zhang G, Sebestyen MG, et al. A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA. J Cell Sci 1999;112:2033-41
   PubMed Web of Science ®Google Scholar
• Kalderon D, Roberts BL, Richardson WD, et al. A short amino acid sequence able to specify nuclear location. Cell 1984;39:499-509
   PubMed Web of Science ®Google Scholar
• Dworetzky SI, Lanford RE, Feldherr CM. The effects of variations in the number and sequence of targeting signals on nuclear uptake. J Cell Biol 1988;107:1279-87
   PubMed Web of Science ®Google Scholar
• Pouton CW. Nuclear import of polypeptides, polynucleotides and supramolecular complexes. Adv Drug Deliv Rev 1998;34:51-64
   PubMed Web of Science ®Google Scholar
• Kalderon D, Roberts BL, Richardson WD, et al. A short amino acid sequence able to specify nuclear location. Cell 1984;39:499-509
   PubMed Web of Science ®Google Scholar
• Kalderon D, Richardson WD, Markham AF, et al. Sequence requirements for nuclear location of simian virus 40 large-T antigen. Nature 1984;311:33-8
   PubMed Web of Science ®Google Scholar
• Robbins J, Dilworth SM, Laskey RA, et al. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 1991;64:615-23
   PubMed Web of Science ®Google Scholar
• Rexach M, Blobel G. Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell 1995;83:683-92
   PubMed Web of Science ®Google Scholar
• Hu T, Guan T, Gerace L. Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. J Cell Biol 1996;134:589-601
   PubMed Web of Science ®Google Scholar
• Whittaker GR. Virus nuclear import. Adv Drug Deliv Rev 2003;55:733-47
   PubMed Web of Science ®Google Scholar
• Shahin V, Hafezi W, Oberleithner H, et al. The genome of HSV-1 translocates through the nuclear pore as a condensed rod-like structure. J Cell Sci 2006;119:23-30
   PubMed Web of Science ®Google Scholar
• Greber UF, Fassati A. Nuclear import of viral DNA genomes. Traffic 2003;4:136-43
   PubMed Web of Science ®Google Scholar
• Izaurralde E, Kann M, Panté N, et al. Viruses, microorganisms and scientists meet the nuclear pore. 26 February–1 March 1998, Leysin, VD, Switzerland. EMBO J 1999;18:289-96
   PubMedGoogle Scholar
• Leopold PL, Ferris B, Grinberg I, et al. Fluorescent virions: dynamic tracking of the pathway of adenoviral gene transfer vectors in living cells. Hum Gene Ther 1998;9:367-78
   PubMed Web of Science ®Google Scholar
• Leopold PL, Kreitzer G, Miyazawa N, et al. Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis. Hum Gene Ther 2000;11:151-65
   PubMed Web of Science ®Google Scholar
• Suomalainen M, Nakano MY, Keller S, et al. Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus. J Cell Biol 1999;144:657-72
   PubMed Web of Science ®Google Scholar
• Suomalainen M, Nakano MY, Boucke K, et al. Adenovirus-activated PKA and p38/MAPK pathways boost microtubule-mediated nuclear targeting of virus. EMBO J 2001;20:1310-9
   PubMed Web of Science ®Google Scholar
• Mabit H, Nakano MY, Prank U, et al. Intact microtubules support adenovirus and herpes simplex virus infections. J Virol 2002;76:9962-71
   PubMed Web of Science ®Google Scholar
• Kelkar SA, Pfister KK, Crystal RG, et al. Cytoplasmic dynein mediates adenovirus binding to microtubules. J Virol 2004;78:10122-32
   PubMed Web of Science ®Google Scholar
• Saphire AC, Guan T, Schirmer EC, et al. Nuclear import of adenovirus DNA in vitro involves the nuclear protein import pathway and hsc70. J Biol Chem 2000;275:4298-304
   PubMed Web of Science ®Google Scholar
• Hindley CE, Lawrence FJ, Matthews DA. A role for transportin in the nuclear import of adenovirus core proteins and DNA. Traffic 2007;8:1313-22
   PubMed Web of Science ®Google Scholar
• Wisnivesky JP, Leopold PL, Crystal RG. Specific binding of the adenovirus capsid to the nuclear envelope. Hum Gene Ther 1999;10:2187-95
   PubMed Web of Science ®Google Scholar
• Trotman LC, Mosberger N, Fornerod M, et al. Import of adenovirus DNA involves the nuclear pore complex receptor CAN/Nup214 and histone H1. Nat Cell Biol 2001;3:1092-100
   PubMed Web of Science ®Google Scholar
• Chapman MS, Rossmann MG. Structure, sequence, and function correlations among parvoviruses. Virology 1993;194:491-508
   PubMed Web of Science ®Google Scholar
• Vihinen-Ranta M, Kalela A, Mäkinen P. Intracellular route of canine parvovirus entry. J Virol 1998;72:802-6
   PubMed Web of Science ®Google Scholar
• Weichert WS, Parker JS, Wahid AT. Assaying for structural variation in the parvovirus capsid and its role in infection. Virology 1998;250:106-17
   PubMed Web of Science ®Google Scholar
• Weinberg JB, Matthews TJ, Cullen BR, et al. Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytes. J Exp Med 1991;174:1477-82
   PubMed Web of Science ®Google Scholar
• Bukrinsky MI, Sharova N, Dempsey MP, et al. Active nuclear import of human immunodeficiency virus type 1 preintegration complexes. Proc Natl Acad Sci USA 1992;89:6580-4
   PubMed Web of Science ®Google Scholar
• Lewis P, Hensel M, Emerman M, et al. Human immunodeficiency virus infection of cells arrested in the cell cycle. EMBO J 1992;11:3053-8
   PubMed Web of Science ®Google Scholar
• Dvorin JD, Malim MH. Intracellular trafficking of HIV-1 cores: journey to the center of the cell. Curr Top Microbiol Immunol 2003;281:179-208
   PubMed Web of Science ®Google Scholar
• Zennou V, Petit C, Guetard D, et al. HIV-1 genome nuclear import is mediated by a central DNA flap. Cell 2000;101:173-85
   PubMed Web of Science ®Google Scholar
• Yamashita M, Emerman M. Capsid is a dominant determinant of retrovirus infectivity in nondividing cells. J Virol 2004;78:5670-8
   PubMed Web of Science ®Google Scholar
• Yamashita M, Perez O, Hope TJ, et al. Evidence for direct involvement of the capsid protein in HIV infection of nondividing cells. PLoS Pathog 2007;3:1502-10
   PubMed Web of Science ®Google Scholar
• Fassati A, Görlich D, Harrison I, et al. Nuclear import of HIV-1 intracellular reverse transcription complexes is mediated by importin 7. EMBO J 2003;22:3675-85
   PubMed Web of Science ®Google Scholar
• Ebina H, Aoki J, Hatta S, et al. Role of Nup98 in nuclear entry of human immunodeficiency virus type 1 cDNA. Microbes Infect 2004;6:715-24
   PubMed Web of Science ®Google Scholar
• Christ F, Thys W, De Rijck J, et al. Transportin-SR2 imports HIV into the nucleus. Curr Biol 2008;18:1192-202
   PubMed Web of Science ®Google Scholar
• Luban J. HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase. Curr Biol 2008;18:R710-13
   PubMed Web of Science ®Google Scholar
• Yamashita M, Emerman M. Retroviral infection of non-dividing cells: old and new perspectives. Virology 2006;344:88-93
   PubMed Web of Science ®Google Scholar
• Yamashita M, Emerman M. The cell cycle independence of HIV infections is not determined by known karyophilic viral elements. PLoS Pathog 2005;1:e18
   PubMed Web of Science ®Google Scholar
• Fassati A. The cell cycle independence of HIV infections is not determined by known karyophilic viral elements. PLoS Pathog 2005;1:e18
   PubMedGoogle Scholar
• Limón A, Nakajima N, Lu R, et al. Wild-type levels of nuclear localization and human immunodeficiency virus type 1 replication in the absence of the central DNA flap. J Virol 2002;76:12078-86
   PubMed Web of Science ®Google Scholar
• Nisole S, Saïb A. Early steps of retrovirus replicative cycle. Retrovirology 2004;1:9
   PubMedGoogle Scholar
• Katz RA, Greger JG, Skalka AM. Effects of cell cycle status on early events in retroviral replication. J Cell Biochem 2005;94:880-9
   PubMed Web of Science ®Google Scholar
• Kukolj G, Katz RA, Skalka AM. Characterization of the nuclear localization signal in the avian sarcoma virus integrase. Gene 1998;223:157-63
   PubMed Web of Science ®Google Scholar
• Wagstaff KM, Jans DA. Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer. Biochem J 2007;406:185-202
   PubMed Web of Science ®Google Scholar
• Schirmbeck R, König-Merediz SA, Riedl P, et al. Priming of immune responses to hepatitis B surface antigen with minimal DNA expression constructs modified with a nuclear localization signal peptide. J Mol Med 2001;79:343-50
   PubMed Web of Science ®Google Scholar
• Zanta MA, Belguise-Valladier P, Behr JP. Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus. Proc Natl Acad Sci USA 1999;96:91-6
   PubMed Web of Science ®Google Scholar
• Subramanian A, Ranganathan P, Diamond SL. Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells. Nat Biotechnol 1999;17:873-7
   PubMed Web of Science ®Google Scholar
• Munkonge FM, Dean DA, Hillery E, et al. Emerging significance of plasmid DNA nuclear import in gene therapy. Adv Drug Deliv Rev 2003;55:749-60
   PubMed Web of Science ®Google Scholar
• Dean DA. Peptide nucleic acids: versatile tools for gene therapy strategies. Adv Drug Deliv Rev 2000;44:81-95
   PubMed Web of Science ®Google Scholar
• Brandén LJ, Smith CI. Bioplex technology: novel synthetic gene delivery system based on peptides anchored to nucleic acids. Methods Enzymol 2002;346:106-24
   PubMed Web of Science ®Google Scholar
• Brandén LJ, Mohamed AJ, Smith CI. A peptide nucleic acid-nuclear localization signal fusion that mediates nuclear transport of DNA. Nat Biotechnol 1999;17:784-7
   PubMed Web of Science ®Google Scholar
• Dean DA. Import of plasmid DNA into the nucleus is sequence specific. Exp Cell Res 1997;230:293-302
   PubMed Web of Science ®Google Scholar
• Längle-Rouault F, Patzel V, Benavente A, et al. Up to 100-fold increase of apparent gene expression in the presence of Epstein-Barr virus oriP sequences and EBNA1: implications of the nuclear import of plasmids. J Virol 1998;72:6181-5
   PubMed Web of Science ®Google Scholar
• Dean DA, Dean BS, Muller S, et al. Sequence requirements for plasmid nuclear import. Exp Cell Res 1999;253:713-22
   PubMed Web of Science ®Google Scholar
• Vacik J, Dean BS, Zimmer WE, et al. Cell-specific nuclear import of plasmid DNA. Gene Ther 1999;6:1006-14
   PubMed Web of Science ®Google Scholar
• Mesika A, Grigoreva I, Zohar M, et al. A regulated, NFkappaB-assisted import of plasmid DNA into mammalian cell nuclei. Mol Ther 2001;3:653-7
   PubMed Web of Science ®Google Scholar
• Miller AM, Dean DA. Cell-specific nuclear import of plasmid DNA in smooth muscle requires tissue-specific transcription factors and DNA sequences. Gene Ther 2008;15:1107-15
   PubMed Web of Science ®Google Scholar
• Young JL, Zimmer WE, Dean DA. Smooth muscle-specific gene delivery in the vasculature based on restriction of DNA nuclear import. Exp Biol Med (Maywood) 2008;233:840-8
   PubMed Web of Science ®Google Scholar
• Young JL, Benoit JN, Dean DA. Effect of a DNA nuclear targeting sequence on gene transfer and expression of plasmids in the intact vasculature. Gene Ther 2003;10:1465-70
   PubMed Web of Science ®Google Scholar
• Li S, Maclaughlin FC, Fewell JG, et al. Muscle-specific enhancement of gene expression by incorporation of SV40 enhancer in the expression plasmid. Gene Ther 2001;8:494-7
   PubMed Web of Science ®Google Scholar
• Kuramoto T, Nishikawa M, Thanaketpaisarn O, et al. Use of lipoplex-induced nuclear factor-kappaB activation to enhance transgene expression by lipoplex in mouse lung. J Gene Med 2006;8:53-62
   PubMed Web of Science ®Google Scholar
• Mesika A, Kiss V, Brumfeld V, et al. Enhanced intracellular mobility and nuclear accumulation of DNA plasmids associated with a karyophilic protein. Hum Gene Ther 2005;16:200-8
   PubMed Web of Science ®Google Scholar
• Breuzard G, Tertil M, Gonçalves C, et al. Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging. Nucleic Acids Res 2008;36:e71
   PubMedGoogle Scholar
• Carlotti F, Chapman R, Dower SK, et al. Activation of nuclear factor kappaB in single living cells. Dependence of nuclear translocation and anti-apoptotic function on EGFPRELA concentration. J Biol Chem 1999;274:37941-9
   PubMed Web of Science ®Google Scholar
• Hama S, Akita H, Ito R, et al. Quantitative comparison of intracellular trafficking and nuclear transcription between adenoviral and lipoplex systems. Mol Ther 2006;13:786-94
   PubMed Web of Science ®Google Scholar
• Lukacs GL, Haggie P, Seksek O, et al. Size-dependent DNA mobility in cytoplasm and nucleus. J Biol Chem 2000;275:1625-9
   PubMed Web of Science ®Google Scholar
• Remaut K, Sanders NN, Fayazpour F, et al. Influence of plasmid DNA topology on the transfection properties of DOTAP/DOPE lipoplexes. J Control Release 2006;115:335-43
   PubMed Web of Science ®Google Scholar
• Douglas KL. Toward development of artificial viruses for gene therapy: a comparative evaluation of viral and non-viral transfection. Biotechnol Prog 2008;24:871-83
   PubMed Web of Science ®Google Scholar
• Bremner KH, Seymour LW, Logan A, et al. Factors influencing the ability of nuclear localization sequence peptides to enhance nonviral gene delivery. Bioconjug Chem 2004;15:152-61
   PubMed Web of Science ®Google Scholar
• Carrière M, Escriou V, Savarin A, et al. Coupling of importin beta binding peptide on plasmid DNA: transfection efficiency is increased by modification of lipoplex's physico-chemical properties. BMC Biotechnol 2003;3:14
   PubMedGoogle Scholar