287
Views
22
CrossRef citations to date
0
Altmetric
Reviews

Endosomal disruptors in non-viral gene delivery

&
Pages 331-339 | Published online: 05 Mar 2010

Bibliography

  • Li SD, Huang L. Gene therapy progress and prospects: non-viral gene therapy by systemic delivery. Gene Ther 2006;13(18):1313-9
  • Minchin RF, Orr RJ, Cronin AS, The pharmacology of gene therapy. Croat Med J 1999;40(3):381-91
  • Vijayanathan V, Thomas T, Thomas TJ. DNA nanoparticles and development of DNA delivery vehicles for gene therapy. Biochem 2002;41(48):14085-94
  • Yang S, Coles DJ, Esposito A, Cellular uptake of self-assembled cationic peptide-DNA complexes: multifunctional role of the enhancer chloroquine. J Control Release 2009;135(2):159-65
  • Coles DJ, Yang S, Minchin RF, The characterization of a novel dendritic system for gene delivery by isothermal titration calorimetry. Biopolymers 2008;90(5):651-4
  • Khalil IA, Kogure K, Akita H, Uptake pathways and subsequent intracellular trafficking in nonviral gene delivery. Pharmacol Rev 2006;58(1):32-45
  • Lin C, Engbersen JF. Effect of chemical functionalities in poly(amido amine)s for non-viral gene transfection. J Control Release 2008;132(3):267-72
  • Torchilin VP. Cell penetrating peptide-modified pharmaceutical nanocarriers for intracellular drug and gene delivery. Biopolymers 2008;90(5):604-10
  • Thomas M, Klibanov AM. Non-viral gene therapy: polycation-mediated DNA delivery. Appl Microbiol Biotech 2003;62(1):27-34
  • von Gersdorff K, Sanders NN, Vandenbroucke R, The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type. Mol Ther 2006;14(5):745-53
  • Hansen CG, Nichols BJ. Molecular mechanisms of clathrin-independent endocytosis. J Cell Sci 2009;122(Pt 11):1713-21
  • Manunta M, Nichols BJ, Tan PH, Gene delivery by dendrimers operates via different pathways in different cells, but is enhanced by the presence of caveolin. J Immunol Methods 2006;314(1-2):134-46
  • Grant BD, Donaldson JG. Pathways and mechanisms of endocytic recycling. Nat Rev 2009;10(9):597-608
  • Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nat Rev 2009;10(9):609-22
  • Irvin JL, Irvin EM. Spectrophotometric and potentiometric evaluation of apparent acid dissociation exponents of various 4-Aminoquinoline˙s. J Am Chem Soc 1947;69(5):1091-9
  • Erbacher P, Roche AC, Monsigny M, Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes. Exp Cell Res 1996;225(1):186-94
  • Hashida H, Miyamoto M, Cho Y, Fusion of HIV-1 Tat protein transduction domain to poly-lysine as a new DNA delivery tool. Br J Cancer 2004;90(6):1252-8
  • Soundara Manickam D, Bisht HS, Wan L, Influence of TAT-peptide polymerization on properties and transfection activity of TAT/DNA polyplexes. J Control Release 2005;102(1):293-306
  • Wagner E, Cotten M, Foisner R, Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells. Proc Natl Acad Sci USA 1991;88(10):4255-9
  • Cheng J, Zeidan R, Mishra S, Structure-function correlation of chloroquine and analogues as transgene expression enhancers in nonviral gene delivery. J Med Chem 2006;49(22):6522-31
  • Ciftci K, Levy RJ. Enhanced plasmid DNA transfection with lysosomotropic agents in cultured fibroblasts. Int J Pharm 2001;218(1-2):81-92
  • Miriam B, Uta L, Renate L, Gene delivery with low molecular weight linear polyethylenimines. J Gene Med 2005;7(10):1287-98
  • Wattiaux R, Wattiaux-Deconinck S, Rutgeerts MJ, Influence of the injection of a sucrose solution on the properties of rat-liver lysosomes. Nature 1964;203:757-8
  • Cotten M, Langle-Rouault F, Kirlappos H, Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. Proc Natl Acad Sci USA 1990;87(11):4033-7
  • Gabrielson NP, Pack DW. Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells. J Control Release 2009;136(1):54-61
  • Minchin RF, Yang S. Transgene expression is markedly enhanced by chloroquine, but not by monensin or bafilomycin A1. Unpublished results
  • Allison JL, O'Brien RL, Hahn FE. DNA: reaction with chloroquine. Science 1965;149(688):1111-3
  • Schaffer DV, Fidelman NA, Dan N, Vector unpacking as a potential barrier for receptor-mediated polyplex gene delivery. Biotechnol Bioeng 2000;67(5):598-606
  • Boussif O, Lezoualc'h F, Zanta MA, A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA 1995;92(16):7297-301
  • Abdallah B, Hassan A, Benoist C, A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine. Hum Gene Ther 1996;7(16):1947-54
  • Boletta A, Benigni A, Lutz J, Nonviral gene delivery to the rat kidney with polyethylenimine. Hum Gene Ther 1997;8(10):1243-51
  • Goula D, Benoist C, Mantero S, Polyethylenimine-based intravenous delivery of transgenes to mouse lung. Gene Ther 1998;5(9):1291-5
  • Coll J-L, Chollet P, Brambilla E, In vivo delivery to tumors of DNA complexed with linear polyethylenimine. Hum Gene Ther 1999;10(10):1659-66
  • Helander IM, Alakomi HL, Latva-Kala K, Polyethyleneimine is an effective permeabilizer of gram-negative bacteria. Microbiol 1997;143(10):3193-9
  • Klemm AR, Young D, Lloyd JB. Effects of polyethyleneimine on endocytosis and lysosome stability. Biochem Pharmacol 1998;56(1):41-6
  • Kunath K, von Harpe A, Fischer D, Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine. J Control Release 2003;89(1):113-25
  • Kleemann E, Jekel N, Dailey LA, Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery. J Drug Target 2009;17(8):638-51
  • Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjug Chem 2002;4(5):372-9
  • Zhang ZY, Smith BD. High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: membrane bending model. Bioconjug Chem 2000;11(6):805-14
  • Bett AJ, Haddara W, Prevec L, An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3. Proc Natl Acad Sci USA 1994;91(19):8802-6
  • Han X, Bushweller JH, Cafiso DS, Membrane structure and fusion-triggering conformational change of the fusion domain from influenza hemagglutinin. Nat Struct Biol 2001;8(8):715-20
  • Zhelev DV, Stoicheva N, Scherrer P, Interaction of synthetic HA2 influenza fusion peptide analog with model membranes. Biophys J 2001;81(1):285-304
  • Lee H, Jeong JH, Park TG. PEG grafted polylysine with fusogenic peptide for gene delivery: high transfection efficiency with low cytotoxicity. J Control Release 2002;79(1-3):283-91
  • Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004;10(3):310-5
  • Wagner E, Plank C, Zatloukal K, Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle. Proc Natl Acad Sci USA 1992;89(17):7934-8
  • Futaki S, Masui Y, Nakase I, Unique features of a pH-sensitive fusogenic peptide that improves the transfection efficiency of cationic liposomes. J Gene Med 2005;7(11):1450-8
  • Li W, Nicol F, Szoka FC Jr. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv Rev 2004;56(7):967-85
  • Wyman TB, Nicol F, Zelphati O, Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers. Biochemistry 1997;36(10):3008-17
  • Ferrer-Miralles N, Vazquez E, Villaverde A. Membrane-active peptides for non-viral gene therapy: making the safest easier. Trends Biotechnol 2008;26(5):267-75
  • Kristeleit R, Stimson L, Workman P, Histone modification enzymes: novel targets for cancer drugs. Expert Opin Emerg Drugs 2004;9(1):135-54
  • Pikaart MJ, Recillas-Targa F, Felsenfeld G. Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators. Genes Dev 1998;12(18):2852-62
  • Tobias CA, Kim D, Fischer I. Improved recombinant retroviral titers utilizing trichostatin A. Biotechniques 2000;29(4):884-90
  • Okada T, Uchibori R, Iwata-Okada M, A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells. Mol Ther 2006;13(4):738-46
  • Nan X, Hyndman L, Agbi N, Potent stimulation of gene expression by histone deacetylase inhibitors on transiently transfected DNA. Biochem Biophys Res Commun 2004;324(1):348-54
  • Yasukawa K, Sawamura D, Goto M, Histone deacetylase inhibitors preferentially augment transient transgene expression in human dermal fibroblasts. Br J Dermatol 2007;157(4):662-9
  • Boya P, Gonzalez-Polo RA, Poncet D, Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine. Oncogene 2003;22(25):3927-36
  • Miller DK, Griffiths E, Lenard J, Cell killing by lysosomotropic detergents. J Cell Biol 1983;97(6):1841-51
  • Wilson PD, Hreniuk D, Lenard J. Reduced cytotoxicity of the lysosomotropic detergent N-dodecylimidazole after differentiation of HL60 promyelocytes. Cancer Res 1989;49(3):507-10
  • Kumamoto T, Araki S, Watanabe S, Experimental chloroquine myopathy: morphological and biochemical studies. Eur Neurol 1989;29(4):202-7
  • Butler D, Brown QB, Chin DJ, Cellular responses to protein accumulation involve autophagy and lysosomal enzyme activation. Rejuvenation Res 2005;8(4):227-37
  • Hamano T, Gendron TF, Causevic E, Autophagic-lysosomal perturbation enhances tau aggregation in transfectants with induced wild-type tau expression. Eur J Neurosci 2008;27(5):1119-30
  • Droga-Mazovec G, Bojic L, Petelin A, Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. J Biol Chem 2008;283(27):19140-50

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.